Overview
- Editors:
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Chris H. M. M. Bruyn
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University of Nijmegen Faculty of Medicine, Nijmegen, The Netherlands
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H. Anne Simmonds
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Guy’s Hospital Medical School, London, UK
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Mathias M. Müller
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University of Vienna, Vienna, Austria
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Table of contents (96 chapters)
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Immunopharmacology
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- G. Delespesse, J. P. R. M. van Laarhoven, H. Collet, C. H. M. M. De Bruyn
Pages 205-210
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- Irene S. Kazmers, A. Paulette Dalke, Peter E. Daddona, William N. Kelley
Pages 211-214
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- L. J. M. Spaapen, M. E. Dane, E. Toebes, B. Tepas, G. E. J. Staal, M. Duran et al.
Pages 215-220
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Purine Metabolism in Macrophages
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- Jerzy Barankiewicz, Amos Cohen
Pages 227-232
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Enzymes of Purine Metabolism as Markers for Malignancy
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- J. P. R. M. van Laarhoven, G. Th. Spierenburg, G. C. de Gast, T. J. Schouten, C. H. M. M. De Bruyn
Pages 233-240
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- Martin B. Van Der Weyden, Lynnette Hallam, T. Eng Gan, Peter H. Ellims
Pages 241-247
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- Wolf Gutensohn, Eckhard Thiel, Silvia Buschette
Pages 249-253
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- Boris Chechik, William Schrader, Ann Perets, Bernard Fernandes
Pages 255-259
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- Jacques Dornand, Jean-Claude Bonnafous, Jean Favero, Agnés Gartner, Jean-Claude Mani
Pages 261-266
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- Y. Nishida, N. Kamatani, T. Miyamoto
Pages 267-272
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- P. Chiba, M. Kraupp, H. Rumpold, M. M. Müller
Pages 273-278
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- Naoyuki Kamatani, Masaru Kubota, Erik H. Willis, Dennis A. Carson
Pages 279-283
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- Maria Błaszczyszyn, Mirosław Kłos
Pages 285-288
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- M. Torrent-Quetglas, M. R. Grau-Oliete, M. P. Rivera-Fillat
Pages 289-292
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- Elly Herbschleb-Voogt, Joop ten Kate, P. Meera Khan
Pages 293-298
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- Joop ten Kate, Juul Th. Wijnen, Elly Herbschleb-Voogt, Gerrit Griffioen, Fred T. Bosman, P. Meera Khan
Pages 299-303
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Nucleoside Metabolism and the Development of Anti-Leukemic Agents
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- A. L. Yu, S. Matsumoto, L. Bleeker, A. Alvarez, B. Bakay, W. L. Nyhan et al.
Pages 305-308
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- Erwin W. Gelfand, Jacob W. W. Lee, Amos Cohen
Pages 309-314
About this book
These two volumes, entitled "Purine Metabolism in Man IV" con tain the papers presented at the Fourth International Symposium on Human Purine and Pyrimidine Metabolism", held in Maastricht (The Netherlands), June 1982. The proceedings of the three previous meet ings in Tel Aviv (Israel, 1973), Baden (Austria, 1976) and Madrid (Spain, 1979) were also published by Plenum Press. In the past few years interest in purine and pyrimidine metabo lism under normal and pathological conditions has been growing rapid ly. Apart from the more or less classical topics such as hyperuricae mia, clinical gout and urolithiasis, an increasing number of papers relating to other fields have been presented at successive meetings. Knowledge derived from the study of purine metabolism in relation to lymphocyte function, for instance, has opened up new possibilities for immunomodulation and leukaemia chemotherapy, with eventual conse quences for other types of cancer. At previous meetings there have been pointers implicating purine metabolism in relation to normal cardiac and skeletal muscle function. During the present meeting mych new data on both issues have been re ported which indicate clear differences in the pathways of ATP metabo lism. The widening of the field of interest is also illustrated by the recent work on infectious disease: exploitation of the differences in purine metabolic pathways in certain parasites compared with those in human cells has resulted in new rationales for therapy being devel oped.
Editors and Affiliations
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University of Nijmegen Faculty of Medicine, Nijmegen, The Netherlands
Chris H. M. M. Bruyn
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Guy’s Hospital Medical School, London, UK
H. Anne Simmonds
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University of Vienna, Vienna, Austria
Mathias M. Müller