Advertisement

Uptake of AMP into K 562 and HL-60 Leukemic Cell Lines

  • P. Chiba
  • M. Kraupp
  • H. Rumpold
  • M. M. Müller
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 165)

Abstract

It is well known that the uptake of nucleotides by lymphocytes depends on the presence of an ecto 5′-nucleotidase (ecto 5′NT) (1,2). In this study the importance of ecto 5′NT for the uptake of AMP into two leukemic cell lines was investigated.

Keywords

Chronic Myelogenous Leukemia Nucleotidase Activity Chronic Myelogenous Leukemia Cell Incubation Tube Leucine Amino Peptidase 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    H. Fleit, M. Conklyn, R. D. Stebbins, and R. Silber, Function of 5′ nucleotidase in the uptake of adenosine from AMP by human lymphocytes, J. Biol, Chem. 250/23: 8889 (1975)Google Scholar
  2. 2.
    J. Dornand, J. C. Bonnafous, C. Gavach, and J. C. Mani, 5′ nucleotidase-facilitated adenosine transport by mouse lymphocytes, Biochimie 61: 973 (1979)PubMedCrossRefGoogle Scholar
  3. 3.
    C. B. Lozzio, B.B. Lozzio, Human chronic myelogenous leukemia cell line with positive Philadelphia chromosome, Blood 45: 321 (1975)PubMedGoogle Scholar
  4. 4.
    M. Jokinen, C. G. Gahmberg, and L. C. Anderson, Biosynthesis of the major human red cell sialoglycoprotein, glycophorin A, in a continuous cell line, Nature 279: 604 (1979)PubMedCrossRefGoogle Scholar
  5. 5.
    C. G. Gahmberg, and L. C. Anderson, K 562 human leukemic cell line with erythroid features, Semin. Hematol. 18: 72 (1981)PubMedGoogle Scholar
  6. 6.
    L. C. Anderson, M. Jokinen, and C. G. Gahmberg, Induction of erythroid differentiation in the human leukemic cell line K 562, Nature 278: 364 (1979)CrossRefGoogle Scholar
  7. 7.
    R. Gallagher, S. Collins, J. Truillo, K. McCredie, M. Ahearn, S. Tsai, R. Metzgar, G. Aulakh, R. Ting, F. Ruscetti, and R. Gallo, Characterisation of the continuous, differentiating myeloid cell line (HL-60) from a patient with acute promyelocytc leukemia, Blood 54: 713 (1979)PubMedGoogle Scholar
  8. 8.
    P. E. Newburger, M. E. Chovaniec, J. S. Greenberger, and H. J. Cohen, Functional changes in human leukemia cell line HL 60.Model for myeloid differentiation, J. Cell. Biol. 82: 314 (1979)CrossRefGoogle Scholar
  9. 9.
    M. Klingenberg, and E. Pfaff, Means of terminating reactions, in:“Methods in Enzymology, vol 10: 680 (1967)CrossRefGoogle Scholar
  10. 10.
    M. M. Müller, and G. Falkner, Uptake of hypoxanthin in human erythrocytes, in:Adv. Exp. Med. Biol. 76B:131 (1977)PubMedCrossRefGoogle Scholar
  11. 11.
    N. L. Edwards, D.B. Cassidy, and I. H. Fox, Lymphocyte ecto 5′nucleotidase deficiency in agammaglobulinemia, Science 201: 628 (1978)PubMedCrossRefGoogle Scholar
  12. 12.
    P. G. W. Plageman, R. M. Wohlhueter, Permeation of nucleosides, nucleic acid bases, and nucleotides in animal cells, in Curr. Top. in Membr. and Transport, vol 14: 225 (1980)CrossRefGoogle Scholar
  13. 13.
    R. M. Burger, and J. M. Lowenstein, 5′ nucleotidase from smooth muscle of small intestine and from brain. Inhibition by nucleotides, Biochemistry 114/11: 2362 (1975)CrossRefGoogle Scholar
  14. 14.
    I. Nagaoka, and T. Jamashita, Leucine amino peptidase as an ecto enzyme of polymorphonuclear neutrophils, BBA 598: 169 (1980)PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media New York 1984

Authors and Affiliations

  • P. Chiba
    • 1
  • M. Kraupp
    • 1
  • H. Rumpold
    • 1
  • M. M. Müller
    • 1
  1. 1.Department of Medical Chemistry Department of Surgery, Division of Clinical BiochemistryUniversity of ViennaAustria

Personalised recommendations