1. Iron increases lipid deposition via oxidative stress-mediated mitochondrial dysfunction and the HIF1α-PPARγ pathway

   • Chang-Chun Song
   • Kostas Pantopoulos
   • Zhi Luo

   Original Article 04 July 2022 Article: 394

   

2. Aspirin sensitivity of PIK3CA-mutated Colorectal Cancer: potential mechanisms revisited

   • Daniella C. N. Hall
   • Ralf A. Benndorf

   Review Open access 02 July 2022 Article: 393

   

3. RanGTPase links nucleo-cytoplasmic transport to the recruitment of cargoes into small extracellular vesicles

   • Sakalya Chavan
   • Deepak Khuperkar
   • Jomon Joseph

   Original Article 02 July 2022 Article: 392

   

4. ALYREF, a novel factor involved in breast carcinogenesis, acts through transcriptional and post-transcriptional mechanisms selectively regulating the short NEAT1 isoform

   • Christiane Klec
   • Erik Knutsen
   • Martin Pichler

   Original Article Open access 01 July 2022 Article: 391

   

5. -Omics potential of in vitro skin models for radiation exposure

   • Leyla A. Akh
   • Mohammad O. Ishak
   • Ethan M. McBride

   Review 01 July 2022 Article: 390

   

6. EWI2 prevents EGFR from clustering and endocytosis to reduce tumor cell movement and proliferation

   • Chenying Fu
   • Jie Wang
   • Xin A. Zhang

   Original Article 30 June 2022 Article: 389

   

7. Correction: Inflammation and neutrophil extracellular traps in cerebral cavernous malformation

   • Anthony C. Y. Yau
   • Maria Ascencion Globisch
   • Peetra U. Magnusson

   Correction Open access 29 June 2022 Article: 388

   

8. Vitamin K1 inhibits ferroptosis and counteracts a detrimental effect of phenprocoumon in experimental acute kidney injury

   • Benedikt Kolbrink
   • Friedrich Alexander von Samson-Himmelstjerna
   • Stefan Krautwald

   Original Article Open access 28 June 2022 Article: 387

   

9. Maternal gut microbiota Bifidobacterium promotes placental morphogenesis, nutrient transport and fetal growth in mice

   • Jorge Lopez-Tello
   • Zoe Schofield
   • Lindsay J. Hall

   Original Article Open access 28 June 2022 Article: 386

   

10. Single-cell RNA-sequencing of zebrafish hair cells reveals novel genes potentially involved in hearing loss

    • Fuping Qian
    • Guanyun Wei
    • Dong Liu

    Original Article 26 June 2022 Article: 385

    

11. Modelling human placental villous development: designing cultures that reflect anatomy

    • Joanna L. James
    • Abbey Lissaman
    • Lawrence W. Chamley

    Review Open access 26 June 2022 Article: 384

    

12. The distinct phenotype of primary adipocytes and adipocytes derived from stem cells of white adipose tissue as assessed by Raman and fluorescence imaging

    • Ewa Stanek
    • Marta Z. Pacia
    • Krzysztof Czamara

    Original Article Open access 25 June 2022 Article: 383

    

13. LINC00313 facilitates osteosarcoma carcinogenesis and metastasis through enhancing EZH2 mRNA stability and EZH2-mediated silence of PTEN expression

    • Chun-Yang Xing
    • Yu-Zhu Zhang
    • Li-Yuan Zhao

    Original Article 25 June 2022 Article: 382

    

14. Persistent Escherichia coli infection in renal tubular cells enhances calcium oxalate crystal–cell adhesion by inducing ezrin translocation to apical membranes via Rho/ROCK pathway

    • Rattiyaporn Kanlaya
    • Visith Thongboonkerd

    Original Article 24 June 2022 Article: 381

    

15. Effects of pH alterations on stress- and aging-induced protein phase separation

    • Xuejiao Jin
    • Min Zhou
    • Beidong Liu

    Review Open access 24 June 2022 Article: 380

    

16. Can the administration of platelet lysates to the brain help treat neurological disorders?

    • Ouada Nebie
    • Luc Buée
    • Thierry Burnouf

    Review 24 June 2022 Article: 379

    

17. Bidirectional regulation of synaptic SUMOylation by Group 1 metabotropic glutamate receptors

    • Marie Pronot
    • Gwénola Poupon
    • Stéphane Martin

    Original Article Open access 23 June 2022 Article: 378

    

18. Coupled fibromodulin and SOX2 signaling as a critical regulator of metastatic outgrowth in melanoma

    • Victor O. Oria
    • Hongyi Zhang
    • Lucia B. Jilaveanu

    Original Article Open access 23 June 2022 Article: 377

    

19. miRNA-486-5p: signaling targets and role in non-malignant disease

    • Adrianna Douvris
    • Jose Viñas
    • Kevin D. Burns

    Review Open access 22 June 2022 Article: 376

    

20. Mitochondrial FAD shortage in SLC25A32 deficiency affects folate-mediated one-carbon metabolism

    • Min-Zhi Peng
    • Yong-Xian Shao
    • Li Liu

    Original Article 21 June 2022 Article: 375

    

21. Inhibition of myostatin and related signaling pathways for the treatment of muscle atrophy in motor neuron diseases

    • Elena Abati
    • Arianna Manini
    • Stefania Corti

    Review Open access 21 June 2022 Article: 374

    

22. Neuronal microRNAs safeguard ER Ca²⁺ homeostasis and attenuate the unfolded protein response upon stress

    • Maria Paschou
    • Panagiota Papazafiri
    • Epaminondas Doxakis

    Original Article 21 June 2022 Article: 373

    

23. Historical and current perspectives on blood endothelial cell heterogeneity in the brain

    • Ryota L. Matsuoka
    • Luke D. Buck
    • Olivia A. Card

    Review Open access 20 June 2022 Article: 372

    

24. SHANK3 deficiency leads to myelin defects in the central and peripheral nervous system

    • Mariagiovanna Malara
    • Anne-Kathrin Lutz
    • Tobias M. Boeckers

    Original Article Open access 20 June 2022 Article: 371

    

25. Mitofusins: from mitochondria to fertility

    • Shanjiang Zhao
    • Nuo Heng
    • Huabin Zhu

    Review Open access 20 June 2022 Article: 370

    

26. Sulfavant A as the first synthetic TREM2 ligand discloses a homeostatic response of dendritic cells after receptor engagement

    • Carmela Gallo
    • Emiliano Manzo
    • Angelo Fontana

    Original Article Open access 20 June 2022 Article: 369

    

27. Restricting α-synuclein transport into mitochondria by inhibition of α-synuclein–VDAC complexation as a potential therapeutic target for Parkinson’s disease treatment

    • Megha Rajendran
    • María Queralt-Martín
    • Tatiana K. Rostovtseva

    Original Article 19 June 2022 Article: 368

    

28. Reciprocal regulation of Daxx and PIK3CA promotes colorectal cancer cell growth

    • Yen-Sung Huang
    • Chang-Chieh Wu
    • Hsiu-Ming Shih

    Original Article 19 June 2022 Article: 367

    

29. Mechanisms of chronic alcohol exposure-induced aggressiveness in cellular model of HCC and recovery after alcohol withdrawal

    • Constance Marié
    • Grégory Fouquet
    • Ingrid Marcq

    Original Article Open access 17 June 2022 Article: 366

    

30. Infection of lung megakaryocytes and platelets by SARS-CoV-2 anticipate fatal COVID-19

    • Aiwei Zhu
    • Fernando Real
    • Morgane Bomsel

    Original Article Open access 16 June 2022 Article: 365

    

31. Preclinical models of epithelial ovarian cancer: practical considerations and challenges for a meaningful application

    • Alessandra Ciucci
    • Marianna Buttarelli
    • Daniela Gallo

    Review Open access 16 June 2022 Article: 364

    

32. Mechanisms that regulate the activities of TET proteins

    • Kanak Joshi
    • Shanhui Liu
    • Jiwang Zhang

    Review 15 June 2022 Article: 363

    

33. Overexpression of laminin-5 gamma-2 promotes tumorigenesis of pancreatic ductal adenocarcinoma through EGFR/ERK1/2/AKT/mTOR cascade

    • Anuradha Kirtonia
    • Amit Kumar Pandey
    • Manoj Garg

    Original Article 14 June 2022 Article: 362

    

34. Melatonin drugs inhibit SARS-CoV-2 entry into the brain and virus-induced damage of cerebral small vessels

    • Erika Cecon
    • Daniela Fernandois
    • Ralf Jockers

    Original Article 13 June 2022 Article: 361

    

35. Phenazine derivatives attenuate the stemness of breast cancer cells through triggering ferroptosis

    • Yue Yang
    • Yuanyuan Lu
    • Lufeng Zheng

    Original Article 11 June 2022 Article: 360

    

36. Role of tertiary lymphoid organs in the regulation of immune responses in the periphery

    • Amit I. Bery
    • Hailey M. Shepherd
    • Daniel Kreisel

    Review 11 June 2022 Article: 359

    

37. Environment-mediated mutagenetic interference on genetic stabilization and circadian rhythm in plants

    • Nidhi
    • Pradeep Kumar
    • Mamta Sharma

    Review 10 June 2022 Article: 358

    

38. EIF4A3-induced circFIP1L1 represses miR-1253 and promotes radiosensitivity of nasopharyngeal carcinoma

    • Xiangqi Zhou
    • Guangjin Yuan
    • Sanyuan Tang

    Original Article 09 June 2022 Article: 357

    

39. Upregulation of MDH1 acetylation by HDAC6 inhibition protects against oxidative stress-derived neuronal apoptosis following intracerebral hemorrhage

    • Miao Wang
    • Chao Zhou
    • Guiyun Cui

    Original Article 09 June 2022 Article: 356

    

40. Recirculating Foxp3⁺ regulatory T cells are restimulated in the thymus under Aire control

    • Jonathan Charaix
    • Alexia Borelli
    • Magali Irla

    Original Article 09 June 2022 Article: 355

    

41. The protective effect of selenoprotein M on non-alcoholic fatty liver disease: the role of the AMPKα1–MFN2 pathway and Parkin mitophagy

    • Jingzeng Cai
    • Jiaqiang Huang
    • Ziwei Zhang

    Original Article 09 June 2022 Article: 354

    

42. Comparative interactome analysis of the PRE DNA-binding factors: purification of the Combgap-, Zeste-, Psq-, and Adf1-associated proteins

    • Darya Chetverina
    • Nadezhda E. Vorobyeva
    • Maksim Erokhin

    Original Article 09 June 2022 Article: 353

    

43. Inhibition of ALG3 stimulates cancer cell immunogenic ferroptosis to potentiate immunotherapy

    • Pei Liu
    • Cha Lin
    • Xinjian Liu

    Original Article 08 June 2022 Article: 352

    

44. Microencapsulation-based cell therapies

    • Safiya Naina Marikar
    • Assam El-Osta
    • Keith Al-Hasani

    Review Open access 08 June 2022 Article: 351

    

45. Potential neuroprotective effect of stem cells from apical papilla derived extracellular vesicles enriched by lab-on-chip approach during retinal degeneration

    • Hanieh Hadady
    • Fereshteh Karamali
    • Mohammad Hossein Nasr-Esfahani

    Original Article 07 June 2022 Article: 350

    

46. Biological aspects in controlling angiogenesis: current progress

    • Mohsen Akbarian
    • Luiz E. Bertassoni
    • Lobat Tayebi

    Review 07 June 2022 Article: 349

    

47. Loss of core-fucosylation of SPARC impairs collagen binding and contributes to COPD

    • Tsai-Jung Wu
    • Sheng-Hung Wang
    • John Yu

    Original Article Open access 07 June 2022 Article: 348

    

48. Circulating SSEA-1⁺ stem cell-mediated tissue repair in allergic airway inflammation

    • Chiao-Juno Chiu
    • Chien-Chia Liao
    • Bor-Luen Chiang

    Original Article Open access 07 June 2022 Article: 347