Modifications of the human tRNA anticodon loop and their associations with genetic diseases Jing-Bo ZhouEn-Duo WangXiao-Long Zhou Review 04 October 2021 Pages: 7087 - 7105
Recapitulating pancreatic cell–cell interactions through bioengineering approaches: the momentous role of non-epithelial cells for diabetes cell therapy Zahra GhezelayaghMahsa ZabihiYaser Tahamtani Review 06 October 2021 Pages: 7107 - 7132
The molecular identity of the TLQP-21 peptide receptor Bhavani S. SahuMegin E. NguyenAlessandro Bartolomucci Review Open access 09 October 2021 Pages: 7133 - 7144
The multifunctional RNA-binding protein Staufen1: an emerging regulator of oncogenesis through its various roles in key cellular events Shekoufeh AlmasiBernard J. Jasmin Review Open access 11 October 2021 Pages: 7145 - 7160
Beyond immunosuppressive effects: dual roles of myeloid-derived suppressor cells in bone-related diseases Zhiguo LingChuan YangYueqi Chen Review 11 October 2021 Pages: 7161 - 7183
Amyloid β structural polymorphism, associated toxicity and therapeutic strategies Ofek OrenRan TaubeNiv Papo Review 13 October 2021 Pages: 7185 - 7198
RIPK3 signaling and its role in the pathogenesis of cancers Shanhui LiuKanak JoshiJiwang Zhang Review 15 October 2021 Pages: 7199 - 7217
Developmentally regulated GTPases: structure, function and roles in disease Christian A. E. WestripQinqin ZhuangMathew L. Coleman Review Open access 19 October 2021 Pages: 7219 - 7235
The influenza virus RNA polymerase as an innate immune agonist and antagonist Elizaveta ElshinaAartjan J. W. te Velthuis Review Open access 22 October 2021 Pages: 7237 - 7256
The Hsp70–Hsp90 go-between Hop/Stip1/Sti1 is a proteostatic switch and may be a drug target in cancer and neurodegeneration Kaushik BhattacharyaDidier Picard Review Open access 22 October 2021 Pages: 7257 - 7273
The impact of obesity on adipocyte-derived extracellular vesicles Hiu Yee KwanMinting ChenBaisen Chen Review 22 October 2021 Pages: 7275 - 7288
Neural circuit mechanisms that govern inter-male attack in mice Xi ZhaXiao-Hong Xu Review 23 October 2021 Pages: 7289 - 7307
Alpha and beta myosin isoforms and human atrial and ventricular contraction Jonathan WalklateCecilia FerrantiniMichael A. Geeves Review Open access 26 October 2021 Pages: 7309 - 7337
Key features of the POU transcription factor Oct4 from an evolutionary perspective Evgeny I. BakhmetAlexey N. Tomilin Review 26 October 2021 Pages: 7339 - 7353
MicroRNA-34a: the bad guy in age-related vascular diseases Angela RaucciFederica MacrìEstella Zuccolo Review Open access 26 October 2021 Pages: 7355 - 7378
Axonal mRNA localization and translation: local events with broad roles Lichao LiJun YuSheng-Jian Ji Review 26 October 2021 Pages: 7379 - 7395
Genomics of Alzheimer’s disease implicates the innate and adaptive immune systems Yihan LiSimon M. LawsBen J. Gu Review 27 October 2021 Pages: 7397 - 7426
The crosstalk between viral RNA- and DNA-sensing mechanisms Chunmei CaiYan-Dong TangChunfu Zheng Review 29 October 2021 Pages: 7427 - 7434
The lysosome as an imperative regulator of autophagy and cell death Kewal Kumar MahapatraSoumya Ranjan MishraSujit Kumar Bhutia Review 30 October 2021 Pages: 7435 - 7449
Dihydrolipoamide dehydrogenase, pyruvate oxidation, and acetylation-dependent mechanisms intersecting drug iatrogenesis I. F. DuarteJ. CaioM. F. B. Silva Review 31 October 2021 Pages: 7451 - 7468
Hypothalamic endocannabinoids in obesity: an old story with new challenges Cristina MiralpeixAna Cristina RegueraRosalía Rodríguez-Rodríguez Review Open access 31 October 2021 Pages: 7469 - 7490
Mitigating the pro-oxidant state and melanogenesis of Retinitis pigmentosa: by counteracting mitochondrial dysfunction Giovanni PaganoFederico V. PallardóMarco Trifuoggi Review 31 October 2021 Pages: 7491 - 7503
OncomiRs miR-106a and miR-17 negatively regulate the nucleoside-derived drug transporter hCNT1 Clara Boces-PascualAida Mata-VentosaSandra Pérez-Torras Original Article Open access 13 October 2021 Pages: 7505 - 7518
Structure–function relationships explain CTCF zinc finger mutation phenotypes in cancer Charles G. BaileyShailendra GuptaJohn E. J. Rasko Original Article Open access 16 October 2021 Pages: 7519 - 7536
Extracellular vesicle proteomes of two transmissible cancers of Tasmanian devils reveal tenascin-C as a serum-based differential diagnostic biomarker Camila EspejoRichard WilsonA. Bruce Lyons Original Article 16 October 2021 Pages: 7537 - 7555
Kappa but not delta or mu opioid receptors form homodimers at low membrane densities Kristina CechovaChenyang LanMaximilian H. Ulbrich Original Article Open access 17 October 2021 Pages: 7557 - 7568
The Na+-activated K+ channel Slack contributes to synaptic development and plasticity Lucas MattThomas PhamRobert Lukowski Original Article Open access 18 October 2021 Pages: 7569 - 7587
Extracellular vesicle release and uptake by the liver under normo- and hyperlipidemia Krisztina NémethZoltán VargaViola Tamási Original Article Open access 19 October 2021 Pages: 7589 - 7604
Functional molecular switches of mammalian G protein-coupled bitter-taste receptors Jérémie TopinCédric BouyssetJérôme Golebiowski Original Article 23 October 2021 Pages: 7605 - 7615
Nuclear import receptors and hnRNPK mediates nuclear import and stress granule localization of SIRLOIN Jialin YaoYingfeng TuQingxiang Sun Original Article 23 October 2021 Pages: 7617 - 7633
Sam68 contributes to intestinal inflammation in experimental and human colitis Wendy A. GoodmanShrikanth C. BasavarajappaParameswaran Ramakrishnan Original Article 24 October 2021 Pages: 7635 - 7648
O2 permeability of lipid bilayers is low, but increases with membrane cholesterol Samer Al-SamirFabian ItelVolker Endeward Original Article Open access 25 October 2021 Pages: 7649 - 7662
MiR-409-3p targets a MAP4K3-ZEB1-PLGF signaling axis and controls brown adipose tissue angiogenesis and insulin resistance Dakota Becker-GreeneHao LiBasak Icli Original Article 26 October 2021 Pages: 7663 - 7679
Recombinant thrombomodulin domain 1 rescues pathological angiogenesis by inhibition of HIF-1α-VEGF pathway Yi-Hsun HuangCheng-Hsiang KuoHua-Lin Wu Original Article 27 October 2021 Pages: 7681 - 7692
Metabolic regulation of RA macrophages is distinct from RA fibroblasts and blockade of glycolysis alleviates inflammatory phenotype in both cell types Sadiq UmarKarol PalasiewiczShiva Shahrara Original Article 27 October 2021 Pages: 7693 - 7707
GRP78 facilitates M2 macrophage polarization and tumour progression Heng ZhangShao-Qiang WangRi Chen Original Article 28 October 2021 Pages: 7709 - 7732
Identification by proximity labeling of novel lipidic and proteinaceous potential partners of the dopamine transporter Dolores PiniellaElena Martínez-BlancoFrancisco Zafra Original Article Open access 28 October 2021 Pages: 7733 - 7756
Apoptosis resistance of senescent cells is an intrinsic barrier for senolysis induced by cardiac glycosides Pavel I. DeryabinAlla N. ShatrovaAleksandra V. Borodkina Original Article Open access 29 October 2021 Pages: 7757 - 7776
Snake venom phospholipase A2s exhibit strong virucidal activity against SARS-CoV-2 and inhibit the viral spike glycoprotein interaction with ACE2 Andrei E. SiniavinMaria A. StreltsovaYuri N. Utkin Original Article 29 October 2021 Pages: 7777 - 7794
Effect of space flight on the behavior of human retinal pigment epithelial ARPE-19 cells and evaluation of coenzyme Q10 treatment Francesca CialdaiDavide BologniniMatteo Lulli Original Article 29 October 2021 Pages: 7795 - 7812
Pharmacological chaperones improve intra-domain stability and inter-domain assembly via distinct binding sites to rescue misfolded CFTR Nesrine BaatallahAhmad ElbahnsiAlexandre Hinzpeter Original Article 29 October 2021 Pages: 7813 - 7829
α-Klotho released from HK-2 cells inhibits osteogenic differentiation of renal interstitial fibroblasts by inactivating the Wnt–β-catenin pathway Zewu ZhuShuhao RuanHequn Chen Original Article 01 November 2021 Pages: 7831 - 7849
Vascular adhesion protein-1 defines a unique subpopulation of human hematopoietic stem cells and regulates their proliferation Imtiaz Iftakhar-e-KhudaAlberto PessiaSirpa Jalkanen Original Article Open access 01 November 2021 Pages: 7851 - 7872
Role of Akt isoforms in neuronal insulin signaling and resistance Medha SharmaChinmoy Sankar Dey Original Article 01 November 2021 Pages: 7873 - 7898
Inhibition of the hERG potassium channel by phenanthrene: a polycyclic aromatic hydrocarbon pollutant Ehab Al-MoubarakHolly A. ShielsJules C. Hancox Original Article Open access 02 November 2021 Pages: 7899 - 7914
Correction to: TP63 links chromatin remodeling and enhancer reprogramming to epidermal differentiation and squamous cell carcinoma development Mei YiYixin TanBo Xiang Correction 02 November 2021 Pages: 7915 - 7915