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The Molecular Basis of Viral Replication

  • Book
  • © 1987

Overview

Part of the book series: NATO Science Series A: (NSSA, volume 136)

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Table of contents (22 chapters)

  1. Viruses at the molecular level

  2. The basic processes involved in viral replication

  3. Interference and interferon

  4. The strategies of replication

Keywords

About this book

the discovery of the "splicing" of the gene transcripts, the list would include the whole molecular genetics of the lambda bacteriophage, the notions of "promotor," "repressor," and "integration," the discovery of the reverse flow of genetic information, the very existence of oncogenes, the S'-terminal "cap" struc­ ture of eukaryotic mRNAs, ... Electronmicroscopy, ultracentrifugation and tissue culture were the landmarks on the way of the young science. During the past few years, however, a major (and not so silent) revolution took place: recombinant DNA technology with all its might entered in our laboratories, and restriction mapping of cloned genomes and sequencing gels have replaced plaque counting and sucrose gradients. The new techniques have made it possible to "dissect" the entire genome of a virus at the molecular level, and studies that would have been dreamt of just in the mid-seventies became the everyday experiments of our days. With new insight into the structure of viral genomes, and a deeper understanding of the mechanisms that regulate their expression, our view of viruses was bound to change: this volume bears witness to this impressive advance.

Editors and Affiliations

  • The Institute for Virology, University of Rome, Rome, Italy

    R. Perez Bercoff

Bibliographic Information

  • Book Title: The Molecular Basis of Viral Replication

  • Editors: R. Perez Bercoff

  • Series Title: NATO Science Series A:

  • DOI: https://doi.org/10.1007/978-1-4684-5350-8

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer Science+Business Media New York 1987

  • Softcover ISBN: 978-1-4684-5352-2Published: 14 March 2013

  • eBook ISBN: 978-1-4684-5350-8Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: XXIII, 579

  • Number of Illustrations: 85 b/w illustrations

  • Topics: Medical Microbiology

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