Abstract
Hemorrhoids are a normal component of anorectal anatomy. The terms “hemorrhoids” – as used by patients – or “hemorrhoidal disease” refer to the state of symptoms attributed to the vascular cushions present in the anal canal. It is critical for both surgeons and patients alike to consider this fact when evaluating and managing hemorrhoidal symptoms, as patients may desire removal of hemorrhoids, whereas control of symptoms should be the primary treatment goal.
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References
Thomson WH. The nature of haemorrhoids. Br J Surg. 1975;62(7):542–52.
Thulesius O, Gores JE. Arterio-venous anastomoses in the anal region with reference to the pathogenesis and treatment of haemorrhoids. Acta Chir Scand. 1973;139(5):476–8.
Parnaud E, Guntz M, Bernard A, et al. Anatomie normale macroscopique et microscopique du reseau vasculaire hemorrhoidal. Arch Fr Mal Appar Dig. 1976;65:501.
Hansen HH. Pathomorphologieund therapie des hamorrhoidalleidens. Hautartzt. 1977;28:364.
Lestar B, Penninck F, Kerremans R. The composition of anal basal pressure. An in vivo and in vitro study in man. Int J Colorectal Dis. 1989;4(2):118–22.
Haas PA, Fox TA, Hass GP. The pathogenesis of hemorrhoids. Dis Colon Rectum. 1984;27(7):442–50.
Galizia G, Lieto E, Castellano P, Pelosio L, Imperator V, Pigantelli C. Lateral internal sphincterotomy together with haemorhroidectomy for treatment for haemorrhoids: a randomized prospective study. Eur J Surg. 2000;166:223–8.
Farouk R, Duthie GS, MacGregor AB, Bartolo DC. Sustained internal sphincter hypertonia in patients with chronic anal fissure. Dis Colon Rectum. 1994;37:424–9.
Loder PB, Kamm MA, Nicholls RJ, Phillips RK. Haemorrhoids: pathology, pathophysiology, and aetiology. Br J Surg. 1994;81(7):946–54.
Johanson JF, Sonnenberg A. The prevalence of hemorrhoids and chronic constipation. An epidemiologic study. Gastroenterology. 1990;98(2):380–6.
Adams PF, Hendershot GE, Marano MA. Current estimates from the National Health Interview Survey, 1996. Natl Center Health Stat Vital Health Stat. 1999;10(200):1–203.
Abramowitz L, Godeberge P, Staumont G, Soudan D. Clinical practice guidelines for the treatment of hemorrhoid disease. Gastroenterol Clin Biol. 2001;25(6–7):674–702.
National Center for Health Statistics. (Technical Appendix from Vital Statistics of the United States: Mortality). 2002. Hyattsville, Maryland: 2004.
Johanson JF, Sonnenberg A. Temporal changes in the occurrence of hemoohids in the United States and England. Dis Colon Rectum. 1991;34(7):585–91.
Burt CW, Schappert SM. Ambulatory care visits to physician offices, hospital outpatient departments, and emergency departments: United States, 1999–2000. Natl Center Health Stat Vital Health Stat. 2004;13(157):1–70.
Helmick CG, Griffin PM, Addiss DG, Tauxe RV, and Juranek DD. Chapter 3 in Everhart, James. E. (ed.), Digestive Diseases in the United States: Epidemiology and Impact. U.S. Dept. of Health and Human Services, Public Health Service, National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases: U.S. Government Printing Office, May 1994, NIH Pub. No. 94-1447, pp. 85–123
Kozak LJ, Owings MF, Hall MJ. National Hospital Discharge Survey: 2002 annual summary with detailed diagnosis and procedure data. Natl Center Health Stat Vital Health Stat. 2005;13(158):1–199.
Johanson JF. Hemorrhoids. In: Everhart JE, editor. Digestive diseases in the United States: epidemiology and impact. US Department of Health and Human Services, Public Health Service, National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases. Washington, DC: US Government Printing Office, 1994; NIH Publication No. 94-1447 pp. 271–298.
Everhart JE, ed. The burden of digestive diseases in the United States. US Department of Health and Human Services, Public Health Service, National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases. Washington, DC: US Government Printing Office, 2008; NIH Publication No. 09-6443.
Banov Jr J, Kneopp Jr JF, Erdman JH, Alia RT. Management of hemorrhoidal disease. J S C Med Assoc. 1985;81(7):398–401.
Senagore AJ, Singer M, Abcarian H, et al. A prospective, randomized, controlled, multicenter trial comparing stapled hemorrhoidopexy and Ferguson hemorrhoidectomy: peripoperative and one year result. Dis Colon Rectum. 2004;47(11):824–36.
O’Donnell LJD, Heaton KW. Pseudo-diarrhea in the irritable bowel syndrome: patients’ records of stool form reflect transit time while stool frequency does not. Gut. 1988;29:A1455.
Armstrong DN. Multiple hemorrhoidal ligation: a prospective, randomized trial evaluating a new technique. Dis Colon Rectum. 2003;46(2):179–86.
Segal WN, Greenberg PD, Rockey DC, Cello JP, McQuaid KR. The outpatient evaluation for hematochezia. Am J Gastroenterol. 1998;93(2):179–82.
Church JM. Analysis of the colonoscopic findings in patients with rectal bleeding according to the pattern of their presenting symptoms. Dis Colon Rectum. 1991;34:391–5.
Rex DK, Bond JH, Winawer S, et al. Quality in the technical performance of colonoscopy and the continuous quality improvement process for colonoscopy: recommendations of the U.S. Multi-Society Task Force on colorectal cancer. Am J Gastroenterol. 2002;97:1296–308.
Cataldo P, Ellis N, Gregorcyk S, et al. Practice parameters for the management of hemorrhoids (Revised). Dis Colon Rectum. 2005;48:189–94.
Clinical Practice Committee, American Gatroenterological Association. American Gastroenterological Association medical position statement; diagnosis and treatment of hemorrhoids. Gastroenterology 2004; 126(5); 1461–1462.
Korkis AM, McDougall CJ. Rectal bleeding in patients less than 50 years of age. Dig Dis Sci. 1995;40(7):1520–3.
Nakama H, Kamijo N, Fujimori K, Horiuchi A, Abdul Fattah S, Zhang B. Immunochemical fecal occult blood test is not suitable for diagnosis of hemorrhoids. Am J Med. 1997;102(6):551–4.
Madoff RD, Fleshman JW. American Gastroenterological Association technical review on the diagnosis and treatment of hemorrhoids. Gastroenterology. 2004;126(5):1463–73.
Kluiber RM, Wolff BG. Evaluation of anesmia caused by hemorrhoidal bleeding. Dis Colon Rectum. 1994;37(10):1006–7.
USDA, Agricultural research service. Dietary Intake Data from the Third National Health and Nutrition Examination Survey (NHANES III) 1988.
Moesgaard F, Nielsen ML, Hansen JB, Knudse JT. High fiber diet resuces bleeding and pain in patients with hemorrhoids: a double-blind trial of Vi-Siblin. Dis Colon Rectum. 1982;25(2):454–6.
Broader JH, Gunn IF, Alexander-Williams J. Evaluation of a bulk-forming evacuant in the management of haemorrhoids. Br J Surg. 1974;61(2):142–4.
Webster DJ, Gough DC, Craven JL. The use of bulk evacuant in patients with haemorrhoids. Br J Surg. 1978;65(4):291–2.
Perez-Miranda M, Gomez-Cedenilla A, Leon-Colombo T, Pajares J, Mate-Jimenez J. Effect of fiber supplements on internal bleeding hemorrhoids. Hepatogastroenterology. 1996;43(12):1504–7.
Alonso-Coello P, Mills E, Heels-Ansdell D, López-Yarto M, Zhou Q, Johanson JF, et al. Fiber for the treatment of hemorrhoids complications: a systematic review and meta-analysis. Am J Gastroenterol. 2006;101(1):181–8.
Tejirian T, Abbas MA. Sitz bath: where is the evidence? Scientific basis for a common practice. Dis Colon Rectum. 2005;48(12):2336–40.
Smith PD. Neutrophil activation and mediators of inflammation in chronic venous insufficiency. J Vasc Res. 1999;36:24–36.
Shoab SS, Porter J, Scurr JH, Coleridge-Smith PD. Endothelial activation response to oral micronised flavonoid therapy in patients with chronic venous disease – a prospective study. Eur J Vasc Endovasc Surg. 1999;17:313–8.
Struckmann JR. Clinical efficacy of micronized purified flavonoid fraction: an overview. J Vasc Res. 1999;36:37–41.
Ibañez L, Ballarín E, Vidal X, Laporte JR. Agranulocytosis associated with calcium dobesilate. Clinical course and risk estimation with the case-control and the case-population approaches. Eur J Clin Pharmacol. 2000;56:763–7.
Godeberge P. Daflon 500 mg in the treatment of hemorrhoidal disease: a demonstrated efficacy in comparison with placebo. Angiology. 1994;45:574–8.
Cospite M. Double-blind, placebo-controlled evaluation of clinical activity and safety of Daflon 500 mg in the treatment of acute hemorrhoids. Angiology. 1994;45:566–73.
Thanapongsathorn W, Vajrabukka T. Clinical trial of oral disomin (Daflon) in the treatment of hemorrhoids. Dis Colon Rectum. 1992;35(11):1085–8.
Misra MC, Parshad R. Randomized clinical trial of micronized flavonoids in the early control of bleeding from acute internal haemorrhoids (comment). Br J Surg. 2000;87(7):868–72.
Ho YH, Foo CL, Seow-Choen F, Goh HS. Prospective randomized controlled trial of a micronized flavonidic fraction to reduce bleeding after haemorrhoidectomy. Br J Surg. 1995;82(8):1034–5.
Wijayanegara H, Mose JC, Achmad L, Sobarna R, Permadi W. A clinical trial of hydroxyethylrutoside in the treatment of haemorrhoids of pregnancy. J Int Med Res. 1992;20(1):54–60.
Squadrito F, Altavilla D, Oliaro Bosso S. Double blind, randomized clinical trial of troxerutin-carbazochrome in patients with hemorrhoids. Eur Rev Med Pharmacol Sci. 2000;4(1–2):21–4.
Mentes BB, Gorgul A, Tatlicioglu E, Ayoglu F, Unal S. Efficacy of calcium dobesilate in treating acute attacks of hemorrhoidal disease. Dis Colon Rectum. 2001;4(10):1489–95.
Alonso-Coello P, Zhou Q, Martinez-Zapata MJ, Heels-Ansdell D, Johanson JF, Guyatt G. Meta-analysis of flavonoids for the treatment of haemorrhoids. Br J Surg. 2006;93:909–20.
Budding J. Solo operated haemorrhoid ligator rectoscope. A report on 200 consecutive bandings. Int J Colorectal Dis. 1997;12(1):42–4.
Berkelhammer C, Moosvi SB. Retroflexed endoscopic band ligation of bleeding internal hemorrhoids. Gastroinest Endosc. 2002;55(4):532–7.
Su MY, Chiu CT, Wu CS, et al. Endoscopic hemorrhoidal ligation of symptomatic internal hemorrhoids. Gastrointest Endosc. 2003;58(6):871–4.
Ramzisham AR, Sagap I, Nadeson S, Ali IM, Hasni MJ. Prospective randomized clinical trial on suction elastic band ligator versus forceps ligator in the treatment of haemorrhoids. Asian J Surg. 2005;28(4):241–5.
Khaliq T, Shah SA, Mehboob A. Outcome of rubber band ligation of haemorrhoids using suction ligator. J Ayub Med Coll Abbottabad. 2004;16(4):34–7.
O’Regan PH. Disposable device and a minimally invasive technique for rubber band ligation of haemorrhoids. Dis Colon Rectum. 1999;42(5):683–5.
Mattana C, Maria G, Pescatori M. Rubber band ligation of hemorrhoids and rectal mucosal prolapse in constipated patients. Dis Colon Rectum. 1989;32(5):372–5.
Lau WY, Chow HP, Poon GP, Wong SH. Rubber band ligation of three primary hemorrhoids in a single session. A safe an effective procedure. Dis Colon Rectum. 1982;25(4):336–9.
Khubchandani IT. A randomized comparison of single and multiple rubber band ligations. Dis Colon Rectum. 1983;26(11):705–8.
Poon GP, Chu KW, Lau WY. Conventional vs. triple rubber band ligation for hemorrhoids. A prospective, randomized trial. Dis Colon Rectum. 1986;29(12):836–8.
Lee HH, Spencer RJ, Beart Jr RW. Multiple hemorrhoidal bandings in a single session. Dis Colon Rectum. 1994;37(1):37–41.
Law WL, Chu KW. Triple rubber band ligation for hemorrhoids: prospective, randomized trial of use of local anesthetic injection. Dis Colon Rectum. 1999;42(3):363–6.
Ambrose NS, Hares MM, Alexander Williams J, Keighley MR. Prospective randomized comparison of photocoagulation and rubber band ligation in treatment of haemorrhoids. Br Med J (Clin Res Ed). 1983;286(6375):1389–91.
Templeton JL, Spence RA, Kennedy TL, Parks TG, Mackenzie G, Hanna WA. Comparison of infrared coagulation and rubber band ligation for first and second degree haemorrhoids: a randomised prospective clinical trial. Br Med J (Clin Red Ed). 1983;286(6375):1387–9.
Walker AJ, Leiceste RJ, Nicholls RJ, Mann CV. A prospective study of infrared coagulation injection and rubber band ligation in the treatment of haemorrhoids. Int J Colorectal Dis. 1990;5(2):113–6.
Bat L, Melzer E, Koler M, Dreznick Z, Shemesh E. Complications of rubber band ligation of symptomatic internal hemorrhoids. Dis Colon Rectum. 1993;36(3):287–90.
O’Hara VS. Fatal clostridial infection following hemorrhoidal banding. Dis Colon Rectum. 1980;23(8):570–1.
Russell TR, Donohue JH. Hemorrhoidal banding. A warning. Dis Colon Rectum. 1985;25(5):291–3.
Scarpa FJ, Hillis W, Sabetta JR. Pelvic cellulitis: a life threatening complication of hemorrhoidal banding. Surgery. 1988;103(3):383–5.
Quevedo-Bonilla G, Farkas AM, Abcarian H, Hambrick E, Orsay CP. Septic complications of hemorrhoidal banding. Arch Surg. 1988;123(5):650–1.
Shemesh EI, Kodner IJ, Fry RD, Neufeld DM. Sever complications of rubber band ligation of internal hemorrhoids. Dis Colon Rectum. 1987;30(3):199–200.
Wrobleski DE, Corman ML, Veidenheimer MC, Coller JA. Long-term evaluation of rubber ring ligation in hemorrhoidal disease. Dis Colon Rectum. 1980;23(7):478–82.
Savioz D, Roche B, Glauser T, Dobrinov A, Ludwig C, Marti MC. Rubber band ligation of hemorrhoids: relapse as a function of time. Int J Colorectal Dis. 1998;12(4):154–6.
Bayer I, Myslovaty B, Picovsky BM. Rubber band ligation of hemorrhoids. Convenient and economic treatment. J Clin Gastroenterol. 1996;23(1):50–2.
Dennison A, Whiston RJ, Rooney S, Chadderton RD, Wherry DC, Morris DL. A randomized comparison of infrared photocoagulation with bipolar diathermy for the outpatient treatment of hemorrhoids. Dis Colon Rectum. 1990;33(1):32–4.
Peon AC, Felt-Bersma RJ, Cuesta MA, Deville W, Meuwissen SG. A randomized controlled trial of rubber band ligation versus infra-red coagulation in the treatment of internal haemorrhoids. Eur J Gastroenterol Hepatol. 2000;12(5):535–9.
Hinton CP, Morris DL. A randomized trial comparing direct current therapy and bipolar diathermy in the outpatient treatment of third-degree hemorrhoids. Dis Colon Rectum. 1990;33(11):931–2.
Randall GM, Jensen DM, Machicado GA, et al. Prospective randomized comparative study of bipolar versus direct current electrocoagulation for treatment of bleeding internal hemorrhoids. Gastrointest Endosc. 1994;40(4):403–10.
Jensen DM, Jutabha R, Machicado GA, et al. Prospective randomized comparative study of bipolar electrocoagulation versus hater probe for treatment of chronically bleeding internal hemorrhoids. Gastrointest Endosc. 1997;46(5):435–43.
Norman DA, Newton R, Nicholas GV. Direct current electrotherapy of internal hemorrhoids: an effective, safe, and painless outpatient approach. Am J Gastroenterol. 1989;84(5):482–7.
Zinberg SS, Stern DH, Furman DS, Wittles JM. A personal experience in comparing three nonoperative techniques for treating internal hemorrhoids. Am J Gastroenterol. 1989;84(5):488–92.
Varma JS, Chung SC, Li AK. Propsective randomized comparison of current coagulation and infection sclerotherapy for the outpatient treatment of haemorrhoids. Int J Colorectal Dis. 1991;6(1):42–5.
Sim AJ, Murie JA, Mackenzie I. Three year follow up study on the treatment of first and second degree hemorrhoids by sclerosant injection or rubber band ligation. Surg Gynecol Obstet. 1983;157(6):534–6.
Bullock N. Importance after sclerotherapy of haemorrhoids: case reports. BMJ. 1997;314(7078):419.
Khoury GA, Lake SP, Lewis MC, Lewis AA. A randomized trial to compare single with multiple phenol injection treatment for haemorrhoids. Br J Surg. 1985;72(9):741–2.
Senapati A, Nicholls RJ. A randomized trial to compare the results of injection sclerotherapy with a bulk laxative alone in the treatment of bleeding haemorrhoids. Int J Colorectal Dis. 1988;3(2):124–6.
Lord PH. A new regime for the treatment of haemorrhoids. Proc R Soc Med. 1968;61(9):935–6.
Speakman CT, Burnett SJ, Kamm MA, Bartram CI. Sphincter injury after anal dilatation demonstrated by anal endosonography. Br J Surg. 1991;78(12):1429–30.
MacDonald A, Smith A, McNeill AD, Finlay I. Manual dilatation of the anus. Br J Surg. 1992;79(12):1381–2.
Konsten J, Baeten CG. Hemorrhoidectomy vs Lord’s method: 17-year follow up of a prospective, randomized trial. Dis Colon Rectum. 2000;43(4):503–6.
Goligher JC. Cryosurgery for hemorrhoids. Dis Colon Rectum. 1976;19(3):213–8.
Smith LE, Goodreau JJ, Fouty WJ. Operative hemorrhoidectomy versus cryodestruction. Dis Colon Rectum. 1979;22(1):10–6.
O’Callaghan JD, Matheson TS, Hall R. Inpatient treatment of prolapsing piles:cryosurgery versus Milligan-Morgan haemorrhoidectomy. Br J Surg. 1982;69(3):157–9.
Dennison AR, Whiston RJ, Rooney S, Morris DL. The management of hemorrhoids. Am J Gastroenterol. 1989;84(5):475–81.
Bleday R, Pena JP, Rothenberger DA, Goldberg SM, Buls JG. Symptomatic hemorrhoids: current incidence and complications of operative therapy. Dis Colon Rectum. 1992;35(5):477–81.
Ferguson JA, Mazier WP, Ganchrow MI, Friend WG. The closed technique of hemorrhoidectomy. Surgery. 1971;70(3):480–4.
Read TE, Henry SE, Hovis RM, Fleshman JW, Birnbaum EH, Caushaj PF, et al. Prospective evaluation of anesthetic technique for anorectal surgery. Dis Colon Rectum. 2002;45(11):1553–8.
Lohsiriwat V, Vongjirad A, Lohsiriwat D. Value of routine histopathologic examination of three common surgical specimens: appendix, gallbladder, and hemorrhoid. World J Surg. 2009;33(10):2189–93.
Milligan ET, Morgan CN, Jones LE. Surgical anatomy of the anal canal and the operative treatment of hemorrhoids. Lancet. 1937;2:119–24.
Whitehead W. The surgical treatment of hemorrhoids. Br Med J. 1882;1:148–50.
Wolff BG, Culp CE. The Whitehead hemorrhoidectomy. An unjustly maligned procedure. Dis Colon Rectum. 1988;31(8):587–90.
Devien CV, Pujol JP. Total circular hemorrhoidectomy. Int Surg. 1989;74(3):154–7.
Boccasanta P, Venturi M, Orio A, et al. Circular hemorrhoidectomy in advanced hemorrhoidal disease. Hepatogastroenterology. 1998;45(22):969–72.
MacRae HM, Temple LK, McLeod RS. A meta-analysis for hemorrhoidal treatments. Semin C R Surg. 2002;13:77–83.
Ho YH, Seow-Choen F, Tan M, Leong AF. Randomized controlled trial of open and closed haemorrhoidectomy. Br J Surg. 1997;84(12):1729–30.
Carapeti EA, Kamm MA, McDonald PH, Chadwick SJ, Phillips RK. Randomized trial of pen versus closed day-case haemorrhoidectomy. Br J Surg. 1999;86(5):612–3.
Arbman G, Krook H, Haapaniemi S. Closed vs. open hemorrhoidectomy – is there any difference? Dis Colon Rectum. 2000;43(1):31–4.
Gencosmanoglu R, Sad O, Koc D, Inceoglu R. Hemorrhoidectomy: open or closed technique? A prospective randomized clinical trial. Dis Colon Rectum. 2002;45(1):70–5.
Ho YH, Buettner PG. Open compared with closed haemorrhoidectomy: meta-analysis of randomized controlled trials. Tech Coloproctol. 2007;11(2):135–43.
Mehigan BJ, Monson JR, Hartley JE. Stapling procedure of haemorrhoids versus Milligan-Morgan haemorrhoidectomy: randomized controlled trial. Lancet. 2000;355(9206):782–5.
Shalaby R, Desoky A. Randomized clinical trial of stapled versus Milligan-Morgan haemorrhoidectomy. Br J Surg. 2001;88(8):1049–53.
Boccasanta P, Capretti PG, Venturi M, et al. Randomised controlled trial between stapled circumferential mucosectomy and conventional circular hemorrhoidectomy in advanced hemorrhoids with external mucosal prolapse. Am J Surg. 2001;182(1):64–8.
Hetzer FH, Demartines N, Handschin AE, Clavien PA. Stapled vs excision hemorrhoidectomy: long term-results of a prospective randomized trial. Arch Surg. 2002;127(3):337–40.
Khan S, Pawlak SE, Eggenberger JC, et al. Surgical treatment of hemorrhoids: prospective, randomized trial comparing closed excisional hemorrhoidectomy and the Harmonic Scalpel technique for excisional hemorrhoidectomy. Dis Colon Rectum. 2001;44(6):845–9.
Armstrong DN, Ambroze WL, Schertzer ME, Orangio GR. Harmonic scalpel vs electrocautery hemorrhoidectomy: a prospective evaluation. Dis Colon Rectum. 2001;44(4):558–64.
Tan JJ, Seow-Choen F. Prospective, randomized trial comparing diathermy and Harmonic Scalpel hemorrhoidectomy. Dis Colon Rectum. 2001;44(5):677–9.
Franklin EJ, Seetharam S, Lowney J, Horgan PG. Randomized clinical trial of Ligasure vs conventional diathermy in hemorrhoidectomy. Dis Colon Rectum. 2003;46(10):1380–3.
Chung YC, Wu HJ. Clinical experience of sutureless closed hemorrhoidectomy with LigaSure. Dis Colon Rectum. 2003;4(1):87–92.
Chung CC, Ha JP, Tai YP, Tsang WW, Li MK. Double blind randomized trial comparing Harmonic Scalpel hemorrhoidectomy, bipolar scissors hemorrhoidectomy, and scissor excision: ligation technique. Dis Colon Rectum. 2002;45(6):789–94.
Jayne DG, Botterill I, Ambrose NS, Brennan TG, Guilou PH, O’Riordain DS. Randomized clinical trial of Ligasure versus conventional diathermy for day case haemorrhoidectomy. Dr J Surg. 2002;89(4):428–32.
Palazzo FF, Francis DL, Cligton MA. Randomized clinical trial of Ligasure versus open haemorrhoidectomy. Br J Surg. 2002;89(2):154–7.
Abo-hashem AA, Sarhan A, Aly AM. Harmonic Scalpel compared with bipolar electro-cautery hemorrhoidectomy: a randomized controlled trial. Int J Surg. 2010;8(3):243–7.
Sohn VY, Martin MJ, Mullenix PS, Cuadrado DG, Place RJ, Steele SR. A comparison of open versus closed techniques using the Harmonic Scalpel in outpatient hemorrhoid surgery. Mil Med. 2008;173(7):689–92.
Fareed M, El-Awady S, Abd-El monaem H, Aly A. Randomized trial comparing LigaSure to closed Ferguson hemorrhoidectomy. Tech Coloproctol. 2009;13(3):243–6.
Castellí J, Sueiras A, Espinosa J, Vallet J, Gil V, Pi F. Ligasure versus diathermy hemorrhoidectomy under spinal anesthesia or pudendal block with ropivacaine: a randomized prospective clinical study with 1-year follow-up. Int J Colorectal Dis. 2009;24(9):1011–8.
Tan KY, Zin T, Sim HL, Poon PL, Cheng A, Mak K. Randomized clinical trial comparing LigaSure haemorrhoidectomy with open diathermy haemorrhoidectomy. Tech Coloproctol. 2008;12(2):93–7.
Muzi MG, Milito G, Nigro C, Cadeddu F, Andreoli F, Amabile D, et al. Randomized clinical trial of LigaSure and conventional diathermy haemorrhoidectomy. Br J Surg. 2007;94(8):937–42.
Seow-Choen F, Ho YH, Ang HG, Goh HS. Prospective randomized trial comparing pain and clinical function after conventional scissors excision/ligation vs. diathermy excision without ligation for symptomatic prolapsed hemorhoides. Dis Colon Rectum. 1992;35(12):1165–9.
Andrews BT, Layer GT, Jackson BT, Nicholls RJ. Randomized trial comparing diathermy hemorrhoictomy with the scissor dissection in Milligan-Morgan operation. Dis Colon Rectum. 1993;36(6):580–3.
Ibrahim S, Tsang C, Lee YL, Eu KW, Seow-Choen F. Prospective, randomized trial comparing pain and complications between diathermy and scissors for closed hemorrhoidectomy. Dis Colon Rectum. 1998;41(11):1418–20.
Wang JY, Chang-Chien CR, Chen JS, Lai CR, Tang RP. The role of lasers in hemorrhoidectomy. Dis Colon Rectum. 1991;34(1):78–82.
Iwagaki H, Higuchi Y, Fuchimoto S, Ortia K. The laser treatment of hemorrhoids: results of a study on 1816 patients. Jpn J Surg. 1989;19(6):658–61.
Senagore A, Mazier WP, Luchtefeld MA, MacKeigan JM, Wengert T. Treatment of advanced hemorrhoidal disease: a prospective, randomized comparison of cold scalper vs contact ND:YAG laser. Dis Colon Rectum. 1993;36(11):1042–9.
Ui Y. Anoderm-preserving, completely closed hemorrhoidectomy with no mucosal incision. Dis Colon Rectum. 1997;40(10):S99–S101.
Patel N, O’Connor T. Suture haemorrhoidectomy: a day-only alternative. Aust N Z J Surg. 1996;66(12):830–1.
Mathai V, Ong BC, Ho YH. Randomized controlled trial of lateral internal sphincterotomy with haemorrhoidectomy. Br J Surg. 1996;83(3):380–2.
Carapeti EA, Kamm MA, McDonald PJ, Phillips RK. Double-blind randomized controlled trial of effect of metronidazole on pain after day-case haemorrhoidectomy. Lancet. 1998;351(9097):169–72.
Nicholson TJ, Armstron D. Topical metronidazole (10 percent) decreases posthemorrhoidectomy pain and improves healing. Dis Colon Rectum. 2004;47:711–6.
Wasvary HJ, Hain J, Mosed-Vogel M, Bendick P, Varkel DC, Klein SN. Randomized, prospective, double-blind, placebo controlled trial of effect of nitroglycerin ointment on pain after hemorrhoidectomy. Dis Colon Rectum. 2001;44(8):1069–73.
Karanlik H, Akturk R, Camlica H, Asoglu O. The effect of glyceryl trinitrate ointment on posthemorrhoidectomy pain and wound healing: results of a randomized, double-blind, placebo-controlled study. Dis Colon Rectum. 2009;52(2):280–5.
Hussein MK, Taha AM, Haddad FF, Bassim YR. Bupivacaine local injection in anorectal surgery. Int Surg. 1009;83(1):56–7.
Pryn SJ, Crosse MM, Murison MS, McGinn FP. Postoperative analgesia for haemorrhoidectomy. A comparison between caudal and local infiltration. Anaesthesia. 1989;44(12):964–6.
Chester JF, Standford BJ, Gazet JC. Analgesia benefit of locally injected bupivacaine after hemorrhoidectomy. Dis Colon Rectum. 1990;33(6):487–9.
Ho YH, Seow-Choen F, Low JY, Tn M, Leong AP. Randomized controlled trial of trimebutine (anal sphincter relaxant) for pain after haemorrhoidectomy. Br J Surg. 1997;84(3):377–9.
Gottesman L, Milsom JW, Mazier WP. The use of anxiolytic and parasympathomimetic agents in the treatment of postoperative urinary retention following anorectal surgery. A prospective, randomized, double-blind study. Dis Colon Rectum. 1989;32(10):687–870.
Cataldo PA, MacKeigan JM. The necessity of routine pathologic evaluation of hemorrhoidectomy specimens. Surg Gynecol Obstet. 1992;174(4):302–4.
Rosen L, Sipe P, Stasik JJ, et al. Outcome of delayed hemorrhage following surgical hemorrhoidectomy (letter). Dis Colon Rectum. 1994;37:288–9.
Basso L, Pescatroi M. Outcome of delayed hemorrhoids following surgical hemorrhoidectomy (letter). Dis Colon Rectum. 1994;37:288–9.
Chen HH, Wang JY, Changchien RC, et al. Risk factors associated with post-hemorrhoidectomy secondary hemorrhoidage. A single institution prospective study of 4880 consecutive hemorrhoidectomies. Dis Colon Rectum. 2003;45:1096–9.
Chen HH, Wang J, Changchien CR, Yeh CY, Tsai WS, Tang R. Effective management of posthemorrhoidectomy secondary hemorrhage using rectal irrigation. Dis Colon Rectum. 2002;45:234–8.
Tajana A. Hemorrhoidectomy according to Milligan-Morgan: ligature and excision technique. Int Surg. 1989;74(3):158–61.
Johnstone CS, Isbisteer WH. Inpatient management of pile: a surgical audit. Aust N Z J Surg. 1992;62(9):720–4.
Eu KW, Seow-Choen F, Goh HS. Comparison of emergency and elective haemorrhoidectomy. Br J Surg. 1994;81(2):308–10.
Ganchrow MI, Mazier WP, Friend WG, Ferguson JA. Hemorrhoidectomy revisited: a computer analysis of 2038 cases. Dis Colon Rectum. 1971;14:128–33.
Goldberg SM, Gordon PH, Nivatvongs S. Hemorrhoids. In: Essentials of Anorectal Surgery. Philadelphia: Lippincott, 1980.
McConnell JC, Khubchandani IT. Long term follow up of closed haemorrhoidectomy. Dis Colon Rectum. 1983;26:797–9.
Pescatori M, Favetta U, Dedola S, Orsini S. Transanal stapled excision for rectal mucosal prolapse. Tech Coloproctol. 1997;1:96–8.
Longo A. Treatment of hemorrhoidal disease by reduction for mucosa and haemorrhoidal prolapse with a circular stapling device: a new procedure – 6th World Congress of Endoscopic Surgery. Mundozzi Editore 1998; 777–84.
Ho YH, Cheong WK, Tsang C, et al. Stapled hemorrhoidectomy cost and effectiveness. Randomized, controlled trial including incontinence scoring, anorectal manometry, and endoanal ultrasound assessments at up to three months. Dis Colon Rectum. 2000;43(12):1666–75.
Brown SR, Ballan K, Ho E, et al. Stapled mucosectomy for acute thrombosed circumferentially prolapsed piles: a prospective randomized comparison with conventional haemorrhoidectomy. Colorectal Dis. 2001;3(3):175–8.
Hetzer FH, Demartines N, Handschin AE, et al. Stapled vs excision hemorrhoidectomy: long-term results of a prospective randomized trial. Arch Surg. 2002;137(3):337–40.
Ortiz H, Marzo J, Armendariz P. Randomized clinical trial of stapled haemorrhoidopexy versus conventional diathermy haemorrhoidectomy. Br J Surg. 2002;89(11):1376–81.
Pavlidis T, Papaziogas B, Souparis A, et al. Modern stapled Longo procedure vs. conventional Milligan-Morgan hemorrhoidectomy: a randomized controlled trial. Int J Colorectal Dis. 2002;17(1):50–3.
Palimento D, Picchio M, Attanasio U, et al. Stapled and open hemorrhoidectomy: randomized controlled trial of early results. World J Surg. 2003;27(2):203–7.
Kraemer M, Parulava T, Roblick M, et al. Prospective, randomized study: proximate PPH stapler vs. LigaSure for hemorrhoidal surgery. Dis Colon Rectum. 2005;48(8):1517–22.
Correa-Rovelo JM, Tellez O, Obregon L, et al. Stapled rectal mucosectomy vs. closed hemorrhoidectomy: a randomized clinical trial. Dis Colon Rectum. 2002;45(10):1367–74 [discussion:1374–5].
Wilson MS, Pope V, Doran HE, et al. Objective comparison of stapled anopexy and open hemorrhoidectomy: a randomized, controlled trial. Dis Colon Rectum. 2002;45(11):1437–44.
Rowsell M, Bello M, Hemingway DM. Circumferential mucosectomy (stapled haemorrhoidectomy) versus conventional haemorrhoidectomy: randomised controlled trial. Lancet. 2000;355(9206):779–81.
Cheetham MJ, Cohen CR, Kamm MA, et al. A randomized controlled trial of diathermy hemorrhoidectomy vs. stapled hemorrhoidectomy in an intended day-care setting with longer-term follow-up. Dis Colon Rectum. 2003;46(4):491–7.
Bikhchandani J, Agarwal PN, Kant R, et al. Randomized controlled trial to compare the early and mid-term results of stapled versus open hemorrhoidectomy. Am J Surg. 2005;189(1):56–60.
Kairaluoma M, Nuorva K, Kellokumpu I. Day-case stapled (circular) vs. diathermy hemorrhoidectomy: a randomized, controlled trial evaluating surgical and functional outcome. Dis Colon Rectum. 2003;46(1):93–9.
Gravie JF, Lehur PA, Huten N, et al. Stapled hemorrhoidopexy versus Milligan-Morgan hemorrhoidectomy: a prospective, randomized, multicenter trial with 2-year postoperative follow up. Ann Surg. 2005;242(1):29–35.
Chung CC, Cheung HY, Chan ES, et al. Stapled hemorrhoidopexy vs. Harmonic Scalpel hemorrhoidectomy: a randomized trial. Dis Colon Rectum. 2005;48(6):1213–9.
Ortiz H, Marzo J, Armendariz P, et al. Stapled hemorrhoidopexy vs. diathermy excision for fourth-degree hemorrhoids: a randomized, clinical trial and review of the literature. Dis Colon Rectum. 2005;48(4):809–15.
Ganio E, Altomare DF, Gabrielli F, et al. Prospective randomized multicentre trial comparing stapled with open haemorrhoidectomy. Br J Surg. 2001;88(5):669–74.
Smyth EF, Baker RP, Wilken BJ, et al. Stapled versus excision haemorrhoidectomy: long term follow up of a randomised controlled trial. Lancet. 2003;361(9367):1437–8.
Racalbuto A, Aliotta I, Corsaro G, et al. Hemorrhoidal stapler prolapsectomy vs. Milligan-Morgan hemorrhoidectomy: a long-term randomized trial. Int J Colorectal Dis. 2004;19(3):239–44.
Krska Z, Kvasnieka J, Faltyn J, et al. Surgical treatment of haemorrhoids according to Longo and Milligan Morgan: an evaluation of postoperative tissue response. Colorectal Dis. 2003;5(6):573–6.
Nisar PJ, Acheson AG, Neal KR, et al. Stapled hemorrhoidopexy compared with conventional hemorrhoidectomy: systematic review of randomized, controlled trials. Dis Colon Rectum. 2004;47(11):1837–45.
Lan P, Wu X, Zhou X, et al. The safety and efficacy of stapled hemorrhoidectomy in the treatment of hemorrhoids: a systematic review and meta-analysis of ten randomized control trials. Int J Colorectal Dis. 2006;21(2):172–8.
Shao WJ, Li GCH, Zhang ZHK, Yang BL, Sun GD, Chen YQ. Systematic review and meta-analysis of randomized controlled trials comparing stapled haemorrhoideopexy with conventional haemorrhoidectomy. Br J Surg. 2008;95:147–60.
Cipriani S, Pescatori M. Acute rectal obstruction after PPH stapled haemorrhoidectomy. Colorectal Dis. 2002;4(5):367–70.
Wong LY, Jiang JK, Chang SC, et al. Rectal perforation: a life-threatening complication of stapled hemorrhoidectomy: report of a case. Dis Colon Rectum. 2003;46(1):116–7.
Maw A, Eu KW, Seow-Choen F. Retroperitoneal sepsis complicating stapled hemorrhoidectomy: report of a case and review of the literature. Dis Colon Rectum. 2002;45(6):826–8.
Molloy RG, Kingsmore D. Life threatening pelvic sepsis after stapled haemorrhoidectomy. Lancet. 2000;355(9206):810.
Ripetti V, Caricato M, Arullani A. Rectal perforation, retropneumoperitoneum, and pneumomediastinum after stapling procedure for prolapsed hemorrhoids: report of a case and subsequent considerations. Dis Colon Rectum. 2002;45(2):268–70.
Ho YH, Seow-Cheen F, Tsang C, Eu KW. Randomized trial assessing anal sphincter injuries after stapled haemorrhoidectomy. Br J Surg. 2001;88(11):1449–55.
George BD, Shetty D, Lindsey I, Mortensen NJ, Warren BF. Histopathology of stapled haemorrhoidectomy specimens: a cautionary note. Colorectal Dis. 2002;4(6):473–6.
Roos P. Haemorrhoid surgery revised. Lancet. 2000;355(9215):1648.
Pescatori M. Prospective randomized multicentre trial comparing stapled with open haemorrhoidectomy. Br J Surg. 2002;89(1):122.
Morinaga K, Hasuda K, Ikeda T. A novel therapy for internal hemorrhoids: ligation of the hemorrhoidal artery with a newly devised instrument (Moricorn) in conjunction with a Doppler flowmeter. Am J Gastroenterol. 1995;90(4):610–3.
Dal Monte PP, Tagariello C, Giordano P, Cudazzo E, Shafi A, Sarago M, Franzini M. Transanal haemorrhoidal dearterialisation:nonexcisional surgery for heat treatment of haemorrhoidal disease. Tech Coloproctol 2007;11(4):333–9.
Charua Guindic L, Fonseca Munoz E, García Perez NJ, et al. Hemorrhoidal dearterialization guided by Doppler. A surgical alternative in hemorrhoidal disease management. Rev Gastroenterol Méx. 2004;69:83–7.
Bursics A, Morvay K, Kupcsulik P, Flautner L. Comparison of early and 1-year follow-up results of conventional hemorrhoidectomy and hemorrhoid artery ligation: a randomized study. Int J Colorectal Dis. 2004;19:176–80.
Ramirez JM, Gracia JA, Aguilella V, Elia M, Casamayor MC, Martinez M. Surgical management of symptomatic haemorrhoids: to cut, to hang or to strangle? A prospective randomized controlled trial. Colorectal Dis. 2005;7:52.
Ramirez JM, Aguilella V, Elía M, Gracia JA, Martínez M. Doppler-guided hemorrhoidal artery ligation in the management of symptomatic hemorrhoids. Rev Esp Enferm Dig. 2005;97:97–103.
Felice G, Privitera A, Ellul E, Klaumann M. Doppler-guided hemorrhoidal artery ligation: an alternative to hemorrhoidectomy. Dis Colon Rectum. 2005;48:2090–3.
Greenberg R, Karin E, Avital S, Skornick Y, Werbin N. First 100 cases with Doppler-guided hemorrhoidal artery ligation. Dis Colon Rectum. 2006;49:485–9.
de Vries BM Wallis, van der Beek ES, de Wijkerslooth LR, et al. Treatment of grade 2 and 3 hemorrhoids with Doppler-guided hemorrhoidal artery ligation. Dig Surg. 2007;24:436–40.
Abdeldaim Y, Mabadeje O, Muhammad KM, Mc Avinchey D. Doppler-guided haemorrhoidal arteries ligation: preliminary clinical experience. Ir Med J. 2007;100:535–7.
Giordano P, Overton J, Madeddu F, Zaman S, Gravante G. Transanal hemorrhoidal de-arterialization: A systematic review. Dis Colon Rectum. 2009;52:1665–71.
Rasmussen OO, Larsen KG, Naver L, Christiansen J. Emergency haemorrhoidectomy compared with incision and banding for the treatment of acute strangulated haemorrhoids. A prospective randomised study. Eur J Surg. 1991;157(10):613–4.
McCormack TT, Bailey HR, Simms JM, Johnson AG. Rectal varices are not piles. Br J Surg. 1984;71:163.
Bernstein WC. What are hemorrhoids and what is their relationship to the portal venous system? Dis Colon Rectum. 1983;23(12):829–34.
Hosking SW, Smart HL, Johnson AG, Triger DR. Anorectal varices, haemorrhoids, and portal hypertension. Lancet. 1989;1(8624):349–52.
Goenka MK, Kochhar R, Nagi B, Mehta SK. Rectosigmoid varices and other mucosal changes in patients with portal hypertension. Am J Gastroenterol. 1991;86(9):1185–9.
Chawla Y, Dilawari JB. Anorectal varices – their frequency in cirrhotic and non-cirrhotic portal hypertension. Gut. 1991;32(3):309–11.
Johansen K, Bardin J, Orloff MJ. Massive bleeding from hemorrhoidal varices in portal hypertension. JAMA. 1980;244(18):2084–5.
Hosking SW, Johnson AG. Bleeding anorectal varices – a misunderstood condition. Surgery. 1988;104(1):70–3.
George BS, ML LAJ. Stapled anopexy in the treatment of anal varices: report of a case. Dis Colon Rectum. 2003;46(9):1284–5.
Shibata D, Brophy DP, Gordon FD, Anastopoulos HT, Sentovich SM, Bleday R. Transjugular intrahepatic portosystemic shunt for treatment of bleeding ectopic varices with portoal hypertension. Dis Colon Rectum. 1999;42(12):1581–5.
Fantin AC, Zala G, Risti B, Debatin JF, Schopke W, Meyenberger C. Bleeding anorectal varices: successful treatment with transjugular intrahepatic portosystemic shuntin (TIPS). Gut. 1996;38(6):932–5.
Montemurro S, Polignano FM, Caliandro C, Rucci A, Ruggieri E, Sciscio V. Inferior mesocaval shunt for bleeding anorectal varices and portal vein thrombosis. Hepatogastroenterology. 2001;48(40):980–3.
Rahmani O, Wolpert LM, Drezner AD. Distal inferior mesenteric veins to renal vein shunt for treatment of bleeding anorectal varices: case report and review of literature. J Vasc Surg. 2002;36(6):1264–6.
Saleeby Jr RG, Rosen L, Stasik JJ, Tiether Rd, Sheets J, Khubchandani IT. Hemorrhoidectomy during pregnancy: risk or relief? Dis Colon Rectum. 1991;34(3):260–1.
Jeffery PJ, Parks AG, Ritchie JK. Treatment of haemorrhoids in patients with inflammatory bowel disease. Lancet. 1977;1(8021):1084–5.
Wolkomir AF, Luchtefeld MA. Surgery for symptomatic hemorrhoids and anal fissures in Crohn’s disease. Dis Colon Rectum. 1993;36(6):545–7.
Grewal H, Guillem JG, Quan SH, Enker WE, Cohen AM. Anorectal disease in neutropenic leukemic patients. Operative vs nonoperative management. Dis Colon Rectum. 1994;37(11):1095–9.
Morandi E, Merlini D, Salvaggio A, Foschi D, Trabucci E. Prospective study of healing time after hemorrhoidectomy: influence of HIV infection, acquired immunodeficiency syndrome, and anal wound infection. Dis Colon Rectum. 1999;42(9):1140–4.
Acknowledgment.
This chapter was written by Jose R. Citron and Herand Abcarian in the first edition of this textbook.
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Singer, M. (2011). Hemorrhoids. In: Beck, D.E., Roberts, P.L., Saclarides, T.J., Senagore, A.J., Stamos, M.J., Wexner, S.D. (eds) The ASCRS Textbook of Colon and Rectal Surgery. Springer, New York, NY. https://doi.org/10.1007/978-1-4419-1584-9_11
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