Disruption of cholangiocyte-B cell crosstalk by blocking the CXCL12-CXCR4 axis alleviates liver fibrosis Linhao ZhangChong ZhaoJinhang Gao Original Article 27 November 2023 Article: 379
Mistranslation-associated perturbations of proteostasis do not promote accumulation of amyloid beta and plaque deposition in aged mouse brain Harshitha Santhosh KumarJames MooreErik C. Böttger Original Article Open access 27 November 2023 Article: 378
The secreted peptide BATSP1 promotes thermogenesis in adipocytes Xianwei CuiHong ZhongChenbo Ji Original Article Open access 27 November 2023 Article: 377
Molecular modeling of apoE in complexes with Alzheimer’s amyloid-β fibrils from human brain suggests a structural basis for apolipoprotein co-deposition with amyloids Emily LewkowiczMari N. NakamuraOlga Gursky Original Article 27 November 2023 Article: 376
Interleukin 4 improved adipose-derived stem cells engraftment via interacting with fibro/adipogenic progenitors in dystrophic mice Huan LiJinfu LinCheng Zhang Original Article Open access 27 November 2023 Article: 375
E3-ubiquitin ligase, FBXW7 regulates mitotic progression by targeting BubR1 for ubiquitin-mediated degradation Vishnu M. NairAmit Santhu SabuTapas K. Manna Original Article 26 November 2023 Article: 374
Combined RNA interference and gene replacement therapy targeting MFN2 as proof of principle for the treatment of Charcot–Marie–Tooth type 2A Federica RizzoSilvia BonoStefania Corti Original Article Open access 25 November 2023 Article: 373
Cordycepin delays postovulatory aging of oocytes through inhibition of maternal mRNAs degradation via DCP1A polyadenylation suppression Chong LiLing ZhuJing-Yu Li Original Article Open access 25 November 2023 Article: 372
Recombinant protein delivery enables modulation of the phototransduction cascade in mouse retina Sabrina AsteritiValerio MarinoDaniele Dell’Orco Original Article Open access 25 November 2023 Article: 371
Exploring the link between hedonic overeating and prefrontal cortex dysfunction in the Ts65Dn trisomic mouse model Marta FructuosoÁlvaro Fernández-BlancoMara Dierssen Original Article 21 November 2023 Article: 370
BK channels sustain neuronal Ca2+ oscillations to support hippocampal long-term potentiation and memory formation Thomas PhamTamara HusseinLucas Matt Original Article Open access 21 November 2023 Article: 369
STIM2 regulates NMDA receptor endocytosis that is induced by short-term NMDA receptor overactivation in cortical neurons Karolina SerwachEwa NurowskaJoanna Gruszczynska-Biegala Original Article Open access 21 November 2023 Article: 368
Thalamic Foxp2 regulates output connectivity and sensory-motor impairments in a model of Huntington’s Disease Ened Rodríguez-UrgellésDiana Casas-TorremochaJordi Alberch Original Article Open access 21 November 2023 Article: 367
Unraveling the lymphatic system in the spinal cord meninges: a critical element in protecting the central nervous system Sriharsha GonuguntlaJasmin Herz Review 20 November 2023 Article: 366
Unconventional roles of chromatin remodelers and long non-coding RNAs in cell division Yuri ProzzilloMaria Virginia SantopietroPatrizio Dimitri Review Open access 20 November 2023 Article: 365
SARS-CoV-2 ORF6 protein targets TRIM25 for proteasomal degradation to diminish K63-linked RIG-I ubiquitination and type-I interferon induction Oyahida KhatunMansi SharmaShashank Tripathi Original Article 20 November 2023 Article: 364
Polymorphic USP8 allele promotes Parkinson’s disease by inducing the accumulation of α-synuclein through deubiquitination Shouhai WuTongxiang LinYang Xu Original Article 19 November 2023 Article: 363
Molecular basis of retinal remodeling in a zebrafish model of retinitis pigmentosa Abirami SanthanamEyad ShihabeddinJohn O’Brien Original Article Open access 18 November 2023 Article: 362
GTPBP8 is required for mitoribosomal biogenesis and mitochondrial translation Liang WangTaru HilanderHongxia Zhao Original Article Open access 16 November 2023 Article: 361
Protein aggregates act as a deterministic disruptor during bacterial cell size homeostasis Julien MortierSander K. GoversAbram Aertsen Original Article 16 November 2023 Article: 360
miR-455-5p promotes pathological cardiac remodeling via suppression of PRMT1-mediated Notch signaling pathway Sidong CaiJunlei ChangKai-Hang Yiu Original Article Open access 11 November 2023 Article: 359
TFEB SUMOylation in macrophages accelerates atherosclerosis by promoting the formation of foam cells through inhibiting lysosomal activity Kezhou WangWei ZhouTian Tian Original Article 11 November 2023 Article: 358
MiR-326-mediated overexpression of NFIB offsets TGF-β induced epithelial to mesenchymal transition and reverses lung fibrosis Bijay PattnaikVinny NegiTanveer Ahmad Original Article 11 November 2023 Article: 357
Low glycemic index diet restrains epileptogenesis in a gender-specific fashion Caterina MichettiDaniele FerrantePietro Baldelli Original Article Open access 10 November 2023 Article: 356
Emerging roles and mechanisms of ERK pathway mechanosensing Flora CrozetRomain Levayer Review Open access 10 November 2023 Article: 355
Measuring neuron-regulated immune cell physiology via the alpha-2 adrenergic receptor in an ex vivo murine spleen model Alexandra K. BrookeDaniel P. MurrowAshley E. Ross Original Article 09 November 2023 Article: 354
The KxGxYR and DxE motifs in the C-tail of the Middle East respiratory syndrome coronavirus membrane protein are crucial for infectious virus assembly Lowiese DesmaretsAdeline DanneelsSandrine Belouzard Original Article Open access 09 November 2023 Article: 353
Insights into the structure and function of the RNA ligase RtcB Matthieu MoncanHassan Rakhsh-KhorshidAdrienne M. Gorman Review Open access 07 November 2023 Article: 352
Amyloid-β mediates intestinal dysfunction and enteric neurons loss in Alzheimer's disease transgenic mouse Guoqiang LiuQuntao YuHao Li Original Article 06 November 2023 Article: 351
Exploring the therapeutic potential of ADC combination for triple-negative breast cancer Linlin LuZihe NiuYaqin Shi Review 06 November 2023 Article: 350
The proper timing of Atoh1 expression is pivotal for hair cell subtype differentiation and the establishment of inner ear function Dan YouWenli NiWenyan Li Original Article Open access 06 November 2023 Article: 349
Correction: Chromogranin A and its derived peptides: potential regulators of cholesterol homeostasis Dhanya R. IyerJanani VenkatramanNitish R. Mahapatra Correction 06 November 2023 Article: 348
Tubular TMEM16A promotes tubulointerstitial fibrosis by suppressing PGC-1α-mediated mitochondrial homeostasis in diabetic kidney disease Jia-Ling JiJun-Ying LiZuo-Lin Li Original Article 06 November 2023 Article: 347
