1. Delivered Dose: A Drug-centric Phenotype for Chemotherapy Dose Individualization

   • Y. Bruce Yu

   Commentary 03 June 2009 Pages: 1803 - 1806

   

2. Elucidating the ‘Jekyll and Hyde’ Nature of PXR: The Case for Discovering Antagonists or Allosteric Antagonists

   • Arunima Biswas
   • Sridhar Mani
   • Sean Ekins

   Expert Review 05 May 2009 Pages: 1807 - 1815

   

3. Identification of Novel Specific and General Inhibitors of the Three Major Human ATP-Binding Cassette Transporters P-gp, BCRP and MRP2 Among Registered Drugs

   • Pär Matsson
   • Jenny M. Pedersen
   • Per Artursson

   Research Paper 07 May 2009 Pages: 1816 - 1831

   

4. Effect of Co-administration of Tacrolimus on the Pharmacokinetics of Multiple Subcutaneous Administered Interferon-Alpha in Rats

   • Hiroyuki Yamazaki
   • Masateru Miyake
   • Hiroshi Kiwada

   Research Paper 05 May 2009 Pages: 1832 - 1837

   

5. Local Controlled Delivery of Anti-Neoplastic RNAse to the Brain

   • Joram Slager
   • Betty Tyler
   • Henry Brem

   Research Paper 05 May 2009 Pages: 1838 - 1846

   

6. Formulation and Pharmacokinetics of Self-Assembled Rifampicin Nanoparticle Systems for Pulmonary Delivery

   • Jean C. Sung
   • Danielle J. Padilla
   • David A. Edwards

   Research Paper 30 April 2009 Pages: 1847 - 1855

   

7. Development of Multi-Phase Emulsions Based on Bioresorbable Polymers and Oily Adjuvant

   • Ming-Hsi Huang
   • Chiung-Yi Huang
   • Pele Chong

   Research Paper 05 May 2009 Pages: 1856 - 1862

   

8. Mechanism-Based Pharmacokinetic–Pharmacodynamic Modeling of Bidirectional Effect of Danshensu on Plasma Homocysteine in Rats

   • Yuancheng Chen
   • Yanguang Cao
   • Xiaoquan Liu

   Research Paper 07 May 2009 Pages: 1863 - 1873

   

9. New Difluoro Knoevenagel Condensates of Curcumin, Their Schiff Bases and Copper Complexes as Proteasome Inhibitors and Apoptosis Inducers in Cancer Cells

   • Subhash Padhye
   • Huanjie Yang
   • Fazlul H. Sarkar

   Research Paper 07 May 2009 Pages: 1874 - 1880

   

10. Prediction of Human Bioavailability from Human Oral Administration Data and Animal Pharmacokinetic Data Without Data from Intravenous Administration of Drugs in Humans

    • Haruo Imawaka
    • Kiyomi Ito
    • Yuichi Sugiyama

    Research Paper 07 May 2009 Pages: 1881 - 1889

    

11. Novel Inhibitors of Human Organic Cation/Carnitine Transporter (hOCTN2) via Computational Modeling and In Vitro Testing

    • Lei Diao
    • Sean Ekins
    • James E. Polli

    Research Paper 13 May 2009 Pages: 1890 - 1900

    

12. In Vitro Gastrointestinal Lipolysis of Four Formulations of Piroxicam and Cinnarizine with the Self Emulsifying Excipients Labrasol® and Gelucire® 44/14

    • Sylvie Fernandez
    • Stéphanie Chevrier
    • Vincent Jannin

    Research Paper 19 May 2009 Pages: 1901 - 1910

    

13. A New Minimal-Stress Freely-Moving Rat Model for Preclinical Studies on Intranasal Administration of CNS Drugs

    • Jasper Stevens
    • Ernst Suidgeest
    • Elizabeth C. M. de Lange

    Research Paper Open access 19 May 2009 Pages: 1911 - 1917

    

14. Chitosan/TPP and Chitosan/TPP-hyaluronic Acid Nanoparticles: Systematic Optimisation of the Preparative Process and Preliminary Biological Evaluation

    • Alessandro Nasti
    • Noha M. Zaki
    • Nicola Tirelli

    Research Paper 09 June 2009 Pages: 1918 - 1930

    

15. A Potential Targeting Gene Vector Based on Biotinylated Polyethyleneimine/Avidin Bioconjugates

    • Xuan Zeng
    • Yun-Xia Sun
    • Ren-Xi Zhuo

    Research Paper 05 June 2009 Pages: 1931 - 1941

    

16. Integration of Preclinical and Clinical Data with Pharmacokinetic Modeling and Simulation to Evaluate Fexofenadine as a Probe for Hepatobiliary Transport Function

    • Brandon Swift
    • Xianbin Tian
    • Kim L. R. Brouwer

    Research Paper 04 June 2009 Pages: 1942 - 1951

    

17. Semi-Mechanistic Model for Neutropenia after High Dose of Chemotherapy in Breast Cancer Patients

    • Amelia Ramon-Lopez
    • Ricardo Nalda-Molina
    • Juan Jose Perez-Ruixo

    Research Paper 02 June 2009 Pages: 1952 - 1962

    

18. The In vitro Sub-cellular Localization and In vivo Efficacy of Novel Chitosan/GMO Nanostructures containing Paclitaxel

    • W.J. Trickler
    • A.A. Nagvekar
    • A.K. Dash

    Research Paper 20 May 2009 Pages: 1963 - 1973

    

19. Skin Solubility Determines Maximum Transepidermal Flux for Similar Size Molecules

    • Qian Zhang
    • Jeffrey E. Grice
    • Michael S. Roberts

    Research Paper 05 June 2009 Pages: 1974 - 1985

    

20. Inhibition of Peptide Acylation in PLGA Microspheres with Water-soluble Divalent Cationic Salts

    • Ying Zhang
    • Andreas M. Sophocleous
    • Steven P. Schwendeman

    Research Paper 16 June 2009 Pages: 1986 - 1994

    

21. Drug Delivery to the Skin From Sub-micron Polymeric Particle Formulations: Influence of Particle Size and Polymer Hydrophobicity

    • Xiao Wu
    • Bruno Biatry
    • Richard H. Guy

    Research Paper 10 June 2009 Pages: 1995 - 2001

    

22. Composite Hydrogel Formulations of Stratifin to Control MMP-1 Expression in Dermal Fibroblasts

    • Elham Rahmani-Neishaboor
    • John Jackson
    • Aziz Ghahary

    Research Paper 17 June 2009 Pages: 2002 - 2014

    

23. Role of Salt and Excipient Properties on Disproportionation in the Solid-State

    • Peter Guerrieri
    • Lynne S. Taylor

    Research Paper 09 June 2009 Pages: 2015 - 2026

    

24. Investigation of Polylactic Acid (PLA) Nanoparticles as Drug Delivery Systems for Local Dermatotherapy

    • Fiorenza Rancan
    • Dimitrios Papakostas
    • Annika Vogt

    Research Paper 17 June 2009 Pages: 2027 - 2036

    

25. News

    News 06 June 2009 Pages: 2037 - 2038