1. An overview of the orexinergic system in different animal species

   • Idris A. Azeez
   • Olumayowa O. Igado
   • James O. Olopade

   Review Article 05 July 2021 Pages: 1419 - 1444

   

2. How cytosolic compartments play safeguard functions against neuroinflammation and cell death in cerebral ischemia

   • Fari Ryan
   • Seyed Esmaeil Khoshnam
   • Abolhassan Ahmadiani

   Review Article 26 June 2021 Pages: 1445 - 1467

   

3. The potential role of Keap1-Nrf2 pathway in the pathogenesis of Alzheimer’s disease, type 2 diabetes, and type 2 diabetes-related Alzheimer’s disease

   • Ling He
   • Yi Sun

   Review Article 15 June 2021 Pages: 1469 - 1479

   

4. Therapeutic approaches employing natural compounds and derivatives for treating bipolar disorder: emphasis on experimental models of the manic phase

   • Vânia Machado Recart
   • Luiza Spohr
   • Roselia Maria Spanevello

   Review Article 15 July 2021 Pages: 1481 - 1499

   

5. Flavonoids modulate AMPK/PGC-1α and interconnected pathways toward potential neuroprotective activities

   • Mohammad Mehdi Gravandi
   • Sajad Fakhri
   • Haroon Khan

   Review Article 14 May 2021 Pages: 1501 - 1521

   

6. Association between thyroid function and Alzheimer's disease: A systematic review

   • Paulina Belén Sepulveda Figueroa
   • Ana Flávia Fernandes Ferreira
   • Andréa da Silva Torrão

   Review Article 19 June 2021 Pages: 1523 - 1543

   

7. Gut brain axis: an insight into microbiota role in Parkinson’s disease

   • Sara Ayman Moustafa
   • Shrouk Mohamed
   • Mohamed Salama

   Review Article 09 August 2021 Pages: 1545 - 1557

   

8. Effects of physical exercise on memory in type 2 diabetes: a brief review

   • Ricardo Augusto Leoni De Sousa
   • Alex Cleber Improta-Caria
   • Ricardo Cardoso Cassilhas

   Review Article 11 June 2021 Pages: 1559 - 1563

   

9. Adiponectin: a potential target for obesity-associated Alzheimer’s disease

   • Nikita Patil Samant
   • Girdhari Lal Gupta

   Review Article 28 May 2021 Pages: 1565 - 1572

   

10. PTZ kindling model for epileptogenesis, refractory epilepsy, and associated comorbidities: relevance and reliability

    • Tanveer Singh
    • Awanish Mishra
    • Rajesh Kumar Goel

    Review Article 24 August 2021 Pages: 1573 - 1590

11. Neuroinflammation in neurological disorders: pharmacotherapeutic targets from bench to bedside

    • Awanish Mishra
    • Ritam Bandopadhyay
    • Navneet Khurana

    Review Article 13 August 2021 Pages: 1591 - 1626

    

12. Role of metals in Alzheimer’s disease

    • Nikita Das
    • James Raymick
    • Sumit Sarkar

    Review Article 27 July 2021 Pages: 1627 - 1639

    

13. Profiles of urine and blood metabolomics in autism spectrum disorders

    • Narueporn Likhitweerawong
    • Chanisa Thonusin
    • Siriporn C. Chattipakorn

    Review Article 02 August 2021 Pages: 1641 - 1671

    

14. Experimental evidence of tyrosine neurotoxicity: focus on mitochondrial dysfunction

    • Jade de Oliveira
    • Hémelin Resende Farias
    • Emilio Luiz Streck

    Review Article 02 July 2021 Pages: 1673 - 1685

    

15. Mesenchymal stem cell therapies for Alzheimer’s disease: preclinical studies

    • Xiaorong Zhao
    • Dandan Li
    • Bo Niu

    Review Article 02 July 2021 Pages: 1687 - 1695

    

16. Knowledge about the characteristics of stroke-like lesions is expandable

    • Josef Finsterer

    Commentary 26 August 2021 Pages: 1697 - 1698

17. Withania coagulans extract attenuates oxidative stress-mediated apoptosis of cerebellar purkinje neurons after ischemia/reperfusion injury

    • Zahra Heidari
    • Hamidreza Mahmoudzadeh-Sagheb
    • Enam Alhagh Charkhat Gorgich

    Original Article 10 May 2021 Pages: 1699 - 1708

    

18. Pain-relieving effects of Lawsonia inermis on neuropathic pain induced by chronic constriction injury

    • Hassan Rakhshandeh
    • Amirhosein Ghorbanzadeh
    • Fatemeh Forouzanfar

    Original Article 25 June 2021 Pages: 1709 - 1716

    

19. Palatable high-fat diet intake influences mnemonic and emotional aspects in female rats in an estrous cycle-dependent manner

    • Sara Pereira Silva
    • José Ivo Araújo Beserra-Filho
    • Alessandra Mussi Ribeiro

    Original Article 18 August 2021 Pages: 1717 - 1727

    

20. Alpha lipoic acid ameliorates scopolamine induced memory deficit and neurodegeneration in the cerebello-hippocampal cortex

    • Adejoke Elizabeth Memudu
    • Abosede Esther Adewumi

    Original Article 22 May 2021 Pages: 1729 - 1745

    

21. Carotid intima media thickness measurements coupled with stroke severity strongly predict short-term outcome in patients with acute ischemic stroke: a machine learning study

    • Ana Lucia Cruz Fürstenberger Lehmann
    • Daniela Frizon Alfieri
    • Edna Maria Vissoci Reiche

    Original Article 04 August 2021 Pages: 1747 - 1761

    

22. A network pharmacology study with molecular docking to investigate the possibility of licorice against posttraumatic stress disorder

    • Zhi-Kun Qiu
    • Zhi-Ting Liu
    • Ji-Sheng Chen

    Original Article 21 August 2021 Pages: 1763 - 1777

    

23. Icariin enhance mild hypothermia-induced neuroprotection via inhibiting the activation of NF-κB in experimental ischemic stroke

    • Mingming Dai
    • Bin Chen
    • Hang Yu

    Original Article 12 May 2021 Pages: 1779 - 1790

    

24. The effect of Crocin on TFAM and PGC-1α expression and Catalase and Superoxide dismutase activities following cholestasis-induced neuroinflammation in the striatum of male Wistar rats

    • Mohammad-Reza Eteghadi
    • Mohammad Nasehi
    • Saeed Hesami-Tackallou

    Original Article 21 May 2021 Pages: 1791 - 1801

    

25. Alzheimer’s disease: a step closer to understanding type 3 diabetes in African Americans

    • Sherry A. Ferguson
    • John J. Panos
    • Sumit Sarkar

    Original Article 22 May 2021 Pages: 1803 - 1816

26. Therapeutic hypothermia augments the restorative effects of PKC-β and Nox2 inhibition on an in vitro model of human blood–brain barrier

    • Rais Reskiawan A. Kadir
    • Mansour Alwjwaj
    • Ulvi Bayraktutan

    Original Article Open access 16 August 2021 Pages: 1817 - 1832

    

27. Exploring nordihydroguaretic acid (NDGA) as a plausible neurotherapeutic in the experimental paradigm of autism spectrum disorders targeting nitric oxide pathway

    • Rishab Mehta
    • Ranjana Bhandari
    • Anurag Kuhad

    Original Article 07 August 2021 Pages: 1833 - 1857

    

28. Amygdalus spinosissima root extract enhanced scopolamine-induced learning and memory impairment in mice

    • Maryam Sajjadi
    • Ehsan Oskoueian
    • Mahdi Ebrahimi

    Original Article 17 July 2021 Pages: 1859 - 1869

    

29. Clinical, neuroradiological and genetic findings in a cohort of patients with multiple Cerebral Cavernous Malformations

    • Silvia Lanfranconi
    • Lorenzo Piergallini
    • Giacomo Pietro Comi

    Original Article 06 August 2021 Pages: 1871 - 1878

    

30. Comparing the effects of crocin at different doses on excitability and long-term potentiation in the CA1 area, as well as the electroencephalogram responses of rats under chronic stress

    • Azadehalsadat Hosseini Dastgerdi
    • Maryam Radahmadi
    • Ali Asghar Pourshanazari

    Original Article 03 July 2021 Pages: 1879 - 1887

    

31. RNA-seq analysis of ischemia stroke and normal brain in a tree shrew model with or without type 2 diabetes mellitus

    • Ling Zhao
    • Shiying Huang
    • Tingyu Ke

    Original Article 21 August 2021 Pages: 1889 - 1901

    

32. Possible role of rice bran extract in microglial modulation through PPAR-gamma receptors in alzheimer’s disease mice model

    • Shimaa Saad El-Din
    • Sahar Abd Elwahab
    • Zeinab A. Nour

    Original Article 27 May 2021 Pages: 1903 - 1915

    

33. Changes in activity of µ- and m-calpains and signs of neuroinflammation in the hippocampus and striatum of rats after single intraperitoneal injection of subseptic dose of endotoxin

    • Viktoriya Maystrenko
    • Irina Ivleva
    • Marina Karpenko

    Original Article 20 May 2021 Pages: 1917 - 1928

    

34. Evaluation of matrix metalloproteinase-9 plasma levels in untreated new Relapsing–remitting multiple sclerosis patients and their first-degree family

    • Mahsa Samangooei
    • Mojtaba Farjam
    • Saam Noroozi

    Original Article 11 June 2021 Pages: 1929 - 1934

    

35. Nitrosative stress parameters and the level of oxidized DNA bases in patients with multiple sclerosis

    • Vitalijs Borisovs
    • Jevgenijs Bodrenko
    • Nikolajs Sjakste

    Original Article 21 August 2021 Pages: 1935 - 1941

    

36. Neuroprotective effect of green and roasted coffee bean extracts on cerebral ischemia-induced injury in rats

    • Sara Rizk
    • Heba Taha
    • Hatem K. Amin

    Original Article 02 July 2021 Pages: 1943 - 1956

    

37. L-carnitine protects DNA oxidative damage induced by phenylalanine and its keto acid derivatives in neural cells: a possible pathomechanism and adjuvant therapy for brain injury in phenylketonuria

    • Jéssica Lamberty Faverzani
    • Aline Steinmetz
    • Carmen Regla Vargas

    Original Article 03 July 2021 Pages: 1957 - 1968

    

38. Hesperetin ameliorates diabetes-associated anxiety and depression-like behaviors in rats via activating Nrf2/ARE pathway

    • Xia Zhu
    • Yu-Meng Zhang
    • Yao-Wu Liu

    Original Article 17 July 2021 Pages: 1969 - 1983

    

39. The effect of salmon calcitonin against glutamate-induced cytotoxicity in the C6 cell line and the roles the inflammatory and nitric oxide pathways play

    • Ahmet Sevki Taskiran
    • Merve Ergul

    Original Article 09 August 2021 Pages: 1985 - 1993

    

40. Peripheral viral challenge increases c-fos level in cerebral neurons

    • Tiffany J. Petrisko
    • Gregory W. Konat

    Original Article 18 August 2021 Pages: 1995 - 2002

    

41. Sevoflurane impedes glioma progression via regulating circ_0000215/miR-1200/NCR3LG1 axis

    • Zhitao Zhao
    • Baofeng Gao
    • Ruiming Gao

    Original Article 30 August 2021 Pages: 2003 - 2014

    

42. The antioxidant and neuroprotective effects of the Psychotria camptopus Verd. Hook. (Rubiaceae) stem bark methanol extract contributes to its antiepileptogenic activity against pentylenetetrazol kindling in male Wistar rats

    • Aliance Romain Fokoua
    • Abayomi Mayowa Ajayi
    • Télesphore Benoît Nguelefack

    Original Article 30 August 2021 Pages: 2015 - 2027

    

43. Experimental study of pre- and postnatal caffeine exposure and its observable effects on selected neurotransmitters and behavioural attributes at puberty

    • Joshua O. Owolabi
    • Kehinde A. Adefule
    • Philip O. Ogunnaike

    Original Article 30 August 2021 Pages: 2029 - 2046

    

44. Bee venom acupuncture therapy ameliorates neuroinflammatory alterations in a pilocarpine-induced epilepticus model

    • Abeer Mohamed Abd El-Hameed
    • Abdelaziz S. A. Abuelsaad
    • Abdelwahab Khalil

    Original Article 17 June 2021 Pages: 2047 - 2058

    

45. Long non-coding RNA Gm11974 aggravates oxygen–glucose deprivation-induced injury via miR-122-5p/SEMA3A axis in ischaemic stroke

    • Ling Yang
    • Lijuan Wang
    • Ping Liu

    Original Article 02 August 2021 Pages: 2059 - 2069

    

46. Differential involvement of hippocampal subfields in Niemann-Pick type C disease: a case–control study

    • Pierre Wibawa
    • Florian Kurth
    • Mark Walterfang

    Original Article 19 June 2021 Pages: 2071 - 2078

    

47. Exogenous IGF-1 improves tau pathology and neuronal pyroptosis in high-fat diet mice with cognitive dysfunction

    • Guanghong Sui
    • Caixia Yang
    • Feng Wang

    Original Article 16 July 2021 Pages: 2079 - 2088

    

48. Neuroprotective effects of coenzyme Q10 in Parkinson's model via a novel Q10/miR-149-5p/MMPs pathway

    • Elham Ghasemloo
    • Hossein Mostafavi
    • Seyyed Saeid Mousavi

    Original Article 06 August 2021 Pages: 2089 - 2100

    

49. Analysis of platelet-derived growth factor receptor A and oligodendrocyte transcription factor 2 markers following Hydroxychloroquine administration in animal induced multiple sclerosis model

    • Hajar Amin Safaei
    • Seyed Mehdi Eftekhari
    • Mehdi Aliomrani

    Original Article 03 August 2021 Pages: 2101 - 2110

    

50. Expression analysis of cytokine transcripts in inflammatory demyelinating polyradiculoneuropathy

    • Fwad Nicknafs
    • Soudeh Ghafouri-Fard
    • Mohammad Taheri

    Original Article 25 June 2021 Pages: 2111 - 2118