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Application of Modeling and Simulation to Identify a Shortened Study Duration and Novel Bioequivalence Metric for a Long-Acting Intrauterine System Satish SharanSungwoo ChoiLiang Zhao Research Article 02 May 2022 Article: 63
Effect of the Size of Protein Therapeutics on Brain Pharmacokinetics Following Systematic Administration Hsueh-Yuan ChangShengjia WuDhaval K. Shah Research Article 02 May 2022 Article: 62
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Tumor Growth Inhibition-Overall Survival (TGI-OS) Model for Subgroup Analysis Based on Post-Randomization Factors: Application for Anti-drug Antibody (ADA) Subgroup Analysis of Atezolizumab in the IMpower150 Study Kenta YoshidaPhyllis ChanRené Bruno Brief/Technical Note 28 April 2022 Article: 58
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International Regulatory Collaboration on the Analysis of Nitrosamines in Metformin-Containing Medicines David A. KeireRobert BreamMichael Wierer Research Article Open access 21 April 2022 Article: 56
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DISSOLUTION PROFILE SIMILARITY ANALYSES—STATISTICAL PRINCIPLES, METHODS AND CONSIDERATIONS Thomas HoffelderDavid LeblondAndreas Abend Meeting Report 06 April 2022 Article: 54
A Model-Based Approach to Bridging Plasma and Dried Blood Spot Concentration Data for Phase 3 Verubecestat Trials Marissa F. DockendorfDavid JaworowiczJulie A. Stone Research Article 06 April 2022 Article: 53
An Investigation of Instability in Dried Blood Spot Samples for Pharmacokinetic Sampling in Phase 3 Trials of Verubecestat Melanie AndersonMarissa F. DockendorfEric Woolf Research Article 06 April 2022 Article: 52
The AAPS Journal Theme Issue: Rising Stars in Drug Delivery and Novel Carriers Aliasger K. SalemJuliane NguyenKristy M. Ainslie Editorial 05 April 2022 Article: 51
Current Approaches for Dissolution Similarity Assessment, Requirements, and Global Expectations Andreas M. AbendLimin ZhangSandra Sharp-Suarez Meeting Report 29 March 2022 Article: 50
An IQ Consortium Perspective on Connecting Dissolution Methods to In Vivo Performance: Analysis of an Industrial Database and Case Studies to Propose a Workflow Aktham AburubYuan ChenChristophe Tisaert Research Article 29 March 2022 Article: 49
Population Pharmacodynamic Modeling of Eflornithine-Based Treatments Against Late-Stage Gambiense Human African Trypanosomiasis and Efficacy Predictions of L-eflornithine-Based Therapy Carl AmilonMikael BobergRasmus Jansson-Löfmark Research Article Open access 25 March 2022 Article: 48
Targeted Delivery of Endosomal Escape Peptides to Enhance Immunotoxin Potency and Anti-cancer Efficacy Joseph Ryan PolliPing ChenJoseph P. Balthasar Research Article 25 March 2022 Article: 47
Semisolid Pharmaceutical Product Characterization Using Non-invasive X-ray Microscopy and AI-Based Image Analytics Thean YeohLisa MaShawn Zhang Protocols in Pharmaceutical Sciences 21 March 2022 Article: 46
In Vitro Assessment of Transporter Mediated Perpetrator DDIs for Several Hepatitis C Virus Direct-Acting Antiviral Drugs and Prediction of DDIs with Statins Using Static Models Xiaoyan ChuGrace Hoyee ChanChristine Fandozzi Research Article 21 March 2022 Article: 45
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