The role of conjugation reactions in detoxication Karl Walter BockWerner LilienblumBarbara S. Bock-Hennig Review Pages: 22 - 29
“A” esterases and their role in regulating the toxicity of organophosphates Colin H. WalkerMichael I. Mackness Review Pages: 30 - 33
Role of gut in xenobiotic metabolism Osmo HänninenPirjo Lindström-SeppäKai Pelkonen Review Pages: 34 - 36
Fingerprinting rat liver microsomal cytochromes P-450 as a means of delineating sexually distinctive forms John B. SchenkmanLeonard V. FavreauIngela Jansson Original Investigations Pages: 43 - 51
Characterization of hepatic and pulmonary cytochromes P-450 in 3-methylcholanthrene-treated hamsters Minro WatanabeHiroshi FujiiMiwa Tanno Original Investigations Pages: 52 - 58
Effects of dietary fat and aflatoxin B1 on microsomal monooxygenase activity H. S. Nyandieka Original Investigations Pages: 59 - 60
Formation of reactive metabolites from benzene R. SnyderL. JowaT. Rushmore Original Investigations Pages: 61 - 64
The in vitro/in vivo comparative metabolism of 4-aminobiphenyl using isolated hepatocytes S. D. JatoeJ. W. Gorrod Original Investigations Pages: 65 - 68
Hydrolysis of 4-methylumbelliferyl sulfate in periportal and pericentral areas of the liver lobule Irene AnundiFrederick C. KauffmanRonald G. Thurman Original Investigations Pages: 69 - 72
Pharmacokinetics of the neurotoxin n-hexane in rat and man J. G. FilserH. PeterN. Fedtke Original Investigations Pages: 77 - 80
The 14CO2 breath test: facilities and limitations of a rapid and noninvasive method for in vivo evaluation of modified hepatic cytochrome P-450 — a critique M. BrüchL. KlingE. Maser Original Investigations Pages: 81 - 85
Stereometabolism of styrene in man Manfred KornRoman WodarzFriedrich Wilhelm Schmahl Original Investigations Pages: 86 - 88
Human liver debrisoquine 4-hydroxylase: test for specifity toward various monooxygenase substrates and model of the active site Thomas WolffLinda M. DistlerathF. Peter Guengerich Original Investigations Pages: 89 - 90
The oxidation of isomeric amino and acetamidobiphenyls by rat hepatic microsomal preparations Nejla BayraktarM. KajbafJ. W. Gorrod Short Communication Pages: 91 - 92
Factors influencing the caffeine test for cytochrome P 448-dependent liver function R. JoeresH. KlinkerE. Richter Short Communication Pages: 93 - 94
A general theory of chemical cytotoxicity based on a molecular model of the living cell, the Bhopalator Sungchul Ji Review Pages: 95 - 102
Cellular effects of reactive intermediates: Nephrotoxicity of S-conjugates of amino acids M. W. AndersAdnan A. ElfarraLawrence H. Lash Review Pages: 103 - 108
Studies on liver toxicants Friedrich E. BeyhlDieter G. Mayer Original Investigations Pages: 109 - 111
Interaction between glucose diet and ethanol on rat liver microsomal induction and liver plasma membrane damage in chronic hexachlorobenzene intoxication V. NikolaevE. NaydenovaK. Tchernev Original Investigations Pages: 112 - 114
Tetrachloromethane metabolism in vivo under normoxia and hypoxia H. DürkC. KlessenH. Frank Original Investigations Pages: 115 - 121
Interaction of carbon tetrachloride and progesterone metabolism in liver microsomes from triacetyloleandomycin-treated rats Christian LarroqueReinhard Lange Original Investigations Pages: 122 - 123
Drug-induced intrahepatic cholestasis: characterization of different pathomechanisms Herbert KrellJürgen MetzErich Pfaff Original Investigations Pages: 124 - 130
Effect of clofibrate on DNA synthesis in rat liver and kidney J. SeifertH. Mostecká Short Communication Pages: 131 - 132
Oxygen radical formation and DNA damage due to enzymatic reduction of bleomycin-Fe(III) I. MahmutogluM. E. ScheulenH. Kappus Original Investigations Pages: 150 - 153
Positive correlation between decreased cellular uptake, NADPH-glutathione reductase activity and adriamycin resistance in Ehrlich ascites tumor lines Max E. ScheulenHarald HoenschCarl G. Schmidt Original Investigations Pages: 154 - 157
Detection of oxygen activation and determination of the activity of antioxidants towards reactive oxygen species by use of the chemiluminigenic probes luminol and lucigenin Regine KahlAndreas WeimannAlfred G. Hildebrandt Original Investigations Pages: 158 - 162
In vitro aging of red blood cells and lipid peroxidation Hermann EinseleMichael R. ClemensHerbert Remmer Original Investigations Pages: 163 - 166
Alcohol consumption and hepatic fibrosis affect the fatty acid composition of red blood cells and their susceptibility to lipid peroxidation Michael R. ClemensHermann EinseleHerbert Remmer Original Investigations Pages: 167 - 169
No evidence for lysophospholipid formation during peroxidation of phospholipids by NADPH-cytochrome P-450 reductase and iron ions J. KostruchaH. Kappus Short Communication Pages: 170 - 173
Significance of various enzymes in the control of reactive metabolites F. Oesch Review Pages: 174 - 178
The role of biotransformation in the genotoxicity of allylic compounds Erwin EderKlaus DornbuschGudrun Fischer Original Investigations Pages: 182 - 186
Estimation of exposure to alkylating carcinogens by the GC-MS determination of adducts to hemoglobin and nucleic acid bases in urine E. BaileyP. B. FarmerD. E. G. Shuker Orginal Investigations Pages: 187 - 191
Effects of bile acids on the mutagenicity and recombinogenicity of triethylene melamine in yeast strains MP1 and D61.M Rudolf Fahrig Orginal Investigations Pages: 192 - 197
Expression and inducibility of drug-metabolizing enzymes in preneoplastic and neoplastic lesions of rat liver during nitrosamine-induced hepatocarcinogenesis H. W. KunzA. BuchmannF. Oesch Original Investigations Pages: 198 - 203
Enzymatic denitrosation of diphenylnitrosamine: activation or inactivation? K. E. AppelS. GörsdorfA. G. Hildebrandt Original Investigations Pages: 204 - 208
Dose-response of promotion by polychlorinated biphenyls and chloroform in rat liver foci bioassay Erhard DemlDoris Oesterle Original Investigations Pages: 209 - 211
Overdose toxicity studies versus threshold: elements of biology must be incorporated into risk assessment Alfred G. Hildebrandt Review Pages: 217 - 223
Contribution of toxicology towards risk assessment of carcinogens Robert Kroes Review Pages: 224 - 228
Relationship of basic research in toxicology to environmental standard setting: the case of polybrominated biphenyls in Michigan Steven D. AustCynthia D. MillisLarry Holcomb Review Pages: 229 - 237
Principles and problems in assessing prenatal toxicity Diether NeubertIbrahim ChahoudReinhard Meister Review Pages: 238 - 245