Abstract
Chiral styrene metabolites obtained during initial styrene exposure of test persons were determined in urine samples using capillary gas chromatography. A typical time-dependent urinary concentration profile of one person over a 49-h period is presented and compared with the results of a previous study of occupationally exposed workers and an unexposed control group. Maximum levels of excretion of all styrene metabolites were observed at about the end of a 9-h workshift. Forty hours after exposure, the L/D-ratio of mandelic acid had subsided to the initial value, and the L/D-ratio of phenylethylene glycol to a value equal or slightly above the initial value.
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Dedicated to Professor Dr. med. Herbert Remmer on the occasion of his 65th birthday
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Korn, M., Wodarz, R., Drysch, K. et al. Stereometabolism of styrene in man. Arch Toxicol 60, 86–88 (1987). https://doi.org/10.1007/BF00296954
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DOI: https://doi.org/10.1007/BF00296954