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The beta subunit of AMP-activated protein kinase is critical for cell cycle progression and parasite development in Toxoplasma gondii Jichao YangXuke YangBang Shen Original Article 28 September 2022 Article: 532
Single cell analysis of PANoptosome cell death complexes through an expansion microscopy method Yaqiu WangNagakannan PandianThirumala-Devi Kanneganti Original Article 28 September 2022 Article: 531
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A single-cell transcriptomic atlas of the human ciliary body Bingsheng LouLei ZengFeng Zhang Original Article Open access 26 September 2022 Article: 528
Melatonin relieves hepatic lipid dysmetabolism caused by aging via modifying the secondary bile acid pattern of gut microbes Dongqin WeiYizhou LiChao Sun Original Article 23 September 2022 Article: 527
CAPRIN1P512L causes aberrant protein aggregation and associates with early-onset ataxia Andrea Delle VedoveJanani NatarajanBrunhilde Wirth Original Article Open access 22 September 2022 Article: 526
The multiple facets of mitochondrial regulations controlling cellular thermogenesis Florian BeignonNaig GueguenGuy Lenaers Review 20 September 2022 Article: 525
The ERK5/NF-κB signaling pathway targets endometrial cancer proliferation and survival Nora Diéguez-MartínezSergio Espinosa-GilJose M. Lizcano Original Article Open access 19 September 2022 Article: 524
L-glutamate requires β-catenin signalling through Frizzled7 to stimulate porcine intestinal stem cell expansion Ying-chao QinJia-yi ZhouXiu-qi Wang Original Article 19 September 2022 Article: 523
SOX9 in organogenesis: shared and unique transcriptional functions Zhenhua MingBrittany ViningVincent Harley Review Open access 17 September 2022 Article: 522
The rs1001179 SNP and CpG methylation regulate catalase expression in chronic lymphocytic leukemia Marilisa GalassoElisa Dalla PozzaMaria T. Scupoli Original Article Open access 16 September 2022 Article: 521
PHLDA1 promotes glioblastoma cell growth via sustaining the activation state of Ras Jiutao WangNing YaoZigang Dong Original Article 15 September 2022 Article: 520
The P2Y11 receptor of human M2 macrophages activates canonical and IL-1 receptor signaling to translate the extracellular danger signal ATP into anti-inflammatory and pro-angiogenic responses Dominik KlaverHubert GanderMartin Thurnher Original Article Open access 15 September 2022 Article: 519
Therapeutic effects of peptide P140 in a mouse periodontitis model Kentaro AkiyamaKyaw Thu AungSylviane Muller Original Article 15 September 2022 Article: 518
Metabolic reprogramming in the OPA1-deficient cells Wenting DaiZhichao WangLei Jiang Original Article 14 September 2022 Article: 517
Deficiency of the Src homology phosphatase 2 in podocytes is associated with renoprotective effects in mice under hyperglycemia Ming-Fo HsuYoshihiro ItoFawaz G. Haj Original Article 14 September 2022 Article: 516
Perilipin-2 limits remyelination by preventing lipid droplet degradation Melanie LoixElien WoutersJerome J. A. Hendriks Original Article 13 September 2022 Article: 515
A dominant negative mutation uncovers cooperative control of caudal Wolffian duct development by Sprouty genes Gisela AltésMarta VaqueroMario Encinas Original Article Open access 13 September 2022 Article: 514
Novel lectin-based chimeric antigen receptors target Gb3-positive tumour cells Ana Valeria MeléndezRubí M.-H. Velasco CárdenasSusana Minguet Original Article Open access 12 September 2022 Article: 513
Heterocomplexes between the atypical chemokine MIF and the CXC-motif chemokine CXCL4L1 regulate inflammation and thrombus formation Markus BrandhoferAdrian HoffmannJürgen Bernhagen Original Article Open access 12 September 2022 Article: 512
The heterogeneity of microglial activation and its epigenetic and non-coding RNA regulations in the immunopathogenesis of neurodegenerative diseases Chaoyi LiJie RenYu Tang Review 06 September 2022 Article: 511
Potent anticancer activity of a novel iridium metallodrug via oncosis Enrique Ortega-ForteSamanta Hernández-GarcíaFernando Gandía-Herrero Original Article Open access 06 September 2022 Article: 510
The present and future of immunocytokines for cancer treatment Dennis Y. GoutLotte S. GroenMarjolein van Egmond Review Open access 06 September 2022 Article: 509