Immunopotentiation and Delivery Systems for Antigens for Single-Step Immunization: Recent Trends and Progress M. Zahirul I. KhanJoan P. OpdebeeckIan G. Tucker ReviewPaper Pages: 2 - 11
Feasibility Study on Spray-Drying Protein Pharmaceuticals: Recombinant Human Growth Hormone and Tissue-Type Plasminogen Activator Marco MumenthalerChung C. HsuRodney Pearlman OriginalPaper Pages: 12 - 20
Moisture-Induced Aggregation of Lyophilized Insulin Henry R. CostantinoRobert LangerAlexander M. Klibanov OriginalPaper Pages: 21 - 29
Transcellular Transport of Benzole Acid Across Caco-2 Cells by a pH-Dependent and Carrier-Mediated Transport Mechanism Akira TsujiHitomi TakanagaTetsuya Terasaki OriginalPaper Pages: 30 - 37
Intracellular Visualization of Ampicillin-Loaded Nanoparticles in Peritoneal Macrophages Infected in Vitro with Salmonella typhimurium Huguette Pinto-AlphandaryOlivier BallandPatrick Couvreur OriginalPaper Pages: 38 - 46
Conformational Analysis, Molecular Modeling, and Quantitative Structure–Activity Relationship Studies of Agents for the Inhibition of Astrocytic Chloride Transport Chris L. WallerSteven D. WyrickForrest T. Smith OriginalPaper Pages: 47 - 53
Measurement of Glass Transition Temperatures of Freeze-Concentrated Solutes by Differential Scanning Calorimetry Lih-Min HerSteven L. Nail OriginalPaper Pages: 54 - 59
Clearance Mechanisms of Atrial and Brain Natriuretic Peptides in Rats Yukiya HashimotoKazuwa NakaoRyohei Hori OriginalPaper Pages: 60 - 64
Acidic Fibroblast Growth Factor: Evaluation of Topical Formulations in a Diabetic Mouse Wound Healing Model Bozena MatuszewskaMartina KeoganJoseph V. Bondi OriginalPaper Pages: 65 - 71
Acid-Catalyzed Peptide Bond Hydrolysis of Recombinant Human Interleukin 11 Richard A. KenleyNicholas W. Warne OriginalPaper Pages: 72 - 76
Primary Culture of Rat Gastric Epithelial Cells as an in Vitro Model to Evaluate Antiulcer Agents Hongjian ZhengPraful K. ShahKenneth L. Audus OriginalPaper Pages: 77 - 82
Diffusion Rates and Transport Pathways of Fluorescein Isothiocyanate (FITC)-Labeled Model Compounds Through Buccal Epithelium A. Janet HoogstraateChristopher CullanderHarry E. Boddé OriginalPaper Pages: 83 - 89
Effect of Cyclodextrins on Protein Binding of Drugs: The Diflunisal/Hydroxypropyl-β-Cyclodextrin Model Case Evangelos E. SiderisMichael A. KoupparisPanayotis E. Macheras OriginalPaper Pages: 90 - 95
Analysis of the Combined Effect of 1-Menthol and Ethanol as Skin Permeation Enhancers Based on a Two-Layer Skin Model Daisuke KobayashiTakayasu MatsuzawaMasayuki Kimura OriginalPaper Pages: 96 - 103
Interaction Between Drugs and Pressure-Sensitive Adhesives in Transdermal Therapeutic Systems Takemasa KokuboKenji SugibayashiYasunori Morimoto OriginalPaper Pages: 104 - 107
Preparation, Characterization, and Pharmaceutical Application of Linear Dextrins. III. Drug Release from Fatty Suppository Bases Containing Amylodextrin Gerrit H. P. Te WierikAnko C. EissensCoenraad F. Lerk OriginalPaper Pages: 108 - 110
An Organic Acid-Induced Sigmoidal Release System for Oral Controlled-Release Preparations Shinji NarisawaMinako NagataKazuo Noda OriginalPaper Pages: 111 - 116
Bioavailability of Flumequine After Semisimultaneous Administration to Veal Calves Bert A. MeijerKristel G. F. CeyssensBen I. J. A. C. de Grève OriginalPaper Pages: 117 - 121
Biodistribution of Mixed Fluorocarbon–Hydrocarbon Dowel Molecules Used as Stabilizers of Fluorocarbon Emulsions: A Quantitative Study by Fluorine Nuclear Magnetic Resonance (NMR) Leila ZarifMichéle PostelRené Follana OriginalPaper Pages: 122 - 127
Validation of a Variable Direction Hysteresis Minimization Pharmacodynamic Approach: Cardiovascular Effects of Alfentanil Nishit B. ModiPeter Veng-Pedersen OriginalPaper Pages: 128 - 135
pH-Related Changes in the Absorption of Dipyridamole in the Elderly Tanya L. RussellRosemary R. BerardiJennifer B. Dressman OriginalPaper Pages: 136 - 143
Disposition of Glycosidase Inhibitors in the Isolated Perfused Rat Liver: Hepatobiliary and Subcellular Concentration Gradients of 1-Deoxymannojirimycin and N-Methyl-1-Deoxynojirimycin Esther D. FaberJohannes H. ProostDirk K. F. Meijer OriginalPaper Pages: 144 - 150
Influence of a Fat-Rich Meal on the Pharmacokinetics of a New Oral Formulation of Cyclosporine in a Crossover Comparison with the Market Formulation Edgar A. MuellerJohn M. KovarikKlaus Kutz OriginalPaper Pages: 151 - 155
Comparison of the Pharmacokinetics of an Ondansetron Solution (8 mg) When Administered Intravenously, Orally, to the Colon, and to the Rectum Poe-Hirr HsyuJ. Frederick PritchardWilliam H. Barr OriginalPaper Pages: 156 - 159
Pharmacokinetic Analysis of in Vivo Metabolism of Amino Acid or Dipeptide Conjugates of Salicylic Acid in Rabbit Intestinal Microorganisms Koyo NishidaMitsuhiko KidoJunzo Nakamura OriginalPaper Pages: 160 - 164
Epimerization and Hydrolysis of Dalvastatin, a New Hydroxymethylglutaryl Coenzyme A (HMG-CoA) Reductase Inhibitor Chong Min Won OriginalPaper Pages: 165 - 170
Psychometric Evaluation of Measures of Organizational Commitment and Intention to Quit Among Pharmaceutical Scientists Sheldon Xiaodong KongAlbert I. WertheimerWilliam F. McGhan OriginalPaper Pages: 171 - 180
Interaction of Zidovudine (Azidothymidine) with Isoprinosine and Probenecid in Macaca fascicularis Sayed M. H. Al-HabetConnie NosbischJashvant D. Unadkat Note Pages: 181 - 183