Volume 14, Issue 3

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August 2010

Special Issue :Multi-Component Reaction (MCR) 2009

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23 articles in this issue

Multi-component reactions and related chemistries
Maxim A. Mironov
Editorial 23 July 2010 Pages: 409 - 409
Efficiency in chemistry: from hydrogen autotransfer to multicomponent catalysis
Francisco Alonso
Francisco Foubelo
Miguel Yus
Full-Length Paper 11 September 2009 Pages: 411 - 424
Multicomponent synthesis of dihydrobenzoxazepinones, bearing four diversity points, as potential α-helix mimics
Luca Banfi
Andrea Basso
Renata Riva
Full-Length Paper 28 November 2009 Pages: 425 - 442
Three-component synthesis of benzo[b][1,5]thiazepines via coupling–addition–cyclocondensation sequence
Benjamin Willy
Thomas J. J. Müller
Full-Length Paper 16 February 2010 Pages: 443 - 453
Intramolecular cyclization of 1-(2-arylethyl)tetrahydro-6-hydroxy-1H-pyrimidin-2-thiones: effect of substituents on reactivity
Alexander S. Fisuyk
Aleksey Y. Mukanov
Nikolay V. Poendaev
Full-Length Paper 16 March 2010 Pages: 455 - 462
Multicomponent reactions of amines with aldehydes and H₂S as efficient route to heterocycles and thioaza macrocycles
V. R. Akhmetova
G. R. Khabibullina
N. N. Murzakova
Full-Length Paper 04 April 2010 Pages: 463 - 471
An efficient, multicomponent approach for solvent-free synthesis of 2-amino-4H-chromene scaffold
M. Reza Naimi-Jamal
Sara Mashkouri
Ali Sharifi
Full-Length Paper 07 April 2010 Pages: 473 - 477
One-pot multicomponent synthesis of two novel thiolactone scaffolds
B. Beck
S. Srivastava
Alexander Dömling
Full-length paper 21 April 2010 Pages: 479 - 491
Efficient entry into hydrazinopeptide-like structures via sequential Ugi reactions
Ekaterina Bushkova
Vladislav Parchinsky
Mikhail Krasavin
Short Communication 10 November 2009 Pages: 493 - 499
A mild and efficient synthesis of monofluorinated α-lactam pseudopeptides via a novel dehydrofluorination of Ugi products
Nianjin Liu
Song Cao
Xuhong Qian
Short Communication 17 November 2009 Pages: 501 - 506
[Hmim]TFA catalyzed multicomponent reaction: direct, mild, and efficient procedure for the synthesis of 1,2-dihydroquinazoline derivatives
Minoo Dabiri
Mahboobeh Bahramnejad
Sahareh Bashiribod
Short Communication 29 January 2010 Pages: 507 - 512
On the industrial applications of MCRs: molecular diversity in drug discovery and generic drug synthesis
Cédric Kalinski
Michael Umkehrer
Günther Ross
SI - MCR2009 16 March 2010 Pages: 513 - 522
Diversity oriented heterocyclizations of pyruvic acids, aldehydes and 5-amino-N-aryl-1H-pyrazole-4-carboxamides: catalytic and temperature control of chemoselectivity
Yana I. Sakhno
Svetlana V. Shishkina
Valentin A. Chebanov
SI - MCR2009 14 March 2010 Pages: 523 - 531
A novel regiospecific cascade synthesis of sulfonamide derivatives from N-(2-polychloroethyl)sulfonamides via chloroaziridine intermediates in the presence of mercaptoethanol
Igor B. Rozentsveig
Aleksandr V. Popov
Galina G. Levkovskaya
SI - MCR2009 25 March 2010 Pages: 533 - 541
Reaction of isocyanides with thiophenols and gem-diactivated olefins: a one-pot synthesis of substituted 2-aminopyrroles
Anna N. Kolontsova
Maria N. Ivantsova
Maxim A. Mironov
OriginalPaper 07 March 2010 Pages: 543 - 550
Predicting subcellular location of proteins using integrated-algorithm method
Yu-Dong Cai
Lin Lu
Jian-Feng He
Full-Length Paper 07 August 2009 Pages: 551 - 558
Pharmacophore generation and atom-based 3D-QSAR of novel 2-(4-methylsulfonylphenyl)pyrimidines as COX-2 inhibitors
Ujashkumar A. Shah
Hemantkumar S. Deokar
Vithal M. Kulkarni
Full-Length Paper 11 August 2009 Pages: 559 - 568
One-pot synthesis of 4-arylquinolines from aromatic aminoketones and vinylphosphonium salts
Sakineh Asghari
Mohammad Qandalee
Zahra Sobhaninia
Full-Length Paper 13 August 2009 Pages: 569 - 574
Unexpected synthesis of N-methylbenzo[d]isoxazolium hydroxides under microwave irradiation conditions
Hassan Valizadeh
Majid M. Heravi
Mohammad Amiri
Full-Length Paper 14 August 2009 Pages: 575 - 579
Quantitative and qualitative models for carcinogenicity prediction for non-congeneric chemicals using CP ANN method for regulatory uses
Natalja Fjodorova
Marjan Vračko
Gerrit Schüürmann
Full-Length Paper 15 August 2009 Pages: 581 - 594
In silico structure-based design of a novel class of potent and selective small peptide inhibitor of Mycobacterium tuberculosis Dihydrofolate reductase, a potential target for anti-TB drug discovery
Manoj Kumar
Rajakrishnan Vijayakrishnan
Gita Subba Rao
Full-Length Paper 21 August 2009 Pages: 595 - 604
Multicomponent reactions of dimethyl methoxymalonate and dialkyl acetylenedicarboxylate in the presence of N-Nucleophiles: one-pot synthesis of 2H-pyridinyl-2-butenedioates in water
Mohammad A. Khalilzadeh
Zinatossadat Hossaini
Samaneh Kharian
Full-Length Paper 11 September 2009 Pages: 605 - 609
One-pot synthesis of functionalized 4-oxo-2-thioxo-1,3-thiazinanes from primary amines, CS₂, and itaconic anhydride
Issa Yavari
Mehdi Sirouspour
Sanaz Souri
Full-Length Paper 11 September 2009 Pages: 611 - 615

Volume 14, Issue 3

Multi-component reactions and related chemistries

Efficiency in chemistry: from hydrogen autotransfer to multicomponent catalysis

Multicomponent synthesis of dihydrobenzoxazepinones, bearing four diversity points, as potential α-helix mimics

Three-component synthesis of benzo[b][1,5]thiazepines via coupling–addition–cyclocondensation sequence

Intramolecular cyclization of 1-(2-arylethyl)tetrahydro-6-hydroxy-1H-pyrimidin-2-thiones: effect of substituents on reactivity

Multicomponent reactions of amines with aldehydes and H₂S as efficient route to heterocycles and thioaza macrocycles

An efficient, multicomponent approach for solvent-free synthesis of 2-amino-4H-chromene scaffold

One-pot multicomponent synthesis of two novel thiolactone scaffolds

Efficient entry into hydrazinopeptide-like structures via sequential Ugi reactions

A mild and efficient synthesis of monofluorinated α-lactam pseudopeptides via a novel dehydrofluorination of Ugi products

[Hmim]TFA catalyzed multicomponent reaction: direct, mild, and efficient procedure for the synthesis of 1,2-dihydroquinazoline derivatives

On the industrial applications of MCRs: molecular diversity in drug discovery and generic drug synthesis

Diversity oriented heterocyclizations of pyruvic acids, aldehydes and 5-amino-N-aryl-1H-pyrazole-4-carboxamides: catalytic and temperature control of chemoselectivity

A novel regiospecific cascade synthesis of sulfonamide derivatives from N-(2-polychloroethyl)sulfonamides via chloroaziridine intermediates in the presence of mercaptoethanol

Reaction of isocyanides with thiophenols and gem-diactivated olefins: a one-pot synthesis of substituted 2-aminopyrroles

Predicting subcellular location of proteins using integrated-algorithm method

Pharmacophore generation and atom-based 3D-QSAR of novel 2-(4-methylsulfonylphenyl)pyrimidines as COX-2 inhibitors

One-pot synthesis of 4-arylquinolines from aromatic aminoketones and vinylphosphonium salts

Unexpected synthesis of N-methylbenzo[d]isoxazolium hydroxides under microwave irradiation conditions

Quantitative and qualitative models for carcinogenicity prediction for non-congeneric chemicals using CP ANN method for regulatory uses

In silico structure-based design of a novel class of potent and selective small peptide inhibitor of Mycobacterium tuberculosis Dihydrofolate reductase, a potential target for anti-TB drug discovery

Multicomponent reactions of dimethyl methoxymalonate and dialkyl acetylenedicarboxylate in the presence of N-Nucleophiles: one-pot synthesis of 2H-pyridinyl-2-butenedioates in water

One-pot synthesis of functionalized 4-oxo-2-thioxo-1,3-thiazinanes from primary amines, CS₂, and itaconic anhydride

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