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Multicomponent reactions of amines with aldehydes and H2S as efficient route to heterocycles and thioaza macrocycles

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Abstract

Here we provide new experimental results on multicomponent reactions of amines with aldehydes and H2S in the directed synthesis of functionally-substituted 1,3-thiazetidines, 1,3,5-dithiazinanes, 1,3,5-thiadiazinanes, 1,5-dithia-3,7-diazacyclooctanes, and thioaza macrocycles. X-ray analysis gave insight into the structure of the synthesized compounds. New kinds of multicomponent reactions (MCR) have been discovered and characterized.

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Authors and Affiliations

  1. Institute of Petrochemistry and Catalysis of Russian Academy of Sciences, Prospekt Oktyabrya, 141, Ufa, 450075, Russia

    V. R. Akhmetova, G. R. Khabibullina, E. B. Rakhimova, R. A. Vagapov, R. R. Khairullina, Z. T. Niatshina & N. N. Murzakova

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  1. V. R. Akhmetova
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  2. G. R. Khabibullina
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  3. E. B. Rakhimova
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  4. R. A. Vagapov
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  5. R. R. Khairullina
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  6. Z. T. Niatshina
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  7. N. N. Murzakova
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Correspondence to V. R. Akhmetova.

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Akhmetova, V.R., Khabibullina, G.R., Rakhimova, E.B. et al. Multicomponent reactions of amines with aldehydes and H2S as efficient route to heterocycles and thioaza macrocycles. Mol Divers 14, 463–471 (2010). https://doi.org/10.1007/s11030-010-9248-3

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  • DOI: https://doi.org/10.1007/s11030-010-9248-3

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