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Curcumin and Neurodegenerative Diseases

From Traditional to Translational Medicines

  • Book
  • © 2023

Overview

  • Deliberates the role of secondary metabolites of Curcuma in neurodegenerative diseases

  • Confers strategic nanoparticle-based delivery of curcumin to neurons crossing Blood-Brain-Barrier

  • Elucidates the role of nanoformulations in Alzheimer’s and Perkinson’s diseases

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About this book

This book explores the potential benefits of turmeric, and specifically curcumin, in the treatment and prevention of neurodegenerative diseases. The book covers various aspects of turmeric, including its traditional use in Ayurveda and Chinese medicine, secondary metabolites, curcuminoids, and sesquiterpenoids found in turmeric, as well as the use of nano curcumin in neurodegenerative diseases. It discusses the different ways in which turmeric can be used to treat neurodegenerative diseases, including as a therapy for brain diseases, curcumin-induced neuroprotection in cerebral ischemia, and neural stem cell therapy in combination with curcumin. It also discusses the role of nano curcumin in neurodegenerative diseases, including its potential use in the treatment of Alzheimer's disease. The book provides the scientific evidence behind the use of turmeric and its compounds in the treatment of neurodegenerative diseases, such as Alzheimer's and Parkinson's disease. Overall, this book is an invaluable resource for researchers and healthcare professionals interested in exploring the potential benefits of turmeric and curcumin in the treatment and prevention of neurodegenerative diseases.


Keywords

Table of contents (22 chapters)

  1. General

  2. Traditional Uses of Curcuma and Secondary Metabolites

  3. Curcuma, Curcumin and Its Nanoparticles in Neurodegenerative Diseases

  4. Nanocurcumin and Nanocurcumin-mediated Drug Delivery

Editors and Affiliations

  • Department of Biotechnology, Sant Gadge Baba Amravati University, Amravati, India

    Mahendra Rai

  • Department of Chemistry, Federal University of PiauĂ­, Teresina, Brazil

    Chistiane M. Feitosa

About the editors

Professor Mahender Rai is UGC- Basic Science Research Faculty Fellow and former head of the Department of Biotechnology, Sant Gadge Baba Amravati University, Amravati, Maharashtra, India. Presently, he is a visiting Scientist at the Department of Chemistry, Federal University of Piaui, Teresina, Brazil. Professor Rai has published more than 450 research papers in Indian and foreign peer-reviewed journals, 70 books and more than 102 articles.  He is a member of several scientific societies.  His area of expertise includes microbial biotechnology and nanobiotechnology. Currently, the main research interest of his group is the green synthesis of metal nanoparticles particularly using fungi and their applications as nano antimicrobials against pathogenic microbes. He has received several prestigious awards, including the Father T.A. Mathias award (1989) from the All-India Association for Christian Higher Education, and the Medini award by the Government of India. In 2015 (October-November) he was a visiting scientist at Nanotechnology Center, VSB Technological University of Ostrava.  He was awarded NAWA fellowship by Polish Government from 2021-2023. Recently, he has been Featured in Stanford's list of the top 2% of scientists in Nanoscience and nanotechnology

Professor Chistiane M. Feitosa is a professor of chemistry at Federal University of Piaui (UFPI), Teresina, Brazil. She participates in the master's and doctorate programs at the UFPI Teresina campus: Pharmaceutical Sciences with emphasis on Production and quality control of medicines and Master and Doctorate in Chemistry in the area of Natural Products Chemistry. With rich experience in chemistry of natural products, Professor Feitosa’s main areas of interest are bioactive metabolites from plants, enzyme acetylcholinesterase, and antioxidants in the context of Alzheimer's disease. She received CNPq Technological Productivity Scholarship in 2015-2018. Moreover, she has supervised more than 30 students in the master's and doctoral programs in chemistry and pharmaceutical sciences programs at UFPI. Professor Feitosa is well known for her research on the application of natural products in neurodegenerative diseases. Her present research is focused on the role of Curcuma and curcumin in neurodegenerative diseases. She has published more than 70 research papers, several book chapters, and 10 books from different reputed publications.

Bibliographic Information

  • Book Title: Curcumin and Neurodegenerative Diseases

  • Book Subtitle: From Traditional to Translational Medicines

  • Editors: Mahendra Rai, Chistiane M. Feitosa

  • DOI: https://doi.org/10.1007/978-981-99-7731-4

  • Publisher: Springer Singapore

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd. 2023

  • Hardcover ISBN: 978-981-99-7730-7Published: 16 February 2024

  • Softcover ISBN: 978-981-99-7733-8Due: 02 March 2025

  • eBook ISBN: 978-981-99-7731-4Published: 15 February 2024

  • Edition Number: 1

  • Number of Pages: XVIII, 480

  • Number of Illustrations: 42 b/w illustrations, 52 illustrations in colour

  • Topics: Neurosciences, Biomedicine, general, Biomedicine, general

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