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Turmeric and Alzheimer’s Disease: Therapeutic Effects of Curcuminoids, Curcumin, and Turmerone

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Curcumin and Neurodegenerative Diseases

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Abstract

Alzheimer’s disease (AD) is the most common form of dementia, with a significant prevalence over the age of 60. The progressive degeneration of brain tissue and memory loss are challenges to finding drugs efficiently. Curcuma longa (turmeric) has shown encouraging results in both rhizome extracts and essential oils for the presence of curcuminoids and turmerone, respectively, which showed in several studies efficient actions such as acetylcholinesterase inhibition, anti-inflammatory processes, suppression of amyloid β activity, and improvement of brain cells. In this context, the aim of this chapter is to focus on the chemical analysis and therapeutic effects of curcuminoids, curcumin, and turmerone of turmeric plant in Alzheimer’s disease.

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Authors and Affiliations

  1. PADETEC – Technological Development Park, Federal University of Ceará, Fortaleza, Brazil

    Celma de Oliveira Barbosa

  2. Chemistry Department, Federal University of Ceará, Fortaleza, Brazil

    João Francisco Câmara Neto

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  1. Celma de Oliveira Barbosa
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  1. Department of Biotechnology, Sant Gadge Baba Amravati University, Amravati, Maharashtra, India

    Mahendra Rai

  2. Department of Chemistry, Federal University of Piauí, Teresina, Brazil

    Chistiane M. Feitosa

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de Oliveira Barbosa, C., Neto, J.F.C. (2023). Turmeric and Alzheimer’s Disease: Therapeutic Effects of Curcuminoids, Curcumin, and Turmerone. In: Rai, M., Feitosa, C.M. (eds) Curcumin and Neurodegenerative Diseases. Springer, Singapore. https://doi.org/10.1007/978-981-99-7731-4_8

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