Lithium Effects on Granulopoiesis and Immune Function

  • Arthur H. Rossof
  • William A. Robinson

Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 127)

Table of contents

  1. Front Matter
    Pages i-xiv
  2. Introduction

    1. Ghanshyam N. Pandey, John M. Davis
      Pages 15-59
  3. Mechanisms of Lithium-Induced Granulocytosis

    1. G. Rothstein, A. K. Oshita, W. G. Harker, G. Lonngi, R. D. Christensen
      Pages 87-98
    2. Dharmvir S. Verma, Gary Spitzer, Axel R. Zander, Miloslav A. Beran, Karel A. Dicke
      Pages 111-126
  4. Animal Models

    1. Robert A. Joyce, Paul A. Chervenick
      Pages 145-154
    2. A. H. Rossof, K. M. Fehir, H. S. Budd, A. Murthy, S. G. Economou
      Pages 155-166
    3. William P. Hammond, David C. Dale
      Pages 167-173
  5. Lithium Attenuation of Anti-Cancer Chemotherapy

    1. Dominique J. Charron, Thierry Schmitt, Laurent Degos
      Pages 175-186
    2. Peter G. Steinherz, Gerald Rosen, Fereshteh Ghavimi, Norma Wollner, Ying Wang, Denis R. Miller
      Pages 231-243
    3. U. Visca, F. Mensi, M. P. Spina, R. Bombara, B. Giraldi, A. Massari et al.
      Pages 245-255

About this book


This monograph contains papers which resulted from an international workshop on the effects of lithium on the hematopoietic and immunologic systems. The meeting was held at the John L. and Beatrice Keeshin International Biomedical Systems Planning Center of Rush University in Eagle River, Wisconsin from June 6 through June 9, 1979. The object of this conference was to bring together scientists from around the world with an interest in the effects of lithium and its potential use in human disease to bolster and stimulate the hematologic and immune systems. These topics seemed to us to be important and the time seemed right for bringing together the workers in these fields to exchange ideas and recent research results. We sought to bring together basic research scientists trying to uncover the mechanism of action of lithium in the stimulation of granulo­ poiesis and in its immunologic effects, together with those involved in clinical care and the use of lithium as a therapeutic tool in neoplastic and non-neoplastic disorders. This was the first use of the Keeshin Center for such a program. The sessions were conducted in a relaxed atmosphere with a good deal of give-and-take by all the participants. The editors of this book hope that it will be useful as the first volume completely devoted to these applications of lithium in these new and, as yet, incompletely developed fields.


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Editors and affiliations

  • Arthur H. Rossof
    • 1
  • William A. Robinson
    • 2
  1. 1.Rush Medical CollegeChicagoUSA
  2. 2.University of Colorado Medical CenterDenverUSA

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag US 1980
  • Publisher Name Springer, Boston, MA
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-4757-0261-3
  • Online ISBN 978-1-4757-0259-0
  • Series Print ISSN 0065-2598
  • About this book