1. Mdivi-1 Modulates Macrophage/Microglial Polarization in Mice with EAE via the Inhibition of the TLR2/4-GSK3β-NF-κB Inflammatory Signaling Axis

   • Xiaoqin Liu
   • Xiaojuan Zhang
   • Cungen Ma

   OriginalPaper 07 October 2021 Pages: 1 - 16

   

2. Molecular Profiles of Amyloid-β Proteoforms in Typical and Rapidly Progressive Alzheimer’s Disease

   • Aneeqa Noor
   • Saima Zafar
   • Inga Zerr

   OriginalPaper Open access 07 October 2021 Pages: 17 - 34

   

3. Nitric Oxide Signaling Pathway in Ventral Tegmental Area is Involved in Regulation of 7,8-Dihydroxyflavone on Alcohol Consumption in Rats

   • Qing Gao
   • Tao Yang
   • Yan-Zhong Guan

   OriginalPaper 07 October 2021 Pages: 35 - 46

   

4. Mesenchymal Stem Cell-derived Extracellular Vesicles Transmitting MicroRNA-34a-5p Suppress Tumorigenesis of Colorectal Cancer Through c-MYC/DNMT3a/PTEN Axis

   • Jiangning Zhao
   • Huanrong Lin
   • Kunsong Huang

   OriginalPaper Open access 08 October 2021 Pages: 47 - 60

   

5. NME1 Protects Against Neurotoxin-, α-Synuclein- and LRRK2-Induced Neurite Degeneration in Cell Models of Parkinson’s Disease

   • Jayanth Anantha
   • Susan R. Goulding
   • Gerard W. O’Keeffe

   OriginalPaper Open access 08 October 2021 Pages: 61 - 76

   

6. Function of Oncogene Mycn in Adult Neurogenesis and Oligodendrogenesis

   • Jiao Chen
   • Zhonghui Guan

   OriginalPaper Open access 08 October 2021 Pages: 77 - 92

   

7. Midazolam Exposure Impedes Oligodendrocyte Development via the Translocator Protein and Impairs Myelination in Larval Zebrafish

   • Daojie Xu
   • Bin Wang
   • Yingwei Wang

   Original Article 09 October 2021 Pages: 93 - 106

   

8. Joint-Tissue Integrative Analysis Identified Hundreds of Schizophrenia Risk Genes

   • Yong Wu
   • Xiao-Lin Yu
   • Yi Li

   OriginalPaper 09 October 2021 Pages: 107 - 116

   

9. Differential Effects of Experimental Retinal Detachment on S- and M/L-Cones in Rats

   • Glyn Chidlow
   • Weng Onn Chan
   • Robert J. Casson

   OriginalPaper 11 October 2021 Pages: 117 - 136

   

10. Role of Neurons and Glia Cells in Wound Healing as a Novel Perspective Considering Platelet as a Conventional Player

    • Samir K. Beura
    • Abhishek R. Panigrahi
    • Sunil K. Singh

    OriginalPaper 11 October 2021 Pages: 137 - 160

    

11. Ferrostatin-1 Alleviates White Matter Injury Via Decreasing Ferroptosis Following Spinal Cord Injury

    • Hongfei Ge
    • Xingsen Xue
    • Shengli Hu

    OriginalPaper 12 October 2021 Pages: 161 - 176

    

12. Lactate and Pyruvate Activate Autophagy and Mitophagy that Protect Cells in Toxic Model of Parkinson’s Disease

    • Evgeniya I. Fedotova
    • Ludmila P. Dolgacheva
    • Alexey V. Berezhnov

    OriginalPaper 13 October 2021 Pages: 177 - 190

    

13. Gene Therapy Approach with an Emphasis on Growth Factors: Theoretical and Clinical Outcomes in Neurodegenerative Diseases

    • Della Grace Thomas Parambi
    • Khalid Saad Alharbi
    • Bijo Mathew

    ReviewPaper 15 October 2021 Pages: 191 - 233

    

14. The Possible Protective Role of Dark Chocolate Against Acrylamide Neurotoxicity in Weaning Rats Cerebellum

    • Doaa M. Hassan
    • Nermeen N. Welson
    • Hanan D. Yassa

    OriginalPaper 18 October 2021 Pages: 234 - 244

    

15. Regulation of Brain Primary Cilia Length by MCH Signaling: Evidence from Pharmacological, Genetic, Optogenetic, and Chemogenic Manipulations

    • Wedad Alhassen
    • Yuki Kobayashi
    • Amal Alachkar

    OriginalPaper 19 October 2021 Pages: 245 - 265

    

16. Melatonin Pretreatment Protects Against Status epilepticus, Glutamate Transport, and Oxidative Stress Induced by Kainic Acid in Zebrafish

    • Ana Caroline Salvador de Farias
    • Karolyne de Pieri Pickler
    • Eduardo Pacheco Rico

    OriginalPaper 19 October 2021 Pages: 266 - 275

    

17. Sex-Stratified Single-Cell RNA-Seq Analysis Identifies Sex-Specific and Cell Type-Specific Transcriptional Responses in Alzheimer’s Disease Across Two Brain Regions

    • Stella A. Belonwu
    • Yaqiao Li
    • Marina Sirota

    OriginalPaper Open access 20 October 2021 Pages: 276 - 293

    

18. Remote but not Distant: a Review on Experimental Models and Clinical Trials in Remote Ischemic Conditioning as Potential Therapy in Ischemic Stroke

    • Inês Mollet
    • João Pedro Marto
    • Helena L. A. Vieira

    ReviewPaper 22 October 2021 Pages: 294 - 325

    

19. Circadian Regulation and Clock-Controlled Mechanisms of Glycerophospholipid Metabolism from Neuronal Cells and Tissues to Fibroblasts

    • Mario E. Guido
    • Natalia M. Monjes
    • Gabriela A. Salvador

    ReviewPaper 26 October 2021 Pages: 326 - 353

    

20. Implications of Phosphoinositide 3-Kinase-Akt (PI3K-Akt) Pathway in the Pathogenesis of Alzheimer’s Disease

    • Manish Kumar
    • Nitin Bansal

    ReviewPaper 26 October 2021 Pages: 354 - 385

    

21. Essential Role of Sptan1 in Cochlear Hair Cell Morphology and Function Via Focal Adhesion Signaling

    • Qingxiu Yao
    • Hui Wang
    • Shankai Yin

    OriginalPaper Open access 27 October 2021 Pages: 386 - 404

    

22. SNARE Proteins Mediate α-Synuclein Secretion via Multiple Vesicular Pathways

    • Xiaofang Zhao
    • Yuan Guan
    • Claire Xi Zhang

    OriginalPaper 27 October 2021 Pages: 405 - 419

    

23. Photobiomodulation Improves the Inflammatory Response and Intracellular Signaling Proteins Linked to Vascular Function and Cell Survival in the Brain of Aged Rats

    • Fabrízio dos Santos Cardoso
    • Fernanda Cristina Borini Mansur
    • Sérgio Gomes da Silva

    OriginalPaper 27 October 2021 Pages: 420 - 428

    

24. SIRT6 Negatively Regulates Schwann Cells Dedifferentiation via Targeting c-Jun During Wallerian Degeneration After Peripheral Nerve Injury

    • Ying Zou
    • Jiaqi Zhang
    • Jiasong Guo

    OriginalPaper 27 October 2021 Pages: 429 - 444

    

25. SARS-CoV-2 Spike Glycoprotein S1 Induces Neuroinflammation in BV-2 Microglia

    • Olumayokun A. Olajide
    • Victoria U. Iwuanyanwu
    • Alaa A. Al-Hindawi

    OriginalPaper Open access 28 October 2021 Pages: 445 - 458

    

26. Insights of Extracellular Vesicles of Mesenchymal Stem Cells: a Prospective Cell-Free Regenerative Medicine for Neurodegenerative Disorders

    • P. Vatsa
    • R. Negi
    • A. B. Pant

    ReviewPaper 29 October 2021 Pages: 459 - 474

    

27. Neuroinflammation in Primary Cultures of the Rat Spinal Dorsal Horn Is Attenuated in the Presence of Adipose Tissue–Derived Medicinal Signalling Cells (AdMSCs) in a Co-cultivation Model

    • Stephan Leisengang
    • Laura B. Heilen
    • Joachim Roth

    OriginalPaper Open access 30 October 2021 Pages: 475 - 494

    

28. A Novel SCA3 Knock-in Mouse Model Mimics the Human SCA3 Disease Phenotype Including Neuropathological, Behavioral, and Transcriptional Abnormalities Especially in Oligodendrocytes

    • Eva Haas
    • Rana D. Incebacak
    • Jeannette Hübener-Schmid

    OriginalPaper Open access 30 October 2021 Pages: 495 - 522

    

29. The Phenotypes and Mechanisms of NOTCH2NLC-Related GGC Repeat Expansion Disorders: a Comprehensive Review

    • Xiu-Rong Huang
    • Bei-Sha Tang
    • Ji-Feng Guo

    ReviewPaper 31 October 2021 Pages: 523 - 534

    

30. Recent Advances in Molecular Pathways and Therapeutic Implications Targeting Mitochondrial Dysfunction for Alzheimer’s Disease

    • Rishika Dhapola
    • Phulen Sarma
    • Dibbanti HariKrishna Reddy

    ReviewPaper 02 November 2021 Pages: 535 - 555

    

31. Individual Response to Radiation of Individuals with Neurofibromatosis Type I: Role of the ATM Protein and Influence of Statins and Bisphosphonates

    • Patrick Combemale
    • Laurène Sonzogni
    • Nicolas Foray

    OriginalPaper 02 November 2021 Pages: 556 - 573

    

32. Phosphodiesterase 10A Is a Critical Target for Neuroprotection in a Mouse Model of Ischemic Stroke

    • Mustafa C. Beker
    • Ahmet B. Caglayan
    • Ertugrul Kilic

    OriginalPaper 04 November 2021 Pages: 574 - 589

    

33. Alleviating Oxidative Damage–Induced Telomere Attrition: a Potential Mechanism for Inhibition by Folic Acid of Apoptosis in Neural Stem Cells

    • Zhenshu Li
    • Wen Li
    • Guowei Huang

    OriginalPaper 05 November 2021 Pages: 590 - 602

    

34. Dendritic Cell–Targeted Therapies to Treat Neurological Disorders

    • Asim Hussain
    • Hamza Rafeeq
    • Hafiz M. N. Iqbal

    Reviews 06 November 2021 Pages: 603 - 619

    

35. An Update on the Critical Role of α-Synuclein in Parkinson’s Disease and Other Synucleinopathies: from Tissue to Cellular and Molecular Levels

    • Iris N. Serratos
    • Elizabeth Hernández-Pérez
    • Abel Santamaría

    ReviewPaper 08 November 2021 Pages: 620 - 642

    

36. Neutrophil Extracellular Traps Exacerbate Ischemic Brain Damage

    • Congqin Li
    • Ying Xing
    • Yulong Bai

    ReviewPaper 08 November 2021 Pages: 643 - 656

    

37. Delineation of Neuroprotective Effects and Possible Benefits of AntioxidantsTherapy for the Treatment of Alzheimer’s Diseases by Targeting Mitochondrial-Derived Reactive Oxygen Species: Bench to Bedside

    • Vaibhav Walia
    • Deepak Kaushik
    • Ghulam Md Ashraf

    ReviewPaper 09 November 2021 Pages: 657 - 680

    

38. Correction to: Delineation of Neuroprotective Effects and Possible Benefits of AntioxidantsTherapy for the Treatment of Alzheimer’s Diseases by Targeting Mitochondrial-Derived Reactive Oxygen Species: Bench to Bedside

    • Vaibhav Walia
    • Deepak Kaushik
    • Ghulam Md Ashraf

    Correction 27 November 2021 Pages: 681 - 682

39. Targeting Tau Mitigates Mitochondrial Fragmentation and Oxidative Stress in Amyotrophic Lateral Sclerosis

    • Tiziana Petrozziello
    • Evan A. Bordt
    • Ghazaleh Sadri-Vakili

    OriginalPaper 10 November 2021 Pages: 683 - 702

    

40. Hypoglycemic Effect of Electroacupuncture at ST25 Through Neural Regulation of the Pancreatic Intrinsic Nervous System

    • Tiancheng Xu
    • Zhi Yu
    • Bin Xu

    OriginalPaper Open access 10 November 2021 Pages: 703 - 716

    

41. Differential Expression and Distinct Roles of Proteinase-Activated Receptor 2 in Microglia and Neurons in Neonatal Mouse Brain After Hypoxia-Ischemic Injury

    • Yicong Liu
    • Hui Li
    • Junjun Ni

    OriginalPaper 11 November 2021 Pages: 717 - 730