Pharmacokinetics and Bioequivalence of Two Formulations of Azithromycin Tablets: A Randomized, Single-Dose, Three-Period, Crossover Study in Healthy Chinese Volunteers Under Fasting and Fed Conditions Yingrong ChenLibing YeJie Wang Original Research Article Open access 30 May 2024
A Semi-Mechanistic Population Pharmacokinetic Model of Noscapine in Healthy Subjects Considering Hepatic First-Pass Extraction and CYP2C9 Genotypes Zhendong ChenMax TaubertUwe Fuhr Original Research Article Open access 29 May 2024
Pharmacokinetics of a Fixed-Dose Combination Product of Amlodipine, Losartan, Ezetimibe, and Rosuvastatin and Its Comparison with Co-administration of Four Individual Components in Healthy Participants Jin-Woo ParkHyewon ChungJi-Young Park Original Research Article Open access 22 May 2024
Normalization of Hemoglobin, Lactate Dehydrogenase, and Fatigue in Patients with Paroxysmal Nocturnal Hemoglobinuria Treated with Pegcetacoplan Brian P. MulherinMichael YehDavid Dingli Original Research Article Open access 10 May 2024
Retrospective Assessment of Translational Pharmacokinetic–Pharmacodynamic Modeling Performance: A Case Study with Apitolisib, a Dual PI3K/mTOR Inhibitor Anita MoeinJin Y. JinHarvey Wong Original Research Article Open access 03 May 2024
Evaluation of Ornidazole Tablets Bioequivalence in Chinese Healthy Participants Under Fasted and Fed Conditions Using Pharmacokinetic Parameters Yanrong WangYuanyuan HeLijing Gao Original Research Article Open access 22 April 2024
Future Perspectives of Pulmonary Arterial Hypertension: A Review of Novel Pipeline Treatments and Indications Maria Eugenia NovaraEnrica Di MartinoAlessio Provenzani Review Article Open access 22 March 2024 Pages: 13 - 28
Application of Transthoracic Echocardiography for Cardiac Safety Evaluation in the Clinical Development Process of Vaccines Against Streptococcus pyogenes Usman NakakanaAlimamy Serry-BanguraAshwani Kumar Arora Current Opinion Open access 18 March 2024 Pages: 1 - 12
Linezolid-Induced Thrombocytopenia in Patients with Renal Impairment: A Case Series, Review and Dose Advice S. R. E. LaarhuisC. H. M. KerskesD. J. Touw Case Report Open access 14 March 2024 Pages: 109 - 115
Effect of Daridorexant on the Pharmacokinetics of Midazolam, and on the Pharmacokinetics and Pharmacodynamics of Warfarin in Healthy Male Subjects Isabelle ZenklusenJasper DingemansePriska Kaufmann Original Research Article Open access 13 March 2024 Pages: 97 - 108
Bioequivalence Study of Tebipenem Pivoxil in Healthy Chinese Adults Rui HaoYiming ShaoYiwen Zhang Original Research Article Open access 07 March 2024 Pages: 89 - 96
Case Report: Life-Threatening Fluoxetine-Linked Postoperative Bleeding Informed by Pharmacogenetic Evaluation Sara RogersPatrick J. SilvaKenneth S. Ramos Case Report Open access 28 February 2024 Pages: 117 - 121
Pharmacokinetic and Safety Study of Bismuth Potassium Citrate Formulations in Healthy Subjects Hong-Yu LuoShuo-Guo XuYan Cheng Original Research Article Open access 12 February 2024 Pages: 81 - 87
Real-World Experience of Carglumic Acid for Methylmalonic and Propionic Acidurias: An Interim Analysis of the Multicentre Observational PROTECT Study Sufin YapDelphine LamireauVincenzo Giordano Original Research Article Open access 10 January 2024 Pages: 69 - 80
Drug–Drug Interaction Studies of Esmethadone (REL-1017) Involving CYP3A4- and CYP2D6-Mediated Metabolism Nicola FerriSara De MartinPaolo L. Manfredi Original Research Article Open access 27 November 2023 Pages: 51 - 68
Unveiling the Influence of a High-Fat Meal on the Pharmacokinetics of Oral Globalagliatin, A Glucokinase Activator, in Healthy Chinese Volunteers Maodi XuYaqin WangHaitang Xie Original Research Article Open access 20 November 2023 Pages: 41 - 50
Efficacy and Safety of Methylphenidate and Atomoxetine in Medication-Naive Children with Attention-Deficit Hyperactivity Disorder in a Real-World Setting Ying ZhangLi YinKaifeng Zhang Original Research Article Open access 20 November 2023 Pages: 29 - 39
A Guide to Expanding the Use of Buprenorphine Beyond Standard Initiations for Opioid Use Disorder James C. MillerMichael A. BrooksJohn F. Wurzel III Review Article Open access 08 November 2023 Pages: 339 - 362
Acknowledgement to Referees Acknowledgement to Referees Open access 08 November 2023 Pages: 297 - 299
Effect of High-Fat Food on the Pharmacokinetic Profile and Safety of SAF-189s, an ALK/ROS1 Inhibitor, in Healthy Chinese Adults Huiling QinYan TanWei Hu Original Research Article Open access 07 November 2023 Pages: 465 - 473
Human Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of ASC42, a Novel Farnesoid X Receptor Agonist Handan HeJinzi J. Wu Original Research Article Open access 02 November 2023 Pages: 453 - 464
Simvastatin Preferentially Targets FLT3/ITD Acute Myeloid Leukemia by Inhibiting MEK/ERK and p38-MAPK Signaling Pathways Genhong LiJingwei YaoBing Xu Original Research Article Open access 17 October 2023 Pages: 439 - 451
Analytical and Functional Similarity of the Biosimilar Candidate ABP 654 to Ustekinumab Reference Product Greg CantinQian LiuJennifer Liu Original Research Article Open access 13 October 2023 Pages: 421 - 438
Effect of Tucatinib on Cardiac Repolarization in Healthy Volunteers Ariel R. Topletz-EricksonJoAl G. MayorChristopher J. Endres Original Research Article Open access 26 September 2023 Pages: 411 - 419
Looking into the Kinetics of NT-proBNP and sST2 Changes in Patients with Heart Failure Treated with Sacubitril/Valsartan: A Hint to Different Therapeutic Pathways Massimo MapelliIrene MattavelliPiergiuseppe Agostoni Original Research Article Open access 13 September 2023 Pages: 397 - 402
Pharmacovigilance Study of Infigratinib: A Safety Analysis of the FDA Adverse Event Reporting System Dehua ZhaoXiaoqing LongJisheng Wang Original Research Article Open access 12 September 2023 Pages: 403 - 409
The Benefits and Risks of Switching from Fingolimod to Siponimod for the Treatment of Relapsing–Remitting and Secondary Progressive Multiple Sclerosis Martin VališAnat AchironZbyšek Pavelek Review Article Open access 28 August 2023 Pages: 331 - 338
Demonstration of Physicochemical and Functional Similarity of Biosimilar Adalimumab-aqvh to Adalimumab Yijia JiangTaruna AroraKaren J. Miller Original Research Article Open access 26 August 2023 Pages: 377 - 395
In-Use Stability of SB12 (Eculizumab, Soliris Biosimilar) Diluted in Saline and Dextrose Infusion Solution after an Extended Storage Period Minji TakHawon JeongSu Jin Park Original Research Article Open access 22 August 2023 Pages: 363 - 375
Tremor Induced by Cyclosporine, Tacrolimus, Sirolimus, or Everolimus: A Review of the Literature Aparna Wagle ShuklaCaroline LunnyAshutosh M. Shukla Review Article Open access 22 August 2023 Pages: 301 - 329
Comparative Efficacy of Different Drugs for the Treatment of Dilated Cardiomyopathy: A Systematic Review and Network Meta-analysis Xinyu TongLijuan ShenShu Lu Review Article Open access 09 August 2023 Pages: 197 - 210
Risk of Hyponatremia after Tramadol/Acetaminophen Single-Pill Combination Therapy: A Real-World Study Based on the OMOP–CDM Database Yu Jeong LeeJinmi KimHarin Rhee Original Research Article Open access 28 July 2023 Pages: 289 - 296
Physicochemical and Functional Similarity Assessment Between Proposed Bevacizumab Biosimilar BAT1706 and Reference Bevacizumab Di CaoChunping DengCuihua Liu Original Research Article Open access 22 July 2023 Pages: 267 - 288
Biochemical Characterization of a New 10% IVIG Preparation [IgG Next Generation (BT595)/Yimmugo®] Obtained from a Manufacturing Process Preserving IgA/IgM Potential of Human Plasma Christian DuellbergAchim HannappelOliver Maneg Original Research Article Open access 19 July 2023 Pages: 245 - 255
Efficacy and Safety of Apatinib in Patients with Recurrent Glioblastoma Hao LinXinli ZhouXiaohua Liang Original Research Article Open access 19 July 2023 Pages: 239 - 244
Bioavailability of Melatonin after Administration of an Oral Prolonged-Release Tablet and an Immediate-Release Sublingual Spray in Healthy Male Volunteers Samira Ait AbdellahVéronique RaverotBruno Claustrat Original Research Article Open access 12 July 2023 Pages: 257 - 265
Hepatotoxicity of AKR1C3 Inhibitor BAY1128688: Findings from an Early Terminated Phase IIa Trial for the Treatment of Endometriosis Jan HilpertEsther Groettrup-WolfersCharles Chapron Original Research Article Open access 09 July 2023 Pages: 221 - 237
Bioavailability of Cariban® Capsules: A Modified-Release Fixed-Dose Combination of Doxylamine and Pyridoxine to Relieve Nausea and Vomiting During Pregnancy Paula Saz-LealLaura Zamorano-DomínguezKatia Urso Original Research Article Open access 15 June 2023 Pages: 185 - 195
Predictive Potential of Acido-Basic Properties, Solubility and Food on Bioequivalence Study Outcome: Analysis of 128 Studies Dejan KrajcarRebeka JerebIztok Grabnar Original Research Article Open access 10 June 2023 Pages: 211 - 220
N-Acetyl-L-Cysteine Reduces Cervical Carcinogenesis by Promoting Apoptosis Wenping GuoWang Jing Original Research Article Open access 02 June 2023 Pages: 165 - 174
A Randomized, Double-Blind, Parallel-Controlled Phase I Study Comparing the Pharmacokinetics, Safety, and Immunogenicity of SCT510 to Bevacizumab (Avastin®) in Healthy Chinese Males Jing WuGuolan WuJianzhong Shentu Original Research Article Open access 29 May 2023 Pages: 175 - 183
A Phase I Study to Investigate the Safety, Tolerability and Pharmacokinetics of Napabucasin Combined with Sorafenib in Japanese Patients with Unresectable Hepatocellular Carcinoma Takuji OkusakaManabu MorimotoRie Kageyama Original Research Article Open access 15 May 2023 Pages: 99 - 107
Safety and Effectiveness of Rasburicase in the Control of Hyperuricemia in Pediatric Patients with Non-Hodgkin’s Lymphoma and Acute Leukemia: An Open-Label, Single-Arm, Multi-center, Interventional Study Tianyou WangXiaofan ZhuMinlu Zhang Original Research Article Open access 10 May 2023 Pages: 129 - 140
Single-Centre Real-World Study on Drug Survival and Effectiveness of Brodalumab for Treatment of Psoriasis and Psoriatic Arthritis Cathrine Dawn Büttner ElgaardLars IversenKasper Fjellhaugen Hjuler Original Research Article Open access 08 May 2023 Pages: 155 - 163
Estetrol: From Preclinical to Clinical Pharmacology and Advances in the Understanding of the Molecular Mechanism of Action Céline GérardJean-Michel Foidart Review Article Open access 03 May 2023 Pages: 77 - 92
Development of a Biosimilar of Agalsidase Beta for the Treatment of Fabry Disease: Preclinical Evaluation André B. P. van KuilenburgCarla E. M. HollakMariana Papouchado Original Research Article Open access 21 April 2023 Pages: 141 - 153
Pharmacokinetics and Bioequivalence of Abiraterone Acetate Tablets in Healthy Chinese Volunteers: An Open, Randomized, Single-Dose, Three-Period, Three-Sequence Crossover Study Zhao-xin WuChen-jing WangYu Cao Original Research Article Open access 03 April 2023 Pages: 121 - 127
Efficacy of Baricitinib in Patients with Refractory Adult-Onset Still’s Disease Ziyi SunRongqi LiXin Li Original Research Article Open access 03 April 2023 Pages: 109 - 120
Case Report: Simultaneously Induced Neutropenia and Hemolysis After a Single Metamizole Dose Raphael AllgaierArne KandulskiHauke Christian Tews Case report Open access 29 March 2023 Pages: 93 - 98
A Nontrivial Analysis of Patient Safety Risk from Parenteral Drug- and Medical Device-Borne Endotoxin Edward C. Tidswell Original Research Article Open access 24 February 2023 Pages: 65 - 76
