1. Position Paper on Post-Traumatic Headache: The Relationship Between Head Trauma, Stress Disorder, and Migraine

   • Giorgio Lambru
   • Silvia Benemei
   • Paolo Martelletti

   Commentary Open access 28 November 2020 Pages: 1 - 13

2. Comparison of Crude Population-Level Indicators of Opioid Use and Related Harm in New Zealand and Ontario (Canada)

   • Benedikt Fischer
   • Dimitri Daldegan-Bueno
   • Wayne Jones

   Commentary Open access 31 December 2020 Pages: 15 - 23

3. CDC’s Efforts to Quantify Prescription Opioid Overdose Deaths Fall Short

   • John F. Peppin
   • John J. Coleman

   Commentary Open access 24 March 2021 Pages: 25 - 38

   

4. Basivertebral Nerve Ablation for the Treatment of Vertebrogenic Pain

   • Ivan Urits
   • Nazir Noor
   • Omar Viswanath

   Review Open access 31 October 2020 Pages: 39 - 53

5. Pharmacological Management of Painful Peripheral Neuropathies: A Systematic Review

   • Andreas Liampas
   • Martina Rekatsina
   • Panagiotis Zis

   Review Open access 03 November 2020 Pages: 55 - 68

   

6. A Comprehensive Review of Over the Counter Treatment for Chronic Low Back Pain

   • Jacquelin Peck
   • Ivan Urits
   • Omar Viswanath

   Review Open access 04 November 2020 Pages: 69 - 80

7. Use of Cryotherapy for Managing Chronic Pain: An Evidence-Based Narrative

   • Carol Garcia
   • Jay Karri
   • Alaa Abd-Elsayed

   Review Open access 14 December 2020 Pages: 81 - 100

   

8. Burst Motor Cortex Stimulation Evokes Sustained Suppression of Thalamic Stroke Pain: A Narrative Review and Single-Case Overview

   • Martin Nüssel
   • Melanie Hamperl
   • Thomas Kinfe

   Review Open access 16 December 2020 Pages: 101 - 114

   

9. Interventional Radiofrequency Treatment for the Sympathetic Nervous System: A Review Article

   • Nicholas A. Zacharias
   • Jay Karri
   • Alaa Abd-Elsayed

   Review Open access 12 January 2021 Pages: 115 - 141

   

10. Cervical Proprioception Impairment in Neck Pain-Pathophysiology, Clinical Evaluation, and Management: A Narrative Review

    • Baogan Peng
    • Liang Yang
    • Yanqing Liu

    Review Open access 12 January 2021 Pages: 143 - 164

    

11. Efficacy and Safety of Methylnaltrexone for the Treatment of Opioid-Induced Constipation: A Meta-analysis of Randomized Controlled Trials

    • Ying-Ying Zhang
    • Rong Zhou
    • Wan-Jie Gu

    Review Open access 11 February 2021 Pages: 165 - 179

    

12. Management of Musculoskeletal Pain: An Update with Emphasis on Chronic Musculoskeletal Pain

    • Salah N. El-Tallawy
    • Rohit Nalamasu
    • Paul J. Christo

    Review Open access 11 February 2021 Pages: 181 - 209

    

13. Structural and Functional Brain Changes in Migraine

    • Sait Ashina
    • Enrico Bentivegna
    • Katharina Eikermann-Haerter

    Review Open access 16 February 2021 Pages: 211 - 223

14. Food for Special Medical Purposes and Nutraceuticals for Pain: A Narrative Review

    • Roberto Casale
    • Zaira Symeonidou
    • Antonella Paladini

    Review Open access 16 February 2021 Pages: 225 - 242

15. Correction to: Food for Special Medical Purposes and Nutraceuticals for Pain: A Narrative Review

    • Roberto Casale
    • Zaira Symeonidou
    • Antonella Paladini

    Correction Open access 09 April 2021 Pages: 243 - 244

16. Pain, Smell, and Taste in Adults: A Narrative Review of Multisensory Perception and Interaction

    • Angela Sandri
    • Maria Paola Cecchini
    • Michele Tinazzi

    Review Open access 26 February 2021 Pages: 245 - 268

    

17. COVID-19 and the Opioid Epidemic: Two Public Health Emergencies That Intersect With Chronic Pain

    • Laxmaiah Manchikanti
    • Rachana Vanaparthy
    • Joshua A. Hirsch

    Review Open access 14 March 2021 Pages: 269 - 286

    

18. Pain in Women: A Perspective Review on a Relevant Clinical Issue that Deserves Prioritization

    • Roberto Casale
    • Fabiola Atzeni
    • Cristina Tassorelli

    Review Open access 15 March 2021 Pages: 287 - 314

19. Analgesic Effect of Noninvasive Brain Stimulation for Neuropathic Pain Patients: A Systematic Review

    • Kun-Long Zhang
    • Hua Yuan
    • Ya-Yun Wang

    Review Open access 22 March 2021 Pages: 315 - 332

    

20. Postoperative Analgesic Efficacy of Erector Spinae Plane Block in Patients Undergoing Lumbar Spinal Surgery: A Systematic Review and Meta-Analysis

    • Min-jun Liu
    • Xu-yan Zhou
    • Qi-hong Shen

    Review Open access 07 April 2021 Pages: 333 - 347

    

21. Resting-State Magnetoencephalography Reveals Neurobiological Bridges Between Pain and Cognitive Impairment

    • Yoshihito Shigihara
    • Hideyuki Hoshi
    • Shin Konno

    Original Research Open access 23 October 2020 Pages: 349 - 361

    

22. Assessment of Awareness, Attitude and Desire for Labor Analgesia and Associated Factors Among Pregnant Women in Ethiopia: A Cross-Sectional Study

    • Misganaw Mengie Workie
    • Wubie Birlie Chekol
    • Yosef Belay Bizuneh

    Original Research Open access 27 October 2020 Pages: 363 - 376

    

23. Neurophysiological Assessments During Continuous Sedation Until Death Put Validity of Observational Assessments Into Question: A Prospective Observational Study

    • Stefaan Six
    • Steven Laureys
    • Reginald Deschepper

    Original Research Open access 05 November 2020 Pages: 377 - 390

    

24. Epidural Dexmedetomidine for Prevention of Intrapartum Fever During Labor Analgesia: A Randomized Controlled Trial

    • Li Li
    • Zeyong Yang
    • Wangping Zhang

    Original Research Open access 13 November 2020 Pages: 391 - 400

    

25. Oliceridine is Associated with Reduced Risk of Vomiting and Need for Rescue Antiemetics Compared to Morphine: Exploratory Analysis from Two Phase 3 Randomized Placebo and Active Controlled Trials

    • Timothy L. Beard
    • Cathy Michalsky
    • Eugene R. Viscusi

    Original Research Open access 18 November 2020 Pages: 401 - 413

    

26. Unmet Needs in Japanese Patients Who Report Insufficient Efficacy with Triptans for Acute Treatment of Migraine: Retrospective Analysis of Real-World Data

    • Koichi Hirata
    • Kaname Ueda
    • Tamas Treuer

    Original Research Open access 11 December 2020 Pages: 415 - 432

    

27. Effect of Single-Injection Thoracic Paravertebral Block via the Intrathoracic Approach for Analgesia After Single-Port Video-Assisted Thoracoscopic Lung Wedge Resection: A Randomized Controlled Trial

    • Lihong Hu
    • Xia Xu
    • Jinxian He

    Original Research Open access 09 January 2021 Pages: 433 - 442

    

28. Burden of Renal Events Associated with Nonsteroidal Anti-inflammatory Drugs in Patients with Osteoarthritis and Chronic Low Back Pain: A Retrospective Database Study

    • Takayuki Katsuno
    • Kanae Togo
    • Shogo Kikuchi

    Original Research Open access 13 January 2021 Pages: 443 - 455

    

29. Low Incidence of Opioid-Induced Respiratory Depression Observed with Oliceridine Regardless of Age or Body Mass Index: Exploratory Analysis from a Phase 3 Open-Label Trial in Postsurgical Pain

    • Marek Brzezinski
    • Gregory B. Hammer
    • Ashraf S. Habib

    Original Research Open access 21 January 2021 Pages: 457 - 473

    

30. The Effect of Ultrasound-Guided Erector Spinae Plane Block Combined with Dexmedetomidine on Postoperative Analgesia in Patients Undergoing Modified Radical Mastectomy: A Randomized Controlled Trial

    • Xunxun Wang
    • Guo Ran
    • Weiping Fang

    Original Research Open access 21 January 2021 Pages: 475 - 484

    

31. Tramadol/Dexketoprofen Analgesic Efficacy Compared with Tramadol/Paracetamol in Moderate to Severe Postoperative Acute Pain: Subgroup Analysis of a Randomized, Double-Blind, Parallel Group Trial—DAVID Study

    • Magdi Hanna
    • Antonio Montero
    • Giustino Varrassi

    Original Research Open access 11 February 2021 Pages: 485 - 503

    

32. Pain Study in X-Linked Adrenoleukodystrophy in Males and Females

    • Valeria Bachiocco
    • Marco Cappa
    • Anna M. Aloisi

    Original Research Open access 20 February 2021 Pages: 505 - 523

    

33. Continuous Wound Infiltration with Local Anesthetic Is an Effective and Safe Postoperative Analgesic Strategy: A Meta-Analysis

    • Xuan-zhang Huang
    • Jun-hua Zhao
    • Zhen-ning Wang

    Original Research Open access 22 February 2021 Pages: 525 - 538

    

34. A Retrospective, Multicenter, Quantitative Analysis of Patients’ Baseline Pain Quality (PROMIS-29) Entering into Pain and Spine Practices in the United States (ALIGN)

    • Jason E. Pope
    • Michael Fishman
    • Timothy R. Deer

    Original Research Open access 23 February 2021 Pages: 539 - 550

    

35. Nalbuphine Versus Ketorolac as an Adjuvant to Local Wound Infiltration Anesthesia in Open Colorectal Surgery: A Prospective Randomized Controlled Study

    • Yi-Feng Ren
    • Xi Fu
    • Feng-Ming You

    Original Research Open access 24 February 2021 Pages: 551 - 565

    

36. Effect of Occipital Nerve Stimulation (ONS) on the Orbicularis Oculi Reflex Triggered by a Standardized Air Flow in Patients with Chronic Migraine—A Prospective, Randomized, Interventional Study

    • Carl H. Göbel
    • Axel Heinze
    • Hartmut Göbel

    Original Research Open access 25 February 2021 Pages: 567 - 576

    

37. Comparison of Efficacy of Ketoprofen and Ibuprofen in Treating Pain in Patients with Rheumatoid Arthritis: A Systematic Review and Meta-Analysis

    • Fabiola Atzeni
    • Ignazio F. Masala
    • Piercarlo Sarzi-Puttini

    Original Research Open access 05 March 2021 Pages: 577 - 588

    

38. Common Clinical Practice for Low Back Pain Treatment: A Modified Delphi Study

    • Giustino Varrassi
    • Biagio Moretti
    • Giovanni Iolascon

    Original Research Open access 13 March 2021 Pages: 589 - 604

    

39. Personalizing Cancer Pain Therapy: Insights from the Rational Use of Analgesics (RUA) Group

    • Giustino Varrassi
    • Flaminia Coluzzi
    • Rational Use of Analgesics (RUA) Group

    Original Research Open access 17 March 2021 Pages: 605 - 617

40. Machine Learning Algorithm Guiding Local Treatment Decisions to Reduce Pain for Lung Cancer Patients with Bone Metastases, a Prospective Cohort Study

    • Zhiyu Wang
    • Jing Sun
    • Hui Zhao

    Original Research Open access 19 March 2021 Pages: 619 - 633

    

41. Correction to: Machine Learning Algorithm Guiding Local Treatment Decisions to Reduce Pain for Lung Cancer Patients with Bone Metastases, a Prospective Cohort Study

    • Zhiyu Wang
    • Jing Sun
    • Hui Zhao

    Correction Open access 11 April 2021 Pages: 635 - 635

42. Early Management of OnabotulinumtoxinA Treatment in Chronic Migraine: Insights from a Real-Life European Multicenter Study

    • Raffaele Ornello
    • Fayyaz Ahmed
    • Simona Sacco

    Original Research Open access 28 March 2021 Pages: 637 - 650

    

43. Does Inhaled Methoxyflurane Implement Fast and Efficient Pain Management in Trauma Patients? A Systematic Review and Meta-Analysis

    • Hong Liu
    • Xi Fu
    • Lin-Jiong Li

    Original Research Open access 10 April 2021 Pages: 651 - 674

    

44. Ultrasound-Guided Continuous Thoracic Paravertebral Infusion of Methylene Blue in the Treatment of Postherpetic Neuralgia: A Prospective, Randomized, Controlled Study

    • Mingxia Wang
    • Jinyuan Zhang
    • Xiangrui Wang

    Original Research Open access 11 April 2021 Pages: 675 - 689

    

45. Psychosocial, Functional, and Emotional Correlates of Long-Term Opioid Use in Patients with Chronic Back Pain: A Cross-Sectional Case–Control Study

    • Kenta Wakaizumi
    • Andrew D. Vigotsky
    • Marwan N. Baliki

    Original Research Open access 12 April 2021 Pages: 691 - 709

    

46. Switching From Pregabalin to Mirogabalin in Patients with Peripheral Neuropathic Pain: A Multi-Center, Prospective, Single-Arm, Open-Label Study (MIROP Study)

    • Yoshiyuki Kimura
    • Shigeki Yamaguchi
    • Masako Iseki

    Original Research Open access 15 April 2021 Pages: 711 - 727

    

47. Failure of SCS MR-Conditional Modes Due to High Impedance: A Review of Literature and Case Series

    • Rohan Jotwani
    • Alaa Abd-Elsayed
    • Neel Mehta

    Case Series Open access 21 November 2020 Pages: 729 - 737

48. Auricular Therapy for Treating Phantom Limb Pain Accompanied by Jumping Residual Limb: A Short Review and Case Study

    • Hongfang Tian
    • Hantong Hu
    • Dexiong Han

    Case Report Open access 04 March 2021 Pages: 739 - 749

    

49. Letter to the Editor: Comment on “Gabapentinoid Benefit and Risk Stratification: Mechanisms Over Myth”

    • Alyssa M. Peckham
    • Jordan R. Covvey
    • Kirk E. Evoy

    Letter Open access 09 February 2021 Pages: 751 - 755

50. Response to Comment on “Gabapentinoid Benefit and Risk Stratification: Mechanisms Over Myth”

    • Heath B. McAnally
    • Udo Bonnet

    Letter Open access 09 February 2021 Pages: 757 - 762