Vos T, Allen C, Arora M, Barber RM, Brown A, Carter A, et al. Global, regional, and national incidence, prevalence, and years lived with disability for 310 diseases and injuries, 1990–2015: a systematic analysis for the global burden of disease study 2015. Lancet. 2016;388(10053):1545–602.
Google Scholar
Vos T, Barber RM, Bell B, Bertozzi-Villa A, Biryukov S, Bolliger I, et al. Global, regional, and national incidence, prevalence, and years lived with disability for 301 acute and chronic diseases and injuries in 188 countries, 1990–2013: a systematic analysis for the global burden of disease study 2013. Lancet. 2015;386(9995):743–800.
Google Scholar
Deyo RA, Dworkin SF, Amtmann D, Andersson G, Borenstein D, Carragee E, et al. Report of the NIH task force on research standards for chronic low back pain. Phys Ther. 2015;95(2):e1–18.
PubMed
PubMed Central
Google Scholar
Hoy D, Brooks P, Blyth F, Buchbinder R. The epidemiology of low back pain. Best Pract Res Clin Rheumatol. 2010;24(6):769–81.
CAS
PubMed
Google Scholar
Maher C, Underwood M, Buchbinder R. Non-specific low back pain. Lancet. 2017;389(10070):736–47.
PubMed
Google Scholar
Will J, Bury D, Miller JA. Mechanical low back pain: prevention. Am Fam Physician. 2018;98(7):421–8.
PubMed
Google Scholar
Chaparro LE, Furlan AD, Deshpande A, Mailis-Gagnon A, Atlas S, Turk DC. Opioids compared to placebo or other treatments for chronic low-back pain. Cochrane Database Syst Rev. 2013. https://doi.org/10.1002/14651858.CD004959.pub4.
Article
PubMed
PubMed Central
Google Scholar
Prescott L. Kinetics and metabolism of paracetamol and phenacetin. Br J Clin Pharmacol. 1980;10(Suppl 2):291S-298S.
PubMed
PubMed Central
Google Scholar
Chandrasekharan NV, Dai H, Roos KLT, Evanson NK, Tomsik J, Elton TS, et al. COX-3, a cyclooxygenase-1 variant inhibited by acetaminophen and other analgesic/antipyretic drugs: cloning, structure, and expression. Proc Natl Acad Sci USA. 2002;99(21):13926–31.
CAS
PubMed
Google Scholar
Jozwiak-Bebenista M, Nowak JZ. Paracetamol: mechanism of action, applications and safety concern. Acta Pol Pharm. 2014;71(1):11–23.
CAS
PubMed
Google Scholar
Saragiotto BT, Machado GC, Ferreira ML, Pinheiro MB, Abdel Shaheed C, Maher CG. Paracetamol for low back pain. Cochrane Database Syst Rev. 2016;2016(6):CD012230.
PubMed Central
Google Scholar
Ostojic P, Radunovic G, Lazovic M, Tomanovic-Vujadinovic S. Ibuprofen plus paracetamol versus ibuprofen in acute low back pain: a randomized open label multicenter clinical study. Acta Reumatol Port. 2017;42(1):18–25.
PubMed
Google Scholar
Miki K, Ikemoto T, Hayashi K, Arai YC, Sekiguchi M, Shi K, et al. Randomized open-labbel non-inferiority trial of acetaminophen or loxoprofen for patients with acute low back pain. J Orthop Sci. 2018;23(3):483–7.
PubMed
Google Scholar
Bedaiwi MK, Sari I, Wallis D, O’Shea FD, Salonen D, Haroon N, et al. Clinical efficacy of celecoxib compared to acetaminophen in chronic nonspecific low back pain: results of a randomized controlled trial. Arthritis Care Res (Hoboken). 2016;68(6):845–52.
CAS
Google Scholar
Williams CM, Maher CG, Latimer J, McLachlan AJ, Hancock MJ, Day RO, et al. Efficacy of paracetamol for acute low-back pain: a double-blind, randomised controlled trial. Lancet. 2014;384(9954):1586–96.
CAS
PubMed
Google Scholar
Chou R, Deyo R, Friedly J, Skelly A, Weimer M, Fu R, et al. Systemic pharmacologic therapies for low back pain: a systematic review for an American College of physicians clinical practice guideline. Ann Intern Med. 2017;166(7):480–92.
PubMed
Google Scholar
Tetsunaga T, Tetsunaga T, Tanaka M, Nishida K, Takei Y, Ozaki T. Effect of tramadol/acetaminophen on motivation in patients with chronic low back pain. Pain Res Manag. 2016;2016:7458534.
PubMed
PubMed Central
Google Scholar
Oliveira CB, Maher CG, Pinto RZ, Traeger AC, Lin CWC, Chenot JF, et al. Clinical practice guidelines for the management of non-specific low back pain in primary care: an updated overview. Eur Spine J. 2018;27(11):2791–803.
PubMed
Google Scholar
Ejaz P, Bhojani K, Joshi VR. NSAIDs and kidney. J Assoc Physicians India. 2004;52:632–40.
CAS
PubMed
Google Scholar
Grosser T. Cardiovascular safety of celecoxib, naproxen, or ibuprofen for arthritis. N Engl J Med. 2017;375:2519–29.
Google Scholar
Enthoven WTM, Roelofs PDDM, Deyo RA, van Tulder MW, Koes BW. Non-steroidal anti-inflammatory drugs for chronic low back pain. N Engl J Med. 2016;375(26):2519–29.
Google Scholar
Allegrini A, Nuzzo L, Pavone D, Tavella-Scaringi A, Giangreco D, Bucci M, et al. Efficacy and safety of piroxicam patch versus piroxicam cream in patients with lumbar osteoarthritis: a randomized, placebo-controlled study. Arzneimittel-Forschung Drug Res. 2009;59(8):403–9.
CAS
Google Scholar
Berry H, Bloom B, Hamilton EBD, Swinson DR. Naproxen sodium, diflunisal, and placebo in the treatment of chronic back pain. Ann Rheum Dis. 1982;41(2):129–32.
CAS
PubMed
PubMed Central
Google Scholar
Birbara CA, Puopolo AD, Munoz DR, Sheldon EA, Mangione A, Bohidar NR, et al. Treatment of chronic low back pain with etoricoxib, a new cyclo-oxygenase-2 selective inhibitor: improvement in pain and disability—a randomized, placebo-controlled, 3-month trial. J Pain. 2003;4(6):307–15.
CAS
PubMed
Google Scholar
Coats TL, Borenstein DG, Nangia NK, Brown MT. Effects of valdecoxib in the treatment of chronic low back pain: results of a randomized, placebo-controlled trial. Clin Ther. 2004;26(8):1249–60.
CAS
PubMed
Google Scholar
Kivitz AJ, Gimbel JS, Bramson C, Nemeth MA, Keller DS, Brown MT, et al. Efficacy and safety of tanezumab versus naproxen in the treatment of chronic low back pain. Pain. 2013;154(7):1009–21.
CAS
PubMed
Google Scholar
Driessens M, Famaey JP, Orloff S, Chochrad I, Cleppe D, de Brabanter G, et al. Efficacy and tolerability of sustained-release ibuprofen in the treatment of patients with chronic back pain. Curr Ther Res. 1994;55(11):1283–92.
Google Scholar
Videman T, Osterman K. Double-blind parallel study of piroxicam versus indomethacin in the treatment of low back pain. Ann Clin Res. 1984;16(3):156–60.
CAS
PubMed
Google Scholar
Zerbini C, Ozturk ZE, Grifka J, Maini M, Nilganuwong S, Morales R, et al. Efficacy of etoricoxib 60 mg/day and diclofenac 150 mg/day in reduction of pain and disability in patients with chronic low back pain: results of a 4-week, multinational, randomized, double-blind study. Curr Med Res Opin. 2005;21(12):2037–49.
CAS
PubMed
Google Scholar
Hickey RF. Chronic low pack pain: a comparison of diflunisal with paracetamol. N Z Med J. 1982;95(707):312–4.
CAS
PubMed
Google Scholar
O’Donnell JB, Ekman EF, Spalding WM, Bhadra P, McCabe D, Berger MF. The effectiveness of a weak opioid medication versus a cyclo-oxygenase-2 (COX-2) selective non-steroidal anti-inflammatory drug in treating flare-up of chronic low-back pain: results from two randomized, double-blind, 6-week studies. J Int Med Res. 2009;37(6):1789–802.
PubMed
Google Scholar
Romanò CL, Romanò D, Bonora C, Mineo G. Pregabalin, celecoxib, and their combination for treatment of chronic low-back pain. J Orthop Traumatol. 2009;10(4):185–91.
PubMed
PubMed Central
Google Scholar
Koes BW, Backes D, Bindels PJE. Pharmacotherapy for chronic non-specific low back pain: current and future options. Expert Opin Pharmacother. 2018;19(6):537–45.
CAS
PubMed
Google Scholar
Moore RA, Chi CC, Wiffen PJ, Derry S, Rice ASC. Oral nonsteroidal anti-inflammatory drugs for neuropathic pain. Cochrane Database Syst Rev. 2015;2015(10):CD010902.
PubMed Central
Google Scholar
Shackelford S, Rauck R, Quessy S, Blum D, Hodge R, Philipson R. A randomized, double-blind, placebo-controlled trial of a selective COX-2 inhibitor, GW406381, in patients with postherpetic neuralgia. J Pain. 2009;10(6):654–60.
CAS
PubMed
Google Scholar
Vink R, Nechifor M. Magnesium in the central nervous system. Adelaide: University of Adelaide Press; 2011.
Google Scholar
Yousef AA, Al-Deeb AE. A double-blinded randomised controlled study of the value of sequential intravenous and oral magnesium therapy in patients with chronic low back pain with a neuropathic component. Anaesthesia. 2013;68(3):260–6.
CAS
PubMed
Google Scholar
Simon CB, Riley JL, Fillingim RB, Bishop MD, George SZ. Age group comparisons of TENS response among individuals with chronic axial low back pain. J Pain. 2015;16(12):1268–79.
PubMed
PubMed Central
Google Scholar
Pivec R, Stokes M, Chitnis AS, Paulino CB, Harwin SF, Mont MA. Clinical and economic impact of TENS in patients with chronic low back pain: analysis of a nationwide database. Orthopedics. 2013;36(12):922–8.
PubMed
Google Scholar
Garaud T, Gervais C, Szekely B, Michel-Cherqui M, Dreyfus JF, Fischler M. Randomized study of the impact of a therapeutic education program on patients suffering from chronic low-back pain who are treated with transcutaneous electrical nerve stimulation. Medicine (Baltimore). 2018;97(52):e13782.
Google Scholar
Jauregui JJ, Cherian JJ, Gwam CU, Chughtai M, Mistry JB, Elmallah RK, et al. A meta-analysis of transcutaneous electrical nerve stimulation for chronic low back pain. Surg Technol Int. 2016;28:296–302.
PubMed
Google Scholar
Wu LC, Weng PW, Chen CH, Huang YY, Tsuang YH, Chiang CJ. Literature review and meta-analysis of transcutaneous electrical nerve stimulation in treating chronic back pain. Reg Anesth Pain Med. 2018;43(4):425–33.
PubMed
PubMed Central
Google Scholar
Resende L, Merriwether E, Rampazo P, Dailey D, Embree J, Deberg J, et al. Meta-analysis of transcutaneous electrical nerve stimulation for relief of spinal pain. Eur J Pain. 2018;22(4):663–78.
CAS
PubMed
Google Scholar
Ferrándiz MEA, Nijs J, Gidron Y, Roussel N, Vanderstraeten R, van Dyck D, et al. Auto-targeted neurostimulation is not superior to placebo in chronic low back pain: a fourfold blind randomized clinical trial. Pain Physician. 2016;19(5):E707–19.
Google Scholar
Pivec R, Minshall ME, Mistry JB, Chughtai M, Elmallah RK, Mont MA. Decreased opioid utilization and cost at one year in chronic low back pain patients treated with transcutaneous electric nerve stimulation (TENS). Surg Technol Int. 2015;31(27):268–74.
Google Scholar
Baron R, Binder A, Attal N, Casale R, Dickenson AH, Treede RD. Neuropathic low back pain in clinical practice. Eur J Pain. 2016;20(6):861–73.
CAS
PubMed
PubMed Central
Google Scholar
Uhl RL, Roberts TT, Papaliodis DN, Mulligan MT, Dubin AH. Management of chronic musculoskeletal pain. J Am Acad Orthop Surg. 2014;22(2):101–10.
PubMed
Google Scholar
Morlion B. Pharmacotherapy of low back pain: targeting nociceptive and neuropathic pain components. Curr Med Res Opin. 2011;27(1):11–33.
CAS
PubMed
Google Scholar
Wagner T, Poole C, Roth-Daniek A. The capsaicin 8% patch for neuropathic pain in clinical practice: a retrospective analysis. Pain Med. 2013;14(8):1202–11.
PubMed
PubMed Central
Google Scholar
Mou J, Paillard F, Turnbull B, Trudeau J, Stoker M, Katz NP. Efficacy of Qutenza® (capsaicin) 8% patch for neuropathic pain: a meta-analysis of the qutenza clinical trials database. Pain. 2013;154(9):1632–9.
CAS
PubMed
Google Scholar
Argoff CE, Galer BS, Jensen MP, Oleka N, Gammaitoni AR. Effectiveness of the lidocaine patch 5% on pain qualities in three chronic pain states: assessment with the Neuropathic Pain Scale. Curr Med Res Opin. 2004;20(Suppl 2):S21–8.
CAS
PubMed
Google Scholar
Hashmi JA, Baliki MN, Huang L, Parks EL, Chanda ML, Schnitzer T, et al. Lidocaine patch (5%) is no more potent than placebo in treating chronic back pain when tested in a randomised double blind placebo controlled brain imaging study. Mol Pain. 2012;24(8):29.
Google Scholar
Baron R, Treede RD, Birklein F, Cegla T, Freynhagen R, Heskamp ML, et al. Treatment of painful radiculopathies with capsaicin 8% cutaneous patch. Curr Med Res Opin. 2017;33:1401–11.
CAS
PubMed
Google Scholar
Chrubasik S, Weiser T, Beime B. Effectiveness and safety of topical capsaicin cream in the treatment of chronic soft tissue pain. Phytother Res. 2010;24(12):1877–85.
CAS
PubMed
Google Scholar
Zis P, Bernali N, Argira E, Siafaka I, Vadalouca A. Effectiveness and impact of capsaicin 8% patch on quality of life in patients with lumbosacral pain: an open-label study. Pain Res Manag. 2019;2019:8346161.
PubMed
PubMed Central
Google Scholar