1. Neonatal Rotenone Administration Induces Psychiatric Disorder-Like Behavior and Changes in Mitochondrial Biogenesis and Synaptic Proteins in Adulthood

   • Amanda Siena
   • Jéssica Mayumi Camargo Yuzawa
   • Tatiana Rosado Rosenstock

   OriginalPaper 19 February 2021 Pages: 3015 - 3030

   

2. Role of Liver Growth Factor (LGF) in Parkinson’s Disease: Molecular Insights and Therapeutic Opportunities

   • Efthalia Angelopoulou
   • Yam Nath Paudel
   • Christina Piperi

   ReviewPaper 19 February 2021 Pages: 3031 - 3042

   

3. Retina and Brain Display Early and Differential Molecular and Cellular Changes in the 3xTg-AD Mouse Model of Alzheimer’s Disease

   • Ana Catarina Rodrigues-Neves
   • Rafael Carecho
   • António Francisco Ambrósio

   OriginalPaper 19 February 2021 Pages: 3043 - 3060

   

4. μ-Opioid Receptor–Mediated Enteric Glial Activation Is Involved in Morphine-Induced Constipation

   • Hui Gao
   • Yuxin Zhang
   • Qiang Wang

   OriginalPaper 23 February 2021 Pages: 3061 - 3070

   

5. Mitochondrial PKA Is Neuroprotective in a Cell Culture Model of Alzheimer’s Disease

   • Tania Das Banerjee
   • Kelly Reihl
   • Ruben K. Dagda

   OriginalPaper 23 February 2021 Pages: 3071 - 3083

   

6. Profiling of Serum Exosome MiRNA Reveals the Potential of a MiRNA Panel as Diagnostic Biomarker for Alzheimer’s Disease

   • Zhiwu Dong
   • Hongjun Gu
   • Kewen Zhao

   OriginalPaper 24 February 2021 Pages: 3084 - 3094

   

7. Mutant Ataxin-3–Containing Aggregates (MATAGGs) in Spinocerebellar Ataxia Type 3: Dynamics of the Disorder

   • Kritika Raj
   • Ravi Shankar Akundi

   ReviewPaper 24 February 2021 Pages: 3095 - 3118

   

8. Parkinson’s Disease–Associated LRRK2 Interferes with Astrocyte-Mediated Alpha-Synuclein Clearance

   • Linn Streubel-Gallasch
   • Veronica Giusti
   • Laura Civiero

   Original Article Open access 24 February 2021 Pages: 3119 - 3140

   

9. Remote Ischemic Postconditioning vs. Physical Exercise After Stroke: an Alternative Rehabilitation Strategy?

   • Xiaokun Geng
   • Qingzhu Wang
   • Yuchuan Ding

   OriginalPaper Open access 24 February 2021 Pages: 3141 - 3157

   

10. HDAC3 Downregulation Improves Cerebral Ischemic Injury via Regulation of the SDC1-Dependent JAK1/STAT3 Signaling Pathway Through miR-19a Upregulation

    • Hua Fang
    • Hua-Feng Li
    • Jian-Ping Zhang

    OriginalPaper 25 February 2021 Pages: 3158 - 3174

    

11. Collapsin response mediator protein 5 (CRMP5) modulates susceptibility to chronic social defeat stress in mice

    • Yu-Fen Lin
    • Kao Chin Chen
    • Ya-Hsin Hsiao

    OriginalPaper 26 February 2021 Pages: 3175 - 3186

    

12. Thioredoxin-1 Rescues MPP⁺/MPTP-Induced Ferroptosis by Increasing Glutathione Peroxidase 4

    • Liping Bai
    • Fang Yan
    • Jie Bai

    Original Article 26 February 2021 Pages: 3187 - 3197

    

13. Long Non-coding RNA GAS5 Worsens Coronary Atherosclerosis Through MicroRNA-194-3p/TXNIP Axis

    • Yanbing Li
    • Yu Geng
    • Lizhong Wang

    OriginalPaper Open access 27 February 2021 Pages: 3198 - 3207

    

14. Treadmill Exercise Alleviates Brain Iron Dyshomeostasis Accelerating Neuronal Amyloid-β Production, Neuronal Cell Death, and Cognitive Impairment in Transgenic Mice Model of Alzheimer’s Disease

    • Dong-Hun Choi
    • Ki-Chun Kwon
    • Joon-Yong Cho

    OriginalPaper 28 February 2021 Pages: 3208 - 3223

    

15. Metabolic Changes in Brain Slices over Time: a Multiplatform Metabolomics Approach

    • Carolina Gonzalez-Riano
    • Silvia Tapia-González
    • Coral Barbas

    Original Article 02 March 2021 Pages: 3224 - 3237

    

16. Intermittent Hypoxia Activates N-Methyl-D-Aspartate Receptors to Induce Anxiety Behaviors in a Mouse Model of Sleep-Associated Apnea

    • Yun Fan
    • Mei-Chuan Chou
    • Shiou-Lan Chen

    OriginalPaper 04 March 2021 Pages: 3238 - 3251

    

17. The Role of the Ubiquitin Proteasome System in Glioma: Analysis Emphasizing the Main Molecular Players and Therapeutic Strategies Identified in Glioblastoma Multiforme

    • Semer Maksoud

    ReviewPaper 04 March 2021 Pages: 3252 - 3269

    

18. Defective Mitochondrial Dynamics Underlie Manganese-Induced Neurotoxicity

    • Patricia Morcillo
    • Hector Cordero
    • Michael Aschner

    OriginalPaper 05 March 2021 Pages: 3270 - 3289

    

19. Roles and Mechanisms of Axon-Guidance Molecules in Alzheimer’s Disease

    • Lei Zhang
    • Zhipeng Qi
    • Yu Deng

    ReviewPaper 05 March 2021 Pages: 3290 - 3307

    

20. Small Non-coding RNAs Are Dysregulated in Huntington’s Disease Transgenic Mice Independently of the Therapeutic Effects of an Environmental Intervention

    • Celine Dubois
    • Geraldine Kong
    • Thibault Renoir

    OriginalPaper 06 March 2021 Pages: 3308 - 3318

    

21. Inflammatory and Oxidative Pathways Are New Drug Targets in Multiple Episode Schizophrenia and Leaky Gut, Klebsiella pneumoniae, and C1q Immune Complexes Are Additional Drug Targets in First Episode Schizophrenia

    • Michael Maes
    • Aristo Vojdani
    • Buranee Kanchanatawan

    OriginalPaper 06 March 2021 Pages: 3319 - 3334

    

22. High Genetic Addiction Risk Score (GARS) in Chronically Prescribed Severe Chronic Opioid Probands Attending Multi-pain Clinics: an Open Clinical Pilot Trial

    • Mark Moran
    • Kenneth Blum
    • Mark S. Gold

    OriginalPaper Open access 08 March 2021 Pages: 3335 - 3346

    

23. Divulging the Intricacies of Crosstalk Between NF-Kb and Nrf2-Keap1 Pathway in Neurological Complications of COVID-19

    • Ranjana Bhandari
    • Garima Khanna
    • Anurag Kuhad

    ReviewPaper 08 March 2021 Pages: 3347 - 3361

    

24. The LncRNA RP11-279C4.1 Enhances the Malignant Behaviour of Glioma Cells and Glioma Stem-Like Cells by Regulating the miR-1273g-3p/CBX3 Axis

    • Faming Wang
    • Le Zhang
    • Liudi Yuan

    OriginalPaper 10 March 2021 Pages: 3362 - 3373

    

25. Verapamil Prevents Development of Cognitive Impairment in an Aged Mouse Model of Sporadic Alzheimer’s Disease

    • Heba A. Ahmed
    • Saifudeen Ismael
    • Tauheed Ishrat

    OriginalPaper 11 March 2021 Pages: 3374 - 3387

    

26. Microglia Biomarkers in Alzheimer’s Disease

    • Peng-Fei Zhang
    • Hao Hu
    • Jin-Tai Yu

    ReviewPaper 12 March 2021 Pages: 3388 - 3404

    

27. Quinacrine and Niclosamide Promote Neurite Growth in Midbrain Dopaminergic Neurons Through the Canonical BMP-Smad Pathway and Protect Against Neurotoxin and α-Synuclein-Induced Neurodegeneration

    • Susan R. Goulding
    • Martin Lévesque
    • Gerard W. O’Keeffe

    OriginalPaper 12 March 2021 Pages: 3405 - 3416

    

28. Neurological Manifestation of SARS-CoV-2 Induced Inflammation and Possible Therapeutic Strategies Against COVID-19

    • Dipak Kumar
    • Sadaf Jahan
    • Mohammed Alaidarous

    ReviewPaper 14 March 2021 Pages: 3417 - 3434

    

29. Genetic Analysis of ZNF Protein Family Members for Early-Onset Parkinson’s Disease in Chinese Population

    • Chun Yu Li
    • Ru Wei Ou
    • Hui Fang Shang

    OriginalPaper 15 March 2021 Pages: 3435 - 3442

    

30. Metaplastic Effects of Ketamine and MK-801 on Glutamate Receptors Expression in Rat Medial Prefrontal Cortex and Hippocampus

    • Alessandro Piva
    • Lucia Caffino
    • Cristiano Chiamulera

    OriginalPaper Open access 15 March 2021 Pages: 3443 - 3456

    

31. Elevation of miR-146a Inhibits BTG2/BAX Expression to Ameliorate Postoperative Cognitive Dysfunction Following Probiotics (VSL#3) Treatment

    • Lei Mao
    • Qingcui Zeng
    • Min Xie

    OriginalPaper 16 March 2021 Pages: 3457 - 3470

    

32. Protective Effect of GM1 Attenuates Hippocampus and Cortex Apoptosis After Ketamine Exposure in Neonatal Rat via PI3K/AKT/GSK3β Pathway

    • Zhiheng Zhang
    • Wenhan Liu
    • Li Gao

    OriginalPaper 17 March 2021 Pages: 3471 - 3483

    

33. Visual Dysfunction in Multiple Sclerosis and its Animal Model, Experimental Autoimmune Encephalomyelitis: a Review

    • Taekyun Shin
    • Meejung Ahn
    • Moon-Doo Kim

    ReviewPaper 20 March 2021 Pages: 3484 - 3493

    

34. Stem Cell-Derived Exosomes: a New Strategy of Neurodegenerative Disease Treatment

    • Nashmin Fayazi
    • Mohsen Sheykhhasan
    • Rezvan Najafi

    ReviewPaper 21 March 2021 Pages: 3494 - 3514

    

35. Carotenoid Extract Derived from Euglena gracilis Overcomes Lipopolysaccharide-Induced Neuroinflammation in Microglia: Role of NF-κB and Nrf2 Signaling Pathways

    • Anna Piovan
    • Raffaella Filippini
    • Morena Zusso

    OriginalPaper Open access 21 March 2021 Pages: 3515 - 3528

    

36. PPM1F in Dentate Gyrus Modulates Anxiety-Related Behaviors by Regulating BDNF Expression via AKT/JNK/p-H3S10 Pathway

    • Fantao Meng
    • Jing Liu
    • Chen Li

    OriginalPaper 21 March 2021 Pages: 3529 - 3544

    

37. Assessment of the Effects of Stretch-Injury on Primary Rat Microglia

    • Mike Shaughness
    • Kimberly Byrnes

    OriginalPaper 24 March 2021 Pages: 3545 - 3560

    

38. Nervous System Involvement in COVID-19: a Review of the Current Knowledge

    • Mahnaz Norouzi
    • Paniz Miar
    • Parvaneh Nikpour

    ReviewPaper 25 March 2021 Pages: 3561 - 3574

    

39. Epigenetics Involvement in Oxaliplatin-Induced Potassium Channel Transcriptional Downregulation and Hypersensitivity

    • Vanessa Pereira
    • Sylvain Lamoine
    • Jérôme Busserolles

    OriginalPaper 26 March 2021 Pages: 3575 - 3587

    

40. Anti-brain Aging Effects of Small Molecule Inhibitor DDQ

    • Murali Vijayan
    • Chhanda Bose
    • P. Hemachandra Reddy

    OriginalPaper 26 March 2021 Pages: 3588 - 3600

    

41. Retraction Note: TWEAK-Fn14 Influences Neurogenesis Status via Modulating NF-κB in Mice with Spinal Cord Injury

    • Jing Xu
    • Jian He
    • Jian Xi

    Retraction Note 15 May 2021 Pages: 3601 - 3601

42. Retraction Note to: Effects of BDNF-Transfected BMSCs on Neural Functional Recovery and Synaptophysin Expression in Rats with Cerebral Infarction

    • Yongming Zhang
    • Binghui Qiu
    • Jiachuan Liu

    Retraction Note 28 May 2021 Pages: 3602 - 3602