1. Chemical and biological aspects of posaconazole as a classic antifungal agent with non-classical properties: highlighting a tetrahydrofuran-based drug toward generation of new drugs

   • Sakineh Dadashpour
   • Elham Ghobadi
   • Saeed Emami

   Review Article 19 May 2022 Pages: 833 - 850

   

2. Isoindolone derivatives as novel potential anti-Alzheimer’s candidates: synthesis, in silico, and AChE inhibitory activity evaluation

   • Erik Andrade-Jorge
   • Fernando Rivera-Sánchez
   • Adelfo Reyes-Ramírez

   Original Research 09 April 2022 Pages: 851 - 866

   

3. Discovery of novel donepezil-M30D hybrids with neuroprotective properties for Alzheimer’s disease treatment

   • Andrés F. Yepes
   • Camilo A. Ramírez
   • Rafael Posada-Duque

   Original Research 09 April 2022 Pages: 867 - 885

   

4. Novel norsufentanil analogues containing triazole ring; synthesis, radioligand binding assay, and pharmacological evaluation

   • Majid Nami
   • Peyman Salehi
   • Mehrdad Faizi

   Original Research 12 April 2022 Pages: 886 - 893

   

5. Evaluation of novel multifunctional organoselenium compounds as potential cholinesterase inhibitors against Alzheimer’s disease

   • Dina A. Refaay
   • Dalia M. Ahmed
   • Saad Shaaban

   Original Research 12 April 2022 Pages: 894 - 904

   

6. Design, synthesis of amide derivatives of scutellarin and their antileukemia and neuroprotective activities

   • Tong Han
   • Chunyu Jiang
   • Chenghao Jin

   Original Research 19 April 2022 Pages: 905 - 915

   

7. Hybrid molecules of scutellarein and 3, 5, 6-trimethylpyrazine-2-formic acid linked with polar amino acid for ischemic stroke

   • Shuxia Wu
   • Mingji Liu
   • Yongxi Dong

   Original Research 22 April 2022 Pages: 916 - 924

   

8. Synthesis, cytotoxicities, and carbonic anhydrase inhibition activities of pyrazoline–benzenesulfonamide derivatives harboring phenol/polyphenol moieties

   • Sinan Bilginer
   • Sanaa K. Bardaweel
   • Cavit Kazaz

   Original Research 23 April 2022 Pages: 925 - 935

   

9. Novel orthodiphenyl five-member N-heteroaromatic compounds as potent anticancer cell agents

   • Shijia Hu
   • Yunqi Li
   • Yihua Chen

   Original Research 27 April 2022 Pages: 936 - 948

   

10. Synthesis and antimycobacterial evaluation of fluoroquinolones derivatives coupled with isoprenyl moiety at the C-7 position

    • César A. Ribeiro
    • Dijovani B. dos Reis
    • Mauricio F. Saraiva

    Original Research 29 April 2022 Pages: 949 - 959

    

11. Dual HDAC–BRD4 inhibitors endowed with antitumor and antihyperalgesic activity

    • Soumia Maach
    • Niccolò Chiaramonte
    • Maria Novella Romanelli

    Original Research Open access 03 May 2022 Pages: 960 - 974

    

12. N-Substituted 4-sulfamoylbenzoic acid derivatives as inhibitors of cytosolic phospholipase A₂α

    • Daniel Borecki
    • Matthias Lehr

    Original Research Open access 05 May 2022 Pages: 975 - 992

    

13. Microwave-assisted synthesis and evaluation of their antiproliferative, antimicrobial, activities and DNA Binding studies of (3-Methyl-7H-furo[2,3-f]chromen-2-yl)(aryl)methanones

    • Ravinder Dharavath
    • M. Sarasija
    • Sreenu Daravath

    Original Research 05 May 2022 Pages: 993 - 1002

    

14. Synthesis and evaluation of new sartan derivatives

    • Bertsetseg Dalaijargal
    • Le Mi
    • Zhi-Long Chen

    Original Research 06 May 2022 Pages: 1003 - 1010

    

15. N-Phosphorylation of daunorubicin—synthetic approaches and antiproliferative properties of the products

    • Aleksandra A. Moiseeva
    • Oleg I. Artyushin
    • Valery K. Brel

    Original Research 06 May 2022 Pages: 1011 - 1025

    

16. Synthesis, in-vitro biological evaluation, and molecular docking study of novel spiro-β-lactam-isatin hybrids

    • Aliasghar Jarrahpour
    • Zahra Jowkar
    • Namık Özdemir

    Original Research 10 May 2022 Pages: 1026 - 1034

    

17. Design, synthesis, and biological evaluation of novel 2-acetylphenol-rivastigmine hybrids as potential multifunctional agents for the treatment of Alzheimer’s disease

    • Cong Deng
    • Jing Mi
    • Hui Li

    Original Research 14 May 2022 Pages: 1035 - 1048

    

18. Platanic acid derived amides are more cytotoxic than their corresponding oximes

    • Marie Kozubek
    • Sophie Hoenke
    • René Csuk

    Original Research Open access 16 May 2022 Pages: 1049 - 1059