A study of alkene disulfonoxylation Shyam SathyamoorthiSteven P. Kelley Original Research Article 28 May 2024
Exploring nucleoside analogs: key targets in the viral life cycle - advancing strategies against SARS-CoV-2 Roopal GargRaveen KumarRicha Srivastava Review Article 28 May 2024
Design and synthesis of benzo[d]imidazo-6,7-dihydrobenzo[d] imidazo[2,1-b]thiazol-8(5H)-ones as potent anti-infective agents Rakesh K. BollikandaYana L. EsaulkovaSrinivas Kantevari Original Research Article 28 May 2024
Design and synthesis of indole-based elipticine analogues as topoisomerase IIβ inhibitors Mardia T. El SayedAlaadin E. SarhanMamdouh M. Ali Original Research Article 28 May 2024
Discovery of cytotoxic truncated vitamin D derivatives against both bortezomib‐sensitive and bortezomib‐resistant multiple myeloma phenotypes Mohamed O. RadwanSawa SakaiMikako Fujita Original Research Article 24 May 2024
Correction: Bioassay-guided fractionations of Cannabis sativa extract and HPLC-assisted purifications of anti-proliferative active fractions lead to the isolation of 16 known and one new phytomolecule and their in-silico analysis Yedukondalu NalliSahil BhartiMahendra Kumar Verma Correction 22 May 2024
Morpholinated curcuminoids against urinary bladder cancer cells: synthesis and anticancer evaluation Pawel BakunMalgorzata KucinskaTomasz Goslinski Original Research Article Open access 22 May 2024
Structural simplification and ester bond flipping lead to bis-benzodioxole derivatives as potential hypolipidemic and hepatoprotective agent Yundong XieSiyao WangShipeng He Original Research Article 22 May 2024
Synthesis and in vitro biological activity of chalcone derivatives as potential antiparasitic agents Koketso J. SetshediRichard M. BeteckLesetja J. Legoabe Original Research Article Open access 21 May 2024
Discovery of HNPC-A188: a novel acaricide containing trifluoroethyl thioether and pyrimidin-4-amine Ting XiaoAiping LiuWeidong Liu Original Research Article 20 May 2024
The emergence of sulfo-click amidation in kinetic target-guided synthesis Prakash T. ParvatkarRoman Manetsch Review Article Open access 18 May 2024
Development of semisynthetic saponin immunostimulants Di BaiHyunjung KimPengfei Wang Review Article Open access 18 May 2024
A very promising antibiofilm activity against Candida albicans from an in vitro screening for antimicrobial, antibiofilm and antiproliferative activity of new synthesized 4-cinnamamido- and 2-phenoxyacedamido-1H-pyrazol-5-yl)benzamides Fabiana PlesciaValentina CataniaDomenico Schillaci Original Research Article Open access 15 May 2024
Candida albicans ergosterol disorders as a consequence of the new sulfone derivative action mode Monika StaniszewskaMichalina KazekZbigniew Ochal Original Research Article Open access 14 May 2024
Naturally occurring and artificially designed antimicrobial peptides: a comparative study of Mastoparan C and BP52 Hai Bui Thi PhuongYen Do HaiHuy Luong Xuan Brief Report 13 May 2024
Recent pharmacological insights about imidazole hybrids: a comprehensive review Samet PoyrazMetin YıldırımMehmet Ersatir Review Article 13 May 2024
Synthesis of novel benzothieno-[3,2’-f][1,3] oxazepines and their isomeric 2-oxo-2H-spiro[benzothiophene-3,3’-pyrrolines] via 1,4-dipolar cycloaddition reaction and their evaluation as cytotoxic anticancer leads Mohammed M. Al-MahadeenAreej M. JaberMutasem O. Taha Original Research Article 11 May 2024
Folate-conjugated organic CO prodrugs: Synthesis and CO release kinetic studies Shameer M. KondengadanShubham BansalBinghe Wang Original Research Article 10 May 2024
Structure-activity relationships and pharmacokinetic evaluation of L-cystine diamides as L-cystine crystallization inhibitors for cystinuria Longqin HuHaifa AlbanyanAmrik Sahota Original Research Article Open access 07 May 2024
Molecular hybridization method for obtaining paeonol-based fibrate derivatives with potent lipid-lowering and hepatoprotective activity Lina QuanYing GuoYundong Xie Original Research Article 06 May 2024
Role of natural secondary metabolites as HIF-1 inhibitors in cancer therapy Prem Shankar MishraRakhi MishraSamiksha Dewangan Review Article 02 May 2024
Characterization of the CO release properties of a common CO donor, CORM-401, in the context of its application in studying CO biology Nicola BauerQiyue MaoBinghe Wang Original Research Article 18 April 2024
Antitumor studies on celastrol and its derivatives as RORα agonists and RORγ inhibitors based on Alphafold reverse docking strategy Bangwen YueXiuli Wu Original Research Article 12 April 2024
Phenoxyalkyl cyclic and acyclic amine derivatives: what do they teach us about scaffold-based drug design? Mohammad Mahdi RezaeifarArdavan AbiriYaghoub Pourshojaei Review Article 10 April 2024
Synthesis and anticancer activity of novel coumarin-stilbene hybrids with different hydrocarbon chains as linkers Lamya A. Al-lehaibEhab M. M. AliReda M. El-Shishtawy Original Research Article 05 April 2024
Vital residues-orientated rational design of butenolide inhibitors targeting Of ChtI Qing HanYun-Jiang ZiHong-Xia Duan Brief Report 02 April 2024
Design, synthesis and antitumor activity evaluation of novel benzamide HDAC inhibitors Ci CaiYepeng Luan Original Research Article 28 March 2024
Design, synthesis, and in vitro biological evaluation of novel HDAC inhibitors bearing C-1 phenyl substituted tetrahydroisoquinoline Cap moiety as anti-tumor therapeutic agents Jie WangChi ZhouLei Liu Original Research Article 27 March 2024 Pages: 687 - 702
Diffractaic acid and its ethers as anti-respiratory syncytial virus agents Aleksandr S. FilimonovDiana U. IsmangulovaNariman F. Salakhutdinov Original Research Article 11 March 2024 Pages: 677 - 686
Synthesis, urease inhibitory and anticancer evaluation of glucosamine-sulfonylurea conjugates Ghadeer A. R. Y. SuaifanMayadah ShehadehMajid Khan Original Research Article 07 March 2024 Pages: 663 - 676
Motor and non-motor symptoms, drugs, and their mode of action in Parkinson’s disease (PD): a review Nancy SainiNeetu SinghHarvinder Singh Sohal Review Article 07 March 2024 Pages: 580 - 599
Evaluation of ortho-substituted Bis-Functionalized Triazoles as Tyrosinase Inhibitors: Modulating Dopamine Synthesis and Behavior in Zebrafish Shainaz LandgeJack PhilpVinoth Sittaramane Original Research Article 06 March 2024 Pages: 651 - 662
Bioassay-guided fractionations of Cannabis sativa extract and HPLC-assisted purifications of anti-proliferative active fractions lead to the isolation of 16 known and one new phytomolecule and their in-silico analysis Yedukondalu NalliSahil BhartiMahendra Kumar Verma Original Research Article 05 March 2024 Pages: 635 - 650
Design, synthesis, and biochemical and computational screening of novel oxindole derivatives as inhibitors of Aurora A kinase and SARS-CoV-2 spike/host ACE2 interaction Donatus B. EniJoel CasselFidele Ntie-Kang Original Research Article Open access 05 March 2024 Pages: 620 - 634
Evolution and challenges of opioids in pain management: Understanding mechanisms and exploring strategies for safer analgesics Toluwalope Temitope BakareHenrietta Onyinye UzoetoOlanrewaju Ayodeji Durojaye Review Article 29 February 2024 Pages: 563 - 579
Adenine derivatives as inhibitors of the casein kinase CK1delta enzyme Andrea SpinaciCatia LambertucciRosaria Volpini Original Research Article 28 February 2024 Pages: 611 - 619
Development of novel chalcone derivatives as multifunctional agents for the treatment of Alzheimer’s disease Xinjuan LiYuting LiZhipei Sang Original Research Article 26 February 2024 Pages: 548 - 561
2-Styrylchromones as inhibitors of α-amylase and α-glucosidase enzymes for the management of type 2 diabetes mellitus Clementina M. M. SantosCarina ProençaEduarda Fernandes Original Research Article Open access 24 February 2024 Pages: 600 - 610
Synthesis, characterization, and anticancer activity of syringaldehyde-derived chalcones against female cancers Qionghui PanHuamao YangFaqing Ye Original Research Article 19 February 2024 Pages: 532 - 547
Synthesis and pharmacological activities of Schiff bases with some transition metal complexes: a review Kibrom MezgebeEndale Mulugeta Review Article 19 February 2024 Pages: 439 - 463
The use of single-molecule FRET for the characterization of Holliday junctions containing human telomeric DNA: a methodological approach for nanoscale distance, mobility, and stability measurements Abeer F. R. AlanaziShozeb HaiderGary N. Parkinson Brief Report 19 February 2024
Targeting disease with benzoxazoles: a comprehensive review of recent developments Abdulrahman AbdullahiKeng Yoon Yeong Review Article Open access 18 February 2024 Pages: 406 - 438
Preliminary structure−activity relationships analysis on N-(3,5-dichlorophenyl)-4,5-dihydronaphtho[1,2-d]thiazol-2-amine, a disruptor of mycobacterial energetics Miriam GirardiniDiana MachadoMarco Pieroni Original Research Article 17 February 2024 Pages: 518 - 531
Insights on synthetic strategies and structure-activity relationship of donepezil and its derivatives Saraswati PatelSonika JainJaya Dwivedi Review Article 17 February 2024 Pages: 370 - 405
Identification of novel benzoyl hydrazine derivatives as activators of neddylation pathway to inhibit the tumor progression in vitro Xuan WangSumeng GuanMoran Sun Original Research Article 15 February 2024 Pages: 504 - 517
Selectivity of N(2)-substituted oxotriazinoindole aldose reductase inhibitors is determined by the interaction pattern with Pro301-Arg312 loop of aldehyde reductase Lucia KováčikováSunil GaikwadMilan Štefek Original Research Article Open access 14 February 2024 Pages: 492 - 503
Novel biologically active pyridine derivatives: Synthesis, structure characterization, in vitro antimicrobial evaluation and structure-activity relationship Mohamed A. ElsayedAlshaimaa M. ElsayedFarid M. Sroor Original Research Article Open access 14 February 2024 Pages: 476 - 491
Benzocaine-N-acylindoline conjugates: synthesis and antiviral activity against Coxsackievirus B3 Alexandrina S. VolobuevaAnton A. ShetnevSergey V. Baykov Original Research Article 13 February 2024 Pages: 464 - 475
Exploring the latest breakthroughs in rhodesain inhibitors for African trypanosomiasis Diego Eidy ChibaGuilherme Felipe dos Santos FernandesCauê Benito Scarim Review Article 02 February 2024 Pages: 354 - 369
Unveiling the potential of prodrug and drug-conjugate strategies in treatment of diabetes mellitus and its complications Neha V. BhilareRushikesh ShedgeAjinkya More Review Article 29 January 2024 Pages: 337 - 353
