Volume 377, Issue 4-6

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June 2008

Special Issue related to the 5th International Receptor Symposium

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36 articles in this issue

5th International Symposium on receptor mechanisms, signal transduction and drug effects
Shizuo Yamada
Fred J. Ehlert
Morley D. Hollenberg
Editorial 21 March 2008 Pages: 267 - 268
Candidate gene polymorphisms predicting individual sensitivity to opioids
Shinya Kasai
Masakazu Hayashida
Kazutaka Ikeda
Special Article 13 November 2007 Pages: 269 - 281
Brain angiotensin receptors and binding proteins
Robert C. Speth
Vardan T. Karamyan
Review 03 January 2008 Pages: 283 - 293
At the frontline of Alzheimer’s disease treatment: γ-secretase inhibitor/modulator mechanism
Taisuke Tomita
Review 24 November 2007 Pages: 295 - 300
Dopamine transporter mutant mice in experimental neuropharmacology
Raul R. Gainetdinov
Special Article 05 December 2007 Pages: 301 - 313
Prothymosin α plays a key role in cell death mode-switch, a new concept for neuroprotective mechanisms in stroke
Hiroshi Ueda
Review 05 January 2008 Pages: 315 - 323
The activation of transient receptor potential vanilloid receptor subtype 1 by capsaicin without extracellular Ca²⁺ is involved in the mechanism of distinct substance P release in cultured rat dorsal root ganglion neurons
He-Bin Tang
Yoshihiro Nakata
Original Article 23 November 2007 Pages: 325 - 332
Down-regulation of TRPM6-mediated magnesium influx by cyclosporin A
Akira Ikari
Chiaki Okude
Masao Miwa
Original Article 17 November 2007 Pages: 333 - 343
Epac: effectors and biological functions
Sara S. Roscioni
Carolina R. S. Elzinga
Martina Schmidt
Review 05 January 2008 Pages: 345 - 357
Adenylyl cyclase type 6 overexpression selectively enhances β-adrenergic and prostacyclin receptor-mediated inhibition of cardiac fibroblast function because of colocalization in lipid rafts
Xiaoqiu Liu
Muthusamy Thangavel
Rennolds S. Ostrom
Original Article 13 October 2007 Pages: 359 - 369
Acute inhibitory effect of dronedarone, a noniodinated benzofuran analogue of amiodarone, on Na⁺/Ca²⁺ exchange current in guinea pig cardiac ventricular myocytes
Yasuhide Watanabe
Junko Kimura
Original Article 08 April 2008 Pages: 371 - 376
Proteinases, proteinase-activated receptors (PARs) and the pathophysiology of cancer and diseases of the cardiovascular, musculoskeletal, nervous and gastrointestinal systems
Kristina K. Hansen
Katerina Oikonomopoulou
Morley D. Hollenberg
Review 19 October 2007 Pages: 377 - 392
A novel mechanism of mechanical stress-induced angiotensin II type 1–receptor activation without the involvement of angiotensin II
Noritaka Yasuda
Hiroshi Akazawa
Issei Komuro
Review 29 November 2007 Pages: 393 - 399
Impairment of endothelium-dependent ACh-induced relaxation in aorta of diabetic db/db mice—possible dysfunction of receptor and/or receptor–G protein coupling
Tomohiro Miike
Kazuyoshi Kunishiro
Hiroaki Shirahase
Original Article 29 January 2008 Pages: 401 - 410
A selective T-type Ca²⁺ channel blocker R(−) efonidipine
Min-Chul Shin
Chang-Ju Kim
Norio Akaike
Original Article 16 February 2008 Pages: 411 - 421
Misinterpretation of the effect of amlodipine on cytosolic calcium concentration with fura-2 fluorospectrometry
Masayoshi Asai
Kazuhiko Takeuchi
Hiroshi Watanabe
Original Article 29 January 2008 Pages: 423 - 427
Effect of P2 receptor on the intracellular calcium increase by cancer cells in human umbilical vein endothelial cells
Namie Nejime
Naoko Tanaka
Kazumasa Shinozuka
Original Article 22 January 2008 Pages: 429 - 436
Therapeutic receptor targets for lower urinary tract dysfunction
Naoki Yoshimura
Yasuhiro Kaiho
Pradeep Tyagi
Review 21 November 2007 Pages: 437 - 448
Signal transduction underlying the control of urinary bladder smooth muscle tone by muscarinic receptors and β-adrenoceptors
Elfaridah P. Frazier
Stephan L. M. Peters
Martin C. Michel
Review Open access 04 December 2007 Pages: 449 - 462
In vivo characterization of muscarinic receptors in peripheral tissues: evaluation of bladder selectivity of anticholinergic agents to treat overactive bladder
Shuji Maruyama
Naoki Hasuike
Shizuo Yamada
Original Article 12 December 2007 Pages: 463 - 471
Expression and functional role of β-adrenoceptors in the human urinary bladder urothelium
Atsushi Otsuka
Hitoshi Shinbo
Seiichiro Ozono
Original Article 01 March 2008 Pages: 473 - 481
Therapeutic effects of the putative P2X₃/P2X_2/3 antagonist A-317491 on cyclophosphamide-induced cystitis in rats
Katsuaki Ito
Akihito Iwami
Masahiro Ikeda
Original Article 05 October 2007 Pages: 483 - 490
Does anticholinergic medication have a role in treating men with overactive bladder and benign prostatic hyperplasia?
Kyu-Sung Lee
Hye Won Lee
Deok Hyun Han
Review 03 January 2008 Pages: 491 - 501
Muscarinic receptor subtypes involved in carbachol-induced contraction of mouse uterine smooth muscle
Takio Kitazawa
Ryuichi Hirama
Tetsuro Taneike
Original Article 11 December 2007 Pages: 503 - 513
Cloning and characterization of the rat free fatty acid receptor GPR120: in vivo effect of the natural ligand on GLP-1 secretion and proliferation of pancreatic β cells
Toshiki Tanaka
Takeaki Yano
Gozoh Tsujimoto
Original Article 05 March 2008 Pages: 515 - 522
Free fatty acids induce cholecystokinin secretion through GPR120
Toshiki Tanaka
Susumu Katsuma
Gozoh Tsujimoto
Original Article 31 October 2007 Pages: 523 - 527
Mediation of β-endorphin in andrographolide-induced plasma glucose-lowering action in type I diabetes-like animals
Bu Chin Yu
Cheng Kuei Chang
Juei Tang Cheng
Original Article 15 December 2007 Pages: 529 - 540
Peroxisome proliferator activated receptor γ and oxidized docosahexaenoic acids as new class of ligand
Toshimasa Itoh
Keiko Yamamoto
Review 08 January 2008 Pages: 541 - 547
On the analysis of ligand-directed signaling at G protein-coupled receptors
Frederick J. Ehlert
Review 06 February 2008 Pages: 549 - 577
Structure-activity relationship of vasoactive intestinal peptide (VIP): potent agonists and potential clinical applications
Satomi Onoue
Shingen Misaka
Shizuo Yamada
Review 03 January 2008 Pages: 579 - 590
Cordycepin (3′-deoxyadenosine) inhibits the growth of B16-BL6 mouse melanoma cells through the stimulation of adenosine A₃ receptor followed by glycogen synthase kinase-3β activation and cyclin D₁ suppression
Noriko Yoshikawa
Shizuo Yamada
Kazuki Nakamura
Original Article 15 December 2007 Pages: 591 - 595
Transcriptional regulation of human UGT1A1 gene expression through distal and proximal promoter motifs: implication of defects in the UGT1A1 gene promoter
Junko Sugatani
Kousuke Mizushima
Masao Miwa
Original Article 03 January 2008 Pages: 597 - 605
Ab initio fragment molecular orbital study of ligand binding to human progesterone receptor ligand-binding domain
Takanori Harada
Kenji Yamagishi
Hiroaki Tokiwa
Original Article 11 March 2008 Pages: 607 - 615
Recent progresses in the experimental methods and evaluation strategies of transporter functions for the prediction of the pharmacokinetics in humans
Satoshi Kitamura
Kazuya Maeda
Yuichi Sugiyama
Special Article 07 June 2008 Pages: 617 - 628
Effects of ursodeoxycholic acid on the pharmacokinetics and pharmacodynamics of intravenous and oral midazolam in healthy volunteers
Dongmei Yan
Yingbao Yang
Hiroshi Watanabe
Original Article 19 December 2007 Pages: 629 - 636
Pharmacokinetics and pharmacodynamics of erythropoietin receptor in healthy volunteers
Wojciech Krzyzanski
Elzbieta Wyska
Original Article 11 December 2007 Pages: 637 - 645

Volume 377, Issue 4-6

5th International Symposium on receptor mechanisms, signal transduction and drug effects

Candidate gene polymorphisms predicting individual sensitivity to opioids

Brain angiotensin receptors and binding proteins

At the frontline of Alzheimer’s disease treatment: γ-secretase inhibitor/modulator mechanism

Dopamine transporter mutant mice in experimental neuropharmacology

Prothymosin α plays a key role in cell death mode-switch, a new concept for neuroprotective mechanisms in stroke

The activation of transient receptor potential vanilloid receptor subtype 1 by capsaicin without extracellular Ca²⁺ is involved in the mechanism of distinct substance P release in cultured rat dorsal root ganglion neurons

Down-regulation of TRPM6-mediated magnesium influx by cyclosporin A

Epac: effectors and biological functions

Adenylyl cyclase type 6 overexpression selectively enhances β-adrenergic and prostacyclin receptor-mediated inhibition of cardiac fibroblast function because of colocalization in lipid rafts

Acute inhibitory effect of dronedarone, a noniodinated benzofuran analogue of amiodarone, on Na⁺/Ca²⁺ exchange current in guinea pig cardiac ventricular myocytes

Proteinases, proteinase-activated receptors (PARs) and the pathophysiology of cancer and diseases of the cardiovascular, musculoskeletal, nervous and gastrointestinal systems

A novel mechanism of mechanical stress-induced angiotensin II type 1–receptor activation without the involvement of angiotensin II

Impairment of endothelium-dependent ACh-induced relaxation in aorta of diabetic db/db mice—possible dysfunction of receptor and/or receptor–G protein coupling

A selective T-type Ca²⁺ channel blocker R(−) efonidipine

Misinterpretation of the effect of amlodipine on cytosolic calcium concentration with fura-2 fluorospectrometry

Effect of P2 receptor on the intracellular calcium increase by cancer cells in human umbilical vein endothelial cells

Therapeutic receptor targets for lower urinary tract dysfunction

Signal transduction underlying the control of urinary bladder smooth muscle tone by muscarinic receptors and β-adrenoceptors

In vivo characterization of muscarinic receptors in peripheral tissues: evaluation of bladder selectivity of anticholinergic agents to treat overactive bladder

Expression and functional role of β-adrenoceptors in the human urinary bladder urothelium

Therapeutic effects of the putative P2X₃/P2X_2/3 antagonist A-317491 on cyclophosphamide-induced cystitis in rats

Does anticholinergic medication have a role in treating men with overactive bladder and benign prostatic hyperplasia?

Muscarinic receptor subtypes involved in carbachol-induced contraction of mouse uterine smooth muscle

Cloning and characterization of the rat free fatty acid receptor GPR120: in vivo effect of the natural ligand on GLP-1 secretion and proliferation of pancreatic β cells

Free fatty acids induce cholecystokinin secretion through GPR120

Mediation of β-endorphin in andrographolide-induced plasma glucose-lowering action in type I diabetes-like animals

Peroxisome proliferator activated receptor γ and oxidized docosahexaenoic acids as new class of ligand

On the analysis of ligand-directed signaling at G protein-coupled receptors

Structure-activity relationship of vasoactive intestinal peptide (VIP): potent agonists and potential clinical applications

Cordycepin (3′-deoxyadenosine) inhibits the growth of B16-BL6 mouse melanoma cells through the stimulation of adenosine A₃ receptor followed by glycogen synthase kinase-3β activation and cyclin D₁ suppression

Transcriptional regulation of human UGT1A1 gene expression through distal and proximal promoter motifs: implication of defects in the UGT1A1 gene promoter

Ab initio fragment molecular orbital study of ligand binding to human progesterone receptor ligand-binding domain

Recent progresses in the experimental methods and evaluation strategies of transporter functions for the prediction of the pharmacokinetics in humans

Effects of ursodeoxycholic acid on the pharmacokinetics and pharmacodynamics of intravenous and oral midazolam in healthy volunteers

Pharmacokinetics and pharmacodynamics of erythropoietin receptor in healthy volunteers

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