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Tissue Engineering and Regenerative Medicine in Iran: Current State of Research and Future Outlook

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Abstract

During two decades ago, Iran has exhibited remarkable increase in scientific publication in different aspects including tissue engineering and regenerative medicine (TERM). The field of TERM in Iran dates comes back to the early part of the 1990 and the advent of stem cell researches. Nowadays, Iran is one of the privileged countries in stem cell therapy in the Middle East. The next major milestone in TERM was application and fabrication of scaffolds for tissue engineering in the early 2000s with a focus on engineering bone and cartilage tissue. A good amount of thoughtful works has also yielded prototypes of other tissue substitutes such as nerve conduits, liver, and even heart. However, forward movement to clinical application of these products is still far from offering clinically acceptable solutions. In this study, we have presented a comprehensive review on the efforts of Iranian scientists in different issues of tissue engineering and regenerative medicine field.

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Acknowledgments

We would like to thank the Iranian council for stem cell research and technology development for financial support. Because of space restrictions, we could not cite all studies. Therefore, we hereby extend our sincere apologies to these honorable investigators.

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The authors declare no potential conflicts of interest.

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    Authors and Affiliations

    1. Department of Tissue Engineering, Reproductive Biotechnology Research Center, Avicenna Research Institute, ACECR, P.O.Box: 19615-1177, Tehran, Iran

      Sahba Mobini, Manijeh Khanmohammadi, Hamed Heidari-Vala & Somaieh Kazemnejad

    2. Cellular and Molecular Research Center, Iran University of Medical Sciences, Tehran, Iran

      Ali Samadikuchaksaraei

    3. Department of Tissue Engineering and Regenerative Medicine, Faculty of Advanced Technologies in Medicine, Iran University of Medical Sciences, Tehran, Iran

      Ali Samadikuchaksaraei

    4. Division of Surgery and Radiology, Department of Clinical Science, School of Veterinary Medicine, Shiraz University, Shiraz, Iran

      Ali Moshiri

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    1. Sahba Mobini
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    Correspondence to Somaieh Kazemnejad.

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    The authors Sahba Mobini and Manijeh Khanmohammadi have contributed equally to the manuscript.

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    Mobini, S., Khanmohammadi, M., Heidari-Vala, H. et al. Tissue Engineering and Regenerative Medicine in Iran: Current State of Research and Future Outlook. Mol Biotechnol 57, 589–605 (2015). https://doi.org/10.1007/s12033-015-9865-2

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