1. 5th International Symposium on receptor mechanisms, signal transduction and drug effects

   • Shizuo Yamada
   • Fred J. Ehlert
   • Morley D. Hollenberg

   Editorial 21 March 2008 Pages: 267 - 268

   

2. Candidate gene polymorphisms predicting individual sensitivity to opioids

   • Shinya Kasai
   • Masakazu Hayashida
   • Kazutaka Ikeda

   Special Article 13 November 2007 Pages: 269 - 281

   

3. Brain angiotensin receptors and binding proteins

   • Robert C. Speth
   • Vardan T. Karamyan

   Review 03 January 2008 Pages: 283 - 293

   

4. At the frontline of Alzheimer’s disease treatment: γ-secretase inhibitor/modulator mechanism

   • Taisuke Tomita

   Review 24 November 2007 Pages: 295 - 300

   

5. Dopamine transporter mutant mice in experimental neuropharmacology

   • Raul R. Gainetdinov

   Special Article 05 December 2007 Pages: 301 - 313

6. Prothymosin α plays a key role in cell death mode-switch, a new concept for neuroprotective mechanisms in stroke

   • Hiroshi Ueda

   Review 05 January 2008 Pages: 315 - 323

   

7. The activation of transient receptor potential vanilloid receptor subtype 1 by capsaicin without extracellular Ca²⁺ is involved in the mechanism of distinct substance P release in cultured rat dorsal root ganglion neurons

   • He-Bin Tang
   • Yoshihiro Nakata

   Original Article 23 November 2007 Pages: 325 - 332

   

8. Down-regulation of TRPM6-mediated magnesium influx by cyclosporin A

   • Akira Ikari
   • Chiaki Okude
   • Masao Miwa

   Original Article 17 November 2007 Pages: 333 - 343

   

9. Epac: effectors and biological functions

   • Sara S. Roscioni
   • Carolina R. S. Elzinga
   • Martina Schmidt

   Review 05 January 2008 Pages: 345 - 357

   

10. Adenylyl cyclase type 6 overexpression selectively enhances β-adrenergic and prostacyclin receptor-mediated inhibition of cardiac fibroblast function because of colocalization in lipid rafts

    • Xiaoqiu Liu
    • Muthusamy Thangavel
    • Rennolds S. Ostrom

    Original Article 13 October 2007 Pages: 359 - 369

    

11. Acute inhibitory effect of dronedarone, a noniodinated benzofuran analogue of amiodarone, on Na⁺/Ca²⁺ exchange current in guinea pig cardiac ventricular myocytes

    • Yasuhide Watanabe
    • Junko Kimura

    Original Article 08 April 2008 Pages: 371 - 376

    

12. Proteinases, proteinase-activated receptors (PARs) and the pathophysiology of cancer and diseases of the cardiovascular, musculoskeletal, nervous and gastrointestinal systems

    • Kristina K. Hansen
    • Katerina Oikonomopoulou
    • Morley D. Hollenberg

    Review 19 October 2007 Pages: 377 - 392

    

13. A novel mechanism of mechanical stress-induced angiotensin II type 1–receptor activation without the involvement of angiotensin II

    • Noritaka Yasuda
    • Hiroshi Akazawa
    • Issei Komuro

    Review 29 November 2007 Pages: 393 - 399

    

14. Impairment of endothelium-dependent ACh-induced relaxation in aorta of diabetic db/db mice—possible dysfunction of receptor and/or receptor–G protein coupling

    • Tomohiro Miike
    • Kazuyoshi Kunishiro
    • Hiroaki Shirahase

    Original Article 29 January 2008 Pages: 401 - 410

    

15. A selective T-type Ca²⁺ channel blocker R(−) efonidipine

    • Min-Chul Shin
    • Chang-Ju Kim
    • Norio Akaike

    Original Article 16 February 2008 Pages: 411 - 421

    

16. Misinterpretation of the effect of amlodipine on cytosolic calcium concentration with fura-2 fluorospectrometry

    • Masayoshi Asai
    • Kazuhiko Takeuchi
    • Hiroshi Watanabe

    Original Article 29 January 2008 Pages: 423 - 427

    

17. Effect of P2 receptor on the intracellular calcium increase by cancer cells in human umbilical vein endothelial cells

    • Namie Nejime
    • Naoko Tanaka
    • Kazumasa Shinozuka

    Original Article 22 January 2008 Pages: 429 - 436

    

18. Therapeutic receptor targets for lower urinary tract dysfunction

    • Naoki Yoshimura
    • Yasuhiro Kaiho
    • Pradeep Tyagi

    Review 21 November 2007 Pages: 437 - 448

    

19. Signal transduction underlying the control of urinary bladder smooth muscle tone by muscarinic receptors and β-adrenoceptors

    • Elfaridah P. Frazier
    • Stephan L. M. Peters
    • Martin C. Michel

    Review Open access 04 December 2007 Pages: 449 - 462

    

20. In vivo characterization of muscarinic receptors in peripheral tissues: evaluation of bladder selectivity of anticholinergic agents to treat overactive bladder

    • Shuji Maruyama
    • Naoki Hasuike
    • Shizuo Yamada

    Original Article 12 December 2007 Pages: 463 - 471

    

21. Expression and functional role of β-adrenoceptors in the human urinary bladder urothelium

    • Atsushi Otsuka
    • Hitoshi Shinbo
    • Seiichiro Ozono

    Original Article 01 March 2008 Pages: 473 - 481

    

22. Therapeutic effects of the putative P2X₃/P2X_2/3 antagonist A-317491 on cyclophosphamide-induced cystitis in rats

    • Katsuaki Ito
    • Akihito Iwami
    • Masahiro Ikeda

    Original Article 05 October 2007 Pages: 483 - 490

    

23. Does anticholinergic medication have a role in treating men with overactive bladder and benign prostatic hyperplasia?

    • Kyu-Sung Lee
    • Hye Won Lee
    • Deok Hyun Han

    Review 03 January 2008 Pages: 491 - 501

24. Muscarinic receptor subtypes involved in carbachol-induced contraction of mouse uterine smooth muscle

    • Takio Kitazawa
    • Ryuichi Hirama
    • Tetsuro Taneike

    Original Article 11 December 2007 Pages: 503 - 513

    

25. Cloning and characterization of the rat free fatty acid receptor GPR120: in vivo effect of the natural ligand on GLP-1 secretion and proliferation of pancreatic β cells

    • Toshiki Tanaka
    • Takeaki Yano
    • Gozoh Tsujimoto

    Original Article 05 March 2008 Pages: 515 - 522

    

26. Free fatty acids induce cholecystokinin secretion through GPR120

    • Toshiki Tanaka
    • Susumu Katsuma
    • Gozoh Tsujimoto

    Original Article 31 October 2007 Pages: 523 - 527

    

27. Mediation of β-endorphin in andrographolide-induced plasma glucose-lowering action in type I diabetes-like animals

    • Bu Chin Yu
    • Cheng Kuei Chang
    • Juei Tang Cheng

    Original Article 15 December 2007 Pages: 529 - 540

    

28. Peroxisome proliferator activated receptor γ and oxidized docosahexaenoic acids as new class of ligand

    • Toshimasa Itoh
    • Keiko Yamamoto

    Review 08 January 2008 Pages: 541 - 547

    

29. On the analysis of ligand-directed signaling at G protein-coupled receptors

    • Frederick J. Ehlert

    Review 06 February 2008 Pages: 549 - 577

    

30. Structure-activity relationship of vasoactive intestinal peptide (VIP): potent agonists and potential clinical applications

    • Satomi Onoue
    • Shingen Misaka
    • Shizuo Yamada

    Review 03 January 2008 Pages: 579 - 590

    

31. Cordycepin (3′-deoxyadenosine) inhibits the growth of B16-BL6 mouse melanoma cells through the stimulation of adenosine A₃ receptor followed by glycogen synthase kinase-3β activation and cyclin D₁ suppression

    • Noriko Yoshikawa
    • Shizuo Yamada
    • Kazuki Nakamura

    Original Article 15 December 2007 Pages: 591 - 595

    

32. Transcriptional regulation of human UGT1A1 gene expression through distal and proximal promoter motifs: implication of defects in the UGT1A1 gene promoter

    • Junko Sugatani
    • Kousuke Mizushima
    • Masao Miwa

    Original Article 03 January 2008 Pages: 597 - 605

    

33. Ab initio fragment molecular orbital study of ligand binding to human progesterone receptor ligand-binding domain

    • Takanori Harada
    • Kenji Yamagishi
    • Hiroaki Tokiwa

    Original Article 11 March 2008 Pages: 607 - 615

    

34. Recent progresses in the experimental methods and evaluation strategies of transporter functions for the prediction of the pharmacokinetics in humans

    • Satoshi Kitamura
    • Kazuya Maeda
    • Yuichi Sugiyama

    Special Article 07 June 2008 Pages: 617 - 628

    

35. Effects of ursodeoxycholic acid on the pharmacokinetics and pharmacodynamics of intravenous and oral midazolam in healthy volunteers

    • Dongmei Yan
    • Yingbao Yang
    • Hiroshi Watanabe

    Original Article 19 December 2007 Pages: 629 - 636

    

36. Pharmacokinetics and pharmacodynamics of erythropoietin receptor in healthy volunteers

    • Wojciech Krzyzanski
    • Elzbieta Wyska

    Original Article 11 December 2007 Pages: 637 - 645