The glucose transporter GLUT12, a new actor in obesity and cancer Miguel BurgosEva Gil-IturbeM. Pilar Lostao Review Open access 10 May 2024
The role of exosome derived miRNAs in inter-cell crosstalk among insulin-related organs in type 2 diabetes mellitus Ting LuYing ZhengChengfu Yuan Review 03 May 2024
Role of microRNA-363 during tumor progression and invasion Arya Nasimi ShadIman AkhlaghipourMeysam Moghbeli Review 01 May 2024
Progress in extracellular vesicle homeostasis as it relates to cardiovascular diseases Yunan KangWenqian WuXiaodong Cui Review 30 April 2024
MicroRNAs from edible plants reach the human gastrointestinal tract and may act as potential regulators of gene expression Ester Díez-SainzFermín I. MilagroSilvia Lorente-Cebrián Original Article Open access 25 April 2024
Ovalbumin promotes innate immune response of Caenorhabditis elegans through DAF-16 and SKN-1 pathways in insulin/IGF-1 signaling Haibing PeiZhiyin LinJinyan Gao Research 18 April 2024
Fasting and fasting-mimicking conditions in the cancer immunotherapy era Ruben PioYaiza SenentDaniel Ajona Review Open access 08 April 2024
NCS-1 protein regulates TRPA1 channel through the PI3K pathway in breast cancer and neuronal cells Julio C. SánchezAlexander AlemánBarbara E. Ehrlich Original Article Open access 02 April 2024 Pages: 451 - 463
Sorcin promotes proliferation of hepatocellular carcinoma by regulating VEGFA/B via PI3K pathway Huan ZhangShanshan HuJun Zhang Original Article 27 March 2024 Pages: 381 - 392
Effect of chronic cold stress on gut microbial diversity, intestinal inflammation and pyroptosis in mice Hongming LvShijie XiaShize Li Research 25 March 2024 Pages: 465 - 477
MicroRNA-126 (MiR-126): key roles in related diseases Li LiaoYan TangXiaochun Zhang Review 22 March 2024 Pages: 277 - 286
Naturally occurring small molecules with dual effect upon inflammatory signaling pathways and endoplasmic reticulum stress response Daniela Correia da SilvaPatrícia ValentãoDavid M. Pereira Original Article Open access 19 March 2024 Pages: 421 - 437
Sexual dimorphism in thermogenic regulators and metrnl expression in adipose tissue of offspring mice exposed to maternal and postnatal overnutrition Zhao YangJianan JiangZhen Han Original Article 16 March 2024 Pages: 407 - 420
Integrated clinical and prognostic analyses of mTOR/Hippo pathway core genes in hepatocellular carcinoma Tianhang FengPing ChenYutong Yao Original Article Open access 12 March 2024 Pages: 439 - 449
Itaconate inhibits corticosterone-induced necroptosis and neuroinflammation via up-regulating menin in HT22 cells Jin-Yu LiangShan GaoYi-Yun Tang Original Article 01 March 2024 Pages: 393 - 405
Sialic acids cleavage induced by elastin-derived peptides impairs the interaction between insulin and its receptor in adipocytes 3T3-L1 Alexandre GuillotKevin ToussaintSébastien Blaise Original Article 23 February 2024 Pages: 363 - 379
Lactate ameliorates palmitate-induced impairment of differentiative capacity in C2C12 cells through the activation of voltage-gated calcium channels Juan WanChunfang ChengLi-Hua Yao Original Article 19 February 2024 Pages: 349 - 362
Novel insight on IRE1 in the regulation of chondrocyte dedifferentiation through ER stress independent pathway Young Seok EomFahad Hassan ShahSong Ja Kim Original Article 10 February 2024 Pages: 337 - 347
The role of PKM2 in cancer progression and its structural and biological basis Bingxin WuZuhui LiangCaiyan Wang Review 08 February 2024 Pages: 261 - 275
PGC-1α activation boosts exercise-dependent cellular response in the skeletal muscle Soroosh MozaffaritabarErika KoltaiZsolt Radák Original Article Open access 23 January 2024 Pages: 329 - 335
Exercise-induced changes in plasma S-Klotho levels are associated with the obtained enhancements of heart rate variability in sedentary middle-aged adults: the FIT-AGEING study Ginés Navarro-LomasAbel Plaza-FloridoFrancisco J. Amaro-Gahete Original Article 04 January 2024 Pages: 317 - 328
Lactate coordinated with exercise promoted the browning of inguinal white adipose tissue Xuefei ChenYanjun LiJing Zhang Original Article 04 January 2024 Pages: 303 - 315
An experimental model of western diet in female Wistar rats leads to cardiac hypoxia related to a stimulated contractility Jean-Paul RigaudièreChrystèle JouveLuc Demaison Original Article 04 January 2024 Pages: 287 - 302
N6-methyladenosine in myeloid cells: a novel regulatory factor for inflammation-related diseases Jin PangTong-dong KuangKai Yin Review 30 December 2023 Pages: 249 - 260
Effects of exercise, metformin, and combination treatments on type 2 diabetic mellitus-induced muscle atrophy in db/db mice: Crosstalk between autophagy and the proteasome Mengqi XiangXinmeng YuanJiao Lu Original Article 19 December 2023 Pages: 235 - 247
ERG mediates the inhibition of NK cell cytotoxicity through the HLX/STAT4/Perforin signaling pathway, thereby promoting the progression of myocardial infarction Liang GuoDi WuYuan Gao Original Article 13 December 2023 Pages: 219 - 233
Exosomes derived from adipose tissues accelerate fibroblasts and keratinocytes proliferation and cutaneous wound healing via miR-92a/Hippo-YAP axis Zifei ShaoJinghao XuKun Li Original Article 02 December 2023 Pages: 189 - 204
Caveolin-1 deficiency alleviates palmitate-induced intracellular lipid accumulation and inflammation in pancreatic β cells Wen ZengNan CaiLongyi Zeng Original Article 30 November 2023 Pages: 175 - 188
Deciphering the roles of triiodothyronine (T3) and thyroid-stimulating hormone (TSH) on cardiac electrical remodeling in clinical and experimental hypothyroidism Oscar CasisLeire EcheazarraMónica Gallego Review Open access 29 November 2023 Pages: 1 - 9
Diet-inducing hypercholesterolemia show decreased O-GlcNAcylation of liver proteins through modulation of AMPK Sanjana JagannathSmitha Honnalagere MallannaC. D. Nandini Original Article 24 November 2023 Pages: 205 - 218
Isoliquiritigenin in combination with visceral adipose tissue and related markers as a predictive tool for nonalcoholic fatty liver disease Paola Mogna-PeláezAna Romo-HualdeM. Angeles Zulet Original Article Open access 24 November 2023
Quercetin improved hepatic circadian rhythm dysfunction in middle-aged mice fed with vitamin D-deficient diet Rui LiGuiping WangZhongxiao Wan Original Article 10 November 2023 Pages: 137 - 147
Single anastomosis duodeno-ileal bypass with sleeve gastrectomy generates sustained improvement of glycemic control compared with sleeve gastrectomy in the diet-induced obese rat model Sara BecerrilJavier A. CienfuegosGema Frühbeck Original Article Open access 07 November 2023 Pages: 149 - 160
Trimethylamine N-oxide promotes oxidative stress and lipid accumulation in macrophage foam cells via the Nrf2/ABCA1 pathway ZhiSheng LuoXiaoChen YuXiuRu Guan Original Article 07 November 2023 Pages: 67 - 79
Effects of resistance training on heat shock response (HSR), HSP70 expression, oxidative stress, inflammation, and metabolism in middle-aged people Carlos Henrique de Lemos MullerHelena Trevisan SchroederMauricio Krause Original Article 06 November 2023 Pages: 161 - 173
Parkin depletion prevents the age-related alterations in the FGF21 system and the decline in white adipose tissue thermogenic function in mice Alejandro Delgado-AnglésAlbert Blasco-RosetJoan Villarroya Original Article Open access 02 November 2023 Pages: 41 - 51
The effect of aspartame on accelerating caspase-dependent apoptosis of pancreatic islet via ZIPK/STAT3/caspase 3 signaling pathway Haiying HuPianhong ZhangHuilan Guo Original Article 31 October 2023 Pages: 53 - 65
High fat diet-induced downregulation of TRPV2 mediates hepatic steatosis via p21 signalling Pengfei WeiLixuan LiJing Guo Original Article 26 October 2023 Pages: 113 - 126
Fatty liver index (FLI): more than a marker of hepatic steatosis Anastasiya M. KanevaEvgeny R. Bojko Review 25 October 2023 Pages: 11 - 26
Frontiers in fatty liver: recent advances in pathogenic mechanisms, assessment of patients’ prognosis and pharmacotherapy Maite G. Fernández-BarrenaMatías A. Avila Editorial 21 October 2023 Pages: 811 - 813
Silencing suppressor of cytokine signaling 3 induces apoptosis and activates the p-STAT3/NF-κB pathway in hypoxic cultivated H9c2 cells Qiang GuYing-Bin XiaoYong Wang Original Article 19 October 2023 Pages: 127 - 136
Changes in brown adipose tissue induced by resveratrol and its analogue pterostilbene in rats fed with a high-fat high-fructose diet Iker Gómez-GarcíaAlfredo Fernández-QuintelaJenifer Trepiana Original Article Open access 16 October 2023
Involvement of the vagus nerve and hepatic gene expression in serum adiponectin concentrations in mice Naoto HashimotoRyuji NagataMichihiro Fukushima Original Article 14 October 2023 Pages: 99 - 112
DERL2 (derlin 2) stabilizes BAG6 (BAG cochaperone 6) in chemotherapy resistance of cholangiocarcinoma Luzheng LiuJincai WuYong Wang Original Article Open access 10 October 2023 Pages: 81 - 97
The SGLT2 inhibitor empagliflozin attenuates atherosclerosis progression by inducing autophagy Hualin XuJie FuZheng Cao Original Article 04 October 2023 Pages: 27 - 39
Binge drinking leads to an oxidative and metabolic imbalance in skeletal muscle during adolescence in rats: endocrine repercussion Inés Romero-HerreraFátima NogalesMaría Luisa Ojeda Original Article Open access 07 September 2023 Pages: 799 - 810
Role of sonic hedgehog signaling pathway in the regulation of ion channels: focus on its association with cardio-cerebrovascular diseases Ming-Rui LiXiu-Ju LuoJun Peng Review 07 September 2023 Pages: 719 - 730
Gut microbial metabolites of dietary polyphenols and their potential role in human health and diseases Anushree GadeMaushmi S. Kumar Review 01 September 2023 Pages: 695 - 718
Comprehensive analysis of epigenetic and epitranscriptomic genes’ expression in human NAFLD Jose M. HerranzAmaya López-PascualMaite G Fernández-Barrena Original Article Open access 25 August 2023 Pages: 901 - 924