In Vivo and in Vitro Analysis of Skin Penetration Enhancement Based on a Two-Layer Diffusion Model with Polar and Nonpolar Routes in the Stratum Corneum Fumiyoshi YamashitaHiroto BandoMitsuru Hashida OriginalPaper Pages: 185 - 191
Evaluation of Retinoids as Therapeutic Agents in Dermatology Anita H. LewinMary E. BosF. Ivy Carroll OriginalPaper Pages: 192 - 200
Solubility Predictions for Solid Nitriles and Tertiary Amides Based on the Mobile Order Theory Paul RuelleUlrich W. Kesselring OriginalPaper Pages: 201 - 205
A Mixed Micellar Formulation Suitable for the Parenteral Administration of Taxol Hayat Alkan-OnyukselSuganthi RamakrishnanJohn M. Pezzuto OriginalPaper Pages: 206 - 212
Pharmacokinetics and Tissue Distribution of Recombinant Human Transforming Growth Factor Beta1 After Topical and Intravenous Administration in Male Rats Thomas F. ZioncheckSharon A. ChenJoyce Mordenti OriginalPaper Pages: 213 - 220
Solute Absorption from the Airways of the Isolated Rat Lung. IV. Mechanisms of Absorption of Fluorophore-Labeled Poly-α,β-[N(2-Hydroxyethyl)-DL-Aspartamide] Peter R. ByronZhuang SunFrantisek Rypacek OriginalPaper Pages: 221 - 225
Colonic Absorption of Insulin-like Growth Factor I in Vitro Elizabeth QuadrosNancy M. LandzertGregory Worosila OriginalPaper Pages: 226 - 230
Formulation and in Vitro–in Vivo Evaluation of Buccoadhesive Morphine Sulfate Tablets Şule AnlarYilmaz ÇapanAtillâ Hincal OriginalPaper Pages: 231 - 236
The Physicochemical Properties, Plasma Enzymatic Hydrolysis, and Nasal Absorption of Acyclovir and Its 2′-Ester Prodrugs Zezhi ShaoGee-Bae ParkAshim K. Mitra OriginalPaper Pages: 237 - 242
Bile Salt–Fatty Acid Mixed Micelles as Nasal Absorption Promoters. III. Effects on Nasal Transport and Enzymatic Degradation of Acyclovir Prodrugs Zezhi ShaoAshim K. Mitra OriginalPaper Pages: 243 - 250
Identification of the Pathway of lontophoretic Drug Delivery: Light and Ultrastructural Studies Using Mercuric Chloride in Pigs Nancy A. Monteiro-RiviereAlfred O. InmanJim E. Riviere OriginalPaper Pages: 251 - 256
Comparative Molecular Field Analysis Combined with Physicochemical Parameters for Prediction of Polydimethylsiloxane Membrane Flux in Isopropanol Rong LiuLloyd E. Matheson OriginalPaper Pages: 257 - 266
Intestinal Absorption of (–)-Carbovir in the Rat Inmaculada SoriaCheryl L. Zimmerman OriginalPaper Pages: 267 - 271
The Controlled Release of Prednisolone Using Alginate Gel Shinya SugawaraTeruko ImaiMasaki Otagiri OriginalPaper Pages: 272 - 277
Effect of Formulation Additives upon the Intranasal Bioavailability of a Peptide Drug: Tetracosactide (ACTH1−24) Patrick WüthrichMyriam MartenetPierre Buri OriginalPaper Pages: 278 - 282
Determination of Transport Rates for Arginine and Acetaminophen in Rabbit Intestinal Tissues in Vitro Peter W. SwaanGary J. MarksPhilip L. Smith OriginalPaper Pages: 283 - 287
Effect of Some Penetration Enhancers on Epithelial Membrane Lipid Domains: Evidence from Fluorescence Spectroscopy Studies T. Marjukka TurunenArto UrttiJ. Howard Rytting OriginalPaper Pages: 288 - 294
Effect of the H2-Receptor Antagonist Cimetidine, on the Pharmacokinetics and Pharmacodynamics of the H1-Receptor Antagonists Hydroxyzine and Cetirizine in Rabbits Xueyu ChenF. Estelle R. SimonsKeith J. Simons OriginalPaper Pages: 295 - 300
Improved Dose Linearity of Cyclosporine Pharmacokinetics from a Microemulsion Formulation Edgar A. MuellerJohn M. KovarikKlaus Kutz OriginalPaper Pages: 301 - 304
In Vivo and in Vitro Blood–Brain Barrier Transport of 3-Hydroxy-3-Methylglutaryl Coenzyme A (HMG-CoA) Reductase Inhibitors Akira SahekiTetsuya TerasakiAkira Tsuji OriginalPaper Pages: 305 - 311
Efflux of Zidovudine and 2′,3′-Dideoxyinosine Out of the Cerebrospinal Fluid When Administered Alone and in Combination to Macaca nemestrina Tove TuntlandRashid J. RavascoJashvant D. Unadkat OriginalPaper Pages: 312 - 317
Phenobarbital Removal Characteristics of Three Brands of Activated Charcoals: A System Analysis Approach Nishit B. ModiPeter Veng-PedersenDorothy D. Schottelius OriginalPaper Pages: 318 - 323
In Vitro and in Vivo Transport of Zidovudine (AZT) Across the Blood–Brain Barrier and the Effect of Transport Inhibitors Rosalinde MasereeuwUlrich JaehdeDouwe D. Breimer OriginalPaper Pages: 324 - 330
Fluorometric Study of the Molecular States of 2,5-Diphenyloxazole in Ground Mixtures with γ-Cyclodextrin Keiji YamamotoToshio OguchiYoshinobu Nakai OriginalPaper Pages: 331 - 336
Entrapment of Proteins in Poly(L-Lactide) Microspheres Using Reversed Micelle Solvent Evaporation Yoshiki HayashiSumie YoshiokaTadao Terao Note Pages: 337 - 340
Lack of Pharmacokinetic Interaction Between Cimetidine and Tirilazad Mesylate Joseph C. FleishakerLaura K. HulstGary R. Peters Note Pages: 341 - 344
Degradation of the Antiarthritic Prodrug, 3-Carboxy-5-methyl-N-[4-(trifluoromethoxy)phenyl]-4-isoxazolecarboxamide, in Aqueous Solution Michael BrandlJames A. Kennedy Note Pages: 345 - 348
Further Commentary: Physiological Parameters in Laboratory Animals and Humans Robert B. SothernScott A. Gruber Commentary Pages: 349 - 350