REFERENCES
V. H. L. Lee. Peptide and Protein Drug Delivery, Marcel Dekker, New York, 1992.
Y. Ogawa, M. Yamamoto, H. Okada, T. Yashiki, and T. Shimamoto. A new technique to efficiently entrap leuprolide acetate into microcapsules of polylactic acid or copoly(lactic/glycolic) acid. Chem. Pharm. Bull. 36:1095–1103 (1988).
Y. Tabata, S. Gutta, and R. Langer. Controlled delivery systems for proteins using polyanhydride microspheres. Pharm. Res. 10:487–496 (1993).
S. Cohen, T. Yoshioka, M. Lucarelli, L. H. Hwang, and R. Langer. Controlled delivery systems for proteins based on poly(lactic/glicolic acid) microspheres. Pharm. Res. 8:713–720 (1991).
H. Jeffery, S. S. Davis, and D. T. O'Hagan. The preparation and characterization of poly(lactide-co-glycolide) microspheres. II. The entrapment of a model protein using a (water-in oil)-in-water emulsion solvent evaporation technique. Pharm. Res. 10:362–368 (1993).
K. Martinek, A. V. Levashhov, N. Klyachko, Y. L. Khmelnitski, and I. V. Berezin. Micellar enzymology. Eur. J. Biochem. 155:453–468 (1986).
J. M. McCord and I. Fridovich. Superoxide Dismutase. J. Biol. Chem. 244:6049–6055 (1969).
Y. Tanaka, A. Kagamiishi, A. Kikuchi, and T. Horiuchi. Purification and properties of β-galactosidase from asperbillus oryzae. J. Biochem. 77:241–247 (1975).
N. Sunahara, S. Kuroka, K. Kaibe, Y. Ohkaru, S. Nishimura, K. Nakano, Y. Sohmura, and M. Iida. Simple enzyme immunoassay methods for recombinant human tumor necrosis factor and its antibodies using a bacterial cell wall carrier. J. Immunol. Methods 109:203–214 (1988).
S. Izumikawa, S. Yoshioka, Y. Aso, and Y. Takeda. Preparation of poly(l-lactide) microspheres of different crystalline morphology and effect of crystalline morphology on drug release rate. J. Control. Release 15:133–140 (1991).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Hayashi, Y., Yoshioka, S., Aso, Y. et al. Entrapment of Proteins in Poly(L-Lactide) Microspheres Using Reversed Micelle Solvent Evaporation. Pharm Res 11, 337–340 (1994). https://doi.org/10.1023/A:1018936314861
Issue Date:
DOI: https://doi.org/10.1023/A:1018936314861