1. Neuroinflammation in Alzheimer’s Disease: Current Progress in Molecular Signaling and Therapeutics

   • Sujata Thakur
   • Rishika Dhapola
   • Dibbanti HariKrishna Reddy

   Review 20 August 2022 Pages: 1 - 17

   

2. Structure Composition and Intracellular Transport of Clathrin-Mediated Intestinal Transmembrane Tight Junction Protein

   • Yi-Yang Pan
   • Ying Deng
   • Guang-Sheng Du

   Review 01 September 2022 Pages: 18 - 34

   

3. NLRP3 Inflammasome in Atherosclerosis: Putting Out the Fire of Inflammation

   • Bo-Zong Shao
   • Hai-Yan Xu
   • Guan-Ren Zhao

   Review 11 August 2022 Pages: 35 - 46

   

4. The Role of Macrophages and Alveolar Epithelial Cells in the Development of ARDS

   • Huan Tao
   • Younian Xu
   • Shihai Zhang

   Review 01 September 2022 Pages: 47 - 55

   

5. Role of NLRP3 Inflammasome and Its Inhibitors as Emerging Therapeutic Drug Candidate for Alzheimer’s Disease: a Review of Mechanism of Activation, Regulation, and Inhibition

   • Barkha Sharma
   • Garvit Satija
   • Mohammad Ahmed Khan

   Review 25 August 2022 Pages: 56 - 87

   

6. Role of T Cells in the Pathogenesis of Rheumatoid Arthritis: Focus on Immunometabolism Dysfunctions

   • Maryam Masoumi
   • Samira Alesaeidi
   • Jafar Karami

   Review 10 October 2022 Pages: 88 - 102

   

7. Investigation of TLR4 Antagonists for Prevention of Intestinal Inflammation

   • Janine S. Y. Tam
   • Janet K. Coller
   • Joanne M. Bowen

   Original Article Open access 22 July 2022 Pages: 103 - 114

   

8. PCSK9 Promotes Endothelial Dysfunction During Sepsis Via the TLR4/MyD88/NF-κB and NLRP3 Pathways

   • Longxiang Huang
   • Yuanjing Li
   • Yong Xia

   Original Article 05 August 2022 Pages: 115 - 128

   

9. Hyperglycemia Aggravates Blood–Brain Barrier Disruption Following Diffuse Axonal Injury by Increasing the Levels of Inflammatory Mediators through the PPARγ/Caveolin-1/TLR4 Pathway

   • Xing Wei
   • Yaqing Zhou
   • Yonglin Zhao

   Original Article 20 July 2022 Pages: 129 - 145

   

10. The Pathogenic Role of Oxidative Stress, Cytokine Expression, and Impaired Hematological Indices in Diabetic Cardiovascular Diseases

    • Howaida Saad
    • Hanan A. Soliman
    • Mohamed Y. Zaky

    Original Article Open access 23 August 2022 Pages: 146 - 160

    

11. Circ_0088194 Regulates Proliferation, Migration, Apoptosis, and Inflammation by miR-30a-3p/ADAM10 Axis in Rheumatoid Arthritis Fibroblastic Synovial Cells

    • Lei Feng
    • Wenseng Jing
    • Bo Wang

    Original Article 02 August 2022 Pages: 161 - 174

    

12. Morin Augmented Myocardial eNOS/cGMP/PKG Signaling Pathway and Abated Oxidative and Inflammo-apoptotic Responses in Diethyl Phthalate and Bisphenol-S Co-Exposed Male Albino Rats

    • Adewale Segun James
    • Ofem Effiom Eteng
    • Regina Ngozi Ugbaja

    Original Article 28 July 2022 Pages: 175 - 189

    

13. Anti-inflammatory Effect of a Limonin Derivative In Vivo and Its Mechanisms in RAW264.7 Cells

    • Ning Wang
    • Xiao Chen
    • Guoqing Gong

    Original Article 20 August 2022 Pages: 190 - 201

    

14. Macrophage-Derived TGF-β and VEGF Promote the Progression of Trauma-Induced Heterotopic Ossification

    • Bing Tu
    • Juehong Li
    • Cunyi Fan

    Original Article 20 August 2022 Pages: 202 - 216

    

15. Convergence of Fructose-Induced NLRP3 Activation with Oxidative Stress and ER Stress Leading to Hepatic Steatosis

    • Sushmita Singh
    • Aditya Sharma
    • Akhilesh K. Tamrakar

    Original Article 09 August 2022 Pages: 217 - 233

    

16. Silence of S1PR4 Represses the Activation of Fibroblast-like Synoviocytes by Regulating IL-17/STAT3 Signaling Pathway

    • Pengyu Zhang
    • Qiang Zhang
    • Zhenxia Shao

    Original Article 06 September 2022 Pages: 234 - 243

    

17. Multiplex Assessment of Serum Chemokines CCL2, CCL5, CXCL1, CXCL10, and CXCL13 Following Traumatic Brain Injury

    • Yuwen Chen
    • Ying Wang
    • Su Liu

    Original Article 15 August 2022 Pages: 244 - 255

    

18. Substance P Exacerbates the Inflammatory and Pro-osteoclastogenic Responses of Murine Osteoclasts and Osteoblasts to Staphylococcus aureus

    • M. Brittany Johnson
    • Samantha R. Suptela
    • Ian Marriott

    Original Article 30 August 2022 Pages: 256 - 269

    

19. Hypoxia-Inducible Factor-1α Protects Against Intervertebral Disc Degeneration Through Antagonizing Mitochondrial Oxidative Stress

    • Wen Yang
    • Chunwang Jia
    • Lei Zhang

    Original Article Open access 06 September 2022 Pages: 270 - 284

    

20. Plasma IL-36α and IL-36γ as Potential Biomarkers in Interstitial Lung Disease Associated with Rheumatoid Arthritis: a Pilot Study in the Chinese Population

    • Weishuai Zheng
    • Xingxing Hu
    • Zhenshun Cheng

    Original Article 31 August 2022 Pages: 285 - 296

    

21. SARS-CoV-2 Variants Show a Gradual Declining Pathogenicity and Pro-Inflammatory Cytokine Stimulation, an Increasing Antigenic and Anti-Inflammatory Cytokine Induction, and Rising Structural Protein Instability: A Minimal Number Genome-Based Approach

    • Debmalya Barh
    • Sandeep Tiwari
    • Murtaza M. Tambuwala

    Original Article 10 October 2022 Pages: 297 - 312

    

22. Diagnostic and Prognostic Value of Deregulated Circulating Long Non-coding RNA TUG1 in Elderly Patients with Severe Pneumonia

    • Kai Gong
    • Jiao Xu
    • Jianlei Tang

    Original Article 15 September 2022 Pages: 313 - 321

    

23. The Influenza-Induced Pulmonary Inflammatory Exudate in Susceptible Tpl2-Deficient Mice Is Dictated by Type I IFN Signaling

    • Krishna Latha
    • Yesha Patel
    • Wendy T. Watford

    Original Article 13 October 2022 Pages: 322 - 341

    

24. Mechanistic Approach for Protective Effect of ARA290, a Specific Ligand for the Erythropoietin/CD131 Heteroreceptor, against Cisplatin-Induced Nephrotoxicity, the Involvement of Apoptosis and Inflammation Pathways

    • Nasrin Ghassemi-Barghi
    • Zeynab Ehsanfar
    • Zahra Bayrami

    Original Article 10 September 2022 Pages: 342 - 358

    

25. Transmembrane TNF-α as a Novel Biomarker for the Diagnosis of Cytokine Storms in a Mouse Model of Multiple Organ Failure

    • Peng Yang
    • Yimin Zeng
    • Ruping Zhang

    Original Article Open access 14 September 2022 Pages: 359 - 369

    

26. MicroRNA-19a Inhibition Directly and Indirectly Ameliorates Th2 Airway Inflammation in Asthma by Targeting RUNX3

    • Shaojun He
    • Jingrun Zhou
    • Jiong Yang

    Original Article 16 September 2022 Pages: 370 - 387

    

27. Omega-3 Effects on Ligature-Induced Periodontitis in Rats with Fructose-Induced Metabolic Syndrome

    • Maysa O. A. Oliveira
    • Álvaro R. Leonço
    • Maria M. Campos

    Original Article 29 September 2022 Pages: 388 - 403

    

28. Knockout of ICAT in Adipose Tissue Alleviates Fibro-inflammation in Obese Mice

    • Zhuan Song
    • Ning Liu
    • Zhenlong Wu

    Original Article 01 October 2022 Pages: 404 - 417

    

29. Pyruvate Dehydrogenase Kinase 2 Accelerates Endotoxin Shock by Promoting Mitogen-Activated Protein Kinase Activation

    • Chunxia Li
    • Jun Dai
    • Huabao Xiong

    Original Article 29 September 2022 Pages: 418 - 431

    

30. Targeting Oxidative Stress Markers, Xanthine Oxidase, TNFRSF11A and Cathepsin L in Curcumin-Treated Collagen-Induced Arthritis: A Physiological and COSMO-RS Study

    • Seghira Bisset
    • Widad Sobhi
    • Yacine Benguerba

    Original Article 13 October 2022 Pages: 432 - 452

    

31. Dimethyl Fumarate Attenuates Di-(2-Ethylhexyl) Phthalate-Induced Nephrotoxicity Through the Nrf2/HO-1 and NF-κB Signaling Pathways

    • Sorour Ashari
    • Navid Naghsh
    • Abouzar Bagheri

    Original Article 05 October 2022 Pages: 453 - 467

    

32. Decreased Th1 Cells and Increased Th2 Cells in Peripheral Blood Are Associated with Idiopathic Inflammatory Myopathies Patients with Interstitial Lung Disease

    • Lu Cheng
    • Yanhong Li
    • Yi Liu

    Original Article 20 October 2022 Pages: 468 - 479

    

33. Interleukin-33/ST2 Axis as Potential Biomarker and Therapeutic Target in Kawasaki Disease

    • Seigo Okada
    • Hiroki Yasudo
    • Shunji Hasegawa

    Original Article 08 October 2022 Pages: 480 - 490