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Prospecting potential of endophytes for modulation of biosynthesis of therapeutic bioactive secondary metabolites and plant growth promotion of medicinal and aromatic plants

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Abstract

Medicinal and aromatic plants possess pharmacological properties (antidiabetes, anticancer, antihypertension, anticardiovascular, antileprosy, etc.) because of their potential to synthesize a wide range of therapeutic bioactive secondary metabolites. The concentration of bioactive secondry metabolites depends on plant species, local environment, soil type and internal microbiome. The internal microbiome of medicinal plants plays the crucial role in the production of bioactive secondary metabolites, namely alkaloids, steroids, terpenoids, peptides, polyketones, flavonoids, quinols and phenols. In this review, the host specific secondry metabolites produced by endophytes, their therapeutic properties and host-endophytes interaction in relation to production of bioactive secondry metaboloites and the role of endophytes in enhancing the production of bioactive secondry metabolites is discussed. How biological nitrogen fixation, phosphorus solubilization, micronutrient uptake, phytohormone production, disease suppression, etc. can play a vital role in enhacing the plant growth and development.The role of endophytes in enhancing the plant growth and content of bioactive secondary metabolites in medicinal and aromatic plants in a sustainable mode is highlighted.

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Acknowledgements

The authors are thankful to ICAR-CAZRI, Jodhpur , Rajasthan for their valuable support during this study.

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Authors and Affiliations

  1. ICAR-Central Arid Zone Research Institute, Jodhpur, Rajasthan, 342003, India

    Devendra Singh & S. K. Singh

  2. ICAR-National Bureau of Agriculturally Important Microorganisms, Kushmaur, Mau Nath Bhanjan, Uttar Pradesh, 275103, India

    Shobit Thapa

  3. ICAR-Directorate of Weed Research (DWR), Maharajpur, Jabalpur, Madhya Pradesh, 482004, India

    Himanshu Mahawar

  4. ICAR- Central Potato Research Institute, Shimla, Himachal Pradesh, 171001, India

    Dharmendra Kumar

  5. Agricultural Research Station, Agriculture University, Jodhpur, Rajasthan, 342304, India

    Neelam Geat

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  1. Devendra Singh
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DS and NG prepared the initial draft of the review. HM, ST, DK helped with drafting and editing. SKS helped in final review & editing. All authors have read and agreed to the final version of the manuscript.

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Singh, D., Thapa, S., Mahawar, H. et al. Prospecting potential of endophytes for modulation of biosynthesis of therapeutic bioactive secondary metabolites and plant growth promotion of medicinal and aromatic plants. Antonie van Leeuwenhoek 115, 699–730 (2022). https://doi.org/10.1007/s10482-022-01736-6

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