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Mobilization of Chromosomes and Nonconjugative Plasmids by Cointegrative Mechanisms

  • Chapter
Bacterial Conjugation

Abstract

Conjugative plasmids in bacteria bring about the transfer of DNA by cell contact between a donor and a recipient (250). Naturally occurring conjugative plasmids transfer themselves. Furthermore, in many cases they can also transfer (mobilize) chromosomal DNA or nonconjugative plasmids. Thus, mobilization, as we define it, is the process by which a conjugative plasmid accomplishes the transfer of DNA that is not self-transmissible.

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References

  1. Allibert, P., Willison, J. C., and Vignais, P. M., 1987, Complementation of nitrogen-regulatory (ntr-like) mutations in Rhodobacter capsulatus by an Escherichia coli gene: Cloning and sequencing of the gene and characterization of the gene product, J. Bacteriol. 169: 260–271.

    PubMed  CAS  Google Scholar 

  2. Al-Taho, N. M., and Warner, P. J., 1987, Restoration of phenotype in Escherichia coli auxotrophs by pULB113-mediated mobilisation from methylotrophic bacteria, FEMS Microbiol. Lett. 43: 235–239.

    Article  Google Scholar 

  3. Anderson, P., 1987, Twenty years of illegitimate recombination, Genetics 115: 581–584.

    PubMed  CAS  Google Scholar 

  4. Arthur, A., and Sherratt, D., 1979, Dissection of the transposition process: A transposon-encoded site-specific recombination system, Mol. Gen. Genet. 175: 267–274.

    Article  PubMed  CAS  Google Scholar 

  5. Arthur, A., Nimmo, E., Hettle, S., and Sherratt, D., 1984, Transposition and transposition immunity of transposon Tn3 derivatives having different ends, EMBO J. 3: 1723–1729.

    PubMed  CAS  Google Scholar 

  6. Avila, P., de la Cruz, F., Ward, E., and Grinsted, J., 1984, Plasmids containing one inverted repeat of Tn21 can fuse with other plasmids in the presence of Tn21 transposase, Mol. Gen. Genet. 195: 288–293.

    Article  PubMed  CAS  Google Scholar 

  7. Bagdasarian, M., Hryniewicz, M., Zdzienicka, M., and Bagdasarian, M., 1975, Integrative suppression of a dna mutation in Salmonella typhimurium, Mol. Gen. Genet. 139: 213–231.

    PubMed  CAS  Google Scholar 

  8. Bainton, R., Gamas, P., and Craig, N. L., 1991, Tn7 transposition in vitro proceeds through an excised transposon intermediate generated by staggered breaks in DNA, Cell 65: 805–816.

    Article  PubMed  CAS  Google Scholar 

  9. BSnfalvi, Z., Randhawa, G. S., Kondorosi, E., Kiss, A., and Kondorosi, A., 1983, Construction and characterization of R-prime plasmids carrying symbiotic genes of R. meliloti, Mol. Gen. Genet. 189: 129–135.

    Article  Google Scholar 

  10. Barlett, M. M., Erickson, J. M., and Meyer, R. J., 1990, Recombination between directly repeated origins of conjugative transfer cloned in M13 bacteriophage DNA models ligation of the transferred plasmid strand, Nucleic Acids Res. 18: 3579–3586.

    Article  PubMed  CAS  Google Scholar 

  11. Barrett, J. T., Rhodes, C. S., Ferber, D. M., Jenkins, B., Kuhl, S. A., and Ely, B., 1982, Construction of a genetic map for Caulobacter crescentus, J. Bacteriol. 149: 889–896.

    PubMed  CAS  Google Scholar 

  12. Barth, P T., 1979, Plasmid RP4, with Escherichia coli DNA inserted in vitro, mediates chromosomal transfer, Plasmid 2: 130–136.

    Article  PubMed  CAS  Google Scholar 

  13. Bashkirov, V. I., Khasanov, F. K., and Prozorov, A. A., 1987, Illegitimate recombination in Bacillus subtilis: Nucleotide sequences at recombinant DNA junctions, Mol. Gen. Genet. 210: 578–580.

    Article  PubMed  CAS  Google Scholar 

  14. Beck, Y., Coetzee, W. F., and Coetzee, J. N., 1982, In vitro-constructed RP4-prime plasmids mediate orientated mobilization of the Proteus morganii chromosome, J. Gen. Microbiol. 128: 1163–1169.

    CAS  Google Scholar 

  15. Beeching, J. R., Weightman, A. J., and Slater, J. H., 1983, The formation of an R-prime carrying the fraction I dehalogenase gene from Pseudomonas putida PP3 using the IncP plasmic R68.44, J. Gen. Microbiol. 129: 2071–2078.

    CAS  Google Scholar 

  16. Benjamin, H. W., and Kleckner, N., 1992, Excision of Tn10 from the donor site during transposition occurs by flush double strand cleavages at the transposon termini, Proc. Natl. Acad. Sci. USA 89: 46484652.

    Google Scholar 

  17. Bennett, R M., de la Cruz, F., and Grinsted, J., 1983, Cointegrates are not obligatory intermediates in transposition of Tn3 and Tn21, Nature 305: 743–744.

    Article  CAS  Google Scholar 

  18. Bennett, P. M., Heritage, J., Comanducci, A., and Dodd, H. M., 1986, Evolution of R plasmids by replicon fusion, J. Antimicrob. Chemother. 18 (Suppl. C): 103–111.

    Article  PubMed  CAS  Google Scholar 

  19. Bennett, P. M., Grinsted, J., and Foster, T. J., 1990, Detection and use of transposons, in: Methods in Microbiology, Vol. 21 ( J. Grinsted and P. M. Bennett, eds.), Academic Press, London, pp. 205–231.

    Google Scholar 

  20. Benson, S., and Shapiro, J., 1978, TOL is a broad-host-range plasmid, J. Bacteriol. 135: 278–280.

    PubMed  CAS  Google Scholar 

  21. Berg, C. M., and Curtiss,111, R., 1967, Transposition derivatives of an Hfr strain of Escherichia coli K-12, Genetics 56: 503–525.

    PubMed  CAS  Google Scholar 

  22. Berg, C. M., Berg, D. E., and Groisman, E. A., 1989, Transposable elements and the genetic engineering of bacteria, in: Mobile DNA ( D. E. Berg and M. M. Howe, eds.), American Society for Microbiology, Washington, D. C., pp. 879–925.

    Google Scholar 

  23. Berg, D. E., 1977, Insertion and excision of the transposable kanamycin resistance determinant Tn5, in: DNA Insertion Elements, Plasmids, and Episomes ( A. I. Bukhari, J. A. Shapiro, and S. L. Adhya, eds.), Cold Spring Harbor Laboratory, Cold Spring Harbor, N. Y., pp. 205–212.

    Google Scholar 

  24. Berg, D. E., 1989, Transposon Tn5, in: Mobile DNA ( D. E. Berg and M. M. Howe, eds.), American Society for Microbiology, Washington, D.C., pp. 185–210.

    Google Scholar 

  25. Beringer, J. E., and Hopwood, D. A., 1976, Chromosomal recombination and mapping in Rhizobium leguminosarum, Nature 264: 291–293.

    Article  PubMed  CAS  Google Scholar 

  26. Beringer J. E., Hoggan, S. A., and Johnston, A. W. B., 1978, Linkage mapping in Rhizobium leguminosarum by means of R plasmid-mediated recombination, J. Gen. Microbiol. 104: 201–207.

    Google Scholar 

  27. Beringer, J. E., Johnston, A. W. B., and Kondorosi, A., 1987, Rhizobium meliloti and Rhizobium leguminosarum, in: Genetic Maps, Vol. 4 (S. J. O’Brien, ed.), Cold Spring Harbor Laboratory, Cold Spring Harbor, N.Y., pp. 245–251.

    Google Scholar 

  28. Bhattacharjee, M. K., and Meyer, R. J., 1991, A segment of a plasmid gene required for conjugal transfer encodes a site-specific, single-strand DNA endonuclease and ligase, Nucleic Acids Res. 19: 1129–1137.

    Article  PubMed  CAS  Google Scholar 

  29. Biel, S. W, and Berg, D. E., 1984, Mechanism of IS1 transposition in E. coli: Choice between simple insertion and cointegration, Genetics 108: 319–330.

    PubMed  CAS  Google Scholar 

  30. Birkenbihl, R. P., and Vielmetter, W., 1989, Complete maps of IS1, IS2, IS3, IS4, ISS, IS30 and IS150 locations in Escherichia coli K12, Mol. Gen. Genet. 220: 147–153.

    Article  PubMed  CAS  Google Scholar 

  31. Bissonette, L., and Roy, P H., 1992, Characterization of In0 of Pseudomonas aeruginosa plasmid pVS1, an ancestor of integrons of multiresistance plasmids and transposons of gram-negative bacteria, J. Bacteriol. 175: 1248–1257.

    Google Scholar 

  32. Bittle, C., and Konopka, A., 1990, IncP-mediated transfer of loci involved with gas vesicle production in Ancylobacter aquaticus, J. Gen. Microbiol. 136: 1259–1263.

    CAS  Google Scholar 

  33. Blanco, G., Gutierrez, J. C., Ramos, E, and Tortolero, M., 1991, Isolation and characterization of R-primes of Azotobacter vinelandii, FEMS Microbiol. Lett. 80: 213–216.

    Article  CAS  Google Scholar 

  34. Boccard, F., Smokvina, T., Pernodet, J.-L., Friedmann, A., and Guérineau, M., 1989, The integrated conjugative plasmid pSAM2 of Streptomyces ambofaciens is related to temperate bacteriophages, EMBO J. 8: 973–980.

    PubMed  CAS  Google Scholar 

  35. Bowen, A. R. S. G., and Pemberton, J. M., 1985, Mercury resistance transposon Tn813 mediates chromosome transfer in Rhodopseudomonas sphaeroides and intergeneric transfer of pBR322, in: Plasmids in Bacteria ( D. R. Helinski, S. N. Cohen, D. B. Clewell, D. A. Jackson, and A. Hollaender, eds.), Plenum Press, New York, pp. 105–115.

    Chapter  Google Scholar 

  36. Boyd, A. C., Archer, J. A. K., and Sherratt, D. J., 1989, Characterization of the ColE1 mobilization region and its protein products, Mol. Gen. Genet. 217: 488–498.

    Article  PubMed  CAS  Google Scholar 

  37. Brandt, R., Günther, E., and Herrmann, H., 1984, Mapping of cysteine genes on the chromosome of Pseudomonas aeruginosa PAO, Mol. Gen. Genet. 197: 292–296.

    Article  PubMed  CAS  Google Scholar 

  38. Bray, R., Strom, D., Barton, J., Dean, H. F., and Morgan, A. F, 1987, Isolation and characterization of Pseudomonas putida R-prime plasmids, J. Gen. Microbiol. 133: 683–690.

    PubMed  CAS  Google Scholar 

  39. Bresler, S. E., Krivonogov, S. V, and Lanzov, V. A., 1979, Genetic determination of the donor properties in Escherichia coli K-12, Mol. Gen. Genet. 177: 177–184.

    Article  PubMed  CAS  Google Scholar 

  40. Breton, A. M., Jaoua, S., and Guespin-Michel, J., 1985, Transfer of plasmid RP4 to Myxococcus xanthus and evidence for its integration into the chromosome, J. Bacteriol. 161: 523–528.

    PubMed  CAS  Google Scholar 

  41. Broome-Smith, J., 1980, RecA independent, site-specific recombination between ColE1 or ColK and a miniplasmid they complement for mobilization and relaxation: Implications for the mechanism of DNA transfer during mobilization, Plasmid 4: 51–63.

    Article  PubMed  CAS  Google Scholar 

  42. Brown, P 0., 1990, Integration of retroviral DNA, in: Retroviruses—Strategies of Replication ( R. Swanstrom and P K. Vogt, eds.), Springer Verlag, Berlin, pp. 19–48.

    Chapter  Google Scholar 

  43. Bryan, J., Saeed, N., Fox, D., and Sastry, G. R. K., 1982, R68.45 mediated chromosomal gene transfer in Agrobacterium tumefaciens, Arch. Microbiol. 131: 271–277.

    Article  PubMed  CAS  Google Scholar 

  44. Bushman, F D., Fujiwara, T., and Craigie, R., 1990, Retroviral DNA integration directed by HIV integration protein in vitro, Science 249: 1555–1558.

    Article  PubMed  CAS  Google Scholar 

  45. Bushman, F D., and Craigie, R., 1991, Activities of human immunodeficiency virus (HIV) integration protein in vitro: Specific cleavage and integration of HIV DNA, Proc. Natl. Acad. Sci. USA 88: 1339–1343.

    Article  PubMed  CAS  Google Scholar 

  46. Campbell, A., 1962, Episomes, Adv. Genet. 11: 101–145.

    Article  Google Scholar 

  47. Carter, J. R., and Porter, R. D., 1991, traY and tral are required for oriT-dependent enhanced recombination between lac-containing plasmids and Xplac5, J. Bacteriol. 173: 1027–1034.

    Google Scholar 

  48. Chakrabarty, A. M., and Gunsalus, I. C., 1979, Chromosomal mobilization from a recA mutant of Pseudomonas putida, Mol. Gen. Genet. 176: 151–154.

    Article  PubMed  CAS  Google Scholar 

  49. Chandler, M., Silver, L., Roth, Y., and Caro, L., 1976, Chromosome replication in an Hfr strain of Escherichia coli, J. Mol. Biol. 104: 517–523.

    Article  PubMed  CAS  Google Scholar 

  50. Chandler, M., Silver, L., and Caro, L., 1977, Suppression of an Escherichia coli dnaA mutation by the integrated R factor R100.1: Origin of chromosome replication during exponential growth, J. Bacteriol. 131: 421–430.

    PubMed  CAS  Google Scholar 

  51. Chandler, M., Roulet, E., Silver, L., Boy de la Tour, E., and Caro, L., 1979, Tn10 mediated integration of the plasmid R100.1 into the bacterial chromosome: Inverse transposition, Mol. Gen. Genet. 173: 23–30.

    Google Scholar 

  52. Chandler, P. M., and Krishnapillai, V., 1974, Isolation and properties of recombination-deficient mutants of Pseudomonas aeruginosa, Mutation Res. 23: 15–23.

    Article  PubMed  CAS  Google Scholar 

  53. Chafer, K. F., Henderson, D. J., Bibb, M. J., and Hopwood, D. A., 1988, Genome flux in Streptomyces coelicolor and other streptomycetes and its possible relevance to the evolution of mobile antibiotic resistance determinants, in: Transposition ( A. J. Kingsman, K. F. Chater, and S. M. Kingsman, eds.), Cambridge University Press, Cambridge, England, pp. 7–42.

    Google Scholar 

  54. Chatterjee, A. K., 1980, Acceptance by Erwinia spp. of R plasmid R68.45 and its ability to mobilize the chromosome of Erwinia chrysanthemi, J. Bacteriol. 142: 111–119.

    PubMed  CAS  Google Scholar 

  55. Chatterjee, A. K., and Starr, M. P., 1973, Gene transmission among strains of Erwinia amylovora, J. Bacteriol. 116: 1100–1106.

    PubMed  CAS  Google Scholar 

  56. Chatterjee, A. K., and Starr, M. R, 1977, Donor strains of the soft-rot bacterium Erwinia chrysanthemi and conjugational transfer of the pectolytic capacity, J. Bacteriol. 132: 862–869.

    PubMed  CAS  Google Scholar 

  57. Chatterjee, A. K., and Starr, M. P., 1980, Genetics of Erwinia species, Annu. Rev. Microbiol. 34: 645–676.

    Article  PubMed  CAS  Google Scholar 

  58. Chatterjee, A. K., Ross, L. M., McEvoy, J. L., and Thurn, K. K., 1985, pULB113, an RP4::mini-Mu plasmid, mediates chromosomal mobilization and R-prime formation in Erwinia amylovora, Erwinia chrysanthemi, and subspecies of Erwinia carotovora, Appl. Environ. Microbiol. 50: 1–9.

    Google Scholar 

  59. Chilton, M-D., Farrand, S. K., Levin, R., and Nester, E. W, 1976, RP4 promotion of transfer of a large Agrobacterium plasmid which confers virulence, Genetics 83: 609–618.

    PubMed  CAS  Google Scholar 

  60. Chumley, F G., Menzel, R., and Roth, J. R., 1979, Hfr formation directed by Tn10, Genetics 91: 639–655.

    PubMed  CAS  Google Scholar 

  61. Clark, A. J., and Warren, G. J., 1979, Conjugal transmission of plasmids, Anna. Rev. Genet. 13: 99–125.

    Article  CAS  Google Scholar 

  62. Clewell, D. B., Tomich, P. K., Gawron-Burke, M. C., Franke, A. E., Yagi, Y., and An, F. Y.,1982, Mapping of Streptococcus faecalis plasmids pAD1 and pAD2 and studies relating to transposition of Tn917, J. Bacteriol. 152: 1220–1230.

    Google Scholar 

  63. Clowes, R. C., and Moody, E. E. M., 1966, Chromosomal transfer from “recombination-deficient” strains of Escherichia coli, Genetics 53: 717–726.

    PubMed  CAS  Google Scholar 

  64. Coetzee, J. N., 1978, Mobilization of the Proteus mirabilis chromosome by R plasmid R772, J. Gen. Microbiol. 108: 103–109.

    PubMed  CAS  Google Scholar 

  65. Coetzee, J. N., 1979, Patterns of mobilization of the Proteus mirabilis chromosome by R plasmids, J. Gen. Microbiol. 111: 243–251.

    PubMed  CAS  Google Scholar 

  66. Coetzee, J. N., van Dijken, M. C., and Coetzee, W. F., 1987, Proteus mirabilis, in: Genetic Maps, Vol. 4 (S. J. O’Brien, ed), Cold Spring Harbor Laboratory, Cold Spring Harbor, N. Y., pp. 224–229.

    Google Scholar 

  67. Cohen, A., Silberstein, Z., Broido, S., and Laban, A., 1985, General genetic recombination of bacterial plasmids, in: Plasmids in Bacteria ( D. R. Helinski, S. N. Cohen, D. B. Clewell, D. A. Jackson, and A. Hollaender, eds.), Plenum Press, New York, pp. 505–519.

    Chapter  Google Scholar 

  68. Colbeau, A., Magnin, J.-P., Cauvin, B., Champion, T, and Vignais, P. M., 1990, Genetic and physical mapping of an hydrogenase gene cluster from Rhodobacter capsulatus, Mol. Gen. Genet. 220: 393–399.

    Article  CAS  Google Scholar 

  69. Collis, C. M., and Hall, R. M., 1992, Gene cassette from the insert region of integrons are excised as covalently closed circles, Mol. Microbiol. 6: 2875–2885.

    Article  PubMed  CAS  Google Scholar 

  70. Craig, N. L., 1988, The mechanism of conservative site-specific recombination, Annu. Rev. Genet. 22: 77–105.

    Article  PubMed  CAS  Google Scholar 

  71. Craig, N. L., 1991, Tn7: A target site-specific transposon, Mol. Microbiol. 5: 2569–2573.

    Article  PubMed  CAS  Google Scholar 

  72. Cullum, J., and Broda, P., 1979, Chromosome transfer and Hfr formation by F in rec+ and recA strains of Escherichia coli K12, Plasmid 2: 358–365.

    Article  PubMed  CAS  Google Scholar 

  73. Currier, T. C., and Morgan, M. K., 1982, Direct DNA repeat in plasmid R68.45 is associated with deletion formation and concomitant loss of chromosome mobilization ability, J. Bacteriol. 150: 251–259.

    PubMed  CAS  Google Scholar 

  74. Curtiss, III, R., and Stallions, D. R., 1969, Probability of F integration and frequency of stable Hfr donors in F+ populations of Escherichia coli K-12, Genetics 63: 27–38.

    Google Scholar 

  75. Cuzin, F., and Jacob, E, 1967, Mutations de l’épisome F d’Escherichia coli K12. 2. Mutants à réplication thermosensible, Ann. Inst. Pasteur 112: 397–418.

    CAS  Google Scholar 

  76. Dalrymple, B., 1987, Novel rearrangements of IS30 carrying plasmids leading to the reactivation of gene expression, Mol. Gen. Genet. 207: 413–420.

    Article  PubMed  CAS  Google Scholar 

  77. Danilevich, V. N., and Kostyuchenko, D. A., 1986, Immunity to repeated insertion of IS21 sequence, Mol. Biol. 19: 1016–1022 (English translation).

    Google Scholar 

  78. Danilevich, V. N., Kostyuchenko, D. A., and Negrii, N. V, 1986, Interaction (incorporation and excision) of the plasmid pRP19.6, a derivative of RP1 containing a duplicated sequence IS21, with the chromosome of Escherichia coli K12, Mol. Biol. 19: 858–867 (English translation).

    Google Scholar 

  79. Datta, N., and Barth, P T., 1976, Hfr Formation by I pilus-determining plasmids in Escherichia coli K-12, J. Bacteriol. 125: 811–817.

    PubMed  CAS  Google Scholar 

  80. Davidson, N., Deonier, R. C., Hu, S., and Ohtsubo, E., 1975, Electron microscope heteroduplex studies of sequence relations among plasmids of Escherichia coli. X. Deoxyribonucleic acid sequence organization of F and F-primes, and the sequences involved in Hfr formation, in: Microbiology-1974 ( D. Schlessinger, ed.), American Society for Microbiology, Washington, D. C., pp. 56–65.

    Google Scholar 

  81. De Graaff, J., Kreuning, P. C., and Stouthamer, A. H., 1974, Isolation and characterization of Hfr males in Citrobacter freundii, Antonie van Leeuwenhoek J. Microbiol. 40: 161–170.

    Article  PubMed  Google Scholar 

  82. DeVries, J. K., and Maas, W K., 1971, Chromosomal integration of F’ factors in recombination-deficient Hfr strains of Escherichia coli, J. Bacteriol. 106: 150–156.

    PubMed  CAS  Google Scholar 

  83. Dean, H. F., and Morgan, A. F., 1983, Integration of R91–5::Tn501 into the Pseudomonas putida PPN chromosome and genetic circularity of the chromosomal map, J. Bacteriol. 153: 485–497.

    PubMed  CAS  Google Scholar 

  84. Deonier, R. C., and Davidson, N., 1976, The sequence organization of the integrated F plasmid in two Hfr strains of Escherichia coli, J. Mol. Biol. 107: 207–222.

    Article  PubMed  CAS  Google Scholar 

  85. Deonier, R. C., and Hadley, R. G., 1980, IS2–IS2 and IS3–IS3 relative recombination frequencies in F integration, Plasmid 3: 48–64.

    Article  PubMed  CAS  Google Scholar 

  86. Deonier, R. C., and Mirels, L., 1977, Excision of F plasmid sequences by recombination at directly repeated insertion sequence 2 elements: Involvement of recA, Proc. Natl. Acad. Sci. USA 74: 3965–3969.

    Article  PubMed  CAS  Google Scholar 

  87. Depicker, A., De Block, M., Inzé, D., Van Montagu, M., and Schell, J., 1980, IS-like element IS8 in RP4 plasmid and its involvement in cointegration, Gene 10: 329–338.

    Article  PubMed  CAS  Google Scholar 

  88. Dessaux, Y., Petit, A., Ellis, J. G., Legrain, C., Demarez, M., Wiame, J.-M., Popoff, M., and Tempé, J., 1989, Ti plasmid-controlled chromosome transfer in Agrobacterium tumefaciens, J. Bacteriol. 171: 63636366.

    Google Scholar 

  89. Dixon, D. A., and Kowalczykowski, S. C., 1991, Homologous pairing in vitro stimulated by the recombinant hotspot, Chi, Cell 66: 361–371.

    Article  PubMed  CAS  Google Scholar 

  90. Dixon, R., and Kinghorn, J. R., 1990, Separation of large DNA molecules by pulsed-field gel electrophoresis, Soc. Gen. Microbiol. Q. 17: 86–88.

    Google Scholar 

  91. Dixon, R., Cannon, E C., and Postgate, J. R., 1975, Properties of the R-factor R144drd3 in Klebsiella pneumoniae strain M5a1, Genet. Res. 28: 327–338.

    Article  Google Scholar 

  92. Dreyfus, L. A., and Iglewski, B. H., 1985, Conjugation-mediated genetic exchange in Legionella pneumophila, J. Bacteriol. 161: 80–84.

    PubMed  CAS  Google Scholar 

  93. Ehrlich, S. D., 1989, Illegitimate recombination in bacteria, in: Mobile DNA ( D. E. Berg and M. M. Howe, eds.), American Society for Microbiology, Washington, D. C., pp. 799–832.

    Google Scholar 

  94. Engelman, A., Mizuuchi, K., and Craigie, R., 1991, HIV-1 DNA integration: Mechanism of viral DNA cleavage and DNA strand transfer, Cell 67: 1211–1221.

    Article  PubMed  CAS  Google Scholar 

  95. Espin, G., Alvarez-Morales, A., and Merrick, M., 1981, Complementation analysis of glnA-linked mutations which affect nitrogen fixation in Klebsiella pneumoniae, Mol. Gen. Genet. 184: 213–217.

    PubMed  CAS  Google Scholar 

  96. Faelen, M., Toussaint, A., and De Lafontaine, J., 1975, Model for the enhancement of X-gal integration into partially induced Mu-1 lysogens, J. Bacteriol. 121: 873–882.

    PubMed  CAS  Google Scholar 

  97. Fayet, O., Ramond, P., Polard, P., Prère, M. E, and Chandler, M., 1990, Functional similarities between retroviruses and the IS3 family of bacterial insertion sequences, Mol. Microbiol. 4: 1771–1777.

    Article  PubMed  CAS  Google Scholar 

  98. Fitzgerald, G. E, and Gasson, M. J., 1988, In vivo gene transfer systems and transposons, Biochimie 70: 489–502.

    CAS  Google Scholar 

  99. Forbes, K. J., and Pérombelon, M. C. M., 1985, Chromosomal mapping in Erwinia carotovora subsp. carotovora with the IncP plasmid R68::Mu, J. Bacteriol. 164: 1110–1116.

    PubMed  CAS  Google Scholar 

  100. Franche, C., Canelo, E., Gauthier, D., and Elmerich, C., 1981, Mobilization of the chromosome of Azospirillum brasilense by plasmid R68–45, FEMS Microbiol. Lett. 10: 199–202.

    Article  Google Scholar 

  101. François, V., Conter, A., and Louarn, J.-M., 1990, Properties of new Escherichia coli Hfr strains constructed by integration of pSC101-derived conjugative plasmids, J. Bacteriol. 172: 1436–1440.

    PubMed  Google Scholar 

  102. Franke, A. E., Dunny, G. M., Brown, B. L., An, E, Oliver, D. R., Damle, S. P., and Clewell, D. B., 1978, Gene transfer in Streptococcus faecalis: Evidence for the mobilization of chromosomal determinants by transmissible plasmids, in: Microbiology-1978 ( D. Schlessinger, ed.), American Society for Microbiology, Washington, D.C., pp. 45–47.

    Google Scholar 

  103. Franklin, N. C., 1971, Illegitimate recombination, in: The Bacteriophage Lambda ( A. D. Hershey, ed.), Cold Spring Harbor Laboratory, Cold Spring Harbor, N. Y., pp. 175–194.

    Google Scholar 

  104. Frey, J., and Bagdasarian, M., 1989, The molecular biology of IncQ plasmids, in: Promiscuous Plasmids of Gram-negative Bacteria ( C. M. Thomas, ed.), Academic Press, London, pp. 79–94.

    Google Scholar 

  105. Fürste, J. P., Pansegrau, W, Ziegelin, G., Kröger, M., and Lanka, E., 1989, Conjugative transfer of promiscuous IncP plasmids: Interaction of plasmid-encoded products with the transfer origin, Proc. Natl. Acad. Sci. USA 86: 1771–1775.

    Article  PubMed  Google Scholar 

  106. Fulbright, D. W., and Leary, J. V, 1978, Linkage analysis of Pseudomonas glycinea, J. Bacteriol. 136: 497–500.

    PubMed  CAS  Google Scholar 

  107. Galas, D. J., and Chandler, M., 1989, Bacterial insertion sequences, in: Mobile DNA ( D. E. Berg and M. M. Howe, eds.), American Society for Microbiology, Washington, D.C., pp. 109–162.

    Google Scholar 

  108. Gennaro, M. L., Kornblum, J., and Novick, R. P., 1987, A site-specific recombination function in Staphylococcus aureus plasmids, J. Bacteriol. 169: 2601–2610.

    PubMed  CAS  Google Scholar 

  109. Gerlitz, M., Hrabak, O., and Schwab, H., 1990, Partitioning of broad-host-range plasmid RP4 is a complex system involving site-specific recombination, J. Bacteriol. 172: 6194–6203.

    PubMed  CAS  Google Scholar 

  110. Ghozlan, H. A., Ahmadian, R. M., Fröhlich, M., Sabry, S., and Kleiner, D., 1991, Genetic tools for Paracoccus denitrificans, FEMS Microbiol. Lett. 82: 303–306.

    Article  CAS  Google Scholar 

  111. Gobius, K. S., and Pemberton, J. M., 1986, Use of plasmid pULBII3 (RP4::mini-Mu) to construct a genomic map of Aeromonas hydrophila, Curr. Microbiol. 13: 111–115.

    Article  CAS  Google Scholar 

  112. Grandgenett, D. P., and Mumm, S. R., 1990, Unraveling retrovirus integration, Cell 60: 3–4.

    Article  PubMed  CAS  Google Scholar 

  113. Griffin, IV T. J., and Kolodner, R. D., 1990, Purification and preliminary characterization of the Escherichia coli K-12 RecF protein, J. Bacteriol. 172: 6291–6299.

    PubMed  CAS  Google Scholar 

  114. Grindley, N. D. E, and Reed, R. R., 1985, Transpositional recombination in prokaryotes, Annu. Rev. Biochem. 54: 863–896.

    Article  PubMed  CAS  Google Scholar 

  115. Grinsted, J., De la Cruz, F., and Schmitt, R., 1990, The Tn21 subgroup of bacterial transposable elements, Plasmid 24: 163–189.

    Article  PubMed  CAS  Google Scholar 

  116. Grinter, N. J., 1981, Analysis of chromosome mobilization using hybrids between plasmid RP4 and a fragment of bacteriophage X carrying ISI, Plasmid 5: 267–276.

    Article  PubMed  CAS  Google Scholar 

  117. Grinter, N. J., 1984, Replication control of IncP plasmids, Plasmid 11: 74–81.

    Article  PubMed  CAS  Google Scholar 

  118. Grinter, N. J., 1984, Replication defective RP4 plasmids recovered after chromosomal integration, Plasmid 11: 65–73.

    Article  PubMed  CAS  Google Scholar 

  119. Groenen, M. A. M., Kokke, M., and van de Putte, P, 1986, Transposition of mini-Mu containing only one of the ends of bacteriophage Mu, EMBO J. 5: 3687–3690.

    PubMed  CAS  Google Scholar 

  120. Groisman, E. A., and Casadaban, M. J., 1986, Mini-Mu bacteriophage with plasmid replicons for in vivo cloning and lac gene fusing, J. Bacteriol. 168: 357–364.

    PubMed  CAS  Google Scholar 

  121. Guiney, D. G., and Lanka, E., 1989, Conjugative transfer of IncP plasmids, in: Promiscuous Plasmids of Gram-negative Bacteria ( C. M. Thomas, ed.), Academic Press, London, pp. 27–56.

    Google Scholar 

  122. Guyer, M., 1978, The yS sequence of F is an insertion sequence, J. Mol. Biol. 126: 347–365.

    Article  PubMed  CAS  Google Scholar 

  123. Guyer, M. S., Reed, R. R., Steitz, J. A., and Low, K. B., 1980, Identification of a sex-factor-affinity site in E. coli as 78, Cold Spring Harbor Symp. Quant. Biol. 45: 135–140.

    Article  Google Scholar 

  124. Haas, D., and Holloway, B. W, 1976, R factor variants with enhanced sex factor activity in Pseudomonas aeruginosa, Mol. Gen. Genet. 144: 243–251.

    Article  PubMed  CAS  Google Scholar 

  125. 125. Haas,D., and Holloway, B. W, 1978, Chromosome mobilization by the R plasmid R68.45: A tool in Pseudomonas genetics, Mol. Gen. Genet. 158:229–237.

    Google Scholar 

  126. Haas, D., and Reimmann, C., 1989, Use of IncP plasmids in chromosomal genetics of gram-negative bacteria, in: Promiscuous Plasmids of Gram-negative Bacteria ( C. M. Thomas, ed.), Academic Press, London, pp. 185–206.

    Google Scholar 

  127. Haas, D., and Riess, G., 1983, Spontaneous deletions of the chromosome-mobilizing plasmid R68.45 in Pseudomonas aeruginosa PAO, Plasmid 9: 42–52.

    Article  PubMed  CAS  Google Scholar 

  128. Haas, D., Watson, J., Krieg, R., and Leisinger, T., 1981, Isolation of an Hfr donor of Pseudomonas aeruginosa PAO by insertion of the plasmid RP1 into the tryptophan synthase gene, Mol. Gen. Genet. 182: 240–244.

    Article  PubMed  CAS  Google Scholar 

  129. Hadley, R. G., and Deonier, C., 1980, Specificity in the formation of Atra F-prime plasmids, J. Bacteriol. 143: 680–692.

    PubMed  CAS  Google Scholar 

  130. 130. Hall, R. M., Brookes, D. E., and Stokes, H. W., 1991, Site-specific insertion of genes into integrons: Role of the 59-base element and determination of the recombination crossover point, Mol. Microbiol. 5:1941–1959.

    Google Scholar 

  131. Haniford, D. B., Chelouche, A. R., and Kleckner, N., 1989, A specific class of ISIO transposase mutants are blocked for target site interactions and promote formation of an excised transposon fragment, Cell 59: 385–394.

    Article  PubMed  CAS  Google Scholar 

  132. Harayama, S., and Rekik, M., 1989, A simple procedure for transferring genes cloned in Escherichia coli vectors into other gram-negative bacteria: Phenotypic analysis and mapping of TOL plasmid gene xy1K, Gene 78: 19–27.

    Article  PubMed  CAS  Google Scholar 

  133. Harayama, S., Tsuda, M., and lino, T., 1980, High frequency mobilization of the chromosome of Escherichia coli by a mutant of plasmid RP4 temperature-sensitive for maintenance, Mol. Gen. Genet. 180: 47–56.

    Article  PubMed  CAS  Google Scholar 

  134. Harayama, S., Oguchi, T., and Iino, T., 1984, Does Tn10 transpose via the cointegrate molecule? Mol. Gen. Genet. 194: 444–450.

    Article  PubMed  CAS  Google Scholar 

  135. Harayama, S., Oguchi, T., and Iino, T., 1984, The E. coli K-12 chromosome flanked by two ISIO sequences transposes, Mol. Gen. Genet. 197: 62–66.

    Article  PubMed  CAS  Google Scholar 

  136. Harayama, S., Lehrbach, P. R., Tsuda, M., Leppik, R., Iino, T., Reineke, W, Knackmuss, H. J., and Timmis, K. N., 1984, Genetic engineering systems for Pseudomonas and their use in the analysis and manipulation of metabolic pathways, in: Transferable Antibiotic Resistance. Plasmids and Gene Manipulation (S. Mitsuhashi and V. Krcméry, eds.), Avicenum Czechoslovak Medical Press, Prague, pp. 361–372.

    Google Scholar 

  137. Hayes, E, Caplice, E., McSweeny, A., Fitzgerald, G. E, and Daly, C., 1990, pAMß1-associated mobilization of proteinase plasmids from Lactococcus lactis subsp. lactis UC317 and L. lactis subsp. cremoris ÚC205, Appl. Environ. Microbiol. 56: 195–201.

    Google Scholar 

  138. Hayes, F, Daly, C., and Fitzgerald, G. E, 1990, High-frequency, site-specific recombination between lactococcal and pAM(31 plasmid DNAs, J. Bacteriol. 172: 3485–3489.

    PubMed  CAS  Google Scholar 

  139. Hayes, W., 1968, The genetics of bacteria and their viruses, Blackwell Scientific Publications, Oxford.

    Google Scholar 

  140. Hecht, D. W, and Malamy, M. H., 1989, Tn4399, a conjugal mobilizing transposon of Bacteroides fragilis, J. Bacteriol. 171: 3603–3608.

    CAS  Google Scholar 

  141. Hecht, D. W, Thompson, J. S., and Malamy, M. H., 1989, Characterization of the termini and transposition products of Tn4399, a conjugal mobilizing transposon of Bacteroides fragilis, Proc. Natl. Acad. Sci. USA 86: 5340–5344.

    Article  PubMed  CAS  Google Scholar 

  142. Hedén, L-O., and Meynell, E., 1976, Comparative study of R1-specific chromosomal transfer in Escherichia coli K-12 and Salmonella typhimurium LT2, J. Bacteriol. 127: 51–58.

    PubMed  Google Scholar 

  143. Hedges, R. W., and Jacob, A. E., 1977, In vivo translocation of genes of Pseudomonas aeruginosa onto a promiscuously transmissible plasmid, FEMS Microbiol. Leu. 2: 15–19.

    Article  CAS  Google Scholar 

  144. Hedges, R. W., Jacob, A. E., and Crawford, I. P., 1977, Wide range plasmid bearing the Pseudomonas aeruginosa tryptophan synthase genes, Nature 267: 283–284.

    Article  PubMed  CAS  Google Scholar 

  145. Herrmann, H., and Günter, E., 1984, High frequency FP2 donor of Pseudomonas aeruginosa PAO, Mol. Gen. Genet. 197: 286–291.

    Article  PubMed  CAS  Google Scholar 

  146. Herrmann, H., Klopotowski, T., and Günter, E., 1986, The Hfr status of Pseudomonas aeruginosa is stabilized by integrative suppression, Mol. Gen. Genet. 204: 519–523.

    Article  PubMed  CAS  Google Scholar 

  147. Herrmann, H., Janke D., Kresja, S., and Roy, M., 1988, In vivo generation of R68.45-pPGH1 hybrid plasmids conferring a Phl+ (meta pathway) phenotype, Mol. Gen. Genet. 214: 173–176.

    Article  PubMed  CAS  Google Scholar 

  148. Hille, J., van Kan, J., Klasen, I., and Schilperoort, R., 1983, Site-directed mutagenesis in Escherichia coli of a stable R772::Ti cointegrate plasmid from Agrobacterium tumefaciens, J. Bacteriol. 154: 693–701.

    PubMed  CAS  Google Scholar 

  149. Hirschel, B. J., Galas, D. J., and Chandler, M., 1982, Cointegrate formation by Tn5, but not transposition, is dependent on recA, Proc. Natl. Acad. Sci. USA 79: 4530–4534.

    Article  PubMed  CAS  Google Scholar 

  150. Holloway, B. W, 1978, Isolation and characterization of an R’ plasmid in Pseudomonas aeruginosa, J. Bacteriol. 133: 1078–1082.

    PubMed  CAS  Google Scholar 

  151. Holloway, B. W, 1979, Plasmids that mobilize bacterial chromosome, Plasmid 2: 1–19.

    Article  PubMed  CAS  Google Scholar 

  152. Holloway, B. W., 1983, Pseudomonas genetics and its application to other bacteria, in: Genetics of Industrial Microorganisms (Y. Ikeda and T. Beppu, eds.), Kodansha Ltd., Tokyo, pp. 41–45.

    Google Scholar 

  153. Holloway, B. W, and Low, K. B., 1987, F-prime and R-prime factors, in: Escherichia coli and Salmonella typhimurium. Cellular and Molecular Biology (F C. Neidhardt, J. L. Ingraham, K. B. Low, B. Magasanik, M. Schaehter, and H. E. Umbarger, eds.), American Society for Microbiology, Washington, D.C., pp. 11451153.

    Google Scholar 

  154. Holloway, B. W, Crowther, C., Dean, H., Hagedorn, J., Holmes, N., and Morgan, A. F.,1982, Integration of plasmids into the Pseudomonas chromosome, in: Drug Resistance in Bacteria (S. Mitsuhashi, ed.), Japan Scientific Societies Press, Tokyo, pp. 231–242.

    Google Scholar 

  155. Holloway, B. W., Kearney, P. P., and Lyon, B. R., 1987, The molecular genetics of Cl utilizing microorganisms—An overview, Antonie van Leeuwenhoek J. Microbiol. 53: 47–53.

    Article  PubMed  CAS  Google Scholar 

  156. Holloway, B. W., O’Hoy, K., and Matsumoto, H., 1987, Pseudomonas aeruginosa PAO, in: Genetic Maps, Vol. 4 (S. J. O’Brien, ed.), Cold Spring Harbor Laboratory, Cold Spring Harbor, pp. 213–221.

    Google Scholar 

  157. Holsters, M., Silva, B., Genetello, C., Engler, G., van Vliet, F., De Block, M., Villarroel, R., van Montagu, M., and Schell, J., 1978, Spontaneous formation of cointegrates of the oncogenic Ti-plasmid and the widehost-range P-plasmid RP4, Plasmid 1: 456–467.

    Article  PubMed  CAS  Google Scholar 

  158. Holsters, M., Silva, B., van Vliet, E, Hemalsteens, J. P., Genetello, C., van Montagu, M., and Schell, J., 1978, In vivo transfer of the Ti-plasmid of Agrobacterium tumefaciens to Escherichia coli, Mol. Gen. Genet. 163: 335–338.

    Article  PubMed  CAS  Google Scholar 

  159. Hooykaas, P. J. J., Klapwijk, P. M., Nuti, M. P., Schilperoort, R. A., and Rörsch, A., 1977, Transfer of the Agrobacterium tumefaciens TI plasmid to avirulent Agrobacteria and to Rhizobium ex planta, J. Gen. Microbiol. 98: 477–484.

    Google Scholar 

  160. Hooykaas, P. J. J., Den Dulk-Ras, H., and Schilperoort, R. A., 1980, Molecular mechanism of Ti plasmid mobilization by R plasmids: Isolation of Ti plasmids with transposon-insertions in Agrobacterium tumefaciens, Plasmid 4: 64–75.

    Article  PubMed  CAS  Google Scholar 

  161. Hooykaas, P. J. J., Den Dulk-Ras, H., and Schilperoort, R. A., 1982, Method for the transfer of large cryptic, non-self-transmissible plasmids: Ex planta transfer of the virulence plasmid of Agrobacterium rhizogenes, Plasmid 8: 94–96.

    Article  PubMed  CAS  Google Scholar 

  162. Hooykaas, P. J. J., Peerbolte, R., Regensburg-Tuink, A. J. G., de Vries, P., and Schilperoort, R. A., 1982, A chromosomal linkage map of Agrobacterium tumefaciens and a comparison with the maps of Rhizobium spp, Mol. Gen. Genet. 188: 12–17.

    Article  CAS  Google Scholar 

  163. Horowitz, B., and Deonier, R. C., 1985, Formation of titra F’ plasmids: Specific recombination at ortT, J. Mol. Bid. 186: 267–274.

    Article  CAS  Google Scholar 

  164. Ichige, A., Matsutani, S., Oishi, K., and Mizushima, S., 1989, Establishment of gene transfer systems for and construction of the genetic map of a marine Vibrio strain, J. Bacteriol. 171: 1825–1834.

    PubMed  CAS  Google Scholar 

  165. Ichikawa, IL, and Ohtsubo, E., 1990, In vitro transposition of transposon Tn3, J. Biol. Chem. 265:1882918832.

    Google Scholar 

  166. lida, S., 1977, Directed integration of an F’ plasmid by integrative suppression, Mol. Gen. Genet. 155: 153–162.

    Article  Google Scholar 

  167. Ikeda, H., Aoki, K., and Naito, A., 1982, Illegitimate recombination mediated in vitro by DNA gyrase of Escherichia coli: Structure of recombinant DNA molecules, Proc. Natl. Acad. Sci. USA 79: 37243728.

    Google Scholar 

  168. Ikeda, H., Kawasaki, I., and Gellert, M., 1984, Mechanism of illegitimate recombination: Common sites for recombination and cleavage mediated by E. coli DNA gyrase, Mol. Gen. Genet. 196: 546–549.

    Article  PubMed  CAS  Google Scholar 

  169. Isberg, R. R., and Syvanen, M., 1985, Tn5 transposes independently of cointegrate resolution: Evidence for an alternative model for transposition, J. Mol. Biol. 182: 69–78.

    Article  PubMed  CAS  Google Scholar 

  170. Jacob, F., and Wollman, E. L., 1956, Recombinaison génétique et mutants de fertilité chez Escherichia coli, Comps. Rend. Acad. Sci. Paris 242: 303–306.

    Google Scholar 

  171. Janus, S., Letouvet-Pawlak, B., Monnier, C., and Guespin-Michel, J. F., 1990, Mechanism of integration of the broad-host-range plasmid RP4 into the chromosome of Myxococcus xanthus, Plasmid 23: 183–193.

    Article  Google Scholar 

  172. Johnson, D. A., 1988, Construction of transposons carrying the transfer function of RP4, Plasmid 20: 249–258.

    Article  PubMed  CAS  Google Scholar 

  173. Johnson, D. A., and Willens, N. S., 1980, Tn2301, a transposon construct carrying the entire transfer region of the F plasmid, J. Bacteriol. 143: 1171–1178.

    PubMed  CAS  Google Scholar 

  174. Johnson, M. S., McClure, M. A., Feng, D.-E, Gray, J., and Doolittle, R. F., 1986, Computer analysis of retroviral pol genes: Assignment of enzymatic functions to specific sequences and homologies with nonviral enzymes, Proc. Natl. Acad. Sci. USA 83: 7648–7652.

    Article  PubMed  CAS  Google Scholar 

  175. Johnson, S. R., and Romig, W. R., 1979, Transposon-facilitated recombination in Vibrio cholerae, Mol. Gen. Genet. 170: 93–101.

    Article  PubMed  CAS  Google Scholar 

  176. Johnston, A. W. B., and Beringer, J. E., 1977, Chromosomal recombination between Rhizobium species, Nature 267: 611–613.

    Article  Google Scholar 

  177. Johnston, A. W. B., Setchell, S. M., and Beringer, J. E., 1978, Interspecific crosses between Rhizobium leguminosarum and R. meliloti: Formation of haploid recombinants and of R-primes, J. Gen. Microbio!. 104: 209–218.

    Google Scholar 

  178. Jones, K. S., Coleman, J., Merkel, G. W, Laue, T M., and Skallca, A. M., 1992, Retroviral integrase functions as a multimer and can turn over catalytically, J. Biol. Chem. 267: 16037–16040.

    PubMed  CAS  Google Scholar 

  179. Julliot, J. S., and Boistard, P., 1979, Use of RP4-prime plasmids constructed in vitro to promote a polarized transfer of the chromosome in Escherichia coli and Rhizobium meliloti, Mol. Gen. Genet. 173: 289–298.

    Article  PubMed  CAS  Google Scholar 

  180. Julliot, J. S., Dusha, I., Renalier, M. H., Terzaghi, B., Gamerone, A. M., and Boistard, P., 1984, An RP4prime containing a 285 kb fragment of Rhizobium meliloti pSym megaplasmid: Structural characterization and utilization for genetic studies of symbiotic functions controlled by pSym, Mol. Gen. Genet. 193: 17–26.

    Article  CAS  Google Scholar 

  181. Kahn, P. L., 1968, Isolation of high-frequency recombining strains from Escherichia coli containing the V colicinogenic factor, J. Bacteriol. 96: 205–214.

    PubMed  CAS  Google Scholar 

  182. 182. Kameneva, S. V., Polivtseva, T. P, Belavina, N. V., and Shestakov, S. V., 1986, Hfr donor of phototrophic nitrogen fixing bacterium Rhodopseudomonas sphaeroides: Localization of mutations in genes controlling nitrogen fixation, Genetika (Russ.) 22:2664–2672.

    Google Scholar 

  183. Kaney, A. R., and Atwood, K. C., 1972, Incompatibility of integrated sex factors in double male strains of Escherichia coli, Genetics 70: 31–39.

    PubMed  CAS  Google Scholar 

  184. Katz, L., Brown, D. P., and Donadio, S., 1991, Site-specific recombination in Escherichia coli between the att sites of plasmid pSE211 from Saccharopolyspora erythraea, Mol. Gen. Genet. 227: 155–159.

    Article  PubMed  CAS  Google Scholar 

  185. Katz, R. A., Merkel, G., Kulkosky, J., Leis, J., and Skalka, A. M., 1990, The avian retroviral IN protein is both necessary and sufficient for integrative recombination in vitro, Cell 63: 87–95.

    Article  PubMed  CAS  Google Scholar 

  186. Khan, E., Mack, J. P. G., Katz, R. A., Kulkowsky, J., and Skalka, A. M., 1991, Retroviral integrase domains: DNA binding and the recognition of LTR sequences, Nucleic Acids Res. 19: 851–860.

    Article  PubMed  CAS  Google Scholar 

  187. Kieser, H. M., Kieser, T, and Hopwood, D. A., 1992, A combined genetic and physical map of the Streptomyces coelicolor A3(2) chromosome, J. Bacteriol. 174: 5496–5507.

    PubMed  CAS  Google Scholar 

  188. Kilbane, J. J., and Malamy, M. H., 1980, F Factor mobilization of non-conjugative chimeric plasmids in Escherichia coli: General mechanisms and a role for site-specific recA-independent recombination at oriVI, J. Mol. Biol. 143: 73–93.

    Article  PubMed  CAS  Google Scholar 

  189. Kiss, G. B., Dobo, K., Dusha, I., Breznovits, A., Orosz, L., Vincze, E., and Kondorosi, A., 1980, Isolation and characterization of an R-prime plasmid from Rhizobium meliloti, J. Bacteriol. 141: 121–128.

    PubMed  CAS  Google Scholar 

  190. Kleckner, N., 1989, Transposon Tn10, in: Mobile DNA ( D. E. Berg and M. M. Howe, eds.), American Society for Microbiology, Washington, D. C., pp. 227–268.

    Google Scholar 

  191. Kleckner, N., Roth, J., and Botstein, D., 1977, Genetic engineering in vivo using translocatable drug-resistance elements: New methods in bacterial genetics, J. Mol. Biol. 116: 125–159.

    Article  PubMed  CAS  Google Scholar 

  192. Klein, S., Lohman, K., Clover, R., Walker, G. C., and Signer, E. R., 1992, A directional, high-frequency chromosomal mobilization system for genetic mapping of Rhizobium meliloti, J. Bacteriol. 174: 324–326.

    PubMed  CAS  Google Scholar 

  193. Koonin, E. V., 1992, DnaC protein contains a modified ATP-binding motif and belongs to a novel family of ATPases including also DnaA, Nucleic Acids Res. 20: 1997.

    Google Scholar 

  194. Kondorosi, A., Kiss, G. B., Forrai, T, Vincze, E., and Banfalvi, Z., 1977, Circular linkage map of Rhizobium meliloti chromosome, Nature 268: 525–527.

    Article  Google Scholar 

  195. Konforti, B. B., and Davis, R. W, 1990, The preference for a 3’ homologous end is intrinsic to RecApromoted strand exchange, J. Biol. Chem. 265: 6916–6920.

    PubMed  CAS  Google Scholar 

  196. Krishnapillai, V, Royle, P., and Lehrer, J., 1981, Insertions of the transposon Tnl into the Pseudomonas aeruginosa chromosome, Genetics 97: 495–511.

    PubMed  CAS  Google Scholar 

  197. Laban, A., and Cohen, A, 1981, Interplasmidic and intraplasmidic recombination in Escherichia coli K-12, Mol. Gen. Genet. 184: 200–207.

    PubMed  CAS  Google Scholar 

  198. Leemans, J., Villarroel, R., Silva, B., Van Montagu, M., and Schell, J., 1980, Direct repetition of a 1.2 Md DNA sequence is involved in site-specific recombination by the PI plasmid R68, Gene 10: 319–328.

    Article  PubMed  CAS  Google Scholar 

  199. Lejeune, P., and Mergeay, M., 1980, R-plasmid-mediated chromosome mobilization in Pseudomonas fluorescens 6.2, Arch. Int. Physiol. Biochim. 88: B289 — B290.

    Google Scholar 

  200. Lejeune, P, Mergeay, M., Van Gijsegem, F., Faelen, M., Gerits, J., and Toussaint, A., 1983, Chromosome transfer and R-prime plasmid formation mediated by plasmid pULB113 (RP4::mini-Mu) in Alcaligenes eutrophus CH34 and Pseudomonas fluorescens 6.2, J. Bacteriol. 155: 1015–1026.

    PubMed  CAS  Google Scholar 

  201. Leonardo, J. M., and Goldberg, R. B., 1980, Regulation of nitrogen metabolism in glutamine auxotrophs of Klebsiella pneumoniae, J. Bacteriol. 142: 99–110.

    PubMed  CAS  Google Scholar 

  202. Lichens-Park, A., and Syvanen, M., 1988, Cointegrate formation by IS50 requires multiple donor molecules, Mol. Gen. Genet. 211: 244–251.

    Article  PubMed  CAS  Google Scholar 

  203. Liu, L., and Berg, C. M., 1990, Mutagenesis of dimeric plasmids by the transposon y8 (Tn1000), J. Bacteriol. 172: 2814–2816.

    PubMed  CAS  Google Scholar 

  204. Lockshon, D., and Morris, D. R., 1985, Sites of reaction of Escherichia coli DNA gyrase on pBR322 in vivo as revealed by oxolinic acid-induced plasmid linearization, J. Mol. Biol. 181: 63–74.

    Article  PubMed  CAS  Google Scholar 

  205. Low, K. B., 1972, Escherichia coli K-12 F-prime factors, old and new, Bacteriol. Rev. 36: 587–607.

    CAS  Google Scholar 

  206. Low, K. B., 1987, Hfr strains of Escherichia coli K-12, in: Escherichia coli and Salmonella typhimurium. Cellular andMolecularBidogy(F C. Neidhardt, J. L. Ingraham, K. B. Low, B. Magasanik, M. Schaechter, and E. Umbarger, eds.), American Society for Microbiology, Washington, D.C., pp. 1134–1137.

    Google Scholar 

  207. Luisi-DeLuca, C., Lovett, S. T., and Kolodner, R. D., 1989, Genetic and physical analysis of plasmid recombination in recB recC sbcB and recB recC sbcA Escherichia coli K-12 mutants, Genetics 122: 269–278.

    PubMed  CAS  Google Scholar 

  208. Lycett, G. W, and Pritchard, R. H., 1986, Functioning of the F-plasmid origin of replication in an Escherichia coli K12 Hfr strain during exponential growth, Plasmid 16: 168–174.

    Article  PubMed  CAS  Google Scholar 

  209. Machida, Y., Machida, C., and Ohtsubo, E., 1982, A novel type of transposon generated by insertion element IS102 present in a pSC101 derivative, Cell 30: 29–36.

    Article  PubMed  CAS  Google Scholar 

  210. Magnin, J.-P., 1987, Isolement d’une souche Hfr de la bactérie photosynthetique Rhodobacter capsulatus et cartographie du chromosome, Ph.D. Thesis, Université de Grenoble.

    Google Scholar 

  211. Manis, J., Kopecko, D., and Kline, B., 1980, Cloning of a Lack BamHI fragment into transposon Tn3 and transposition of the Tn3(lac) element, Plasmid 4: 170–174.

    Article  PubMed  CAS  Google Scholar 

  212. Marrs, B., 1981, Mobilization of the genes for photosynthesis from Rhodopseudomonas capsulata by a promiscuous plasmid, J. Bacteriol. 146: 1003–1012.

    PubMed  CAS  Google Scholar 

  213. Martin, R. R., Thorlton, C. L., and Unger, L., 1981, Formation of Escherichia coli Hfr strains by integrative suppression with the P group plasmid RP1, J. Bacteriol. 145: 713–721.

    PubMed  CAS  Google Scholar 

  214. Martinez, E., and de la Cruz, F., 1990, Genetic elements involved in Tn21 site-specific integration, a novel mechanism for the dissemination of antibiotic resistance genes, EMBO J. 9: 1275–1281.

    PubMed  CAS  Google Scholar 

  215. Marvo, S. L., King, S. R., and Jaskunas, R. R., 1983, Role of short regions of homology in intermolecular illegitimate recombination events, Proc. Natl. Acad. Sci. USA 80: 2452–2456.

    Article  PubMed  CAS  Google Scholar 

  216. Matsutani, S., Ohtsubo, H., Maeda, Y., and Ohtsubo, E., 1987, Isolation and characterization of IS elements repeated in the bacterial chromosome, J. Mol. Biol. 196: 445–455.

    Article  PubMed  CAS  Google Scholar 

  217. Mazodier, P., Petter, R., and Thompson, C., 1989, Intergeneric conjugation between Escherichia coli and Streptomyces species, J. Bacteriol. 171: 3583–3585.

    PubMed  CAS  Google Scholar 

  218. Mazodier, P., and Davies, J., 1991, Gene transfer between distantly related bacteria, Annu. Rev. Genet. 25: 147–171.

    Article  PubMed  CAS  Google Scholar 

  219. McCormick, M., Wishart, W, Ohtsubo, H., Heffron, F., and Ohtsubo, E., 1981, Plasmid cointegrates and their resolution mediated by transposon Tn3 mutants, Gene 15: 103–118.

    Article  PubMed  CAS  Google Scholar 

  220. McLaughlin, W, and Ahmad, M. H., 1986, Transfer of plasmids RP4 and R68.45 and chromosomal mobilization in cowpea rhizobia, Arch. Microbiol. 144: 408–411.

    Article  CAS  Google Scholar 

  221. Meade, H. M., and Signer, E. R., 1977, Genetic mapping of Rhizobium meliloti, Proc. Natl. Acad. Sci. USA 74: 2076–2078.

    Article  PubMed  CAS  Google Scholar 

  222. Megias, M., Caviedes, M. A., Palomares, A. J., and Perez-Silva, J., 1982, Use of plasmid R68.45 for constructing a circular linkage map of the Rhizobium trifolii chromosome, J. Bacteriol. 149: 59–64.

    PubMed  CAS  Google Scholar 

  223. Menou, G., Mahillon, J., Lecadet, M. M., and Lereclus, D., 1990, Structural and genetic organization of 15232, a new insertion sequence of Bacillus thuringiensis, J. Bacteriol. 172: 6689–6696.

    PubMed  CAS  Google Scholar 

  224. Mercenier, A., and Chassy, B. M., 1988, Strategies for the development of bacterial transformation systems, Biochimie 70: 503–517.

    Article  PubMed  CAS  Google Scholar 

  225. Mergeay, M., Lejeune, P., Sadouk, A., Gerits, J., and Fabry, L., 1987, Shuttle transfer (or retrotransfer) of chromosomal markers mediated by plasmid pULB113, Mol. Gen. Genet. 209: 61–70.

    Article  PubMed  CAS  Google Scholar 

  226. Meyer, R., 1989, Site-specific recombination at oriT of plasmid R1162 in the absence of conjugative transfer, J. Bacteriol. 171: 799–806.

    PubMed  CAS  Google Scholar 

  227. 227. Michel, B., Niaudet, B., and Ehrlich, S. D., 1983, Intermolecular recombination during transformation of Bacillus subtilis competent cells by monomeric and dimeric plasmids, Plasmid 10:1–10.

    Google Scholar 

  228. Miller, I. S., Fox, D., Saeed, N., Borland, P. A., Miles, C. A., and Sastry, G. R. K., 1986, Enlarged map of Agrobacterium tumefaciens C58 and the location of chromosomal regions which affect tumorigenicity, Mol. Gen. Genet. 205: 153–159.

    Article  CAS  Google Scholar 

  229. Miller, J. H., 1992, A Short Course in Bacterial Genetics, Cold Spring Harbor Laboratory Press, Plainview, N.Y., pp. 2. 1–2. 67.

    Google Scholar 

  230. Miller, R. V., and Kokjohn, T. A., 1990, General microbiology of recA: Environmental and evolutionary significance, Annu. Rev. Microbiol. 44: 365–394.

    Article  PubMed  CAS  Google Scholar 

  231. Mills, D., 1985, Transposon mutagenesis and its potential for studying virulence genes in plant pathogens, Annu. Rev. Phytopathol. 23: 297–320.

    Article  CAS  Google Scholar 

  232. Miura-Masuda, A., and Ikeda, H., 1990, The DNA gyrase of Escherichia coli participates in the formation of a spontaneous deletion by recA-independent recombination in vivo, Mol. Gen. Genet. 220: 345–352.

    Article  PubMed  CAS  Google Scholar 

  233. Mizuuchi, K., 1992, Transpositional recombination: Mechanistic insights from studies of Mu and other elements, Annu. Rev. Biochem. 61: 1011–1051.

    Article  PubMed  CAS  Google Scholar 

  234. Mötsch, S., and Schmitt, R., 1984, Replicon fusion mediated by a single-ended derivative of transposon Tn1721, Mol. Gen. Genet. 195: 281–287.

    Article  PubMed  Google Scholar 

  235. Mötsch, S., Schmitt, R., Avila, P., de la Cruz, F, Ward, E., and Grinsted, J., 1985, Junction sequences generated by “one-ended transposition,” Nucleic Acids Res. 13: 3335–3342.

    Article  PubMed  Google Scholar 

  236. Moody, E. E. M., and Runge, R., 1972, The integration of autonomous transmissible plasmids into the chromosome of Escherichia coli K12, Genet. Res. (Camb.) 19: 181–186.

    Article  CAS  Google Scholar 

  237. Moore, A. T, Nayudu, M., and Holloway, B. W, 1983, Genetic mapping in Methylophilus methylotrophus AS1, J. Gen. Microbiol. 129: 785–799.

    PubMed  CAS  Google Scholar 

  238. Morgan, A. F, 1982, Isolation and characterization of Pseudomonas aeruginosa R’ plasmids constructed by interspecific mating, J. Bacteriol. 149: 654–661.

    PubMed  CAS  Google Scholar 

  239. Müller, B., Jones, C., Kemper, B., and West, S. C., 1990, Enzymatic formation and resolution of Holliday junctions in vitro, Cell 60: 329–336.

    Article  PubMed  Google Scholar 

  240. Nag, D. K., DasGupta, U., Adelt, G., and Berg, D. E., 1985, IS50-mediated inverse transposition: Specificity and precision, Gene 34: 17–26.

    Article  PubMed  CAS  Google Scholar 

  241. Naito, A., Naito, S., and Ikeda, H., 1984, Homology is not required for recombination mediated by DNA gyrase of Escherichia coli, Mol. Gen. Genet. 193: 238–243.

    Article  CAS  Google Scholar 

  242. Nakazawa, T, Hayashi, E., Yokota, T, Ebina, Y., and Nakazawa, A., 1978, Isolation of TOL and RP4 recombinants by integrative suppression, J. Bacteriol. 134: 270–277.

    PubMed  CAS  Google Scholar 

  243. Nakazawa, T, Inouye, S., and Nakazawa, A., 1980, Physical and functional mapping of RP4-TOL plasmid recombinants: Analysis of insertion and deletion mutants, J. Bacteriol. 144: 222–231.

    PubMed  CAS  Google Scholar 

  244. Nakazawa, T, Kimoto, M., and Abe, M., 1990, Cloning, sequencing, and transcriptional analysis of the recA gene of Pseudomonas cepacia, Gene 94: 83–88.

    Article  CAS  Google Scholar 

  245. Nassif, X., Fournier, J-M., Arondel, J., and Sansonetti, P. J., 1989, Mucoid phenotype of Klebsiella pneumoniae is a plasmid-encoded virulence factor, Infect. Immun. 57: 546–552.

    PubMed  CAS  Google Scholar 

  246. Nayudu, M., and Holloway, B. W, 1981, Isolation and characterization of R-plasmid variants with enhanced chromosomal mobilization ability in Escherichia coli K-12, Plasmid 6: 53–66.

    Article  PubMed  CAS  Google Scholar 

  247. Nishimura, Y., Caro, L., Berg, C. M., and Hirota, Y., 1971, Chromosome replication in Escherichia coli. IV. Control of chromosome replication and cell division by an integrated episome, J. Mol. Biol. 55: 441–456.

    Article  PubMed  CAS  Google Scholar 

  248. Nishimura, A., Nishimura, Y., and Caro, L., 1973, Isolation of Hfr strains from R+ and ColV2+ strains of Escherichia coli and derivation of an R’ lac factor by transduction, J. Bacteriol. 116: 1107–1112.

    PubMed  CAS  Google Scholar 

  249. Nordeen, R. O., and Holloway, B. W, 1990, Chromosome mapping in Pseudomonas syringae pv syringae strain PS224, J. Gen. Microbiol. 136: 1231–1239.

    PubMed  CAS  Google Scholar 

  250. Novick, R. P., Clowes, R. C., Cohen, S. N., Curtiss, III, R., Dana, N., and Falkow, S., 1976, Uniform nomenclature for bacterial plasmids: A proposal, Bacteriol. Rev. 40: 168–189.

    CAS  Google Scholar 

  251. Okahashi, N., Sasakawa, C., Okada, N., Yamada, M., Yoshikawa, M., Tokuda, M., Takahashi, I., and Koga, T, 1990, Construction of a Notl restriction map of the Streptococcus mutans genome, J. Gen. Microbiol. 136: 2217–2223.

    PubMed  CAS  Google Scholar 

  252. Olasz, F, and Arber, W, 1989, A model for IS30-mediated transposition in E. coli, Experientia 45: A39.

    Google Scholar 

  253. O’Connor, M. B., and Malamy, H. M., 1984, Role of the F factor oriVI region in recA-independent illegitimate recombination: Stable replicon fusions of the F derivative pOX38 and pBR322-related plasmids, J. Mol. Biol. 175: 263–284.

    Article  PubMed  Google Scholar 

  254. O’Connor, M. B., and Malamy, M. H., 1985, Mapping of DNA gyrase cleavage sites in vivo: Oxolinic acid induced cleavages in plasmid pBR322, J. Mol. Biol. 181:545.-550.

    Google Scholar 

  255. O’Connor, M. B., Kilbane, J. J., and Malamy, M. H., 1986, Site-specific and illegitimate recombination in the oriV1 region of the F factor: DNA sequences involved in recombination and resolution, J. Mol. Bid. 189: 85–102.

    Article  Google Scholar 

  256. O’Hoy, K., 1987, Genetic and physical analysis of the Pseudomonas aeruginosa PAO chromosome, Ph.D. Thesis, Monash University, Melbourne, Australia.

    Google Scholar 

  257. O’Hoy, K., and Krishnapillai, V., 1985, Transposon mutagenesis of the Pseudomonas aeruginosa PAO chromosome and the isolation of high frequency of recombination donors, FEMS Microbiol. Lett. 29: 299–303.

    Article  Google Scholar 

  258. O’Hoy, K., and Krishnapillai, V., 1987, Recalibration of the Pseudomonas aeruginosa strain PAO chromosome map in time units using high-frequency-of-recombination donors, Genetics 1. 15: 611–618.

    Google Scholar 

  259. Pansegrau, W, Miele, L., Lutz, R., and Lanka, E., 1987, Nucleotide sequence of the kanamycin resistance determinant of plasmid RP4: Homology to other aminoglycoside 3’-phosphotransferases, Plasmid 18: 193–204.

    Article  PubMed  CAS  Google Scholar 

  260. Pearce, L. E., and Meynell, E., 1968, Specific chromosomal affinity of a resistance factor, J. Gen. Microbiol. 50: 159–172.

    PubMed  CAS  Google Scholar 

  261. Pemberton, M. J., and Bowen, A. R. S. G., 1981, High-frequency chromosome transfer in Rhodopseudomonas sphaeroides promoted by broad-host-range plasmid RP1 carrying mercury transposon Tn501, J. Bacteriol. 147: 110–117.

    PubMed  CAS  Google Scholar 

  262. Perkins, J. B., and Youngman, P. J., 1984, A physical and functional analysis of Tn917, a Streptococcus transposon in the Tn3 family that functions in Bacillus, Plasmid 12: 119–138.

    Article  CAS  Google Scholar 

  263. Peterson, B. C., Hashimoto, H., and Rownd, R. H., 1982, Cointegrate formation between homologous plasmids in Escherichia coli, J. Bacteriol. 151: 1086–1094.

    CAS  Google Scholar 

  264. Pischl, D. L., and Farrand, S. K., 1983, Transposon-facilitated chromosome mobilization in Agrobacterium tumefaciens, J. Bacteriol. 153: 1451–1460.

    CAS  Google Scholar 

  265. Pittard, J., Loutit, J. S., and Adelberg, E. A., 1963, Gene transfer by F’ strains of Escherichia coli K-12, J. Bacteriol. 85: 1394–1401.

    PubMed  CAS  Google Scholar 

  266. Plasota, M., Piechucka, E., Kauc, B., and Wlodarczyk, M., 1984, R68.45 plasmid mediated conjugation in Thiobacillus A2, Microbios 41: 81–89.

    PubMed  CAS  Google Scholar 

  267. Plasterk, R. H. A., 1991, Frameshift control of IS1 transposition, Trends Genet. 7: 203–204.

    PubMed  CAS  Google Scholar 

  268. Prère, M.-F., Chandler, M., and Fayet, 0., 1990, Transposition in Shigella dysenteriae: Isolation and analysis of IS911, a new member of the IS3 group of insertion sequences, J. Bacteriol. 172: 4090–4099.

    PubMed  Google Scholar 

  269. Priebe, S. D., and Lacks, S. A., 1989, Region of the streptococcal plasmid pMV158 required for conjugative mobilization, J. Bacteriol. 171: 4778–4784.

    PubMed  CAS  Google Scholar 

  270. Priefer, U. B., 1989, Genes involved in lipopolysaccharide production and symbiosis are clustered on the chromosome of Rhizobium leguminosarum biovar viciae VF39, J. Bacteriol. 171: 6161–6168.

    PubMed  CAS  Google Scholar 

  271. Ratnaningsih, E., Dharmsthiti, S., Krishnapillai, V., Morgan, A., Sinclair, M., and Holloway, B. W., 1990, A combined physical and genetic map of Pseudomonas aeruginosa PAO, J. Gen. Microbiol. 136: 2351–2357.

    PubMed  CAS  Google Scholar 

  272. Read, H. A., Sarnia, S. D., and Jaskunas, S. R., 1980, Fate of donor insertion sequence IS1 during transposition, Proc. Natl. Acad. Sci. USA 77: 2514–2518.

    Article  PubMed  CAS  Google Scholar 

  273. Reimmann, C., and Haas, D., 1986, IS21 insertion in the trfA replication control gene of chromosomally integrated plasmid RPI: A property of stable Pseudomonas aeruginosa Hfr strains, Mol. Gen. Genet. 203: 511–519.

    Article  PubMed  CAS  Google Scholar 

  274. Reimmann, C., and Haas, D., 1987, Mode of replicon fusion mediated by the duplicated insertion sequence IS21 in Escherichia coli, Genetics 115: 619–625.

    CAS  Google Scholar 

  275. Reimmann, C., and Haas, D., 1990, The istA gene of insertion sequence IS21 is essential for cleavage at the inner 3’ ends of tandemly repeated IS21 elements in vitro, EMBO J. 9: 4055–4063.

    CAS  Google Scholar 

  276. Reimmann, C., Rella, M., and Haas, D., 1988, Integration of replication-defective R68.45-like plasmids into the Pseudomonas aeruginosa chromosome, J. Gen. Microbiol. 134: 1515–1523.

    PubMed  CAS  Google Scholar 

  277. Reimmann, C., Moore, R., Little, S., Savioz, A., Willens, N. S., and Haas, D., 1989, Genetic structure, function and regulation of the transposable element IS21, Mol. Gen. Genet. 215: 416–424.

    Article  PubMed  CAS  Google Scholar 

  278. Riess, G., Holloway, B. W, and Pühler, A., 1980, R68.45, a plasmid with chromosome mobilizing ability (Cma) carries a tandem duplication, Genet. Res. (Camb.) 36: 99–109.

    Article  CAS  Google Scholar 

  279. Riess, G., Masepohl, B., and Pühler, A., 1983, Analysis of IS21-mediated mobilization of plasmid pACYC184 by R68.45 in Escherichia coli, Plasmid 10: 111–118.

    CAS  Google Scholar 

  280. Romero, D. A., Slos, P., Robert, C., Castellino, I., and Mercenier, A., 1987, Conjugative mobilization as an alternative vector delivery system for lactic streptococci, Appl. Environ. Microbiol. 53: 2405–2413.

    PubMed  CAS  Google Scholar 

  281. Rosner, J. L., and Guyer, M. S., 1980, Transposition of ISI-XBIO-ISI from a bacteriophage k derivative carrying the ISI-cat-ISI transposon (Tn9), Mol. Gen. Genet. 178: 111–120.

    Article  PubMed  CAS  Google Scholar 

  282. Sanderson, K. E., and MacLachlan, P R., 1987, F-mediated conjugation, F+ strains, and Hfr strains of Salmonella typhimurium and Salmonella abony, in: Escherichia coli and Salmonella typhimurium. Cellular and Molecular Biology, Vol. 2 ( E. C. Neidhardt, J. L. Ingraham, K. B. Low, B. Magasanik, M. Schaechter, and H. E. Umbarger, eds.), American Society for Microbiology, Washington, D. C., pp. 1138–1144.

    Google Scholar 

  283. Sanderson, K. E., Ross, H., Ziegler, L., and Miceli, P. H., 1972, F+, Hfr, and F’ strains of Salmonella typhimurium and Salmonella abony, Bacteriol. Rev. 36: 608–637.

    CAS  Google Scholar 

  284. Sano, Y., and Kageyama, M., 1984, Genetic determinant of pyocin AP41 as an insert in the Pseudomonas aeruginosa chromosome, J. Bacteriol. 158: 562–570.

    PubMed  CAS  Google Scholar 

  285. Scaife, J., and Gross, J. D., 1963, The mechanism of chromosome mobilization by an F-prime factor in Escherichia coli K12, Genet. Res. (Camb.) 4: 328–331.

    Article  Google Scholar 

  286. Schäfer, A., Kalinowski, J., Simon, R., Seep-Feldhaus, A-H., and Pühler, A., 1990, High-frequency conjugal plasmid transfer from gram-negative Escherichia coli to various gram-positive coryneform bacteria, J. Bacteriol. 172: 1663–1666.

    PubMed  Google Scholar 

  287. Schmitt, R., Mötsch, S., Rogowsky, P., de la Cruz, F, and Grinsted, J., 1985, On the transposition and evolution of Tn./721 and its relatives, in: Plasmids in Bacteria ( D. R. Helinski, S. N. Cohen, D. B. Clewell, D. A. Jackson, and A. Hollaender, eds.), Plenum Press, New York, pp. 79–91.

    Chapter  Google Scholar 

  288. Schoonejans, E., and Toussaint, A., 1983, Utilization of plasmid pULB1I3 (RP4::mini-Mu) to construct a linkage map of Erwinia carotovora subsp. chrysanthemi, J. Bacteriol. 154: 1489–1492.

    CAS  Google Scholar 

  289. Schurter, W., and Holloway, B. W, 1986, Genetic analysis of promoters on the insertion sequence IS21 of plasmid R68.45, Plasmid 15: 8–18.

    Article  PubMed  CAS  Google Scholar 

  290. Seeberg, A. H., and Wiedemann, B., 1984, Transfer of the chromosomal bla gene from Enterobacter cloacae to Escherichia coli by RP4::mini-Mu, J. Bacteriol. 157: 89–94.

    PubMed  CAS  Google Scholar 

  291. Serebrijski, I. G., Kazakova, S. M., and Tsygankov, Y. D., 1989, Construction of Hfr-like donors of the obligate methanol-oxidizing bacterium Methylobacillus flagellatum KT, FEMS Microbiol. Lett. 59: 203–206.

    Article  Google Scholar 

  292. Shah, K. S., Kuykendall, L. D., and Kim, C.-H., 1989, R-prime plasmids from Bradyrhizobium japonicum and Rhizobium fredii, Arch. Microbiol. 152: 550–555.

    Article  CAS  Google Scholar 

  293. Shen, P., and Huang, H. V, 1986, Homologous recombination in Escherichia coli: Dependence on substrate length and homology, Genetics 112: 441–457.

    PubMed  CAS  Google Scholar 

  294. Sherman, P. A., and Fyfe, J. A., 1990, Human immunodeficiency virus integration protein expressed in Escherichia coli possesses selective DNA cleaving activity, Proc. Natl. Acad. Sci. USA 87: 5119–5123.

    Article  CAS  Google Scholar 

  295. Sherratt, D., 1989, Tn3 and related transposable elements: Site-specific recombination and transposition, in: Mobile DNA ( D. E. Berg and M. M. Howe, eds.), American Society for Microbiology, Washington, D. C., pp. 163–184.

    Google Scholar 

  296. Shinomiya, T., Shiga, S., Kikuchi, A., and Kageyama, M., 1983, Genetic determinant of pyocin R2 in Pseudomonas aeruginosa PAO: II. Physical characterization of pyocin R2 genes using R-prime plasmids constructed from R68.45, Mol. Gen. Genet. 189: 382–389.

    Article  PubMed  CAS  Google Scholar 

  297. Simon, R., 1984, High frequency mobilization of gram-negative bacterial replicons by the in vitro constructed Tn5-Mob transposon, Mol. Gen. Genet. 196: 413–420.

    Article  PubMed  CAS  Google Scholar 

  298. Simon, R., Priefer, U., and Pühler, A., 1983, A broad host range mobilization system for in vivo genetic engineering: Transposon mutagenesis in gram-negative bacteria, BiolTechnology 1: 784–790.

    Article  CAS  Google Scholar 

  299. Simon, R., O’Connell, M., Labes, M., and Pühler, A., 1986, Plasmid vectors for the genetic analysis and manipulation of rhizobia and other gram-negative bacteria, Meth. Enzymol. 118: 640–659.

    Article  PubMed  CAS  Google Scholar 

  300. Simon, R., Quandt, J., and Klipp, W, 1989, New derivatives of transposon Tn5 suitable for mobilization of replicons, generation of operon fusions and induction of genes in gram-negative bacteria, Gene 80: 161–169.

    Article  PubMed  CAS  Google Scholar 

  301. Sistrom, W. R., 1977, Transfer of chromosomal genes mediated by plasmid R68.45 in Rhodopseudomonas sphaeroides, J. Bacteriol. 131: 526–532.

    CAS  Google Scholar 

  302. Skotnicki, M. L., Warr, R. G., Goodman, A. E., and Rogers, P. L., 1983, Development of genetic

    Google Scholar 

  303. techniques and strain improvement in Zymomonas mobilis in: Genetics of Industrial Microorganisms (Y. Ikeda and T. Beppu, eds.), Kodansha Ltd., Tokyo, pp. 361–365.

    Google Scholar 

  304. Smith, C. J., Coote, J. G., and Parton, R., 1986, R-plasmid-mediated chromosome mobilization in Bordetella pertussis, J. Gen. Microbiol. 132: 2685–2692.

    CAS  Google Scholar 

  305. Smith, C. L., and Condemine, G., 1990, New approaches for physical mapping of small genomes, J. Bacteriol. 172: 1167–1172.

    PubMed  CAS  Google Scholar 

  306. Smith, G. R., 1988, Homologous recombination in procaryotes, Microbiol. Rev. 52: 1–28.

    PubMed  CAS  Google Scholar 

  307. Smith, G. R., 1991, Conjugational recombination in E. coli: Myths and mechanisms, Cell 64: 19–27.

    Article  PubMed  CAS  Google Scholar 

  308. Smith, M. D., and Clewell, D. B., 1984, Return of Streptococcus faecalis DNA cloned in Escherichia coli to its original host via transformation of Streptococcus sanguis followed by conjugative mobilization, J. Bacteriol. 160: 1109–1114.

    PubMed  CAS  Google Scholar 

  309. Soldati, L., Crockett, R., Carrigan, J. M., Leisinger, T., Holloway, B. W, and Haas, D., 1984, Revised locations of the his’ and pru (praline utilization) genes on the Pseudomonas aeruginosa chromosome map, Mol. Gen. Genet. 193: 431–436.

    Article  PubMed  CAS  Google Scholar 

  310. Sosio, M., Madon, J., and Hütter, R., 1989, Excision of pä408 from the chromosome of Streptomyces glaucescens and its transfer into Streptomyces lividans, Mol. Gen. Genet. 218: 169–176.

    Article  CAS  Google Scholar 

  311. Sotomura, M., and Yoshikawa, M., 1975, Reinitiation of chromosome replication in the presence of chloramphenicol under an integratively suppressed state by R6K, J. Bacteriol. 122: 623–628.

    PubMed  CAS  Google Scholar 

  312. Spielmann-Ryser, J., Moser, M., Kast, P., and Weber, H., 1991, Factors determining the frequency of plasmid cointegrate formation mediated by insertion sequence ‘S3 from Escherichia coli, Mol. Gen. Genet. 226: 441–448.

    CAS  Google Scholar 

  313. Srivastava, R., Sinha, V. B., and Srivastava, B. S., 1989, Chromosomal transfer and in vivo cloning of genes in Vibrio cholerae using RP4::mini-Mu, Gene 75: 253–259.

    Article  PubMed  CAS  Google Scholar 

  314. Steele, J. L., and McKay, L. L., 1989, Conjugal transfer of genetic material in lactococci: A review, J. Dairy Sci. 72: 3388–3397.

    Article  Google Scholar 

  315. Stewart, G. J., and Carlson, C. A., 1986, The biology of natural transformation, Annu. Rev. Microbiol. 40: 211–235.

    Article  PubMed  CAS  Google Scholar 

  316. Stout, V. G., and landolo, J. J., 1990, Chromosomal gene transfer during conjugation by Staphylococcus aureus is mediated by transposon-facilitated mobilization, J. Bacteriol. 172: 6148–6150.

    PubMed  CAS  Google Scholar 

  317. Strom, A. D., Hirst, R., Petering, J., and Morgan, A., 1990, Isolation of high frequency of recombination donors from Tn5 chromosomal mutants of Pseudomonas putida PPN and recalibration of the genetic map, Genetics 126: 497–503.

    PubMed  CAS  Google Scholar 

  318. Summers, D. K., and Withers, H. L., 1990, Electrotransfer: Direct transfer of bacterial plasmid DNA by electroporation, Nucleic Acids Res. 18: 2192.

    Article  PubMed  CAS  Google Scholar 

  319. Suwanto, A., and Kaplan, S., 1989, Physical and genetic mapping of the Rhodobacter sphaeroides 2.4.1 genome: Presence of two unique circular chromosomes, J. Bacteriol. 171: 5850–5859.

    PubMed  CAS  Google Scholar 

  320. Suwanto, A., and Kaplan, S., 1992, Chromosome transfer in Rhodobacter sphaeroides: Hfr formation and genetic evidence for two unique circular chromosomes, J. Bacteriol. 174: 1135–1145.

    PubMed  CAS  Google Scholar 

  321. Tatra, P. K., and Goodwin, P. M., 1983, R-plasmid-mediated chromosome mobilization in the facultative methylotroph Pseudomonas AMI, J. Gen. Microbiol. 129: 2629–2632.

    CAS  Google Scholar 

  322. Taylor, A. F., 1992, Movement and resolution of Holliday junctions by enzymes from E. coli, Cell 69: 1063 1065.

    Google Scholar 

  323. Terawaki, Y., Kishi, H., and Nakaya, R., 1975, Integration of R plasmid Rtsl to the gal region of the Escherichia coli chromosome, J. Bacteriol. 121: 857–862.

    PubMed  CAS  Google Scholar 

  324. Thompson, T. L., Centola, M. B., and Deonier, R. C., 1989, Location of the nick at oriT of the F plasmid, J. Mol. Biol. 207: 505–512.

    Article  PubMed  CAS  Google Scholar 

  325. Tomcsanyi, T, Berg, C. M., Phadnis, S. H., and Berg, D. E., 1990, Intramolecular transposition by a synthetic IS50 (Tn5) derivative, J. Bacteriol. 172: 6348–6354.

    PubMed  CAS  Google Scholar 

  326. Torres, O. R., Korman, R. Z., Zahler, S. A., and Dunny, G. M., 1991, The conjugative transposon Tn925: Enhancement of conjugal transfer by tetracycline in Enterococcus faecalis and mobilization of chromosomal genes in Bacillus subtilis and E. faecalis, Mol. Gen. Genet. 225: 395–400.

    CAS  Google Scholar 

  327. Tortolero, M., Santero, E., and Casadesus, J., 1983, Plasmid transfer and mobilization of nif markers in Azotobacter vinelandii, Microbios Lett. 22: 31–35.

    Google Scholar 

  328. Towner, K. J., 1978, Chromosome mapping in Acinetobacter calcoaceticus, J. Gen. Microbiol. 104: 175–180.

    CAS  Google Scholar 

  329. Towner, K. J., and Vivian, A., 1977, Plasmids capable of transfer and chromosome mobilization in Acinetobacter calcoaceticus, J. Gen. Microbiol. 101: 167–171.

    CAS  Google Scholar 

  330. Trieu-Cuot, P., Carlier, C., Martin, P., and Courvalin, P., 1987, Plasmid transfer by conjugation from Escherichia coli to gram-positive bacteria, FEMS Microbiol. Lett. 48: 289–294.

    Article  CAS  Google Scholar 

  331. Trieu-Cuot, P, Carlier, C., and Courvalin, P,1988, Conjugative plasmid transfer from Enterococcus faecalis to Escherichia coli, J. Bacteriol. 170:4388–4391.

    Google Scholar 

  332. Tsygankov, Y. D., Kazakova, S. M., and Serebrijski, I. G., 1990, Genetic mapping of the obligate methylotroph Methylobacillus flagellatum: Characteristics of prime plasmids and mapping of the chromosome in time-of-entry units, J. Bacteriol. 172: 2747–2754.

    PubMed  CAS  Google Scholar 

  333. Tucker, W. T., and Pemberton, J. M., 1979, Conjugation and chromosome transfer in Rhodopseudomonas sphaeroides mediated by W and P group plasmids, FEMS Microbiol. Leu. 5: 173–176.

    Article  Google Scholar 

  334. Umeda, M., and Ohtsubo, E., 1989, Mapping of insertion elements ISJ, IS2 and IS3 on the Escherichia coli K-12 chromosome, J. Mol. Biol. 208: 601–614.

    Article  PubMed  CAS  Google Scholar 

  335. Van Gijsegem, F., and Toussaint, A., 1982, Chromosome transfer and R-prime formation by an RP4::miniMu derivative in Escherichia coli, Salmonella typhimurium, Klebsiella pneumoniae, and Proteus mirabilis, Plasmid 7: 30–44.

    Article  Google Scholar 

  336. Van Larebeke, N., Genetello, Ch., Hernaisteens, J. P, De Picker, A., Zaenen, I., Messen; E., Van Montagu, M., and Schell, J., 1977, Transfer of Ti plasmids between Agrobacterium strains by mobilisation with the conjugative plasmid RP4, Mol. Gen. Genet. 152: 119–124.

    Google Scholar 

  337. Van de Putte, P., and Gruijthuijsen, M., 1972, Chromosome mobilization and integration of F factors in the chromosome of recA strains of E. coli under the influence of bacteriophage Mu-1, Mol. Gen. Genet. 118: 173–183.

    Article  PubMed  Google Scholar 

  338. Van der Lelie, D., Bron, S., Venema, G., and Oskam, L., 1989, Similarity of minus origins of replication and flanking open reading frames of plasmids pUB110, pTB913 and pMV158, Nucleic Acids Res. 17: 7283–7294.

    Article  PubMed  Google Scholar 

  339. Van der Lelie, D., Wdsten, H. A. B., Bron, S., Oskam, L., and Venema, G., 1990, Conjugal mobilization of streptococcal plasmid pMV158 between strains of Lactococcus lactis subsp. lactis, J. Bacterial. 172: 42–52.

    Google Scholar 

  340. Varmus, H., and Brown, P., 1989, Retroviruses, in: Mobile DNA ( D. E. Berg and M. M. Howe, eds.), American Society for Microbiology, Washington, D. C., pp. 53–108.

    Google Scholar 

  341. Vivian, A., 1987, Acinetobacter calcoaceticus, in: Genetic Maps, Vol. 4 (S. J. O’Brien, ed.), Cold Spring Harbor Laboratory, Cold Spring Harbor, N. Y., pp. 240–241.

    Google Scholar 

  342. Warren, G., and Sherratt, D., 1977, Complementation of transfer deficient ColE1 plasmids, Mol. Gen. Genet. 151: 197–201.

    Article  PubMed  CAS  Google Scholar 

  343. Watson, J. M., and Holloway, B. W, 1978, Chromosome mapping in Pseudomonas aeruginosa PAT, J. Bacterial. 133: 1113–1125.

    CAS  Google Scholar 

  344. Watson, M. D., and Scaife, J. G., 1978, Chromosomal transfer promoted by the promiscuous plasmid RP4, Plasmid 1: 226–237.

    Article  PubMed  CAS  Google Scholar 

  345. Watson, M. D., and Scaife, J. G., 1980, Integrative compatibility: Stable coexistence of chromosomally integrated and autonomous derivatives of plasmid RP4, J. Bacteriol. 142: 462–466.

    PubMed  CAS  Google Scholar 

  346. West, S. C., 1992, Enzymes and molecular mechanism of genetic recombination, Annu. Rev. Biochem. 61: 603–640.

    Article  PubMed  CAS  Google Scholar 

  347. West, S. C., and Connolly, B., 1992, Biological roles of Escherichia coli RuvA and RuvC proteins revealed, Mol. Microbiol. 6: 2755–2759.

    Article  PubMed  CAS  Google Scholar 

  348. Willetts, N. S., 1972, Location of the origin of transfer of the sex factor F, J. Bacteriol. 112: 773–778.

    PubMed  CAS  Google Scholar 

  349. Willens, N. S., and Johnson, D., 1981, pED100, a conjugative F plasmid derivative without insertion sequences, Mol. Gen. Genet. 182: 520–522.

    Google Scholar 

  350. Willetts, N., and Skurray, R., 1987, Structure and function of the F factor and mechanism of conjugation, in: Escherichia coli and Salmonella typhimurium. Cellular and Molecular Biology, Vol. 2 ( F. C. Neidhardt, J. L. Ingraham, K. B. Low, B. Magasanik, M., Schaechter, and H. E. Umbarger, eds.), American Society for Microbiology, Washington, D. C., pp. 1110–1133.

    Google Scholar 

  351. Willetts, N., and Wilkins, B., 1984, Processing of plasmid DNA during bacterial conjugation, Microbial. Rev. 48: 24–41.

    CAS  Google Scholar 

  352. Willens, N. S., Crowther, C., and Holloway, B. W., 1981, The insertion sequence IS2] of R68.45 and the molecular basis for mobilization of the bacterial chromosome, Plasmid 6: 30–52.

    Article  Google Scholar 

  353. Willison, J. C., Haddock, B. A., and Paraskeva, C., 1980, Transfer of chromosomal genes mediated by plasmid R68–45 in Paracoccus denitriftcans, Soc. Gen. Microbial. Q. 8: 14.

    Google Scholar 

  354. Willison, J. C., Ahombo, G., Chabert, J., Magnin, J-P., and Vignais, P. M., 1985, Genetic mapping of the Rhodopseudomonas capsulata chromosome shows nonclustering of genes involved in nitrogen fixation, J. Gen. Microbiol. 131: 3001–3015.

    CAS  Google Scholar 

  355. Yakobson, E. A., and Guiney, Jr., D. G., 1984, Conjugal transfer of bacterial chromosomes mediated by the RK2 plasmid transfer origin cloned into transposon TnS, J. Bacteriol. 160: 451–453.

    PubMed  CAS  Google Scholar 

  356. Yoshikawa, M., 1974, Identification and mapping of the replication genes of an R factor, R100–1, integrated into the chromosome of Escherichia coli K-12, J. Bacteriol. 118: 1123–1131.

    PubMed  CAS  Google Scholar 

  357. Youvan, D. C., Elder, J. T., Sandlin, D. E., Zsebo, K., Alder, D. P., Panopoulos, N. J., Marrs, B. L., and Hearst, J. E., 1982, R-prime site-directed transposon Tn7 mutagenesis of the photosynthetic apparatus in Rhodopseudomonas capsulata, J. Mol. Biol. 162: 17–41.

    Article  CAS  Google Scholar 

  358. Yu, P-L., Cullum, J., and Drews, G., 1981, Conjugational transfer systems of Rhodopseudomonas capsulate mediated by R plasmids, Arch. Microbiol. 128: 390–393.

    Article  CAS  Google Scholar 

  359. Zennaro, E., Marconi, A. M., Fochesato, N., Castelli, F., and Ruzzi, M., 1991, Identification and sequencing of a new IS element in Pseudomonas fluorescens strain ST, Pseudomonas 1991, Trieste (Italy), p. 235.

    Google Scholar 

  360. Zhang, C., and Holloway, B. W, 1992, Physical and genetic mapping of the catA region of Pseudomonas aeruginosa, J. Gen. Microbiol. 138: 1097–1107.

    CAS  Google Scholar 

  361. Zieg, J., Maples, V. E, and Kushner, S. R., 1978, Recombination levels of Escherichia coli K-12 mutants deficient in various replication, recombination, or repair genes, J. Bacteriol. 134: 958–966.

    PubMed  CAS  Google Scholar 

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Authors and Affiliations

  1. Mikrobiologisches Institut, Eidgenössische Technische Hochschule, CH-8092, Zürich, Switzerland

    Cornelia Reimmann & Dieter Haas

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  1. Cornelia Reimmann
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  2. Dieter Haas
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  1. Department of Biologic and Materials Sciences, School of Dentistry and Department of Microbiology and Immunology, School of Medicine, The University of Michigan, 48109-0402, Ann Arbor, Michigan, USA

    Don B. Clewell

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Reimmann, C., Haas, D. (1993). Mobilization of Chromosomes and Nonconjugative Plasmids by Cointegrative Mechanisms. In: Clewell, D.B. (eds) Bacterial Conjugation. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-9357-4_6

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  • DOI: https://doi.org/10.1007/978-1-4757-9357-4_6

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