Bacterial Conjugation

  • Don B. Clewell

Table of contents

  1. Front Matter
    Pages i-xvi
  2. Laura S. Frost
    Pages 189-221
  3. Barbara Lewis Kittell, Donald R. Helinski
    Pages 223-242
  4. Stephen K. Farrand
    Pages 255-291
  5. David A. Hopwood, Tobias Kieser
    Pages 293-311
  6. Francis L. Macrina, Gordon L. Archer
    Pages 313-329
  7. Francis L. Macrina
    Pages 331-348
  8. Don B. Clewell, Susan E. Flannagan
    Pages 369-393
  9. Back Matter
    Pages 395-413

About this book


Bacterial plasmids originating in a wide range of genera are being studied from a variety of perspectives in hundreds of laboratories around the globe. These elements are well known for carrying "special" genes that confer important survival properties, frequently neces­ sary under atypical conditions. Classic examples of plasmid-borne genes are those provid­ ing bacterial resistance to toxic substances such as antibiotics, metal ions, and bacte­ riophage. Often included are those determining bacteriocins, which may give the bacterium an advantage in a highly competitive environment. Genes offering metabolic alternatives to the cell under nutritionally stressed conditions are also commonly found on plasmids, as are determinants important to colonization and pathogenesis. It is likely that in many, if not most, cases plasmids and their passenger determinants represent DNA acquired recently by their bacterial hosts, and it is the characteristic mobility of these elements that enables their efficient establishment in new bacterial cells by the process known as conjugation. Whereas many plasmids are fully capable of promoting their own conjugal transfer, others move only with help from coresident elements. The ability of a plasmid to establish itself in a variety of different species is com­ mon, and recent studies have shown that transfer can in some cases occur from bacterial cells to eukaryotes such as yeast.


Chromosom DNA Pili Plasmide bacteria environment molecular mechanisms

Editors and affiliations

  • Don B. Clewell
    • 1
  1. 1.Department of Biologic and Materials Sciences, School of Dentistry and Department of Microbiology and Immunology, School of MedicineThe University of MichiganAnn ArborUSA

Bibliographic information