Abstract
Alkaline phosphatase estimations in human serum* are widely used to diagnose physiological or pathological processes involving the skeleton, the hepatobiliary system, or the placenta.1–13 Alkaline phosphatase activities have also been measured in other biological fluids such as urine, saliva, cerebrospinal fluid, and synovial fluid, though the use of such measurements is not as clearly established in clinical medicine as is that of serum alkaline phosphatase. In addition, activities have been estimated in tissues (especially leukocytes), though few clinical decisions are currently based on such tests.
Note: Consult Tables 9.21–9.26 (pages 685–703) for direct referral to sections of this chapter wherein specific problems encountered in the clinical interpretation of alkaline phosphatase measurements are discussed.
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McComb, R.B., Bowers, G.N., Posen, S. (1979). Clinical Utilization of Alkaline Phosphatase Measurements. In: Alkaline Phosphatase. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2970-1_9
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