Cell Impairment in Aging and Development

  • Vincent J. Cristofalo
  • Emma Holečková

Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 53)

Table of contents

  1. Front Matter
    Pages i-xv
  2. G. M. Martin, C. A. Sprague, T. H. Norwood, W. R. Pendergrass, P. Bornstein, H. Hoehn et al.
    Pages 67-90
  3. Jiří Michl, Mirosalv Tolar, Věra Spurná, Dagmar Řezáčová
    Pages 137-146
  4. R. Azencott, C. Hughes, Y. Courtois
    Pages 147-153
  5. D. L. Knook, E. C. Sleyster, M. J. van Noord
    Pages 155-169
  6. P. D. Wilson, L. M. Franks
    Pages 171-183
  7. M. Macek, H. Tomášová, J. Hurych, D. Řezáčová
    Pages 185-192
  8. V. Pössnerová, M. Macek, F. Heřmanský, J. Fortýnová, S. Jeník, J. Holý et al.
    Pages 193-205
  9. Jaroslava Skřivanová, Františka A. Gadirová, Emma Holečková
    Pages 207-213
  10. C. Rowlatt
    Pages 215-217

About this book

Introduction

lar aging, to which this model contributes, has grown. Apart from reports on work in this almost "classical" diploid cell system, the symposium presents studies using different biological systems with results that have been rewarding as information is obtained on patterns of change that are common to more than one experimental system. Indeed, in recent years much more has been learned about the fate of all different types of intermitotic and postmitotic cells in situ. The symposium has also presented contributions dealing, not directly with aging but with early ontogeny; such information on early developmental changes should certainly shed light on some of the mechanisms involved in aging. We are cognizant of the fact that environmental influences resulting from the complexities of modern civilization may have results that only occur much later, and profoundly affect the lifespan of the organism. There remain, of course, many unanswered questions. Whether there is "physiological" as opposed to "pathological" aging; whether "old" cultures living in unchanged, although not exhausted, medium, are degenerating, not aging; what is involved when "old" fragment cultures regenerate after excision by filling the wound with "young" cells; why some tumor cells in vivo as well as in vitro die while others live; all are questions~eserving of our attention.

Keywords

aging attention bone cell cells development fat kidney retina tissue tumor

Editors and affiliations

  • Vincent J. Cristofalo
    • 1
  • Emma Holečková
    • 2
  1. 1.Wistar Institute of Anatomy and BiologyPhiladelphiaUSA
  2. 2.Institute of PhysiologyCzechoslovak Academy of SciencesPrague 4Czechoslovakia

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-4757-0731-1
  • Copyright Information Springer Science+Business Media New York 1975
  • Publisher Name Springer, Boston, MA
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-4757-0733-5
  • Online ISBN 978-1-4757-0731-1
  • Series Print ISSN 0065-2598
  • Series Online ISSN 2214-8019
  • About this book