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Boundaries between Promotion and Progression during Carcinogenesis

  • Book
  • © 1991

Overview

Editors:
  1. Oscar Sudilovsky

    1. Case Western Reserve University, Cleveland, USA

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    You can also search for this editor in PubMed   Google Scholar

  2. Henry C. Pitot

    1. McArdle Laboratory for Cancer Research, Madison, USA

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    You can also search for this editor in PubMed   Google Scholar

  3. Lance A. Liotta

    1. National Institutes of Health, Bethesda, USA

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Part of the book series: Basic Life Sciences (BLSC, volume 57)

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Table of contents (29 chapters)

  1. Genetic Instability and the Boundaries between Promotion and Progression

    1. Unknown Primary Tumors: An Example of Accelerated (Type 2) Tumor Progression

      • Philip Frost
      Pages 233-240

    2. Summary by Moderator

      • Oscar Sudilovsky, Henry C. Pitot, Lance A. Liotta
      Pages 241-241

  2. Colloquium: At Which Point in Time Does Genetic Instability Occur in the Natural History of Cancer?

    1. Tumor Heterogeneity and Intrinsically Chemoresistant Subpopulations in Freshly Resected Human Malignant Gliomas

      • Joan R. Shapiro, Bipin M. Mehta, Salah A. D. Ebrahim, Adrienne C. Scheck, Paul L. Moots, Martin R. Fiola
      Pages 243-262

    2. Genetic Instability Occurs Sooner Than Expected: Promotion, Progression and Clonality During Hepatocarcinogenesis in the Rat

      • Oscar Sudilovsky, Lucila I. Hinrichsen, Tom K. Hei, Cecilia M. Whitacre, Jian H. Wang, Sriram Kasturi et al.
      Pages 263-277

    3. Clonal Analysis of Neoplastic Transformation in Cultured Diploid Rat Liver Epithelial Cells

      • J. W. Grisham, M.-S. Tsao, L. W. Lee, G. J. Smith
      Pages 279-300

    4. Epigenetic Features of Spontaneous Transformation in the NIH 3T3 Line of Mouse Cells

      • H. Rubin, Kang Xu
      Pages 301-313

  3. The Boundaries between Promotion and Progression in Humans

    1. The Human Melanocyte System as a Model for Studies on Tumor Progression

      • Istvan Valyi-Nagy, Ulrich Rodeck, Roland Kath, Maria Laura Mancianti, Wallace H. Clark, Meenhard Herlyn
      Pages 315-328

    2. Early and Late Events in the Development of Human Breast Cancer

      • Helene S. Smith, Robert Stern, Edison Liu, Chris Benz
      Pages 329-340

    3. Malignant Progression of Harvey RAS Transformed Normal Human Bronchial Epithelial Cells

      • G. H. Yoakum, L. Malan-Shibley, C. C. Harris
      Pages 341-354

    4. Identification and Characterization of Differentially Expressed Genes in Tumor Metastasis: The nm23 Gene

      • Patricia S. Steeg, Generoso Bevilacqua, Mark E. Sobel, Lance A. Liotta
      Pages 355-361

  4. Back Matter

    Pages 363-372
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Keywords

About this book

The pUrpOSE! of this conference was not to define the two areas that are being bound, which might be a well nigh impossible proposition. Rather, its focus was to concentrate on the mechanistic similarities between promotion and progression. Are the areas involved within the boundaries a continuum? Are these two simultaneous processes? Or are some of the affected cells in the stage of promotion when at the same time others have undergone irreversi­ ble changes tha. t position them in the stage of progression? Or are these two stages the same thing, but called by different names? To explore such concepts we assembled investigators with various back­ grounds and asked them to specifically address these and other questions about "The Boundaries", within the context of the session to which they con­ tributed. The conference lasted two and a half days, from Wednesday to Friday. There were at least four speakers per session with morning and after­ noon sessions each day, except on Friday when the meeting ended at noon. The first day, each speaker had 25 minutes to present a position, followed by five minutes of discussion. At the end of the session there were 40 or 50 minutes of exchange on all the issues examined. For the remaining days, there were 25 minutes of presentation and 15 minutes of discussion.

Editors and Affiliations

  • Case Western Reserve University, Cleveland, USA

    Oscar Sudilovsky

  • McArdle Laboratory for Cancer Research, Madison, USA

    Henry C. Pitot

  • National Institutes of Health, Bethesda, USA

    Lance A. Liotta

Bibliographic Information

  • Book Title: Boundaries between Promotion and Progression during Carcinogenesis

  • Editors: Oscar Sudilovsky, Henry C. Pitot, Lance A. Liotta

  • Series Title: Basic Life Sciences

  • DOI: https://doi.org/10.1007/978-1-4684-5994-4

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: Plenum Press, New York 1991

  • Softcover ISBN: 978-1-4684-5996-8Published: 25 November 2012

  • eBook ISBN: 978-1-4684-5994-4Published: 08 March 2013

  • Edition Number: 1

  • Number of Pages: 384

  • Topics: Oncology, Animal Anatomy / Morphology / Histology, Plant Sciences

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