Overview
- This book is open access, which means that you have free and unlimited access
- Includes cutting-edge techniques
- Provides step-by-step detail essential for reproducible results
- Contains key implementation advice from the experts
Part of the book series: Methods in Molecular Biology (MIMB, volume 2434)
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About this book
This open access volume gathers a variety of models, delivery systems, and approaches that can be used to assess RNA technology for exploiting antisense as a therapeutic intervention. Beginning with a section on the design of antisense technology and their delivery, the book continues by covering model systems developed to evaluate efficacy, both in vivo and in vitro, as well as methods to evaluate preclinically the toxicity associated with these new potential drugs, and intellectual property considerations. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Authoritative and practical, Antisense RNA Design, Delivery, and Analysis provides basic knowledge and a large collection of methods to facilitate the workof newcomers to this vibrant and expanding field.
This book was conceived thanks to the network DARTER (Delivery of Antisense RNA Therapeutics). DARTER is funded by the EU Cooperation of Science and Technology (COST), which aims to enhance interaction and collaborations between researchers in Europe and other countries.
Authoritative and practical, Antisense RNA Design, Delivery, and Analysis provides basic knowledge and a large collection of methods to facilitate the workof newcomers to this vibrant and expanding field.
This book was conceived thanks to the network DARTER (Delivery of Antisense RNA Therapeutics). DARTER is funded by the EU Cooperation of Science and Technology (COST), which aims to enhance interaction and collaborations between researchers in Europe and other countries.
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Keywords
Table of contents (28 protocols)
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Front Matter
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Design and Formulation of Antisense Technology
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Front Matter
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In Vitro Model Systems
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Front Matter
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Editors and Affiliations
Bibliographic Information
Book Title: Antisense RNA Design, Delivery, and Analysis
Editors: Virginia Arechavala-Gomeza, Alejandro Garanto
Series Title: Methods in Molecular Biology
DOI: https://doi.org/10.1007/978-1-0716-2010-6
Publisher: Humana New York, NY
eBook Packages: Springer Protocols
Copyright Information: The Editor(s) (if applicable) and The Author(s) 2022
Hardcover ISBN: 978-1-0716-2009-0Published: 26 February 2022
Softcover ISBN: 978-1-0716-2012-0Published: 26 February 2022
eBook ISBN: 978-1-0716-2010-6Published: 25 February 2022
Series ISSN: 1064-3745
Series E-ISSN: 1940-6029
Edition Number: 1
Number of Pages: XVII, 422
Number of Illustrations: 10 b/w illustrations, 59 illustrations in colour
Topics: Behavioral Therapy, Chemistry/Food Science, general, Biomaterials