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Computed Tomography and Magnetic Resonance Imaging

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Molecular Imaging in Oncology

Part of the book series: Recent Results in Cancer Research ((RECENTCANCER,volume 216))

Abstract

Imaging in Oncology is rapidly moving from the detection and size measurement of a lesion to the quantitative assessment of metabolic processes and cellular and molecular interactions. Increasing insights into cancer as a complex disease with involvement of the tumor stroma in tumor pathobiological processes have made it clear that for successful control of cancer, treatment strategies should not only be directed at the cancer cells but should also take aspects of the tumor microenvironment into account. This requires an understanding of the complex molecular and cellular interactions in cancer tissue. Recent developments in imaging technology have increased the possibility to image various pathobiological processes in cancer development and response to treatment. For computed tomography (CT) and magnetic resonance imaging (MRI) various improvements in hardware, software, and imaging probes have lifted these modalities from classical anatomical imaging techniques to techniques suitable to image and quantify various physiological processes and molecular and cellular interactions. Next to a more general overview of possible imaging targets in oncology, this chapter provides an overview of the various developments in CT and MRI technology and some specific applications.

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Authors and Affiliations

  1. Department of Radiology, Royal Papworth Hospital NHS Foundation Trust, Papworth Road, Cambridge Biomediacal Campus, Cambridge, CB2 0AY, UK

    Monique R. Bernsen & Alessandro Ruggiero

  2. Department of Radiology & Nuclear Medicine, Erasmus MC-University Medical Center Rotterdam, PO Box 2040, 3000, Rotterdam, The Netherlands

    Marcel van Straten, Gyula Kotek, Esther A. H. Warnert, Joost C. Haeck, Piotr A. Wielopolski & Gabriel P. Krestin

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    Fabian Kiessling

  3. Department of Radiation Oncology, Ruprecht Karl University, Heidelberg, Germany

    Jürgen Debus

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Bernsen, M.R. et al. (2020). Computed Tomography and Magnetic Resonance Imaging. In: Schober, O., Kiessling, F., Debus, J. (eds) Molecular Imaging in Oncology. Recent Results in Cancer Research, vol 216. Springer, Cham. https://doi.org/10.1007/978-3-030-42618-7_2

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