Caregivers’ and Physicians’ Perspectives on Alpha-Mannosidosis: A Report from Italy Elena VerrecchiaLudovico L. SicignanoRaffaele Manna Commentary 24 November 2020 Pages: 1 - 10
A Patient Charter for Chronic Obstructive Pulmonary Disease John R. HurstTonya WindersMark T. Dransfield Commentary Open access 27 November 2020 Pages: 11 - 23
Dorzolamide/Timolol Fixed Combination: Learning from the Past and Looking Toward the Future Anastasios G. KonstasLeopold SchmettererL. Jay Katz Review Open access 27 October 2020 Pages: 24 - 51
Burden of Anemia in Chronic Kidney Disease: Beyond Erythropoietin Ramy M. HannaElani StrejaKamyar Kalantar-Zadeh Review Open access 29 October 2020 Pages: 52 - 75
A Comprehensive Review of Alternative Therapies for the Management of Chronic Pain Patients: Acupuncture, Tai Chi, Osteopathic Manipulative Medicine, and Chiropractic Care Ivan UritsRuben H. SchwartzOmar Viswanath Review Open access 12 November 2020 Pages: 76 - 89
Radiation-Induced Sarcomas of the Head and Neck: A Systematic Review Andrés Coca-PelazAntti A. MäkitieAlfio Ferlito Review Open access 13 November 2020 Pages: 90 - 108
Clinical Challenges in the Management of Hormone Receptor-Positive, Human Epidermal Growth Factor Receptor 2-Negative Metastatic Breast Cancer: A Literature Review Gayathri NagarajCynthia X. Ma Review Open access 15 November 2020 Pages: 109 - 136
Medical Therapy for Fibroids: What Next for Ulipristal Acetate? Emmanuel EkanemVikram Talaulikar Review Open access 17 November 2020 Pages: 137 - 148
The Effects of Very Low Energy Diets and Low Energy Diets with Exercise Training on Skeletal Muscle Mass: A Narrative Review Arash ArdavaniHariz AzizIskandar Idris Review Open access 19 November 2020 Pages: 149 - 163
Antimicrobial Stewardship in the Intensive Care Unit: The Role of Biomarkers, Pharmacokinetics, and Pharmacodynamics Patrícia MonizLuís CoelhoPedro Póvoa Review Open access 20 November 2020 Pages: 164 - 179
Burden of Chronic Kidney Disease by KDIGO Categories of Glomerular Filtration Rate and Albuminuria: A Systematic Review Molly MurtonDanielle Goff-LeggettKatherine Tuttle Review Open access 24 November 2020 Pages: 180 - 200
A Review of Clinical Guidelines on the Management of Iron Deficiency and Iron-Deficiency Anemia in Women with Heavy Menstrual Bleeding Diana MansourAxel HofmannKristina Gemzell-Danielsson Review Open access 27 November 2020 Pages: 201 - 225
Real-World Evidence to Contextualize Clinical Trial Results and Inform Regulatory Decisions: Tofacitinib Modified-Release Once-Daily vs Immediate-Release Twice-Daily for Rheumatoid Arthritis Stanley B. CohenJeffrey D. GreenbergMaxime Dougados Original Research Open access 09 October 2020 Pages: 226 - 248
Risk Factors for Prognosis in Elderly Patients with Severe Aneurysmal Subarachnoid Hemorrhage: A Retrospective Study Meng QiLidan JiangNing Wang Original Research 22 October 2020 Pages: 249 - 257
Bicentric Retrospective Analysis of en Bloc Resection and Muscularis Mucosae Detection Rate in Non-Muscle Invasive Bladder Tumors: A Real-World Scenario Julian P. StruckMario W. KramerFranz F. Dressler Original Research Open access 22 October 2020 Pages: 258 - 267
Real-World Study Analysing Progression and Survival of Patients with Idiopathic Pulmonary Fibrosis with Preserved Lung Function on Antifibrotic Treatment Saba NoorSaira NawazNazia Chaudhuri Original Research Open access 24 October 2020 Pages: 268 - 277
Visual Evoked Potentials in Joubert Syndrome: A Suggested Useful Method for Evaluating Future Approaches Targeted to Improve Visual Pathways’ Function Giulio RubertoVincenzo ParisiLuciano Quaranta Original Research Open access 24 October 2020 Pages: 278 - 289
Adherence to the Sociedad Española de Oncología Médica (SEOM) Algorithm for the Treatment of Hyponatremia in Oncology Patients in Spain: The ALGA Study Fernando HenaoAranzazu ManzanoRamón de las Peñas Original Research 27 October 2020 Pages: 290 - 303
Telmisartan Plus S-Amlodipine Single-Pill Combination Therapy is Safe and Effective in Patients with Hypertension from Large-Scale Nationwide Surveillance Data in Korea (NOVEL) Study Sang-Ho JoSung-Ji ParkChang-Gyu Park Original Research 27 October 2020 Pages: 304 - 315
A Global Survey of Disease Burden in Patients Who Carry a Diagnosis of Chronic Inflammatory Demyelinating Polyneuropathy Jeffrey A. AllenLisa ButlerAnne Haudrich Original Research Open access 28 October 2020 Pages: 316 - 328
Comparison of Surgical Outcomes Between Microhook Ab Interno Trabeculotomy and Goniotomy with the Kahook Dual Blade in Combination with Phacoemulsification: A Retrospective, Comparative Case Series Ryota AokiKazuyuki HirookaYoshiaki Kiuchi Original Research 28 October 2020 Pages: 329 - 336
The Association Between Switching from Synthroid® and Clinical Outcomes: US Evidence from a Retrospective Database Analysis James V. HennesseyRamon EspaillatPeter Singer Original Research Open access 28 October 2020 Pages: 337 - 349
Myelopreservation with Trilaciclib in Patients Receiving Topotecan for Small Cell Lung Cancer: Results from a Randomized, Double-Blind, Placebo-Controlled Phase II Study Lowell L. HartRenata FerrarottoMaen A. Hussein Original Research Open access 29 October 2020 Pages: 350 - 365
Epidemiology and Treatment of Patients with Rheumatoid Arthritis, Psoriatic Arthritis and Psoriasis in Germany: A Real-World Evidence Study Claudia GrellmannWojciech DombrowskyLars Joeres Original Research Open access 30 October 2020 Pages: 366 - 385
Maternal Delivery at Home: Issues in India Chung-Ya OuMasuma YasminKoustuv Dalal Original Research Open access 30 October 2020 Pages: 386 - 398
Comparative Efficacy and Safety of Different Regimens of Advanced Gastrointestinal Stromal Tumors After Failure Prior Tyrosine Kinase Inhibitors: A Network Meta-Analysis Xue ZhangYueqin LiangJiafu Yin Original Research 01 November 2020 Pages: 399 - 412
Heat Shock Protein 90α Provides an Effective and Novel Diagnosis Strategy for Nasopharyngeal Carcinoma Minjie MaoXueping WangWanli Liu Original Research 03 November 2020 Pages: 413 - 422
Estimating the Year Each State in the United States Will Achieve the World Health Organization’s Elimination Targets for Hepatitis C Mark SulkowskiWei-Han ChengNancy Reau Original Research Open access 03 November 2020 Pages: 423 - 440
Real-World Economic Burden Among Patients With And Without Heart Failure Worsening After Cardiac Resynchronization Therapy Eugene S. ChungJohn RickardMei S. Duh Original Research 03 November 2020 Pages: 441 - 467
Pharmacokinetics and Safety of Single and Multiple Doses of Oral N-Acetylcysteine in Healthy Chinese and Caucasian Volunteers: An Open-Label, Phase I Clinical Study Alberto PapiAndrea F. D. Di StefanoMilko Radicioni Original Research Open access 04 November 2020 Pages: 468 - 478
Effectiveness of Perindopril/Indapamide Single-Pill Combination in Uncontrolled Patients with Hypertension: A Pooled Analysis of the FORTISSIMO, FORSAGE, ACES and PICASSO Observational Studies Csaba András DézsiMaria GlezerCsaba Farsang Original Research 05 November 2020 Pages: 479 - 494
Anticoagulation Favors Thrombus Recanalization and Survival in Patients With Liver Cirrhosis and Portal Vein Thrombosis: Results of a Meta-Analysis Le WangXiaozhong GuoXingshun Qi Original Research Open access 05 November 2020 Pages: 495 - 520
Economic Burden and Management of Systemic Sclerosis-Associated Interstitial Lung Disease in 8 European Countries: The BUILDup Delphi Consensus Study Jesper Rømhild DavidsenJelle MiedemaStéphane Soulard Original Research Open access 06 November 2020 Pages: 521 - 540
Comparative Analysis of the Temporomandibular Joints in Patients with Chronic Periodontitis Using Cone-Beam Computed Tomography (CBCT) Xiaoqian GuoChangyi YangLi Wang Original Research 07 November 2020 Pages: 541 - 549
Pharmacokinetics, Safety and Tolerability of Once-Weekly Subcutaneous Semaglutide in Healthy Chinese Subjects: A Double-Blind, Phase 1, Randomized Controlled Trial Aixin ShiPanpan XieSine Pfeiffer Haugaard Original Research Open access 07 November 2020 Pages: 550 - 561
Real-World Bleeding and Ischemic Events in Asian Patients on P2Y12-Inhibitors After Percutaneous Coronary Intervention: A National Claims Data Analysis Yonggu LeeYoung-Hyo LimJinho Shin Original Research Open access 11 November 2020 Pages: 562 - 578
Tiotropium/Olodaterol Delays Clinically Important Deterioration Compared with Tiotropium Monotherapy in Patients with Early COPD: a Post Hoc Analysis of the TONADO® Trials Klaus F. RabeJames D. ChalmersJadwiga Wedzicha Original Research Open access 11 November 2020 Pages: 579 - 593
Real-World Comparative Effectiveness of Canagliflozin Versus Empagliflozin and Dapagliflozin in Patients with Type 2 Diabetes in the United States Lawrence BlondeCharmi PatelBrahim Bookhart Original Research 12 November 2020 Pages: 594 - 606
Therapy for Apnoea of Prematurity: A Retrospective Study on Effects of Standard Dose and Genetic Variability on Clinical Response to Caffeine Citrate in Chinese Preterm Infants Xin HeJin-Chun QiuRui Cheng Original Research 12 November 2020 Pages: 607 - 626
Brain Imaging Findings and Response to Intravenous Thrombolysis in Posterior Circulation Stroke Tomáš DorňákZuzana SedláčkováPetr Kaňovský Original Research 16 November 2020 Pages: 627 - 639
Treatment Pattern and Outcomes in Newly Diagnosed Multiple Myeloma Patients Who Did Not Receive Autologous Stem Cell Transplantation: A Real-World Observational Study Jianming HeLuke SchmeroldUte Richarz Original Research Open access 19 November 2020 Pages: 640 - 659
Iron Formulations for the Treatment of Iron Deficiency Anemia in Patients with Inflammatory Bowel Disease: A Cost-Effectiveness Analysis in Switzerland Aysegül AksanAlain SchoepferBarnaby Hunt Original Research Open access 20 November 2020 Pages: 660 - 677
Outcomes of a Series of Patients with Post-Prostatectomy Incontinence Treated with an Adjustable Transobturator Male System or Artificial Urinary Sphincter Cristina EsquinasSonia RuizJavier C. Angulo Original Research Open access 23 November 2020 Pages: 678 - 690
Pharmacokinetics and Safety of INL-001 (Bupivacaine HCl) Implants Compared with Bupivacaine HCl Infiltration After Open Unilateral Inguinal Hernioplasty David LeimanGwendolyn NieblerHarold S. Minkowitz Original Research Open access 25 November 2020 Pages: 691 - 706
A Comparison of Real-World Treatment Patterns and Clinical Outcomes in Patients Receiving First-Line Therapy for Unresectable Advanced Gastric or Gastroesophageal Junction Cancer Versus Esophageal Adenocarcinomas Veena ShankaranHong XiaoIan Chau Original Research Open access 26 November 2020 Pages: 707 - 720
Preference for Oral and Injectable GLP-1 RA Therapy Profiles in Japanese Patients with Type 2 Diabetes: A Discrete Choice Experiment Ataru IgarashiBrian Bekker HansenRobin Wyn Original Research Open access 27 November 2020 Pages: 721 - 738
Mirabegron Add-On Therapy to Tamsulosin in Men with Overactive Bladder: Post Hoc Analyses of Efficacy from the MATCH Study Hidehiro KakizakiKyu-Sung LeeOsamu Yamaguchi Original Research Open access 27 November 2020 Pages: 739 - 757
Annual Cost Burden by Level of Relapse Severity in Patients with Multiple Sclerosis Jacqueline NicholasHuanxue ZhouChinmay Deshpande Original Research Open access 27 November 2020 Pages: 758 - 771
Rapid Onset of Efficacy of Baricitinib in Chinese Patients with Moderate to Severe Rheumatoid Arthritis: Results from Study RA-BALANCE Zhan-Guo LiJian-Kang HuChen-Ge Li Brief Report 25 November 2020 Pages: 772 - 781
Design and Rationale of a Randomized, Double-Blind, Placebo-Controlled, Phase 2/3 Study Evaluating Dociparstat in Acute Lung Injury Associated with Severe COVID-19 Joseph A. LaskyJyotsna FuloriaAllen Melemed Study Protocol Open access 27 October 2020 Pages: 782 - 791