Single-Cell Transcriptional Profiling and Gene Regulatory Network Modeling in Tg2576 Mice Reveal Gender-Dependent Molecular Features Preceding Alzheimer-Like Pathologies Muhammad AliOihane Uriarte HuarteEnrico Glaab OriginalPaper Open access 18 August 2022 Pages: 541 - 566
Genetic Ablation of Dentate Hilar Somatostatin-Positive GABAergic Interneurons is Sufficient to Induce Cognitive Impairment Rajasekar NagarajanJinrui LyuUwe Rudolph OriginalPaper 29 August 2023 Pages: 567 - 580
Regulation of Inflammation by IRAK-M Pathway Can Be Associated with nAchRalpha7 Activation and COVID-19 Alessanda S. RiederAngela T. S. Wyse ReviewPaper 29 August 2023 Pages: 581 - 592
Nrf2 Signaling Pathway: a Potential Therapeutic Target in Combating Oxidative Stress and Neurotoxicity in Chemotherapy-Induced Cognitive Impairment Roshan LalRavinder Naik DharavathKanwaljit Chopra ReviewPaper 29 August 2023 Pages: 593 - 608
Locomotor Behavior and Memory Dysfunction Induced by 3-Nitropropionic Acid in Adult Zebrafish: Modulation of Dopaminergic Signaling Melissa Talita WiprichRafaela da Rosa VasquesCarla Denise Bonan OriginalPaper 30 August 2023 Pages: 609 - 621
Inversed Effects of Nav1.2 Deficiency at Medial Prefrontal Cortex and Ventral Tegmental Area for Prepulse Inhibition in Acoustic Startle Response Toshimitsu SuzukiSatoko HattoriKazuhiro Yamakawa OriginalPaper 31 August 2023 Pages: 622 - 634
Effect of Electroacupuncture Stimulation on Proliferation and Differentiation of Endogenous Neural Stem Cells in Rats with Spinal Cord Injury Qilong DengLili MaLizhong Ma OriginalPaper 31 August 2023 Pages: 635 - 645
EGFR-Activated JAK2/STAT3 Pathway Confers Neuroprotection in Spinal Cord Ischemia–Reperfusion Injury: Evidence from High-Throughput Sequencing and Experimental Models Shijie LvKunchi ZhaoFei Yin OriginalPaper 01 September 2023 Pages: 646 - 661
TRPM7 Mediates BSCB Disruption After Spinal Cord Injury by Regulating the mTOR/JMJD3 Axis in Rats Chan Sol ParkJee Youn LeeTae Young Yune OriginalPaper 01 September 2023 Pages: 662 - 677
Asiaticoside Attenuates Blood–Spinal Cord Barrier Disruption by Inhibiting Endoplasmic Reticulum Stress in Pericytes After Spinal Cord Injury Zhenxin HuTingting WuXiliang Tian Original Article 01 September 2023 Pages: 678 - 692
The Shank/ProSAP N-Terminal (SPN) Domain of Shank3 Regulates Targeting to Postsynaptic Sites and Postsynaptic Signaling Daniel WoikeDebora TibbeHans-Jürgen Kreienkamp OriginalPaper Open access 01 September 2023 Pages: 693 - 706
HSP27 Modulates Neuropathic Pain by Inhibiting P2X3 Degradation Ti-Yen YehMing-Fong ChangSung-Tsang Hsieh OriginalPaper 01 September 2023 Pages: 707 - 724
Clinical Correlation of Altered Molecular Signatures in Epileptic Human Hippocampus and Amygdala Sayed Mostafa Modarres MousaviFatemeh AlipourAli Gorji OriginalPaper Open access 02 September 2023 Pages: 725 - 752
Alisol A Exerts Neuroprotective Effects Against HFD-Induced Pathological Brain Aging via the SIRT3-NF-κB/MAPK Pathway Taotao LuLinlin DingXiehua Xue OriginalPaper Open access 02 September 2023 Pages: 753 - 771
Brain-Derived Exosomal miRNA Profiles upon Experimental SAE Rats and Their Comparison with Peripheral Exosomes Qi XiaoXiaoqian YanXiaoyan Zhu OriginalPaper 02 September 2023 Pages: 772 - 782
Regulatory Effects and Mechanisms of L-Theanine on Neurotransmitters via Liver–Brain Axis Under a High Protein Diet Wei XuYuxin SongZhihua Gong OriginalPaper 02 September 2023 Pages: 783 - 798
Identification of Key Genes and Immunological Features Associated with Copper Metabolism in Parkinson’s Disease by Bioinformatics Analysis Haofuzi ZhangJun NagaiXiaofan Jiang OriginalPaper 02 September 2023 Pages: 799 - 811
Downregulation of circAsxl2 Relieves Neuronal Injury Induced by oxygen-glucose deprivation/reperfusion Wen ZhangDan LiuJianmin Fan OriginalPaper 02 September 2023 Pages: 812 - 820
Akkermansia muciniphila Improves Depressive-Like Symptoms by Modulating the Level of 5-HT Neurotransmitters in the Gut and Brain of Mice Huijuan GuoXinxu LiuXiaojie Zhang OriginalPaper Open access 05 September 2023 Pages: 821 - 834
Inhibitor of DNA Binding Protein 3 (ID3) and Nuclear Respiratory Factor 1 (NRF1) Mediated Transcriptional Gene Signatures are Associated with the Severity of Cerebral Amyloid Angiopathy Christian Michael PerezZhenghua GongQuentin Felty OriginalPaper 05 September 2023 Pages: 835 - 882
SIRT6 Improves Hippocampal Neurogenesis Following Prolonged Sleep Deprivation Through Modulating Energy Metabolism in Developing rats Junke JiaWanjiang TaoZongze Zhang OriginalPaper 05 September 2023 Pages: 883 - 899
Exposure to Polystyrene Microplastics Promotes the Progression of Cognitive Impairment in Alzheimer’s Disease: Association with Induction of Microglial Pyroptosis Genghuan WangYingcong LinHeping Shen OriginalPaper 05 September 2023 Pages: 900 - 907
Therapeutic Target MicroRNA Identification Based on Circular RNA Expression Signature After Intracerebral Hemorrhage Jeong-Min KimJangsup MoonKeun-Hwa Jung OriginalPaper 05 September 2023 Pages: 908 - 918
Fecal Microbiota Transplantation-Mediated Ghrelin Restoration Improves Neurological Functions After Traumatic Brain Injury: Evidence from 16S rRNA Sequencing and In Vivo Studies Yamei ZhangJunying LiuLi Ma OriginalPaper 05 September 2023 Pages: 919 - 934
Electroacupuncture Promotes Nerve Regeneration and Functional Recovery Through Regulating lncRNA GAS5 Targeting miR-21 After Sciatic Nerve Injury Ming-yue TianYi-duo YangShui-jin Shao OriginalPaper Open access 06 September 2023 Pages: 935 - 949
Correction: Electroacupuncture Promotes Nerve Regeneration and Functional Recovery Through Regulating lncRNA GAS5 Targeting miR-21 After Sciatic Nerve Injury Ming-yue TianYi-duo YangShui-jin Shao Correction Open access 24 January 2024 Pages: 950 - 952
A Complex Interplay of DJ-1, LRRK2, and Nrf2 in the Regulation of Mitochondrial Function in Cypermethrin-Induced Parkinsonism Alika SarkarMahendra Pratap Singh OriginalPaper 06 September 2023 Pages: 953 - 970
The Transcription Factor Ets1 Influences Axonal Growth via Regulation of Lcn2 Miao GuXiaodi LiXiaosong Gu OriginalPaper Open access 06 September 2023 Pages: 971 - 981
Reinstated Activity of Human Tau-induced Enhanced Insulin Signaling Restricts Disease Pathogenesis by Regulating the Functioning of Kinases/Phosphatases and Tau Hyperphosphorylation in Drosophila PragatiSurajit Sarkar OriginalPaper 07 September 2023 Pages: 982 - 1001
Astrocytic Extracellular Vesicles Regulated by Microglial Inflammatory Responses Improve Stroke Recovery Chikage KijimaToshiki InabaYuji Ueno OriginalPaper Open access 07 September 2023 Pages: 1002 - 1021
Correction to: Astrocytic Extracellular Vesicles Regulated by Microglial Inflammatory Responses Improve Stroke Recovery Chikage KijimaToshiki InabaYuji Ueno Correction Open access 20 September 2023 Pages: 1022 - 1022
Demethylase FTO-Mediated m6A Modification of lncRNA MEG3 Activates Neuronal Pyroptosis via NLRP3 Signaling in Cerebral Ischemic Stroke Honglin YanWenxian HuangJingping Yuan OriginalPaper 07 September 2023 Pages: 1023 - 1043
Deferoxamine Mitigates Ferroptosis and Inflammation in Hippocampal Neurons After Subarachnoid Hemorrhage by Activating the Nrf2/TXNRD1 Axis Junting HuMeixiong ChengQi Wang OriginalPaper 07 September 2023 Pages: 1044 - 1060
Flavopiridol Suppresses Cell Proliferation and Migration and Induces Apoptotic Cell Death by Inhibiting Oncogenic FOXM1 Signaling in IDH Wild-Type and IDH-Mutant GBM Cells Ahsen GulerZuhal HamurcuBulent Ozpolat OriginalPaper 07 September 2023 Pages: 1061 - 1079
Hypoxic Preconditioning Attenuates Neuroinflammation via Inhibiting NF-κB/NLRP3 Axis Mediated by p-MLKL after Transient Global Cerebral Ischemia Xiaomei LuLixuan ZhanEn Xu OriginalPaper 08 September 2023 Pages: 1080 - 1099
Signaling Pathways Involved in the Neuroprotective Effect of Osthole: Evidence and Mechanisms Lovedeep SinghRajbir Bhatti ReviewPaper 08 September 2023 Pages: 1100 - 1118
Ucp4 Knockdown of Cerebellar Purkinje Cells Induces Bradykinesia Ya-Yun WangHui LiuYan-Ling Yang OriginalPaper Open access 09 September 2023 Pages: 1119 - 1139
Gypenoside Pretreatment Alleviates the Cerebral Ischemia Injury via Inhibiting the Microglia-Mediated Neuroinflammation Xue XiaJiahao ChenXiaojing Wang OriginalPaper 09 September 2023 Pages: 1140 - 1156
Targeting Ferroptosis Promotes Functional Recovery by Mitigating White Matter Injury Following Acute Carbon Monoxide Poisoning Shuhong WangBinyuan XiongAnyong Yu OriginalPaper 11 September 2023 Pages: 1157 - 1174
TGN-020 Alleviate Inflammation and Apoptosis After Cerebral Ischemia–Reperfusion Injury in Mice Through Glymphatic and ERK1/2 Signaling Pathway Xiaohong LiZhuoxi XieHao Li OriginalPaper Open access 11 September 2023 Pages: 1175 - 1186
Gemfibrozil Alleviates Cognitive Impairment by Inhibiting Ferroptosis of Astrocytes via Restoring the Iron Metabolism and Promoting Antioxidant Capacity in Type 2 Diabetes Nan WangYujing ZhaoQiang Wang OriginalPaper 11 September 2023 Pages: 1187 - 1201
Cellular and Molecular Roles of Immune Cells in the Gut-Brain Axis in Migraine Yichen ZhouMiaoyi PangFei Yang ReviewPaper 11 September 2023 Pages: 1202 - 1220
Correction to: Kir6.2 Deficiency Promotes Mesencephalic Neural Precursor Cell Differentiation via Regulating miR-133b/GDNF in a Parkinson’s Disease Mouse Model Yan ZhouJialei ZhuGang Hu Correction 15 December 2023 Pages: 1221 - 1222
Correction to: Cyanidin-3-O-Glucoside Regulates the M1/M2 Polarization of Microglia via PPARγ and Aβ42 Phagocytosis Through TREM2 in an Alzheimer’s Disease Model SanjayJae-Ho ShinHae-Jeung Lee Correction Open access 22 December 2023 Pages: 1223 - 1223