Abstract
Purpose
The aim of this study was to perform a systematic review and meta-analysis of the short- and long-term outcomes of stapled haemorrhoidopexy.
Methods
A literature search identified randomised controlled trials comparing stapled haemorrhoidopexy with Milligan–Morgan/Ferguson haemorrhoidectomy. Data were extracted independently for each study and differences analysed with fixed and random effects models.
Results
Thirty-four randomised trials and two systematic reviews were identified, and 29 trials included. Stapled haemorrhoidopexy was statistically superior for hospital stay (p < 0.001) and numerically superior for post-operative pain (peri-operative and mid-term), operation time and bleeding (post-operative and long-term). Recurrent prolapse and re-intervention for recurrence were more frequent following stapled haemorrhoidopexy. No difference was observed in the rates of complications.
Conclusions
Stapled haemorrhoidopexy reduces the length of hospital stay and may have an advantage in terms of decreased operating time, reduced post-operative pain and less bleeding but is associated with an increased rate of recurrent prolapse.
Similar content being viewed by others
References
Hardy A, Chan CLH, Cochen CRG (2005) The surgical management of haemorrhoids—review. Dig Surg 22:26–33
Loder PB, Kamm MA, Nichollsa RJ, Philips RKS (1994) Haemorrhoids: pathology, pathophysiology and etiology. Br J Surg 81:946–954
Johannsson HO, Graf W, Pahlman L (2002) Long term results of hemorrhoidectomy. Eur J Surg 168:485–489
Haas PA, Fox TA Jr, Haas GP (1984) The pathogenesis of haemorrhoids. Dis Colon Rectum 27:442–450
Khalil KH, O’Bichere A, Sellu D (2000) Randomized clinical trial of sutured versus stapled closed haemorrhoidectomy. Br J Surg 87:1352–1355
Andrews BT, Layer GT, Jackson BT, Nicholls RJ (1993) Randomized trial comparing diathermy hemorrhoidectomy with the scissor dissection Milligan–Morgan operation. Dis Colon Rectum 36:580–583
Wang JY, Chang Chien CR, Chen JS, Lai CR, Tang R (1991) The role of lasers in haemorrhoidectomy. Dis Colon Rectum 34:78–82
Jayne DG, Botterill I, Ambrose NS, Brennan TG, Guillou OJ, O’Riodain DS (2002) Randomised clinical trial of ligasure versus conventional diathermy for day case haemorrhoidectomy. Br J Surg 89:428–432
Tan JJ, Seow-Choen F (2001) Prospective randomised trial comparing diathermy and Harmonic Scalpel haemorrhoidectomy. Dis Colon Rectum 44:677–679
Milligan E, Morgan C, Jones L, Officer R (1937) Surgical anatomy of the anal canal, and operative treatment of haemorrhoids. Lancet ii:1129–1124
Ferguson DJ, Heaton JR (1959) Closed haemorrhoidectomy. Dis Colon Rectum 2:176–179
Justin TA, Armitage NC (1999) Haemorrhoidectomy: 5 years later. Br J Surg 86:60, (Abstr)
Longo A (1998) Treatment of haemorrhoid disease by reduction in mucosal and haemorrhoidal products with a circular stapling device—new procedure. Proceedings of the 6th World Congress of Endoscopic Surgery, Rome, Italy
Corman ML, Gravie JF, Hager T, Loudon MA, Mascagni D, Nystrom PO et al (2003) Stapled haemorrhoidopexy: a consensus position paper by an international working party—indications, contraindications and technique. Colorectal Dis 5:304–310
Au-Yong I, Rowsell M, Hemingway DM (2004) Randomised controlled clinical trial of stapled haemorrhoidectomy vs conventional haemorrhoidectomy; a three and a half year follow up. Colorectal Dis 6:37–38
Ganio E, Altomare DF, Gabrielli F, Milito G, Canuti S (2001) Prospective randomized multicentre trial comparing stapled with open haemorrhoidectomy. Br J Surg 88:669–674
Mehigan BJ, Monson JR, Hartley JE (2000) Stapling procedure for haemorrhoids versus Milligan–Morgan haemorrhoidectomy: randomised controlled trial. Lancet 355:782–785
Rowsell M, Bello M, Hemingway DM (2000) Circumferential mucosectomy (stapled haemorrhoidectomy) versus conventional haemorrhoidectomy: randomised controlled trial. Lancet 355:779–781
Schalaby R, Desoky A (2001) Randomized clinical trial of stapled versus Milligan–Morgan haemorrhoidectomy. Br J Surg 88:1049–1053
NICE (2003) National Institute for Clinical Excellence interventional procedures programme. Interventional procedure overview of circular stapled haemorrhoidectomy. http://www.nice.org.uk/pdf/ip/106overview.pdf
Basdanis G, Papdopoulos VN, Michalopoulos A, Apostolidis S, Harlaftis N (2005) Randomized clinical trial of stapled hemorrhoidectomy vs open with Ligasure for prolapsed piles. Surg Endosc 19:235–239
Bickhandani J, Agarwal PN, Kant R, Malik VK (2005) Randomized controlled trial to compare the early and mid-term results of stapled versus open hemorrhoidectomy. Am J Surg 189:56–60
Brown SR, Ballan K, Ho E, Ho Fams YH, Seow-Choen F (2001) Stapled mucosectomy for acute thrombosed circumferentially prolapsed piles: a prospective randomized comparison with conventional haemorrhoidectomy. Colorectal Dis 3:175–178
Cheetham MJ, Cohen CR, Kamm MA, Phillips RK (2003) A randomized, controlled trial of diathermy hemorrhoidectomy vs. stapled hemorrhoidectomy in an intended day-care setting with longer-term follow-up. Dis Colon Rectum 46:491–497
Chung CC, Cheung HYS, Chan ESW, Kwok SY, Li MKW (2005) Stapled hemorrhoidopexy vs Harmonic Scalpel hemorrhoidectomy: a randomized trial. Dis Colon Rectum 48:1213–1219
Correa-Rovelo JM, Tellez O, Obregon L, Miranda-Gomez A, Moran S (2002) Stapled rectal mucosectomy vs. closed hemorrhoidectomy: a randomized, clinical trial. Dis Colon Rectum 45:1367–1374
Gravie JF, Lehur P-A, Huten N, Papillon M, Fantoli M, Descottes B, Pessaux P, Arnaud JP (2005) Stapled hemorrhoidopexy versus Milligan–Morgan hemorrhoidectomy. A prospective, randomized, multicenter trial with 2-year postoperative follow up. Ann Surg 242:29–35
Hetzer FH, Demartines N, Handschin AE, Clavien PA (2002) Stapled vs excision hemorrhoidectomy: long-term results of a prospective randomized trial. Arch Surg 137:337–340
Kairaluoma M, Nuorva K, Kellokumpu I (2003) Daycase stapled (circular) vs. diathermy hemorrhoidectomy. A randomized, controlled trial evaluating surgical and functional outcome. Dis Colon Rectum 46:93–99
Kraemer M, Parulava T, Roblick M, Duschka L, Müller-Lobeck H (2005) Prospective, randomized study: proximate PPH stapler vs. Ligasure for hemorrhoidal surgery. Dis Colon Rectum 48:1517–1522
Krska Z, Kvasnieka J, Faltyn J, Schmidt D, Svab J, Kormanova K, Hubik J (2005) Surgical treatment of haemorrhoids according to Longo and Milligan Morgan: an evaluation of postoperative tissue response. Colorectal Dis 5:573–576
Lau PYY, Meng WCS, Yip AWC (2004) Stapled haemorrhoidectomy in Chinese patients: a prospective randomized control study. Hong Kong Med J 20:373–377
Maw A, Concepcion Eu KW, Seow-Choen F, Heah SM, Tang CL, Tan AL (2003) Prospective randomized study of bacteraemia in diathermy and stapled haemorrhoidectomy. Br J Surg 90:222–226
Ortiz H, Marzo J, Armendariz P (2002) Randomized clinical trial of stapled haemorrhoidopexy versus conventional diathermy haemorrhoidectomy. Br J Surg 89:1376–1381
Ortiz H, Marzo J, Armendariz P, De Miguel M (2005) Stapled hemorrhoidopexy vs. diathermy excision for fourth-degree hemorrhoids: a randomized, clinical trial and review of the literature. Dis Colon Rectum 48:809–815
Palimento D, Picchio M, Attanasio U, Lombardi A, Bambini C, Renda A (2003) Stapled and open hemorrhoidectomy: randomized controlled trial of early results. World J Surg 27:203–207
Pavlidis T, Papaziogas B, Souparis A, Patsas A, Koutelidakis I, Papaziogas T (2002) Modern stapled Longo procedure vs. conventional Milligan–Morgan hemorrhoidectomy: a randomized controlled trial. Int J Colorectal Dis 17:50–53
Picchio M, Palimento D, Attanasio U, Renda A (2006) Stapled vs open hemorrhoidectomy: long-term outcome of a randomized controlled trial. Int J Colorectal Dis 21:668–669
Racabulto A, Aliotta I, Corsaro G, Lanteri R, Di Cataldo A, Licata A (2004) Hemorrhoidal stapler prolapsectomy vs. Milligan–Morgan hemorrhoidectomy: a long-term randomized trial. Int J Colorectal Dis 19:239–244
Senagore AJ, Singer MS, Abcarian H, Fleshman J, Corman M, Wexner S, Nivatvongs S (2004) A prospective, randomized, controlled multicenter trail comparing stapled hemorrhoidopexy and Ferguson hemorrhoidectomy: perioperative and one-year results. Dis Colon Rectum 47:1824–1836
Smyth EF, Baker RP, Wilken BJ, Hartley JE, White T, Monson JRT (2003) Stapled versus excision haemorrhoidectomy: long term follow up of a randomized controlled trial. Lancet 361:1437–1438
Stadt van de J, D’Hoore A, Duinslaeger M, Chasse E, Pennickx F (2005) Long-term results after excision haemorrhoidectomy versus stapled haemorrhoidopexy for prolapsing haemorrhoids. A Belgian prospective randomized trial. Acta Chir Belg 105:44–52
Wilson MS, Pope V, Doran HE, Fearn SJ, Brough WA (2002) Objective comparison of stapled anopexy and open hemorrhoidectomy. Dis Colon Rectum 45:1437–1438
Ho YH, Cheong WK, Tsang C, Ho J, Eu KW, Tang CL, Seow-Choen F (2000) Stapled hemorrhoidectomy—cost and effectiveness. Randomized, controlled trial including incontinence scoring, anorectal manometry, and endoanal ultrasound assessments at up to three months. Dis Colon Rectum 43:1666–1675
Kirsch JJ, Staude G, Herold A (2001) Hämorrhoidektomien nach Longo und Milligan–Morgan. Prospektive Vergleichstudie mit 300 Patienten. Chirurg 72:180–185
Boccasanta P, Capretti P, Venturi M, Cioffi U, De Simone M, Salamina G et al (2001) Randomised controlled trial between stapled circumferential mucosectomy and conventional circular hemorrhoidectomy in advanced hemorrhoids with external mucosal prolapse. Am J Surg 182:64–68
Hasse C, Sitter H, Brune M, Wollenteit I, Lorenz W, Rothmund M (2004) Hämorrhoidektomie: Konventionelle Exzision versus Resektion mit dem Klammernahtgerät. Dtsch Med Wochenschr 129:1611–1617
Ascanelli S, Gregorio C, Tonini G, Baccarini M, Azzena G (2005) Longo stapled haemorrhoidectomy versus Milligan–Morgan procedure: short- and long-term results of a randomised, controlled, prospective trial. Chirurgia Italiana 57:439–447
Nisar PJ, Acheson AG, Neal KR, Scholefield JH (2004) Stapled hemorrhoidopexy compared with conventional hemorrhoidectomy: systematic review of randomized controlled trials. Dis Colon Rectum 47:1837–1845
Lan P, Wu X, Zhou X, Wang J, Zhang L (2006) The safety and efficacy of stapled hemorrhoidectomy in the treatment of hemorrhoids: a systematic review and meta-analysis of ten randomized control trials. Int J Colorectal Disease 21:172–178
ASERNIP-S (2002). A systematic review of stapled haemorrhoidectomy. http://www.surgeons.org/asernip-s/systematic_review/SHreview0202.pdf
Author information
Authors and Affiliations
Corresponding author
Additional information
Financial support
Statistical support was provided courtesy of Ethicon Endosurgery (Europe).
Previous communication
The contents of this manuscript have not been previously communicated to a society or meeting.
Rights and permissions
About this article
Cite this article
Laughlan, K., Jayne, D.G., Jackson, D. et al. Stapled haemorrhoidopexy compared to Milligan–Morgan and Ferguson haemorrhoidectomy: a systematic review. Int J Colorectal Dis 24, 335–344 (2009). https://doi.org/10.1007/s00384-008-0611-0
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00384-008-0611-0