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Genetic Transformation of Zygomycetes Fungi

  • Chapter
Progress in Mycology

Abstract

Zygomycetes fungi, especially members of the order Mucorales and Mortierellales are important from various biological, biotechnological and medical aspects. They are used as model organisms to answer biological questions in the fields of sexual differentiation (Sutter, 1975; Kuzina and Cerdá- Olmedo, 2006; Idnurm et al., 2008), morphological dimorphism (Lübbehüsen et al., 2003; Iturriaga et al., 2005), biosynthesis of carotenoids (Iturriaga et al., 2000; Sanz et al., 2002; Kuzina et al, 2006; Almeida and Cerdá-Olmedo, 2008) or the light induction of gene regulation and metabolite production (Velayos et al., 2003; Quiles-Rosillo et al., 2005; Idnurm et al., 2006). Phycomyces blakesleeanus, Mucor circinelloides, M. mucedo, Rhizopus oryzae and Absidia glauca are the best-studied species. Rhizopus, Mucor and Gilbertella species may also be important causing post-harvest losses in agricultural products, or as spoilage microorganisms of certain foods (Csernetics et al., 2005). Several species belonging to the genera Rhizopus, Absidia, Rhizomucor, Mucor, Apophysomyces, Saksanea, Cunninghamella, Cokeromyces and Syncephalastrum are known as causative agents of frequently fatal opportunistic fungal infections in immunocompromised patients called as zygomycoses (Ribes et al., 2000; Chayakulkeeree et al., 2006; Papp et al., 2008). High mortality rates, difficulties in the diagnosis and non-treatability with the most widely used antifungal drugs are characteristic features of such infections. Studies on the molecular and genetic background of the pathogenicity of these fungi started only a few years ago (Papp et al., 2008).

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Authors and Affiliations

  1. department of Microbiology, Faculty of Science and Informatics, University of Szeged, H-6726 Szeged, Közép fasor 52, Hungary

    TamÁs Papp, ÁrpÁd Csernetics & IldikÓ Nyilasi

  2. Central Laboratory of Clinical Microbiology, Albert Szent-Györgyi Medical Centre, University of Szeged, 6725 Szeged, Semmelweis u 6, Hungary

    Marianna ÁBrÓk & Csaba VÁgvÓlgyi

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  2. ÁrpÁd Csernetics
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  3. IldikÓ Nyilasi
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  4. Marianna ÁBrÓk
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  5. Csaba VÁgvÓlgyi
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Editors and Affiliations

  1. Department of Biotechnology, SGB Amravati University, Maharashtra, India

    Mahendra Rai (Professor and Head) (Professor and Head)

  2. Department of Plant Protection, Debrecen University, Debrecen, Hungary

    George Kövics (Professor and Head) (Professor and Head)

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© 2010 Scientific Publishers (India)

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Papp, T., Csernetics, Á., Nyilasi, I., ÁBrÓk, M., VÁgvÓlgyi, C. (2010). Genetic Transformation of Zygomycetes Fungi. In: Rai, M., Kövics, G. (eds) Progress in Mycology. Springer, Dordrecht. https://doi.org/10.1007/978-90-481-3713-8_3

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