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Microvascular Networks and Models, In vitro Formation

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Vascularization for Tissue Engineering and Regenerative Medicine

Part of the book series: Reference Series in Biomedical Engineering ((TIENRE))

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Abstract

The microvasculature involves the part of the vascular system made of vessels with diameters inferior to 100 μm. There are many culture models allowing for the formation of microvascular networks in vitro, developed either to study cellular and/or molecular aspects of angiogenesis and vasculogenesis or to prevascularize engineered tissues. In this chapter, we describe the cellular (Sect. 2) and material (Sect. 3) components used to generate such in vitro models. Innovative, advanced bioengineering processes, based on bioprinting or microfluidics, to create microvascular networks are also described (Sect. 4).

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Authors and Affiliations

  1. University Hospital Zurich, Zurich, Switzerland

    Ulrich Blache

  2. Department of Biomedicine, University Hospital Basel, University of Basel, Basel, Switzerland

    Julien Guerrero & Arnaud Scherberich

  3. Izmir Biomedicine and Genome Institute and Center, Dokuz Eylul University, Izmir, Turkey

    Sinan Güven

  4. University Children’s Hospital in Zurich, Zurich, Switzerland

    Agnes Silvia Klar

  5. Department of Biomedical Engineering, University of Basel, Allschwil, Switzerland

    Arnaud Scherberich

  6. Department of Plastic, Reconstructive, Aesthetic and Hand Surgery, University Hospital Basel, Basel, Switzerland

    Arnaud Scherberich

Authors
  1. Ulrich Blache
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  2. Julien Guerrero
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  3. Sinan Güven
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  4. Agnes Silvia Klar
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  5. Arnaud Scherberich
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Corresponding author

Correspondence to Arnaud Scherberich .

Editor information

Editors and Affiliations

  1. AUVA Research Center, Ludwig Boltzmann Inst. Exp. a. Clinical AUVA Research Center, Wien, Holy See (Vatican City State)

    Wolfgang Holnthoner

  2. Department of Biomedicine, University Hospital Basel Department of Biomedicine, Basel, Switzerland

    Andrea Banfi

  3. Institute for Pathology, Johannes Gutenberg University Institute for Pathology, Mainz, Germany

    James Kirkpatrick

  4. LBI für experimentelle und klinisch , Wien, Austria

    Heinz Redl

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© 2018 Springer International Publishing AG

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Blache, U., Guerrero, J., Güven, S., Klar, A.S., Scherberich, A. (2018). Microvascular Networks and Models, In vitro Formation. In: Holnthoner, W., Banfi, A., Kirkpatrick, J., Redl, H. (eds) Vascularization for Tissue Engineering and Regenerative Medicine. Reference Series in Biomedical Engineering(). Springer, Cham. https://doi.org/10.1007/978-3-319-21056-8_9-1

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  • DOI: https://doi.org/10.1007/978-3-319-21056-8_9-1

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-21056-8

  • Online ISBN: 978-3-319-21056-8

  • eBook Packages: Springer Reference EngineeringReference Module Computer Science and Engineering

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