Table of contents

  1. Victor W. M. van Hinsbergh
  2. Sabrina Rohringer, Mira Schaupper, Wolfgang Holnthoner
  3. Luba Perry, Shahar Ben-Shaul, Shira Landau, Shulamit Levenberg
  4. Alexander Haumer, Tarek Ismail, Alexander Lunger, Rik Osinga, Arnaud Scherberich, Dirk Johannes Schaefer et al.
  5. Laxminarayanan Krishnan, Steven A. LaBelle, Marissa A. Ruehle, Jeffrey A. Weiss, James B. Hoying, Robert E. Guldberg
  6. Christoph Koepple, Ulrich Kneser, Volker J. Schmidt
  7. Ulrich Blache, Julien Guerrero, Sinan Güven, Agnes Silvia Klar, Arnaud Scherberich
  8. S. Chaudary, S. Rieger, H. Redl, P. Dungel

About this book


This reference work presents the basic principles of angiogenesis induction, including the roles of signaling factors such as hypoxia-inducible factors, biophysical stimulation and angiogenic cells. The book also covers lymphogenesis induction. Both the established  fundamentals in the field as well as new trends in the vascularization of engineered tissues are discussed. These include pre-vascularization strategies using preparation of channeled scaffolds and preparation of decellularized blood vessel trees, approaches to inducing formation of microvasculature and approaches to inducing the growth of vascular networks. The authors expand on these concepts with current studies of dual-level approaches to engineer vascularized tissue composites.
The book concludes with a discussion of current clinical approaches and the use of vascular grafts in the context of providing clinical practice with new tissue engineering strategies.

Editors and affiliations

  • Wolfgang Holnthoner
    • 1
  • Andrea Banfi
    • 2
  • James Kirkpatrick
    • 3
  • Heinz Redl
    • 4
  1. 1.AUVA Research CenterLudwig Boltzmann Inst. Exp. a. Clinical AUVA Research CenterWienHoly See (Vatican City State)
  2. 2.Department of BiomedicineUniversity Hospital Basel Department of BiomedicineBaselSwitzerland
  3. 3.Institute for PathologyJohannes Gutenberg University Institute for PathologyMainzGermany
  4. 4.LBI für experimentelle und klinisch WienAustria

Bibliographic information

  • DOI
  • Copyright Information Springer Nature Switzerland AG 2019
  • Publisher Name Springer, Cham
  • eBook Packages Engineering
  • Online ISBN 978-3-319-21056-8