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Table of contents (45 chapters)
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The Mystery and History of Magnetism
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Preparation and Modification of Biodegradable Magnetic Particles
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Characterization of Magnetic Particles
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Applications in Molecular Biology
Keywords
About this book
The discovery of uniform latex particles by polymer chemists of the Dow Chemical Company nearly 50 years ago opened up new exciting fields for scientists and physicians and established many new biomedical applications. Many in vitro diagnostic tests such as the latex agglutination tests, analytical cell and phagocytosis tests have since become rou tine. They were all developed on the basis of small particles bound to biological active molecules and fluorescent and radioactive markers. Further developments are ongoing, with the focus now shifted to applications of polymer particles in the controlled and di rected transport of drugs in living systems. Four important factors make microspheres interesting for in vivo applications: First, biocompatible polymer particles can be used to transport known amounts of drug and re lease them in a controlled fashion. Second, particles can be made of materials which bio degrade in living organisms without doing any harm. Third, particles with modified surfaces are able to avoid rapid capture by the reticuloendothelial system and therefore en hance their blood circulation time. Fourth, combining particles with specific molecules may allow organ-directed targeting.
Editors and Affiliations
Bibliographic Information
Book Title: Scientific and Clinical Applications of Magnetic Carriers
Editors: Urs Häfeli, Wolfgang Schütt, Joachim Teller, Maciej Zborowski
DOI: https://doi.org/10.1007/978-1-4757-6482-6
Publisher: Springer New York, NY
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eBook Packages: Springer Book Archive
Copyright Information: Springer Science+Business Media New York 1997
Hardcover ISBN: 978-0-306-45687-9Published: 31 July 1997
Softcover ISBN: 978-1-4419-3283-9Published: 01 December 2010
eBook ISBN: 978-1-4757-6482-6Published: 11 November 2013
Edition Number: 1
Number of Pages: XV, 628