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Quantification of Maghemite Nanoparticles in Biological Media by Ferromagnetic Resonance and Its Alteration by Conjugation with Biological Substances

  • Maria de Fatima Da Silva
  • François Gendron
  • Jean Claude Bacri
  • Jacky Roger
  • Jean-Noël Pons
  • Michel Robineau
  • Domagoj Sabolovic’
  • Avraham Halbreich
Chapter

Abstract

The measurement of the cooperative magnetic moment of maghemite based nanoparticles (FF) by ferromagnetic resonance (FMR) enabled the detection of as little as 100 pmoles of particulate iron in a 2 pl biological sample without interference from soluble endogenous iron, thus enabling us to follow the biodistribution of injected FF in vivo.

Keywords

Magnetic Nanoparticles Magnetic Fluid Ferromagnetic Resonance Resonance Field MAGHEMITE NANOPARTICLES 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    Rosensweig RE (1985). Ferrohydrodynamics. University Press, New York.Google Scholar
  2. 2.
    Da Silva MF and Figueiredo Neto AM (1993). Optical and X-ray scattering studies of ionic ferrofluids of MnFe 2 O 4,γFe 2 0 3 , and CoFe 3 O 4. Phys Revs E 48, 4483–4491.ADSCrossRefGoogle Scholar
  3. 3.
    Neveu Prin S, Tourinho FA, Bacri JC et al (1993). Magnetic birefringence of cobalt and ferrite ferrofluid. Colloids and surface A. Physicochemical and Engineering Aspects80, I-11.CrossRefGoogle Scholar
  4. 4.
    Charles SW (1988). Aggregation in magnetic fluids and magnetic fluid composites. Chem Eng Commun 67, 145–180.CrossRefGoogle Scholar
  5. 5.
    Bacri JC, Cebers AO and Perzynski R (1994). Behavior of magnetic fluid drops in a rotating magnetic field. Phys Rev Lett 72, 2705–2708.ADSCrossRefGoogle Scholar
  6. 6.
    Massait R (1982). Magnetic fluids and process for obtaining them. US Patent 4 329 241.Google Scholar
  7. 7.
    Halbreich A, Roger J, Pons JN et al (1997). Magnetic maghemite nanoparticles: their preparation, properties and application in cell sorting and characterization of cellular membranes in vitro. This volume pp. 399–417.Google Scholar
  8. 8.
    Gazeau F (1997). Dynamiques magnétiques et browniennes des nanoparticules d’un ferrofluide. Thèse de doctorat, Université Paris 7, (présentée le 7 janvier 1997).Google Scholar
  9. 9.
    Kodama RH, Berkowitz AE, McNiff EJ Jr. and Foner S (1996). Surface spin disorder in NiFe 2 0 4 nanoparticles. Physical Review Letters 77: 394–397.ADSCrossRefGoogle Scholar
  10. 10.
    Raynal P and Pollard HB (1994). Annexins: the problem of assessing the biological role fora gene family of multifunctional calcium-and phospholipid-binding proteins. Biochim. Biophys. Acta 1197, 63–93.CrossRefGoogle Scholar
  11. 11.
    Sestier C, Sabolovic’ D, Geldwerth D et al (1995). Use of annexin V ferrofluid to enumerate erythrocytes damaged in various pathologies or during storage in vitro. Comptes Rendus Academies des Sciences Paris 318, 1141–1146.Google Scholar
  12. 12.
    Schroit AJ, Madsen JW and Tanaka Y (1985). In vivo recognition and clearance of red blood cells containing phosphatidylserine in their plasma membrane. J. Biol. Chem. 260, 5131–5138.Google Scholar

Copyright information

© Springer Science+Business Media New York 1997

Authors and Affiliations

  • Maria de Fatima Da Silva
    • 1
    • 2
  • François Gendron
    • 2
  • Jean Claude Bacri
    • 3
  • Jacky Roger
    • 3
  • Jean-Noël Pons
    • 3
  • Michel Robineau
    • 3
  • Domagoj Sabolovic’
    • 1
  • Avraham Halbreich
    • 1
  1. 1.INSERM Unité 313CHU Pitié — SalpétrièreParis CedexFrance
  2. 2.Laboratoire d’Acoustique et Optique de la Matière CondenséeUniversité Pierre-et-Marie CurieParis Cedex 05France
  3. 3.Laboratoire de Physico-Chimie InorganiqueUniversité Pierre-et-Marie CurieParis Cedex 05France

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