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The Immunology of Infant Feeding

  • A. W. Wilkinson

Part of the Ettore Majorana International Science Series book series (volume 8)

Table of contents

  1. Front Matter
    Pages i-viii
  2. John Bienenstock
    Pages 1-11
  3. E. T. Swarbrick
    Pages 13-22
  4. R. J. Levinsky, R. Paganelli, D. M. Robertson, D. J. Atherton
    Pages 23-30
  5. J. J. Bullen
    Pages 31-39
  6. C. L. Bullen
    Pages 41-53
  7. David Tyrrell
    Pages 55-62
  8. J. F. Soothill
    Pages 63-69
  9. M. W. Steward, Madeleine E. Devey, M. C. Reinhardt
    Pages 97-106
  10. L. Å. Hanson, B. Carlsson, F. Jalil, B. S. Lindblad, A-M. Svennerholm
    Pages 137-144
  11. Back Matter
    Pages 145-151

About this book

Introduction

Though much thought is given to nutritional aspects of infant feeding, the complex immunological aspects have not been considered adequately, not only in the acceptance of the change to artificial feeding during this century, but also in developing feeds for total or supplementary feeding which will do minimal immunological damage. Besides food, mother's milk gives an orchestra of complex interacting bacteriostatic, bactericidal and anti-viral substances which contribute to the establishment of the normal intestinal flora. These mechanisms probably explain the many reports that breast fed babies get fewer infections than those fed artificially; deprivation from this effect of artificial feeding can be devastating in developing countries, with limited hygienic facilities, bad water supplies and sanitation. Infection is also more frequent in artificially fed infants in developed countries. Ingesting antigens is an important step in initiating the immune response, but the reSponse to such antigens is a controlled one, and besides antibody and cell mediated responses, partial tolerance, and immune exclusion (reduction of subsequent entry of antigen) occur. It is likely that food allergy, grossly neglected until recently, arises from disturbance of such mechanisms in the genetically vulnerable (immunodeficient) child.

Keywords

antibody antigen immune response immunology infection infections

Editors and affiliations

  • A. W. Wilkinson
    • 1
  1. 1.Institute of Child HealthUniversity of LondonLondonEngland

Bibliographic information